9FGB

Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-A and in complex with Mb38

Summary for 9FGB

• Entry DOI: 10.2210/pdb9fgb/pdb
• EMDB information: 50391
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3, ... (10 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 336023.57

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in SMALPs bound to one PIP2 molecule at chain alpha1-A and in complex with Mb38; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.8 Å)