8ZNN

X-ray structure of human PPAR delta ligand binding domain in complex with a synthetic agonist 16a

This is a non-PDB format compatible entry.

Summary for 8ZNN

• Entry DOI: 10.2210/pdb8znn/pdb
• Descriptor: Peroxisome proliferator-activated receptor delta, 6-[2-[[2-[4-(trifluoromethyloxy)phenyl]benzimidazol-1-yl]methyl]phenoxy]hexanoic acid (3 entities in total)
• Functional Keywords: agonist, ppar, nuclear protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 31387.43

Authors

Dai, L.,Sun, H.,Feng, Z. (deposition date: 2024-05-27, release date: 2025-12-24)

• Primary citation: Feng, Z.,Sun, H.,Dai, L.; Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPARd Agonists for the Treatment of Renal Fibrosis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)