9FGG

Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc bound to GABA and Etomidate in the long-lived symmetric desensitised state

This is a non-PDB format compatible entry.

Summary for 9FGG

• Entry DOI: 10.2210/pdb9fgg/pdb
• EMDB information: 50400
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, DECANE, CHLORIDE ION, ... (15 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 295475.18

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in Saposin A nanodisc bound to GABA and Etomidate in the long-lived symmetric desensitised state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.6 Å)