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7NFX
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BU of 7nfx by Molmil
Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Jomaa, A, Lee, J.H, Shan, S, Ban, N.
Deposit date:2021-02-08
Release date:2021-06-02
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
Sci Adv, 7, 2021
7NG8
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BU of 7ng8 by Molmil
Trimeric efflux pump Klebsiella TolC in complex with KlebC
Descriptor: Klebicin C activity, Outer membrane channel protein
Authors:Webby, M.N, Housden, N.G, Kleanthous, C.
Deposit date:2021-02-08
Release date:2021-06-30
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Toxin import through the antibiotic efflux channel TolC.
Nat Commun, 12, 2021
7NH3
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BU of 7nh3 by Molmil
Nematocida Huwe1 in open conformation.
Descriptor: E3 ubiquitin-protein ligase HUWE1
Authors:Petrova, O, Grishkovskaya, I, Grabarczyk, D.B, Kessler, D, Haselbach, D, Clausen, T.
Deposit date:2021-02-09
Release date:2022-03-02
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (6.37 Å)
Cite:Crystal structure of HUWE1: One ring to ubiquitinate them all
To Be Published
7NH6
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BU of 7nh6 by Molmil
Crystal structure of human carbonic anhydrase II with 3-(3-((1-(2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-1H-1,2,3-triazol-4-yl)methyl)ureido)benzenesulfonamide
Descriptor: 3-(3-((1-(2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-1H-1,2,3-triazol-4-yl)methyl)ureido)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Angeli, A, Ferraroni, M.
Deposit date:2021-02-10
Release date:2022-02-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
J.Med.Chem., 64, 2021
7NH8
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BU of 7nh8 by Molmil
Crystal structure of human carbonic anhydrase II with N-((1-(6-((3aR,7R,7aS)-7-hydroxy-2,2-dimethyltetrahydro-[1,3]dioxolo[4,5-c]pyridin-5(4H)-yl)hexyl)-1H-1,2,3-triazol-4-yl)methyl)-4-sulfamoylbenzamide
Descriptor: Carbonic anhydrase 2, N-((1-(6-((3aR,7R,7aS)-7-hydroxy-2,2-dimethyltetrahydro-[1,3]dioxolo[4,5-c]pyridin-5(4H)-yl)hexyl)-1H-1,2,3-triazol-4-yl)methyl)-4-sulfamoylbenzamide, ZINC ION
Authors:Angeli, A, Ferraroni, M.
Deposit date:2021-02-10
Release date:2022-02-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.369 Å)
Cite:Synthesis of Azasugar-Sulfonamide conjugates and their Evaluation as Inhibitors of Carbonic Anhydrases: the Azasugar Approach to Selectivity
Eur.J.Org.Chem., 2021
7NHK
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BU of 7nhk by Molmil
LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Crowe-McAuliffe, C, Kasari, M, Hauryliuk, V.H, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NHL
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BU of 7nhl by Molmil
VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NHM
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BU of 7nhm by Molmil
70S ribosome from Staphylococcus aureus
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Murina, V, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NHN
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BU of 7nhn by Molmil
VgaL, an antibiotic resistance ABCF, in complex with 70S ribosome from Listeria monocytogenes
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Crowe-McAuliffe, C, Turnbull, K.J, Hauryliuk, V, Wilson, D.N.
Deposit date:2021-02-10
Release date:2021-05-05
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Nat Commun, 12, 2021
7NKT
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BU of 7nkt by Molmil
RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ...
Authors:Ostertag, E, Zocher, G, Stehle, T.
Deposit date:2021-02-18
Release date:2021-05-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:NeutrobodyPlex-monitoring SARS-CoV-2 neutralizing immune responses using nanobodies.
Embo Rep., 22, 2021
7NLV
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BU of 7nlv by Molmil
WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE II
Descriptor: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, Streptavidin
Authors:Nodling, A.R, Santi, N, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y.
Deposit date:2021-02-22
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:The role of streptavidin and its variants in catalysis by biotinylated secondary amines.
Org.Biomol.Chem., 19, 2021
7NM7
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BU of 7nm7 by Molmil
The crystal structure of the antimycin pathway standalone ketoreductase, AntM
Descriptor: Antimycin pathway standalone ketoreductase enzyme, AntM
Authors:Fazal, A, Hemsworth, G.R, Webb, M.E, Seipke, R.F.
Deposit date:2021-02-23
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Standalone beta-Ketoreductase Acts Concomitantly with Biosynthesis of the Antimycin Scaffold.
Acs Chem.Biol., 16, 2021
7NM8
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BU of 7nm8 by Molmil
The crystal structure of the antimycin pathway standalone ketoreductase, AntM, in complex with NADPH
Descriptor: Antimycin pathway standalone ketoreductase, AntM, GLYCEROL, ...
Authors:Fazal, A, Hemsworth, G.R, Webb, M.E, Seipke, R.F.
Deposit date:2021-02-23
Release date:2021-06-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Standalone beta-Ketoreductase Acts Concomitantly with Biosynthesis of the Antimycin Scaffold.
Acs Chem.Biol., 16, 2021
7NMC
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BU of 7nmc by Molmil
Crystal structure of beta-2-microglobulin D76E mutant
Descriptor: Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMO
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BU of 7nmo by Molmil
Crystal structure of beta-2-microglobulin D76A mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMR
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BU of 7nmr by Molmil
Crystal structure of beta-2-microglobulin D76S mutant
Descriptor: Beta-2-microglobulin, GLYCEROL
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMT
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BU of 7nmt by Molmil
Crystal structure of beta-2-microglobulin D76G mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMU
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BU of 7nmu by Molmil
Crystal structure of human platelet glycoprotein VI in complex with an inhibitory nanobody.
Descriptor: CALCIUM ION, Nanobody 2, Platelet glycoprotein VI
Authors:Slater, A, Jonas, E, Watson, S.P.
Deposit date:2021-02-23
Release date:2021-03-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer.
Blood, 137, 2021
7NMV
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BU of 7nmv by Molmil
Crystal structure of beta-2-microglobulin D76Q mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMY
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BU of 7nmy by Molmil
Crystal structure of beta-2-microglobulin D76Y mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-23
Release date:2022-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMZ
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BU of 7nmz by Molmil
Structure of 14-3-3 eta in complex with Nedd4-2(335-455) containing two 14-3-3 binding motifs Ser342 and Ser448
Descriptor: 14-3-3 protein eta, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Obsil, T, Obsilova, V.
Deposit date:2021-02-23
Release date:2021-07-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
7NN5
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BU of 7nn5 by Molmil
Crystal structure of beta-2-microglobulin D76K mutant
Descriptor: Beta-2-microglobulin
Authors:Guthertz, N.
Deposit date:2021-02-24
Release date:2022-08-03
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.242 Å)
Cite:The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NP7
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BU of 7np7 by Molmil
Structure of an intact ESX-5 inner membrane complex, Composite C1 model
Descriptor: ESX-5 secretion system ATPase EccB5, ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5, ...
Authors:Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C.
Deposit date:2021-02-26
Release date:2021-06-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Structure and dynamics of a mycobacterial type VII secretion system.
Nature, 593, 2021
7NPM
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BU of 7npm by Molmil
X-ray structure of the adduct formed upon reaction of oxaliplatin with human angiogenin
Descriptor: Angiogenin, D(-)-TARTARIC ACID, PLATINUM (II) ION
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-02-27
Release date:2022-03-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Oxaliplatin inhibits angiogenin proliferative and cell migration effects in prostate cancer cells.
J.Inorg.Biochem., 226, 2022
7NPN
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BU of 7npn by Molmil
B-brick bare in 5 mM Mg2+
Descriptor: SCAFFOLD STRAND, STAPLE STRAND
Authors:Bertosin, E, Stoemmer, P, Feigl, E, Wenig, M, Honemann, M, Dietz, H.
Deposit date:2021-02-27
Release date:2021-03-31
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (10.38 Å)
Cite:Cryo-Electron Microscopy and Mass Analysis of Oligolysine-Coated DNA Nanostructures.
Acs Nano, 15, 2021

238582

数据于2025-07-09公开中

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