7BCE
 
 | | Notum Fragment 718 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(4-methylpiperidin-1-yl)methyl]-1H-indole, DIMETHYL SULFOXIDE, ... | | Authors: | Zhao, Y, Jones, E.Y. | | Deposit date: | 2020-12-19 | | Release date: | 2025-10-15 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural Analysis and Development of Notum Fragment Screening Hits.
Acs Chem Neurosci, 13, 2022
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8RXM
 | | Galectin-3 in complex with thiogalactoside derivative | | Descriptor: | 5-bromanyl-3-[(2~{R},3~{R},4~{S},5~{R},6~{R})-4-[4-(4-chloranyl-1,3-thiazol-2-yl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3-methoxy-5-oxidanyl-oxan-2-yl]sulfanyl-pyridine-2-carbonitrile, CHLORIDE ION, GLYCEROL, ... | | Authors: | Hakansson, M, Diehl, C, Peterson, K, Zetterberg, F, Nilsson, U. | | Deposit date: | 2024-02-07 | | Release date: | 2025-10-15 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Galectin-3 in complex with thiogalactoside derivative
To be published
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8YY4
 | | Kinesin-14 with AlF3 bound to 13 PF Microtubule | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Shibata, S, Imasaki, T, Shigematsu, H, Hagio, H, Endow, S.A, Nitta, R. | | Deposit date: | 2024-04-03 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (4.02 Å) | | Cite: | Structural transitions in kinesin minus-end directed microtubule motility.
Biorxiv, 2024
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8YY6
 | | Structure of a murine monoclonal antibody Fab5 targeting Epstein-Barr virus gB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BALF4, Fab5 H chain, ... | | Authors: | Fang, X.Y, Sun, C, Zeng, M.S, Liu, Z. | | Deposit date: | 2024-04-03 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Chimeric Glycoprotein Nanoparticles Elicit Robust Neutralizing Antibodies Against Epstein-Barr Virus.
Adv Mater, 2025
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8Z1U
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9BDM
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9BDR
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9DKK
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9DTH
 | | Tyr-His linked F33Y CuBMb | | Descriptor: | Myoglobin, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Lu, Y, Liu, Y. | | Deposit date: | 2024-10-01 | | Release date: | 2025-10-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Post-translational Histidine-Histidine Cross-Link Enhances Enzymatic Oxygen Reduction Activity with Greater pH Adaptability.
J.Am.Chem.Soc., 2025
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9DTI
 | | F33Y CuBMb | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Myoglobin, ... | | Authors: | Lu, Y, Liu, Y. | | Deposit date: | 2024-10-01 | | Release date: | 2025-10-15 | | Method: | X-RAY DIFFRACTION (1.681 Å) | | Cite: | A Post-translational Histidine-Histidine Cross-Link Enhances Enzymatic Oxygen Reduction Activity with Greater pH Adaptability.
J.Am.Chem.Soc., 2025
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9DVB
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9DVC
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9DVD
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9DVS
 | | CryoEM structure of Syn7942 RNAP-SigA holoenzyme | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Fang, M, Gu, Y, Matyszewski, M, Leanca, M, LiWang, A, Yuzenkova, Y, Corbett, K.D, Golden, S.E. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Reconstitution of Circadian Transcription in vitro through RpaA Regulation
To Be Published
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9DVT
 | | Cryo-EM structure of RpaA bound to PkaiBC DNA and the CTD of the alpha subunit of RNAP from the cyanobacterium Synechococcus elongatus | | Descriptor: | DNA-binding dual master transcriptional regulator RpaA, DNA-directed RNA polymerase subunit alpha, Non-template DNA, ... | | Authors: | Fang, M, Gu, Y, Matyszewski, M, Leanca, M, LiWang, A, Yuzenkova, Y, Corbett, K.D, Golden, S.E. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Reconstitution of Circadian Transcription in vitro through RpaA Regulation
To Be Published
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9DVU
 | | CryoEM structure of RpaA bound to PkaiBC DNA and Syn7942 RNAP-SigA holoenzyme | | Descriptor: | DNA-binding dual master transcriptional regulator RpaA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Fang, M, Gu, Y, Matyszewski, M, Leanca, M, LiWang, A, Yuzenkova, Y, Corbett, K.D, Golden, S.E. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Reconstitution of Circadian Transcription in vitro through RpaA Regulation
To Be Published
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9DVY
 | | Human mitochondrial ClpX with endogenous substrate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit clpX-like, ... | | Authors: | Chen, W.C. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Assembly and proteolytic activation human ClpXP defined by cryo-EM
To Be Published
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9DW0
 | | Human ClpX-bound ClpP | | Descriptor: | ATP-dependent Clp protease proteolytic subunit, mitochondrial | | Authors: | Chen, W.C. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Assembly and proteolytic activation human ClpXP defined by cryo-EM
To Be Published
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9DW1
 | | Human mitochondrial ClpP protease | | Descriptor: | ATP-dependent Clp protease proteolytic subunit, mitochondrial | | Authors: | Chen, W.C. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Assembly and proteolytic activation human ClpXP defined by cryo-EM
To Be Published
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9DW3
 | | Human mitochondrial ClpP in complex with Bortezomib | | Descriptor: | ATP-dependent Clp protease proteolytic subunit, mitochondrial, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | | Authors: | Chen, W. | | Deposit date: | 2024-10-08 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Assembly and proteolytic activation human ClpXP defined by cryo-EM
To Be Published
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9DXN
 | | Structure of AcrB in the form of Native cell membrane nanoparticles (NCMNP33-50) | | Descriptor: | Multidrug efflux pump subunit AcrB | | Authors: | Guo, Y, Plutkins, S, Trinh, T.K.H, Catalano, C, Lin, Y.L, Guo, H. | | Deposit date: | 2024-10-11 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Synthesis, characterization, and application of membrane-active polymers, NCMNP33-x
To Be Published
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9E61
 | | Cryo-EM structure of Saccharomyces cerevisiae Pmt4 apo form | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Dolichyl-phosphate-mannose--protein mannosyltransferase 4 | | Authors: | Du, M, Yuan, Z, Li, H. | | Deposit date: | 2024-10-29 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Pmt4 recognizes two separate acceptor sites to O-mannosylate the S/T-rich regions of substrate proteins
To Be Published
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9E6I
 | | Cryo-EM structure of Saccharomyces cerevisiae Pmt4-Ccw5 complex | | Descriptor: | (3R)-3,31-dimethyl-7,11,15,19,23,27-hexamethylidenedotriacont-31-en-1-yl dihydrogen phosphate, Cell wall mannoprotein CIS3, Dolichyl-phosphate-mannose--protein mannosyltransferase 4 | | Authors: | Du, M, Yuan, Z, Li, H. | | Deposit date: | 2024-10-30 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Pmt4 recognizes two separate acceptor sites to O-mannosylate the S/T-rich regions of substrate proteins
To Be Published
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9E6V
 | | Cryo-EM structure of Saccharomyces cerevisiae Pmt4-Ccw5 complex | | Descriptor: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cell wall mannoprotein CIS3, Dolichyl-phosphate-mannose--protein mannosyltransferase 4, ... | | Authors: | Du, M, Yuan, Z, Li, H. | | Deposit date: | 2024-10-31 | | Release date: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Pmt4 recognizes two separate acceptor sites to O-mannosylate the S/T-rich regions of substrate proteins
To Be Published
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9E79
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