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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

An explanation article covering one of the proteins of this virus is available on the "Molecules of the Month" page below:

The tab "All entries" contains all PDB IDs, in case you want to check all independent entries, including group depositions by the same authors. The "Repr. entries" tab contains only representative PDB entries with the highest resolution, excluding duplicate entries with 100% amino acid sequence identitiy, even if they contain a different ligand. Finally, the "Latest entries" tab contains the latest entries released this week.

Created: 2020-10-28 (last edited: more than 1 year ago)2022-09-02
All entries (4476)Repr. entries (1994)Latest entries (17)
7YQX
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SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YQY
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SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YR0
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SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (interface)
Descriptor: Heavy chain of S309, IGK@ protein, Spike protein S1, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YR1
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SARS-CoV-2 BA.2.75 S Trimer in complex with XG2v024
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YR2
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SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
7YR3
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SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Wang, L.
Deposit date:2022-08-08
Release date:2022-10-19
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75.
Cell Host Microbe, 30, 2022
8D8Q
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SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ...
Authors:Du, J, Cui, J, Pallesen, J.
Deposit date:2022-06-08
Release date:2022-10-19
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
8D8R
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SARS-CoV-2 Spike RBD in complex with DMAb 2196
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ...
Authors:Du, J, Cui, J, Pallesen, J.
Deposit date:2022-06-08
Release date:2022-10-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun, 13, 2022
7WB5
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local structure of hu33 and spike
Descriptor: Surface glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hu33 heavy chain, ...
Authors:Pulan, L.
Deposit date:2021-12-15
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants.
Signal Transduct Target Ther, 7, 2022
7ZIT
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14-3-3 in complex with SARS-COV2 N phospho-peptide
Descriptor: 14-3-3 protein zeta/delta, ACETATE ION, BENZOIC ACID, ...
Authors:Eisenreichova, A, Boura, E.
Deposit date:2022-04-08
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins.
J.Struct.Biol., 214, 2022
8ERQ
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SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8ERR
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BU of 8err by Molmil
SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8GS6
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Structure of the SARS-CoV-2 BA.2.75 spike glycoprotein (closed state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Anraku, Y, Tabata-Sasaki, K, Kita, S, Fukuhara, H, Maenaka, K, Hashiguchi, T.
Deposit date:2022-09-05
Release date:2022-10-26
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant.
Cell Host Microbe, 30, 2022
7WSH
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Cryo-EM structure of SARS-CoV-2 spike receptor-binding domain in complex with sea lion ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ...
Authors:Li, S, Han, P, Qi, J.
Deposit date:2022-01-29
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals.
Natl Sci Rev, 9, 2022
7X26
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S41 neutralizing antibody Fab(MERS-CoV)
Descriptor: Spike glycoprotein, antibody S41 heavy chain, antibody S41 light chain
Authors:Zeng, J.W, Zhang, S.Y, Wang, X.W.
Deposit date:2022-02-25
Release date:2022-11-09
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.685 Å)
Cite:Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein.
Front Microbiol, 13, 2022
7X2A
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MERS-CoV spike complex with S41 neutralizing antibody Fab Class1 (1u2d RBD with 1Fab)
Descriptor: MERS-CoV Spike glycoprotein, antibody S41 heavy chain, antibody S41 light chain
Authors:Zeng, J.W, Zhang, S.Y, Zhou, H.X, Wang, X.W.
Deposit date:2022-02-25
Release date:2022-11-09
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (2.49 Å)
Cite:Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein.
Front Microbiol, 13, 2022
7ZR2
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BU of 7zr2 by Molmil
Crystal structure of a chimeric protein mimic of SARS-CoV-2 Spike HR1 in complex with HR2
Descriptor: Spike protein S2', Spike protein S2',Chimeric protein mimic of SARS-CoV-2 Spike HR1
Authors:Camara-Artigas, A, Gavira, J.A, Cano-Munoz, M, Polo-Megias, D, Conejero-Lara, F.
Deposit date:2022-05-03
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity.
Int.J.Biol.Macromol., 222, 2022
7Q3Q
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Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobody VHH-12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Fernandez, I, Pederzoli, R, Rey, F.A.
Deposit date:2021-10-28
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:NANOBODIES AGAINST SARS-COV-2 NEUTRALIZE VARIANTS OF CONCERN AND EXPLORE CONFORMATIONAL DIFFERENCES ON THE SPIKE PROTEIN
To Be Published
7Q3R
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Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobodies VHH-F04 and VHH-G09
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Spike glycoprotein, ...
Authors:Fernandez, I, Pederzoli, R, Rey, F.A.
Deposit date:2021-10-28
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:NANOBODIES AGAINST SARS-COV-2 NEUTRALIZE VARIANTS OF CONCERN AND EXPLORE CONFORMATIONAL DIFFERENCES ON THE SPIKE PROTEIN
To Be Published
7SJ0
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Antibody A7V3 bound to N-terminal domain of the spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, A7V3 Fab heavy chain, A7V3 Fab light chain, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2021-10-15
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Antibody A7V3 bound to N-terminal domain of the spike
To Be Published
8EYJ
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Crystal Structure of uncleaved SARS-CoV-2 Main Protease C145S mutant in complex with Nirmatrelvir
Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5
Authors:Noske, G.D, Godoy, A.S, Oliva, G.
Deposit date:2022-10-27
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.738 Å)
Cite:An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition.
Nat Commun, 14, 2023
7S83
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Crystal structure of SARS CoV-2 Spike Receptor Binding Domain in complex with shark neutralizing VNARs ShAb01 and ShAb02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ShAb01 VNAR, ...
Authors:Chen, W.-H, Hajduczki, A, Dooley, H.M, Joyce, M.G.
Deposit date:2021-09-17
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity.
Nat Commun, 14, 2023
7SIS
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BU of 7sis by Molmil
SARS-CoV-2 Spike-derived peptide S976-984 (VLNDILSRL) presented by HLA-A*02:01
Descriptor: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-10-14
Release date:2022-11-23
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific
Curr Res Struct Biol, 2024
7SWW
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BU of 7sww by Molmil
SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published
7SWX
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SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-57 (three down conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS2-57 Fv heavy chain, ...
Authors:Adams, L.J, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Deposit date:2021-11-21
Release date:2022-11-23
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:A protective antibody targeting the N-terminal domain of SARS-CoV-2 spike recognizes most emerging variants
To Be Published

223790

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