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PDB形式変換不可の PDB エントリー
8UXF
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Structure of PKA phosphorylated human RyR2-R420W in the primed state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXG
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BU of 8uxg by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
分子名称: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXH
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BU of 8uxh by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXI
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BU of 8uxi by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXL
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BU of 8uxl by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Miotto, M.C, Marks, A.R.
登録日2023-11-09
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UZT
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BU of 8uzt by Molmil
Mitochondrial single-stranded binding protein bound to DNA
分子名称: GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ...
著者Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C.
登録日2023-11-16
公開日2024-08-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma.
Nucleic Acids Res., 2024
8V3D
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BU of 8v3d by Molmil
AgamOR28 structure bound to 2,4,5-trimethylthiazole
分子名称: 2,4,5-trimethyl-1,3-thiazole, OR28, Odorant receptor Orco
著者Zhao, J, del Marmol, J.
登録日2023-11-27
公開日2024-06-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of odor sensing by insect heteromeric odorant receptors.
Science, 384, 2024
8V3L
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Microtubule inner proteins in the 48-nm doublet microtubule from the proximal region of Tetrahymena thermophila strain K40R
分子名称: BMIP1, CCDC81B
著者Legal, T, Bui, K.H.
登録日2023-11-28
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献48-nm doublet microtubule from the proximal region of Tetrahymena thermophila strain K40R
To Be Published
8V3N
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CCP5 in complex with Glu-P-Glu transition state analog
分子名称: (2S)-2-{[(S)-[(3S)-3-acetamido-4-(ethylamino)-4-oxobutyl](hydroxy)phosphoryl]methyl}pentanedioic acid, Cytosolic carboxypeptidase-like protein 5, D-MALATE, ...
著者Chen, J, Zehr, E.A, Gruschus, J.M, Szyk, A, Liu, Y, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
登録日2023-11-28
公開日2024-07-17
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Nature, 631, 2024
8V3T
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CryoEM Structure of Diffocin - precontracted - Collar
分子名称: Collar (CD1362), Sheath (CD1363), Tube (CD1364)
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V3W
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CryoEM Structure of Diffocin - precontracted - Baseplate - focused refinement on triplex region
分子名称: Hub-Hydrolase (CD1368), Sheath (CD1363), Sheath initiator (CD1370), ...
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V3Z
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BU of 8v3z by Molmil
CryoEM Structure of Diffocin - postcontracted - Collar - transitional state
分子名称: Collar (CD1362), Sheath (CD1363), Tube (CD1364)
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V40
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CryoEM Structure of Diffocin - postcontracted - Collar - final state
分子名称: Collar (CD1362), Sheath (CD1363), Tube (CD1364)
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V41
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BU of 8v41 by Molmil
CryoEM Structure of Diffocin - postcontracted - Baseplate - transitional state
分子名称: Sheath (CD1363), Sheath initiator (CD1370), TRI-1 (CD1372), ...
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V43
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BU of 8v43 by Molmil
CryoEM Structure of Diffocin - postcontracted - Baseplate - final state
分子名称: Sheath (CD1363), Sheath initiator (CD1370), TRI-1 (CD1372), ...
著者Cai, X.Y, He, Y, Zhou, Z.H.
登録日2023-11-28
公開日2024-08-28
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Atomic structures of a bacteriocin targeting Gram-positive bacteria.
Nat Commun, 15, 2024
8V4X
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BU of 8v4x by Molmil
Structure of MALT1 in complex with an allosteric inhibitor
分子名称: Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea
著者Judge, R.A, Pappano, W.N.
登録日2023-11-29
公開日2024-05-01
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma.
Mol.Cancer Ther., 23, 2024
8V5A
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BU of 8v5a by Molmil
Prefusion-stabilized Respirovirus type 3 Fusion protein
分子名称: Camelid nanobody 4C06, Fusion glycoprotein F0
著者Johnson, N.V, McLellan, J.S.
登録日2023-11-30
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein.
Nat Commun, 15, 2024
8V6P
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Proteus vulgaris tryptophan indole-lyase complexed with 7-aza-L-tryptophan
分子名称: (2E)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid, (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-L-alanine, DIMETHYL SULFOXIDE, ...
著者Phillips, R.S.
登録日2023-12-02
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Proteus vulgaris tryptophan indole-lyase complexed with L-alanine
To Be Published
8V7X
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Cryo-EM structure of TTMV-LY1 anellovirus virus-like particle expressed in HEK293
分子名称: Capsid protein
著者Rajendra, B, Swanson, K.
登録日2023-12-04
公開日2024-09-04
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of anellovirus-like particles reveal a mechanism for immune evasion.
Nat Commun, 15, 2024
8V83
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60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V84
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60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V87
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60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map)
分子名称: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
著者Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P.
登録日2023-12-04
公開日2024-05-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Nat Commun, 15, 2024
8V8Z
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Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329
分子名称: Apolipoprotein(a), muvalaplin
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-12-06
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024
8V9B
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Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732
分子名称: (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ...
著者Hendle, J, Weichert, K, Sauder, J.M.
登録日2023-12-07
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Nature, 629, 2024

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件を2024-09-11に公開中

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