7OIZ
 
 | | Cryo-EM structure of 70S ribosome stalled with TnaC peptide | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | | 登録日 | 2021-05-13 | | 公開日 | 2021-09-15 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
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7OJ0
 | | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | | 登録日 | 2021-05-13 | | 公開日 | 2021-09-15 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
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7OJ7
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7OJF
 | | CRYO-EM STRUCTURE OF SLYB13-BAMA FROM ESCHERICHIA COLI. | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | 著者 | Nguyen, V.S, Remaut, H. | | 登録日 | 2021-05-14 | | 公開日 | 2022-07-27 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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7OJG
 | | CRYO-EM STRUCTURE OF UNDECAMERIC SLYB FROM ESCHERICHIA COLI K12 | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(~{E},3~{R})-3-dodecanoyloxytetradec-5-enoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(~{E},3~{R})-3-oxidanyltetradec-11-enoyl]amino]-4-[(~{E},3~{R})-3-oxidanyltetradec-5-enoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(~{E},3~{R})-3-tetradecanoyloxytetradec-7-enoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, GLYCEROL, ... | | 著者 | Nguyen, V.S, Remaut, H. | | 登録日 | 2021-05-14 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains
Nature, 2023
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7OJM
 | | CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) CATALYTICALLY INACTIVE H251A VARIANT COMPLEXED WITH 2-METHYL-QUINOLIN-4(1H)-ONE UNDER NORMOXIC CONDITIONS | | 分子名称: | 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, GLYCEROL, ... | | 著者 | Bui, S, Steiner, R.A. | | 登録日 | 2021-05-16 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold.
Chem Sci, 14, 2023
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7OJO
 | | Tankyrase 2 in complex with two small molecule fragments | | 分子名称: | 4-acetamido-~{N}-(2-methoxyphenyl)benzamide, Poly [ADP-ribose] polymerase tankyrase-2, SULFATE ION, ... | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-05-17 | | 公開日 | 2022-06-01 | | 最終更新日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Deconstruction of Dual-Site Tankyrase Inhibitors Provides Insights into Binding Energetics and Suggests Critical Hotspots for Ligand Optimization.
J.Med.Chem., 68, 2025
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7OK6
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7OK8
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7OKO
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7OKR
 | | Catalytic domain from the Aliivibrio salmonicida lytic polysaccharide monooxygenase AsLPMO10B | | 分子名称: | COPPER (II) ION, Chitinase B, DI(HYDROXYETHYL)ETHER | | 著者 | Cordara, G, Leitl, K.D, Loose, J.S.M, Vaaje-Kolstad, G, Krengel, U. | | 登録日 | 2021-05-18 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Chitinolytic enzymes contribute to the pathogenicity of Aliivibrio salmonicida LFI1238 in the invasive phase of cold-water vibriosis.
Bmc Microbiol., 22, 2022
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7OKZ
 | | CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) CATALYTICALLY INACTIVE H251A VARIANT COMPLEXED WITH 2-METHYL- QUINOLIN-4(1H)-ONE UNDER HYPEROXIC CONDITIONS | | 分子名称: | 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, D(-)-TARTARIC ACID, ... | | 著者 | Bui, S, Steiner, R.A. | | 登録日 | 2021-05-18 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold.
Chem Sci, 14, 2023
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7OLC
 | | Thermophilic eukaryotic 80S ribosome at idle POST state | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2021-05-19 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7OLD
 | | Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state | | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | | 著者 | Kisonaite, M, Wild, K, Sinning, I. | | 登録日 | 2021-05-19 | | 公開日 | 2022-01-26 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation.
Nat Commun, 13, 2022
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7OLJ
 | | Tankyrase 2 in complex with an inhibitor (OUL219) | | 分子名称: | 8-propan-2-yloxy-4~{H}-thieno[2,3-c]isoquinolin-5-one, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-05-20 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Bioorg.Med.Chem., 52, 2021
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7OLN
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7OLU
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7OLW
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7OM1
 | | Tankyrase 2 in complex with an inhibitor (OUL220) | | 分子名称: | 8-methoxy-4~{H}-thieno[2,3-c]isoquinolin-5-one, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-05-21 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Bioorg.Med.Chem., 52, 2021
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7OMC
 | | Tankyrase 2 in complex with an inhibitor (OUL228) | | 分子名称: | 8-propan-2-yloxy-4~{H}-thieno[2,3-c]isoquinolin-5-one, GLYCEROL, Poly [ADP-ribose] polymerase tankyrase-2, ... | | 著者 | Sowa, S.T, Lehtio, L. | | 登録日 | 2021-05-21 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs.
Bioorg.Med.Chem., 52, 2021
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7OMI
 | | Bs164 in complex with mannocyclophellitol epoxide | | 分子名称: | (1R,2S,4S,5R)-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Armstrong, Z, Mcgregor, N, Davies, G. | | 登録日 | 2021-05-24 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Synthesis of broad-specificity activity-based probes for exo -beta-mannosidases.
Org.Biomol.Chem., 20, 2022
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7OMS
 | | Bs164 in complex with mannocyclophellitol aziridine | | 分子名称: | (1~{R},2~{R},3~{S},4~{R},5~{R},6~{R})-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | McGregor, N, Beenakker, T, Kuo, C.L, Wong, C.S, Offren, W.A, Armstrong, Z, Codee, J.D.C, Aerts, J.M.F.G, Florea, B.I, Overkleeft, H, Davies, G.J. | | 登録日 | 2021-05-24 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Synthesis of broad-specificity activity-based probes for exo -beta-mannosidases.
Org.Biomol.Chem., 20, 2022
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7OMU
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7OMV
 | | Thermus sp. 2.9 DarT | | 分子名称: | CHLORIDE ION, DarT domain-containing protein, THIOCYANATE ION | | 著者 | Schuller, M, Ariza, A. | | 登録日 | 2021-05-24 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | Molecular basis for DarT ADP-ribosylation of a DNA base.
Nature, 596, 2021
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7OMW
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