1XVP

crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 17-ID
Synchrotron site	APS
Beamline	17-ID
Temperature [K]	100
Detector technology	CCD
Collection date	2004-02-13
Detector	ADSC QUANTUM 4
Wavelength(s)	1.00
Spacegroup name	P 32 2 1
Unit cell lengths	128.020, 128.020, 212.175
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	50.000 - 2.600
R-factor	0.18
Rwork	0.180
R-free	0.23400
Structure solution method	MOLECULAR REPLACEMENT
Data reduction software	HKL-2000
Data scaling software	SCALEPACK
Phasing software	CNS
Refinement software	CNS

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	50.000	2.700
High resolution limit [Å]	2.600	2.600
Rmerge	0.045	0.418
Number of reflections	53979
<I/σ(I)>	39.8	2.7
Completeness [%]	86.3	73.4
Redundancy	6	3

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	8	277	Lisium sulphate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K