2R2M

2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	ENRAF-NONIUS FR591
Detector technology	IMAGE PLATE
Collection date	2001-03-06
Detector	RIGAKU RAXIS II
Spacegroup name	C 1 2 1
Unit cell lengths	70.950, 72.135, 72.850
Unit cell angles	90.00, 100.64, 90.00

Refinement procedure

Resolution	20.000 - 2.100
Rwork	0.168
R-free	0.21400
RMSD bond length	0.004
RMSD bond angle	0.599
Phasing software	X-PLOR
Refinement software	PHENIX

Data quality characteristics

	Overall
Low resolution limit [Å]	20.000
High resolution limit [Å]	2.100
Number of reflections	18902

Crystallization Conditions

crystal ID	method	pH	temperature	details
1