2NRU
Crystal structure of IRAK-4
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 19-ID |
| Synchrotron site | APS |
| Beamline | 19-ID |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 145.303, 141.292, 88.423 |
| Unit cell angles | 90.00, 125.80, 90.00 |
Refinement procedure
| Resolution | 90.290 - 2.000 |
| R-factor | 0.23665 |
| Rwork | 0.233 |
| R-free | 0.29880 |
| Structure solution method | SAD |
| RMSD bond length | 0.021 |
| RMSD bond angle | 2.107 |
| Refinement software | REFMAC (5.2.0019) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 90.290 |
| High resolution limit [Å] | 2.000 |
| Number of reflections | 92544 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | EVAPORATION | 6.4 | 293 | 2.6 - 2.9 M ammonium sulfate, PH 6.4-7.9, EVAPORATION, temperature 293K |
