7HQP
 
 | |
9ECZ
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with human neutralizing antibody WRAIR-2008 (focused refinement of NTD and WRAIR-2008) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Jensen, J.L, Thomas, P.V, Joyce, M.G. | | Deposit date: | 2024-11-15 | | Release date: | 2025-08-20 | | Last modified: | 2025-10-22 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | First-generation N-terminal domain supersite public antibodies retain activity against Omicron-derived lineages and protect mice against Omicron BA.5 challenge.
Mbio, 16, 2025
|
|
9FWK
 | | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00123 | | Descriptor: | (4R)-4-pyridin-4-ylpyrrolidin-2-one, (4S)-4-pyridin-4-ylpyrrolidin-2-one, DIMETHYL SULFOXIDE, ... | | Authors: | Krojer, T, Kozielski, F, Sele, C, Nyblom, M, Fisher, S.Z, Knecht, W. | | Deposit date: | 2024-06-30 | | Release date: | 2025-08-20 | | Method: | X-RAY DIFFRACTION (1.509 Å) | | Cite: | Ensemble model of ligand-free SARS-CoV-2 NSP10-NSP14 (ExoN) and in complex with partially bound VT00123
To Be Published
|
|
9IMK
 | |
9IMM
 | |
9KGJ
 | |
9KGN
 | |
9KGQ
 | |
9KGR
 | |
9KGS
 | |
9KVD
 | | Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with triple-nAb 3G5, 4H5 and 4C11 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, The heavy chain of 3G5, ... | | Authors: | Sun, H, Jiang, Y, Wang, S, Zheng, Z, Li, S, Zheng, Q. | | Deposit date: | 2024-12-05 | | Release date: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (3.44 Å) | | Cite: | Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with triple-nAb 3G5, 4H5 and 4C11
To Be Published
|
|
9KVE
 | | Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with triple-nAb 4H1, 4A5 and 4C1 | | Descriptor: | Spike protein S1, The heavy chain of 4A5, The heavy chain of 4C1, ... | | Authors: | Sun, H, Jiang, Y, Wang, S, Zheng, Z, Li, S, Zheng, Q. | | Deposit date: | 2024-12-05 | | Release date: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with triple-nAb 4H1, 4A5 and 4C1
To Be Published
|
|
9KVF
 | | Cryo-EM structure of SARS-CoV-2 EG.1 spike protein in complex with triple-nAb 4A5, 4C1 and 2E10 | | Descriptor: | 2E10 heavy chain, 2E10 light chain, 4A5 heavy chain, ... | | Authors: | Sun, H, Jiang, Y, Wang, S, Zheng, Z, Li, S, Zheng, Q. | | Deposit date: | 2024-12-05 | | Release date: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structure of SARS-CoV-2 EG.1 spike protein in complex with triple-nAb 4A5, 4C1 and 2E10
To Be Published
|
|
9MI3
 | | Cryo-EM structure of SARS-CoV-2 spike protein in complex with neutralizing human antibody WRAIR-2008 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, WRAIR-2008 antibody Fab heavy chain, ... | | Authors: | Jensen, J.L, Thomas, P.V, Joyce, M.G. | | Deposit date: | 2024-12-12 | | Release date: | 2025-08-20 | | Last modified: | 2025-10-22 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | First-generation N-terminal domain supersite public antibodies retain activity against Omicron-derived lineages and protect mice against Omicron BA.5 challenge.
Mbio, 16, 2025
|
|
9N3M
 | | SARS-CoV-2 Mpro L50F/E166A/L167F triple mutant bound to inhibitor | | Descriptor: | (1S,2S,4S)-2-{[3-cyclopropyl-N-(4-methoxy-1H-indole-2-carbonyl)-L-alanyl]amino}-1-hydroxy-4-methyl-5-(methylamino)-5-oxopentane-1-sulfonic acid, 3C-like proteinase | | Authors: | Lu, J, Chen, P, Demmon, S, Fischer, C, Vederas, J.C, Lemieux, M.J. | | Deposit date: | 2025-01-31 | | Release date: | 2025-08-20 | | Last modified: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural insights into the nirmatrelvir-resistant SARS-CoV-2 M pro L50F/E166A/L167F triple mutant-inhibitor-complex reveal strategies for next generation coronaviral inhibitor design.
Rsc Med Chem, 2025
|
|
9UCN
 | | Monomer of SARS-CoV-2 nsp4CTD | | Descriptor: | Non-structural protein 4 | | Authors: | Meng, L, Pei, K, Tang, C. | | Deposit date: | 2025-04-04 | | Release date: | 2025-08-20 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Structural Dynamics of SARS-CoV-2 NSP4 C-terminal Domain and Implications for Viral Processing.
J.Mol.Biol., 437, 2025
|
|
9ATQ
 | | XBB.1.5 spike/Nanosota-8 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | | Deposit date: | 2024-02-27 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of XBB.1.5 spike and Nanosota-8 complex
To Be Published
|
|
9ATR
 | | local refinement of XBB.1.5 spike/Nanosota-8 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-8, ... | | Authors: | Ye, G, Bu, F, Liu, B, Li, F. | | Deposit date: | 2024-02-27 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structure of XBB.1.5 spike and Nanosota-3C complex
To Be Published
|
|
9BND
 | | SARS-CoV-2 spike HexaPro protein in complex with T0A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
|
|
9BNE
 | | SARS-CoV-2 spike HexaPro protein in complex with T3A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
|
|
9BNF
 | | SARS-CoV-2 spike HexaPro protein in complex with T5A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
|
|
9BNG
 | | SARS-CoV-2 spike HexaPro protein in complex with T18A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
|
|
9GHN
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of Q256A | | Descriptor: | 1,2-ETHANEDIOL, 3C-like proteinase nsp5, CHLORIDE ION, ... | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-15 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of Q256A
To Be Published
|
|
9GHO
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of S284A | | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-15 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of S284A
To Be Published
|
|
9GI6
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of N214A | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Replicase polyprotein 1a, ... | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-17 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of N214A
To Be Published
|
|
