10EE
 
 | | Cannabis sativa O methyl transferase 1 | | Descriptor: | ACETATE ION, GLYCEROL, O-methyltransferase 1, ... | | Authors: | Forrester, T.J.B, Kimber, M.S. | | Deposit date: | 2026-01-15 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Cell-Free Synthesis of Cannabistilbene I: A Dual Acting Anti-Inflammatory from Cannabis sativa.
J.Nat.Prod., 2026
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10EF
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10EG
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10EH
 | | De novo assembled CBF3-CEN complex | | Descriptor: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | | Authors: | Mengqiu, J, Sue, B. | | Deposit date: | 2026-01-15 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Native yeast kinetochore structures identify an essential inner kinetochore interaction
To Be Published
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10FJ
 | | FcgRIIa in complex with IV.3 Fab | | Descriptor: | IV.3 Fab heavy chain, IV.3 Fab light chain, Low affinity immunoglobulin gamma Fc region receptor II-a | | Authors: | Coller, B.S, Wang, J.L. | | Deposit date: | 2026-01-16 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Mechanistic Basis for the Selective Recognition of the Fc gamma Receptor IIa by Monoclonal Antibody IV.3.
Biorxiv, 2026
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10PL
 | | Asymmetric architecture and adaptation of Treponema flagella | | Descriptor: | Flagellar filament outer layer protein, Flagellar filament outer layer protein FlaA, putative, ... | | Authors: | Wang, J, Kurniyati, K, Guo, W, Botting, J.M, Sindelar, C.V, Li, C, Liu, J. | | Deposit date: | 2026-01-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Asymmetric architecture and adaptation of Treponema flagella.
Nat Commun, 2026
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10PM
 | | Asymmetric architecture and adaptation of Treponema flagella | | Descriptor: | Flagellin | | Authors: | Wang, J, Kurniyati, K, Guo, W, Botting, J.M, Sindelar, C.V, Li, C, Liu, J. | | Deposit date: | 2026-01-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Asymmetric architecture and adaptation of Treponema flagella.
Nat Commun, 2026
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10PP
 | | Asymmetric architecture and adaptation of Treponema flagella | | Descriptor: | Flagellin | | Authors: | Wang, J, Kurniyati, K, Guo, W, Botting, J.M, Sindelar, C.V, Li, C, Liu, J. | | Deposit date: | 2026-01-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Asymmetric architecture and adaptation of Treponema flagella.
Nat Commun, 2026
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10SE
 | | The CryoEM structure of T8 nanofiber | | Descriptor: | OCTANOIC ACID (CAPRYLIC ACID), T8 nanofiber | | Authors: | Zhang, H, Yang, Y. | | Deposit date: | 2026-02-05 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (2.41 Å) | | Cite: | Tailoring Avidity through Morphology: Structure-Avidity Relationship in CD38-Binding Nanofiber Radiotracers.
Acs Appl Bio Mater, 9, 2026
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10SF
 | | The CryoEM structure of T10 type1 nanofiber | | Descriptor: | DECANOIC ACID, Type10 type 1 nanofiber | | Authors: | Zhang, H, Yang, Y. | | Deposit date: | 2026-02-05 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Tailoring Avidity through Morphology: Structure-Avidity Relationship in CD38-Binding Nanofiber Radiotracers.
Acs Appl Bio Mater, 9, 2026
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10YS
 | | Structure of Cbl-B bound to compound 33 | | Descriptor: | 1,2-ETHANEDIOL, 2-{3-[(1r,3r)-3-methoxy-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl}-6-{[(1-methylcyclobutyl)amino]methyl}-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, DIMETHYL SULFOXIDE, ... | | Authors: | Murray, J, Yu, C, Hsu, P.L. | | Deposit date: | 2026-02-12 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Optimization Leading to a Potent and Selective Cbl‐b Inactive-State Inhibitor That Demonstrated In Vivo Efficacy.
Acs Med.Chem.Lett., 17, 2026
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10ZF
 | | Structure of c-Cbl bound to compound 33 | | Descriptor: | 2-{3-[(1r,3r)-3-methoxy-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl]phenyl}-6-{[(1-methylcyclobutyl)amino]methyl}-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, Glutathione S-transferase class-mu 26 kDa isozyme,E3 ubiquitin-protein ligase CBL, MAGNESIUM ION, ... | | Authors: | Murray, J, Yu, C, Hsu, P.L. | | Deposit date: | 2026-02-12 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Optimization Leading to a Potent and Selective Cbl‐b Inactive-State Inhibitor That Demonstrated In Vivo Efficacy.
Acs Med.Chem.Lett., 17, 2026
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10ZJ
 | | Structure of Cbl-B bound to compound 8 | | Descriptor: | 1,2-ETHANEDIOL, 6-{[(3,3-difluoropropyl)amino]methyl}-2-(3-{3-[(R)-fluoro(4-methyl-4H-1,2,4-triazol-3-yl)methyl]oxetan-3-yl}phenyl)-4-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one, E3 ubiquitin-protein ligase CBL-B, ... | | Authors: | Murray, J, Yu, C, Hsu, P.L. | | Deposit date: | 2026-02-12 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Optimization and In Vivo Characterization of a Series of Cbl‐b Inactive-State Inhibitors.
Acs Med.Chem.Lett., 17, 2026
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10ZY
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10ZZ
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11AA
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11LH
 | | OgOGA IN COMPLEX WITH LIGAND 7 | | Descriptor: | N~4~-butyl-N~2~-(2,6-dichlorophenyl)pyridine-2,4-diamine, Protein O-GlcNAcase | | Authors: | Shaffer, P.L. | | Deposit date: | 2026-03-03 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Discovery of 5‐Azaindole Inhibitors of O‐GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies.
Acs Med.Chem.Lett., 17, 2026
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11LI
 | | OgOGA IN COMPLEX WITH LIGAND 24 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, N,N-dimethyl-2-(4-{[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino}-1H-pyrrolo[3,2-c]pyridin-1-yl)acetamide, ... | | Authors: | Shaffer, P.L. | | Deposit date: | 2026-03-03 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Discovery of 5‐Azaindole Inhibitors of O‐GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies.
Acs Med.Chem.Lett., 17, 2026
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11LJ
 | | Human OGA IN COMPLEX WITH LIGAND 24 | | Descriptor: | CALCIUM ION, N,N-dimethyl-2-(4-{[4-methyl-2-(propan-2-yl)pyridin-3-yl]amino}-1H-pyrrolo[3,2-c]pyridin-1-yl)acetamide, Protein O-GlcNAcase 535-704 Peptide, ... | | Authors: | Shaffer, P.L, Cedervall, P. | | Deposit date: | 2026-03-03 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (2.325 Å) | | Cite: | Discovery of 5‐Azaindole Inhibitors of O‐GlcNAcase for the Treatment of Alzheimer's Disease and Related Tauopathies.
Acs Med.Chem.Lett., 17, 2026
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11OK
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12AJ
 | | Citrobacter rodentium contact dependent growth inhibition (CDI) toxin (CdiA-CT) in complex with E. coli GyrB | | Descriptor: | Contact-dependent inhibitor A, DNA gyrase subunit B, GLYCEROL | | Authors: | Cuthbert, B.J, Hardy, C.D, Kennady, J.R, Goulding, C.W, Hayes, C.S, Nhan, D.Q. | | Deposit date: | 2026-03-23 | | Release date: | 2026-07-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains
To Be Published
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12BM
 | | Human 19S proteasome bound to TXNL1 PITH domain state 2 | | Descriptor: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... | | Authors: | Chen, X, Negi, H, Walters, K.J. | | Deposit date: | 2026-03-25 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Structures of dynamic interactors at native proteasomes by PhIX-MS and cryo-electron microscopy
To Be Published
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12EB
 | | Half-translocated RNA polymerase elemental paused elongation complex, swiveled with ppGpp (ePEC swiveled + ppGpp) | | Descriptor: | CHAPSO, DNA non-template strand, DNA template strand, ... | | Authors: | Mueller, A.U, Darst, S.A, Landick, R. | | Deposit date: | 2026-03-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | ppGpp regulates transcription elongation via direct and indirect inputs to RNA polymerase pausing and nucleotide addition.
Biorxiv, 2026
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12EC
 | | Half-translocated RNA polymerase elemental paused elongation complex, swiveled (ePEC swiveled) | | Descriptor: | CHAPSO, DNA non-template strand, DNA template strand, ... | | Authors: | Mueller, A.U, Darst, S.A, Landick, R. | | Deposit date: | 2026-03-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | ppGpp regulates transcription elongation via direct and indirect inputs to RNA polymerase pausing and nucleotide addition.
Biorxiv, 2026
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12ED
 | | Pre-translocated RNA polymerase elemental paused elongation complex, TL open with ppGpp (ePEC open + ppGpp) | | Descriptor: | CHAPSO, DNA non-template strand, DNA template strand, ... | | Authors: | Mueller, A.U, Darst, S.A, Landick, R. | | Deposit date: | 2026-03-30 | | Release date: | 2026-07-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | ppGpp regulates transcription elongation via direct and indirect inputs to RNA polymerase pausing and nucleotide addition.
Biorxiv, 2026
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