8VWR
 
 | | Structure of steroid hydratase from Comamonas testosteroni | | Descriptor: | Acyl dehydratase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Schroeter, K.L, Forrester, T.J.B, Kimber, M.S, Seah, S.Y.K. | | Deposit date: | 2024-02-02 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Shy is a Proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain.
J.Biol.Chem., 2024
|
|
8VYL
 | |
8VZR
 | | Crystal structure of dehaloperoxidase A in complex with substrate 4-bromo-o-cresol | | Descriptor: | 4-bromo-2-methylphenol, DI(HYDROXYETHYL)ETHER, Dehaloperoxidase A, ... | | Authors: | Aktar, M.S, de Serrano, V.S, Ghiladi, R.A, Franzen, S. | | Deposit date: | 2024-02-12 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structural Comparison of Substrate Binding Sites in Dehaloperoxidase A and B.
Biochemistry, 2024
|
|
8W1V
 | | The beta2 adrenergic receptor bound to a bitopic ligand | | Descriptor: | (2S)-1-[(3-{1-[4-(4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butyl]-1H-1,2,3-triazol-4-yl}propyl)amino]-3-(2-propylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Endolysin, Lauryl Maltose Neopentyl Glycol, ... | | Authors: | Gaiser, B, Danielsen, M, Xu, X, Jorgensen, K, Fronik, P, Marcher-Rorsted, E, Wrobe, T, Hirata, K, Liu, X, Mathiesen, J, Pedersen, D. | | Deposit date: | 2024-02-19 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Bitopic Ligands Support the Presence of a Metastable Binding Site at the beta 2 Adrenergic Receptor.
J.Med.Chem., 2024
|
|
8W4B
 | | The sigma-1 receptor from Xenopus laevis in complex with progesterone by co-crystallization | | Descriptor: | PROGESTERONE, Sigma non-opioid intracellular receptor 1 | | Authors: | Xiao, Y, Fu, C, Sun, Z, Zhou, X. | | Deposit date: | 2023-08-23 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.152 Å) | | Cite: | Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor.
Nat Commun, 15, 2024
|
|
8W4C
 | | The sigma-1 receptor from Xenopus laevis in complex with progesterone by soaking | | Descriptor: | PROGESTERONE, Sigma non-opioid intracellular receptor 1 | | Authors: | Xiao, Y, Fu, C, Sun, Z, Zhou, X. | | Deposit date: | 2023-08-23 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.676 Å) | | Cite: | Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor.
Nat Commun, 15, 2024
|
|
8W4D
 | |
8W4E
 | |
8WCH
 | |
8WLU
 | | Cryo-EM structure of bat RsSHC014 spike glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | | Authors: | Wang, X, Qiao, S. | | Deposit date: | 2023-10-01 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Structural determinants of spike infectivity in bat SARS-like coronaviruses RsSHC014 and WIV1
J.Virol., 2024
|
|
8WLY
 | | Cryo-EM structure of bat WIV1 spike glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | | Authors: | Wang, X, Qiao, S. | | Deposit date: | 2023-10-01 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Structural determinants of spike infectivity in bat SARS-like coronaviruses RsSHC014 and WIV1
J.Virol., 2024
|
|
8WLZ
 | | Cryo-EM structure of the WIV1 S-hACE2 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | | Authors: | Wang, X, Qiao, S. | | Deposit date: | 2023-10-01 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.45 Å) | | Cite: | Structural determinants of spike infectivity in bat SARS-like coronaviruses RsSHC014 and WIV1
J.Virol., 2024
|
|
8WQ0
 | | Cryo-EM structure of WIV1 spike glycoprotein (the closed state) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Wang, X, Qiao, S. | | Deposit date: | 2023-10-10 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Structural determinants of spike infectivity in bat SARS-like coronaviruses RsSHC014 and WIV1
to be published
|
|
8WUE
 | |
8WV4
 | | C-reactive protein, pentamer | | Descriptor: | C-reactive protein(1-205), CALCIUM ION | | Authors: | Yadav, S, Vinothkumar, K.R. | | Deposit date: | 2023-10-23 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024
|
|
8WV5
 | | C-reactive protein, decamer | | Descriptor: | C-reactive protein(1-205), CALCIUM ION | | Authors: | Yadav, S, Vinothkumar, K.R. | | Deposit date: | 2023-10-23 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024
|
|
8WV6
 | | PaaZ, bifunctional enzyme | | Descriptor: | Bifunctional protein PaaZ | | Authors: | Yadav, S, Vinothkumar, K.R. | | Deposit date: | 2023-10-23 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Factors affecting macromolecule orientations in thin films formed in cryo-EM.
Acta Crystallogr D Struct Biol, 80, 2024
|
|
8WWB
 | |
8X1Z
 | | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y:DNA:E-CFCP-TP ternary complex | | Descriptor: | DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... | | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | | Deposit date: | 2023-11-09 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations.
Sci Rep, 14, 2024
|
|
8X20
 | | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:E-CFCP-TP ternary complex | | Descriptor: | DNA/RNA (38-MER), E-CFCP-triphosphate, GLYCEROL, ... | | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | | Deposit date: | 2023-11-09 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations.
Sci Rep, 14, 2024
|
|
8X21
 | | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:ETV-TP ternary complex | | Descriptor: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | | Deposit date: | 2023-11-09 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations.
Sci Rep, 14, 2024
|
|
8X22
 | | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:dGTP ternary complex | | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | | Deposit date: | 2023-11-09 | | Release date: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations.
Sci Rep, 14, 2024
|
|
8X7N
 | |
8XOL
 | | Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | | Authors: | Zhang, P.F, Liu, Z. | | Deposit date: | 2024-01-01 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
|
|
8XOM
 | | Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | | Authors: | Zhang, P.F, Liu, Z. | | Deposit date: | 2024-01-01 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
|
|
