9FGH

Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in large MSP2N2 nanodisc in complex with GABA in the long-lived symmetric desensitised state

Summary for 9FGH

• Entry DOI: 10.2210/pdb9fgh/pdb
• EMDB information: 50402
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... (12 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 294048.76

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the full-length alpha1beta3gamma2 GABA(A) receptor in large MSP2N2 nanodisc in complex with GABA in the long-lived symmetric desensitised state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3 Å)