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코로나 바이러스
코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스(Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2)를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.

Created: 2020-03-11 (last edited: 3 weeks ago)2020-09-03
전체 엔트리 (390)대표구조 (167)최신 엔트리 (19)
7CHB
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CRYSTAL STRUCTURE OF THE SARS-COV-2 RBD IN COMPLEX WITH BD-236 FAB
Descriptor:BD-236 Fab heavy chain, BD-236 Fab light chain, SARS-coV-2 Receptor Binding Domain, ...
Authors:Junyu, X., Qinyu, Z.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the SARS-CoV-2 S RBD in complex with BD-236 Fab
To Be Published
7CHE
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CRYSTAL STRUCTURE OF THE SARS-COV-2 RBD IN COMPLEX WITH BD-236 FAB AND BD-368-2 FAB
Descriptor:BD-236 Fab heavy chain, BD-236 Fab light chain, SARS-coV-2 Receptor Binding Domain, ...
Authors:Xiao, J., Zhu, Q.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (3.416 Å)
Cite:Crystal structure of the SARS-CoV-2 RBD in complex with BD-236 Fab and BD-368-2 Fab
To Be Published
7A5R
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COMPLEX OF SARS-COV-2 SPIKE AND CR3022 FAB (NON-UNIFORM REFINEMENT)
Descriptor:CR3022 Fab Heavy Chain, CR3022 Fab Light Chain, Spike glycoprotein, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-08-21
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
To be published
7CH4
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CRYSTAL STRUCTURE OF THE SARS-COV-2 S RBD IN COMPLEX WITH BD-604 FAB
Descriptor:BD-604 Fab H, BD-604 Fab L, Spike glycoprotein
Authors:Du, S., Xiao, J.Y.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal structure of the SARS-CoV-2 S RBD in complex with BD-604 Fab
To Be Published
7A5S
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COMPLEX OF SARS-COV-2 SPIKE AND CR3022 FAB (HOMOGENEOUS REFINEMENT)
Descriptor:CR3022 Fab Heavy Chain, CR3022 Fab Light Chain, Spike glycoprotein, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-08-21
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
To be published
7CX9
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CRYSTAL STRUCTURE OF THE SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH INZ-1
Descriptor:3C protein, 3-iodanyl-1~{H}-indazole-7-carbaldehyde, GLYCEROL, ...
Authors:Zeng, R., Liu, X.L., Qiao, J.X., Nan, J.S., Wang, Y.F., Li, Y.S., Yang, S.Y., Lei, J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structure of the SARS-CoV-2 main protease in complex with INZ-1
To Be Published
7A97
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 2 ACE2 BOUND
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7A95
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND AND 1 RBD ERECT IN CLOCKWISE DIRECTION
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7CHH
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CRYO-EM STRUCTURE OF THE SARS-COV-2 S-6P IN COMPLEX WITH BD-368-2 FABS
Descriptor:Spike glycoprotein, BD-368-2 Fab heavy chain, BD-368-2 Fab light chain, ...
Authors:Xiao, J., Zhu, Q., Wang, G.
Deposit date:2020-07-05
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs
To Be Published
7CHC
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CRYSTAL STRUCTURE OF THE SARS-COV-2 S RBD IN COMPLEX WITH BD-629 FAB AND BD-368-2 FAB
Descriptor:BD-629 Fab H, IGK@ protein, Spike glycoprotein, ...
Authors:Du, S., Xiao, J.Y.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab and BD-368-2 Fab
To Be Published
7CH5
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CRYSTAL STRUCTURE OF THE SARS-COV-2 S RBD IN COMPLEX WITH BD-629 FAB
Descriptor:BD-629 Fab H, BD-629 Fab L, Spike glycoprotein
Authors:Du, S., Xiao, J.Y.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the SARS-CoV-2 S RBD in complex with BD-629 Fab
To Be Published
7A91
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DISSOCIATED S1 DOMAIN OF SARS-COV-2 SPIKE BOUND TO ACE2 (NON-UNIFORM REFINEMENT)
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7JZ0
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CRYSTAL STRUCTURE OF SARS-COV-2 NSP16/10 HETERODIMER IN COMPLEX WITH (M7GPPPA2M)PUPUPAPAPA (CAP-1) AND S-ADENOSYL-L-HOMOCYSTEINE (SAH).
Descriptor:2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*(A2M)P*UP*U)-3'), ...
Authors:Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-01
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).
To Be Published
7A94
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7JYY
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CRYSTAL STRUCTURE OF SARS-COV-2 NSP16/10 HETERODIMER IN COMPLEX WITH (M7GPPPA)PUPUPAPAPA (CAP-0) AND S-ADENOSYLMETHIONINE (SAM).
Descriptor:2'-O-methyltransferase, Non-structural protein 10, RNA (5'-D(*(M7G))-R(P*AP*UP*UP*A)-3'), ...
Authors:Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-09-01
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).
To Be Published
7A96
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND AND 1 RBD ERECT IN ANTICLOCKWISE DIRECTION
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7JVZ
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SARS COV-2 MAIN PROTEASE 3CLPRO, ROOM TEMPERATURE, DAMAGE FREE XFEL MONOCLINIC STRUCTURE
Descriptor:3C-like proteinase
Authors:Schmidt, M., Malla, T.
Deposit date:2020-08-24
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:SARS CoV-2 MAIN PROTEASE 3CLpro, ROOM TEMPERATURE, DAMAGE FREE XFEL MONOCLINIC STRUCTURE
To Be Published
7A93
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 2 RBDS ERECT
Descriptor:Spike glycoprotein
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Receptor Binding and Priming of SARS-CoV-2 Spike for Membrane Fusion
To be published
7CHF
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CRYSTAL STRUCTURE OF THE SARS-COV-2 RBD IN COMPLEX WITH BD-604 FAB AND BD-368-2 FAB
Descriptor:BD-604 Fab heavy chain, BD-604 Fab light chain, SARS-coV-2 Receptor Binding Domain, ...
Authors:Xiao, J., Zhu, Q.
Deposit date:2020-07-05
Release date:2020-09-16
Method:X-RAY DIFFRACTION (2.674 Å)
Cite:Crystal structure of the SARS-CoV-2 RBD in complex with BD-604 Fab and BD-368-2 Fab
To Be Published
7JU7
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THE CRYSTAL STRUCTURE OF SARS-COV-2 MAIN PROTEASE IN COMPLEX WITH MASITINIB
Descriptor:3C-like proteinase, Masitinib, DIMETHYL SULFOXIDE, ...
Authors:Tan, K., Maltseva, N.I., Welk, L.F., Jedrzejczak, R.P., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-08-19
Release date:2020-09-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The crystal structure of SARS-CoV-2 Main Protease in complex with masitinib.
To Be Published
7JYC
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CRYSTAL STRUCTURE OF SARS-COV-2 MAIN PROTEASE (3CLPRO/MPRO) IN COMPLEX WITH COVALENT INHIBITOR NARLAPREVIR
Descriptor:3C-like proteinase, (1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropyla mino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, DIMETHYL SULFOXIDE, ...
Authors:Andi, B., Kumaran, D., Kreitler, D.F., Soares, A.S., Shi, W., Jakoncic, J., Fuchs, M.R., Keereetaweep, J., Shanklin, J., McSweeney, S.
Deposit date:2020-08-30
Release date:2020-09-09
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Hepatitis C Virus NSP3/NSP4A Inhibitors as Promising Lead Compounds for the Design of New Covalent Inhibitors for SARS-CoV-2 3CLpro/Mpro Protease
To Be Published
7CJD
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CRYSTAL STRUCTURE OF THE SARS-COV-2 PLRO C111S MUTANT
Descriptor:Replicase polyprotein 1ab, ZINC ION, 1,2-ETHANEDIOL
Authors:Gao, X., Cui, S.
Deposit date:2020-07-10
Release date:2020-09-02
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Crystal structure of SARS-CoV-2 papain-like protease.
Acta Pharm Sin B, 2020
7CJM
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SARS COV-2 PLPRO IN COMPLEX WITH GRL0617
Descriptor:Non-structural protein 3, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION
Authors:Fu, Z., Huang, H.
Deposit date:2020-07-11
Release date:2020-09-02
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:SARS CoV-2 PLpro in complex with 6-thioguanine
To Be Published
7C6U
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CRYSTAL STRUCTURE OF SARS-COV-2 COMPLEXED WITH GC376
Descriptor:3C-like proteinase, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid
Authors:Fu, L., Feng, Y., Qi, J., Gao, F.G.
Deposit date:2020-05-22
Release date:2020-09-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of SARS-CoV-2 complexed with GC376
To Be Published
7C6S
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CRYSTAL STRUCTURE OF THE SARS-COV-2 MAIN PROTEASE COMPLEXED WITH BOCEPREVIR
Descriptor:3C-like proteinase, boceprevir (bound form)
Authors:Fu, L., Feng, Y.
Deposit date:2020-05-22
Release date:2020-09-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the SARS-CoV-2 main protease complexed with Boceprevir
To Be Published
168889
건을2020-09-16부터공개중