6WS0
 
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6WS5
 | | Rational drug design of phenazopyridine derivatives as novel inhibitors of Rev1-CT | | 分子名称: | 3-[(Z)-(2,3-difluorophenyl)diazenyl]pyridine-2,6-diamine, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ... | | 著者 | McPherson, K.S, Korzhnev, D.M. | | 登録日 | 2020-04-30 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.472 Å) | | 主引用文献 | Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
Chemmedchem, 16, 2021
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6WXE
 | | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Upright conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | | 著者 | Herrmann, T, Harrison, S.C, Jenni, S. | | 登録日 | 2020-05-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Functional refolding of the penetration protein on a non-enveloped virus.
Nature, 590, 2021
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6WXF
 | | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Intermediate conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | | 著者 | Herrmann, T, Harrison, S.C, Jenni, S. | | 登録日 | 2020-05-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Functional refolding of the penetration protein on a non-enveloped virus.
Nature, 590, 2021
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6WXG
 | | Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Reversed conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | | 著者 | Herrmann, T, Harrison, S.C, Jenni, S. | | 登録日 | 2020-05-10 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Functional refolding of the penetration protein on a non-enveloped virus.
Nature, 590, 2021
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6X02
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6X03
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6X2I
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6X2K
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6X32
 | | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 1 and 2, closed) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X33
 | | Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X35
 | | Pig R615C RyR1 in complex with CaM, EGTA (class 1, open) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ... | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X36
 | | Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed) | | 分子名称: | Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor | | 著者 | Woll, K.W, Haji-Ghassemi, O, Van Petegem, F. | | 登録日 | 2020-05-21 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
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6X5I
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6X62
 | | Legionella pneumophila Dot T4SS OMC | | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | | 登録日 | 2020-05-27 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex.
Elife, 9, 2020
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6X63
 | | Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR | | 分子名称: | HIV-1 capsid protein | | 著者 | Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T. | | 登録日 | 2020-05-27 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR.
Nat.Struct.Mol.Biol., 27, 2020
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6X64
 | | Legionella pneumophila Dot T4SS PR | | 分子名称: | Type IV secretion system unknown protein fragment | | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | | 登録日 | 2020-05-27 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex.
Elife, 9, 2020
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6X65
 | | Legionella pneumophila Dot/Icm T4SS | | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | | 登録日 | 2020-05-27 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex.
Elife, 9, 2020
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6X66
 | | Legionella pneumophila dDot T4SS OMC | | 分子名称: | DotC, DotD, Inner membrane lipoprotein YiaD, ... | | 著者 | Durie, C.L, Sheedlo, M.J, Chung, J.M, Byrne, B.G, Su, M, Knight, T, Swanson, M.S, Lacy, D.B, Ohi, M.D. | | 登録日 | 2020-05-27 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex.
Elife, 9, 2020
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6X6G
 | | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with droperidol | | 分子名称: | 3-[1-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-2,3,4,5-tetrahydropyridin-4-yl]-1~{H}-benzimidazol-2-one, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | 著者 | Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | | 登録日 | 2020-05-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance
Rsc Med Chem, 12, 2021
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6X6H
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6X6I
 | | Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT543 | | 分子名称: | 4-(4-benzyl-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. | | 登録日 | 2020-05-28 | | 公開日 | 2021-06-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from Mycobacterium tuberculosis to overcome kanamycin resistance
Rsc Med Chem, 12, 2021
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6X6J
 | | Cryo-EM Structure of CagX and CagY within the Helicobacter pylori PR | | 分子名称: | Cag pathogenicity island protein (Cag7), Cag pathogenicity island protein (Cag8) | | 著者 | Sheedlo, M.J, Chung, J.M, Sawhney, N, Durie, C.L, Cover, T.L, Ohi, M.D, Lacy, D.B. | | 登録日 | 2020-05-28 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex.
Elife, 9, 2020
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6X6K
 | | Cryo-EM Structure of the Helicobacter pylori dCag3 OMC | | 分子名称: | Cag pathogenicity island protein, Cag pathogenicity island protein (Cag7), Type IV secretion system apparatus protein CagX | | 著者 | Sheedlo, M.J, Chung, J.M, Sawhney, N, Durie, C.L, Cover, T.L, Ohi, M.D, Lacy, D.B. | | 登録日 | 2020-05-28 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex.
Elife, 9, 2020
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6X6L
 | | Cryo-EM Structure of CagX and CagY within the dCag3 Helicobacter pylori PR | | 分子名称: | Cag pathogenicity island protein (Cag7), Cag pathogenicity island protein (Cag8) | | 著者 | Sheedlo, M.J, Chung, J.M, Sawhney, N, Durie, C.L, Cover, T.L, Ohi, M.D, Lacy, D.B. | | 登録日 | 2020-05-28 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex.
Elife, 9, 2020
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