8XEF
 
 | | Cocktail GC2050-GC2225 | | Descriptor: | GC2050 heavy chain, GC2050 light chain, GC2225 heavy chain, ... | | Authors: | Feng, L.L. | | Deposit date: | 2023-12-11 | | Release date: | 2024-12-11 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (4.41 Å) | | Cite: | XBB.1.5 RBD in complex with GC2050 and GC2225
To Be Published
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9CJ6
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8JAP
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8V5V
 | | Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2,Fibritin, ... | | Authors: | Olmedillas, E, Diaz, R, Hastie, K, Ollmann-Saphire, E. | | Deposit date: | 2023-12-01 | | Release date: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structure of a SARS-CoV-2 spike S2 subunit in a pre-fusion, open conformation
To Be Published
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8XRQ
 | | SARS-CoV-2 BA.1 spike RBD in complex bound with VacBB-639 | | Descriptor: | Heavy chain of VacBB 639 Fab, Light chain of VacBB 639 Fab, Spike protein S1 | | Authors: | Liu, C.C, Ju, B, Zhang, Z. | | Deposit date: | 2024-01-08 | | Release date: | 2024-12-18 | | Last modified: | 2025-03-26 | | Method: | ELECTRON MICROSCOPY (4.19 Å) | | Cite: | Rapid clonal expansion and somatic hypermutation contribute to the fate of SARS-CoV-2 broadly neutralizing antibodies.
J Immunol., 214, 2025
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9BIH
 | | SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA with 1 nucleotide bulge | | Descriptor: | RNA (34-mer), RNA (35-mer), Uridylate-specific endoribonuclease nsp15 | | Authors: | Wright, Z.M, Butay, K.J, Krahn, J.M, Borgnia, M.J, Stanley, R.E. | | Deposit date: | 2024-04-23 | | Release date: | 2024-12-18 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Spontaneous base flipping helps drive Nsp15's preferences in double stranded RNA substrates.
Nat Commun, 16, 2025
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8ZPP
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9BF9
 | | Human LAG-3-HLA-DR1 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, HLA class II histocompatibility antigen DR beta chain, ... | | Authors: | Petersen, J, Rossjohn, J. | | Deposit date: | 2024-04-17 | | Release date: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal structure of the human LAG-3-HLA-DR1-peptide complex.
Sci Immunol, 9, 2024
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8RJ5
 | | P1-15 T-cell Receptor bound to HLA A*2402-NF9 pMHC complex | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, P1-15 T-cell Receptor Alpha Chain, ... | | Authors: | Wall, A, Sewell, A.K, Motozono, C, Rizkallah, P.J, Fuller, A. | | Deposit date: | 2023-12-20 | | Release date: | 2025-01-01 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | NF9 T-cell Receptor bound to HLA A*2402-NF9 pMHC complex (Paper Pending)
To Be Published
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8RJH
 | | HLA A*2402-NF9_6F pMHC complex | | Descriptor: | ASN-TYR-ASN-TYR-LEU-PHE-ARG-LEU-PHE, Beta-2-microglobulin, MHC class I antigen | | Authors: | Wall, A, Sewell, A.K, Motozono, C, Rizkallah, P.J, Fuller, A. | | Deposit date: | 2023-12-21 | | Release date: | 2025-01-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | HLA A*2402-NF9_6F pMHC complex
To Be Published
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8RJI
 | | HLA A*2402-NF9_5R pMHC complex | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Spike glycoprotein | | Authors: | Wall, A, Motozono, C, Sewell, A.K, Rizkallah, P.J, Fuller, A. | | Deposit date: | 2023-12-21 | | Release date: | 2025-01-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | HLA A*2402-NF9_5R pMHC complex
To Be Published
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8Y4D
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8Y4G
 | | Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with Bofutrelvir | | Descriptor: | 3C-like proteinase nsp5, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | | Authors: | Zeng, P, Wang, W.W, Zhang, J, Li, J. | | Deposit date: | 2024-01-30 | | Release date: | 2025-01-08 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Inhibitory efficacy and structural insights of Bofutrelvir against SARS-CoV-2 M pro mutants and MERS-CoV M pro.
Commun Biol, 8, 2025
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8Y4H
 | | Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with Bofutrelvir | | Descriptor: | 3C-like proteinase nsp5, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | | Authors: | Guo, L, Wang, W.W, Zhang, J, Li, J. | | Deposit date: | 2024-01-30 | | Release date: | 2025-01-08 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Inhibitory efficacy and structural insights of Bofutrelvir against SARS-CoV-2 M pro mutants and MERS-CoV M pro.
Commun Biol, 8, 2025
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8YDP
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8YDQ
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8YDR
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8YDS
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8YDT
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8YDU
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8YDV
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8YDW
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8YDX
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8YDZ
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9IUP
 | | KP.3 RBD in complex with ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | | Authors: | Feng, L.L. | | Deposit date: | 2024-07-22 | | Release date: | 2025-01-15 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural and molecular basis of the epistasis effect in enhanced affinity between SARS-CoV-2 KP.3 and ACE2.
Cell Discov, 10, 2024
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