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9FG2
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BU of 9fg2 by Molmil
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the long-lived symmetric desensitised state
Descriptor: (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the long-lived symmetric desensitised state
To Be Published
9FG3
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BU of 9fg3 by Molmil
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 bound twice in the long-lived symmetric desensitised state
Descriptor: (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 bound twice in the long-lived symmetric desensitised state
To Be Published
9FG4
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BU of 9fg4 by Molmil
Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in the long-lived symmetric resting state
To Be Published
9FG5
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BU of 9fg5 by Molmil
Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in complex with GABA in the short-lived symmetric pre-active state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in complex with GABA in the short-lived symmetric pre-active state
To Be Published
9FG6
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BU of 9fg6 by Molmil
Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in complex with GABA and HSM in the long-lived symmetric desensitised state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3 GABA(A) receptor in complex with GABA and HSM in the long-lived symmetric desensitised state
To Be Published
9FG7
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BU of 9fg7 by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA in the short-lived symmetric pre-active state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA in the short-lived symmetric pre-active state
To Be Published
9FG8
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BU of 9fg8 by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA in the long-lived symmetric desensitised state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA in the long-lived symmetric desensitised state
To Be Published
9FG9
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BU of 9fg9 by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Etomidate in the long-lived symmetric desensitised state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Etomidate in the long-lived symmetric desensitised state
To Be Published
9FGA
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BU of 9fga by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to two PIP2 molecules and in complex with Mb38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to two PIP2 molecules and in complex with Mb38
To Be Published
9FGB
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BU of 9fgb by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-A and in complex with Mb38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-A and in complex with Mb38
To Be Published
9FGC
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BU of 9fgc by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-D and in complex with Mb38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-D and in complex with Mb38
To Be Published
9FGD
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BU of 9fgd by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs without PIP2 and in complex with Mb38
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs without PIP2 and in complex with Mb38
To Be Published
9FGF
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BU of 9fgf by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc in the long-lived symmetric resting state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc in the long-lived symmetric resting state
To Be Published
9FGG
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BU of 9fgg by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc bound to GABA and Etomidate in the long-lived symmetric desensitised state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc bound to GABA and Etomidate in the long-lived symmetric desensitised state
To Be Published
9FGH
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BU of 9fgh by Molmil
Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in large MSP2N2 nanodisc in complex with GABA in the long-lived symmetric desensitised state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Mihaylov, D.B, Malinauskas, T, Aricescu, A.R.
Deposit date:2024-05-23
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in large MSP2N2 nanodisc in complex with GABA in the long-lived symmetric desensitised state
To Be Published
9FGJ
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BU of 9fgj by Molmil
Cryo-EM structure of Legionella effector SdeC (PDE-mART domain)
Descriptor: SdeC
Authors:Weng, T.-H, Misra, M, Chen, W, Safarian, S, Kudryashev, M, Dikic, I.
Deposit date:2024-05-24
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:BAR-like C-terminal domain of Legionella SidE family is crucial for its membrane localization and secretion
To Be Published
9FGM
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BU of 9fgm by Molmil
Cryo-EM structure of Legionella effector SdeC (3D flexible refinement)
Descriptor: SdeC
Authors:Weng, T.-H, Misra, M, Chen, W, Safarian, S, Kudryashev, M, Dikic, I.
Deposit date:2024-05-24
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (4 Å)
Cite:BAR-like C-terminal domain of Legionella SidE family is crucial for its membrane localization and secretion
To Be Published
9FRU
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BU of 9fru by Molmil
Crystal structure of human Sirt2 in complex with a pyrazole-based fragment inhibitor and NAD+
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, NAD-dependent protein deacetylase sirtuin-2, ...
Authors:Friedrich, F, Einsle, O, Jung, M.
Deposit date:2024-06-19
Release date:2025-06-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions.
J.Med.Chem., 2025
9FTT
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BU of 9ftt by Molmil
Cryo-EM structure of the type 1 pilus rod as part of the FimA-bound usher complex (FimDHGFAnC)
Descriptor: Type-1 fimbrial protein, A chain
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-06-25
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the type 1 pilus rod as part of the FimA-bound usher complex (FimDHGFAnC)
To Be Published
9FW9
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BU of 9fw9 by Molmil
Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (FimDHGFAnC - body 2)
Descriptor: Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ...
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-06-28
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (FimDHGFAnC - body 2)
To Be Published
9FWB
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BU of 9fwb by Molmil
Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn and FimAn-1)
Descriptor: Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ...
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-06-28
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn and FimAn-1)
To Be Published
9FWZ
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BU of 9fwz by Molmil
Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn, FimAn-1 and FimAn-2)
Descriptor: Chaperone protein FimC, Outer membrane usher protein FimD, Type-1 fimbrial protein, ...
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-07-01
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the type 1 pilus assembly platform as part of the FimA-bound chaperone-usher pilus complex (Local refinement including FimD, FimC, FimAn, FimAn-1 and FimAn-2)
To Be Published
9FX0
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BU of 9fx0 by Molmil
Cryo-EM structure of the type 1 pilus tip-to-rod transition
Descriptor: Protein FimF, Type-1 fimbrial protein, A chain
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-07-01
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of the type 1 pilus tip-to-rod transition
To Be Published
9FX8
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BU of 9fx8 by Molmil
Cryo-EM structure of the FimI-bound type 1 pilus assembly platform complex - Local refinement
Descriptor: Chaperone protein FimC, Fimbrin-like protein FimI, Outer membrane usher protein FimD
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-07-01
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the FimI-bound type 1 pilus assembly platform complex - Local refinement
To Be Published
9FXA
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BU of 9fxa by Molmil
Cryo-EM structure of the type 1 pilus rod as part of the FimI-bound usher complex (FimDHGFAnIC - body 1)
Descriptor: Type-1 fimbrial protein, A chain
Authors:Bachmann, P, Afanasyev, P, Boehringer, D, Glockshuber, R.
Deposit date:2024-07-01
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of the type 1 pilus rod as part of the FimI-bound usher complex (FimDHGFAnIC - body 1)
To Be Published

236963

數據於2025-06-04公開中

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