신종 코로나바이러스 특집 콘텐츠

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코로나 바이러스, 2020. David S. Goodsell @ RCSB PDB에 의한 오리지널 일러스트를 수정

신종 코로나바이러스 감염증 (Novel Coronavirus disease 2019:COVID-19)의 확산이 세계적으로 매우 큰 문제가 되고 있습니다. 시급히 새로운 바이러스（Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2）를 이해하고 효과적인 약을 개발하기 위해, 신속하게 구조 생물학 연구가 시작되고 있습니다. PDBj는 사용자의 편의를 도모하기 위해 신종 코로나바이러스의 특집 페이지를 제공하고 있습니다. 매주 수요일에 최신 항목이 추가됩니다.

바이러스 단백질에 관한 해설기사는 아래의 「이달의 분자」 페이지를 참조하십시오.

「전체 엔트리」 탭에는, 모든 PDB ID가 포함되어 있습니다. 이용자가 전체의 독립된 엔트리를 검색하고 싶을 때 사용하실 수 있으며, 동일 저자에 의한 그룹등록의 엔트리도 전부 구별되어 있습니다. 「대표구조」 탭에는, 분해능이 가장 높은 대표구조만을 표지하고 있습니다. 아미노산 서열이 100 % 일치하는 PDB 엔트리의 경우, 다른 리간드를 포함하여도 대표구조에는 제외됩니다. 「최신 엔트리」 탭은, 이번주 공개된 가장 최근의 엔트리 입니다.

Created: 2020-09-03 (last edited: more than 1 year ago)

전체 엔트리 (4459)대표구조 (1984)최신 엔트리 (16)

7VHJ

Furin Site deletion of SARS-CoV-2 spike
Descriptor:	Spike glycoprotein
Authors:	Wang, X, Cui, Z.
Deposit date:	2021-09-22
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Furin Site deletion of SARS-CoV-2 Spike To Be Published

7VHK

S1-S2 deletion S-2P trimer(3 down)
Descriptor:	Spike glycoprotein
Authors:	Wang, X, Cui, Z.
Deposit date:	2021-09-22
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Furin Site deletion S-2P trimer To Be Published

7VHL

Double deletion S-2P trimer(1 Up)
Descriptor:	Spike glycoprotein
Authors:	Wang, X, Cui, Z.
Deposit date:	2021-09-22
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (3.9 Å)
Cite:	Double deletion S-2P trimer(1 Up) To Be Published

7VHM

Double deletion S-2P trimer(3 down)
Descriptor:	Spike glycoprotein
Authors:	Wang, L, Wang, X, Wang, X.
Deposit date:	2021-09-22
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Double deletion S-2P trimer(3 down) To Be Published

7WSE

Cryo-EM structure of SARS-CoV-2 spike receptor-binding domain complexed with its receptor minke whale ACE2
Descriptor:	Angiotensin-converting enzyme, Spike protein S1, ZINC ION
Authors:	Li, S, Han, P.
Deposit date:	2022-01-29
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (2.93 Å)
Cite:	Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals. Natl Sci Rev, 9, 2022

7YE7

Crystal structure of SARS-CoV-2 soluble dimeric ORF9b
Descriptor:	N-OCTANE, ORF9b protein, nonane
Authors:	Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F.
Deposit date:	2022-07-05
Release date:	2022-10-19
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.95 Å)
Cite:	Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism. Sci China Life Sci, 66, 2023

7YE8

Crystal structure of SARS-CoV-2 refolded dimeric ORF9b
Descriptor:	N-OCTANE, ORF9b protein
Authors:	Jin, X, Chai, Y, Qi, J, Song, H, Gao, G.F.
Deposit date:	2022-07-05
Release date:	2022-10-19
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3.01 Å)
Cite:	Structural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism. Sci China Life Sci, 66, 2023

7YQT

SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.45 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQU

SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.19 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQV

pH 5.5 SARS-CoV-2 BA.2.75 S Trimer (1 RBD Up)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.58 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQW

SARS-CoV-2 BA.2.75 S Trimer (3 RBD Down)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.51 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQX

SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.72 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQY

SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.74 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YQZ

SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (state3)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S309 heavy chain, S309 light chain, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.84 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YR0

SARS-CoV-2 BA.2.75 S Trimer in complex with S309 (interface)
Descriptor:	Heavy chain of S309, IGK@ protein, Spike protein S1, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.98 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YR1

SARS-CoV-2 BA.2.75 S Trimer in complex with XG2v024
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.62 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YR2

SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

7YR3

SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	Wang, L.
Deposit date:	2022-08-08
Release date:	2022-10-19
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.52 Å)
Cite:	Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75. Cell Host Microbe, 30, 2022

8D8Q

SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ...
Authors:	Du, J, Cui, J, Pallesen, J.
Deposit date:	2022-06-08
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022

8D8R

SARS-CoV-2 Spike RBD in complex with DMAb 2196
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ...
Authors:	Du, J, Cui, J, Pallesen, J.
Deposit date:	2022-06-08
Release date:	2022-10-19
Method:	ELECTRON MICROSCOPY (4.1 Å)
Cite:	DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022

7WB5

local structure of hu33 and spike
Descriptor:	Surface glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hu33 heavy chain, ...
Authors:	Pulan, L.
Deposit date:	2021-12-15
Release date:	2022-10-26
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	A non-ACE2-blocking neutralizing antibody against Omicron-included SARS-CoV-2 variants. Signal Transduct Target Ther, 7, 2022

7ZIT

14-3-3 in complex with SARS-COV2 N phospho-peptide
Descriptor:	14-3-3 protein zeta/delta, ACETATE ION, BENZOIC ACID, ...
Authors:	Eisenreichova, A, Boura, E.
Deposit date:	2022-04-08
Release date:	2022-10-26
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.79 Å)
Cite:	Structural basis for SARS-CoV-2 nucleocapsid (N) protein recognition by 14-3-3 proteins. J.Struct.Biol., 214, 2022

8ERQ

SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-10-12
Release date:	2022-10-26
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378, 2022

8ERR

SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2022-10-12
Release date:	2022-10-26
Last modified:	2022-11-23
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Science, 378, 2022

8GS6

Structure of the SARS-CoV-2 BA.2.75 spike glycoprotein (closed state 1)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:	Anraku, Y, Tabata-Sasaki, K, Kita, S, Fukuhara, H, Maenaka, K, Hashiguchi, T.
Deposit date:	2022-09-05
Release date:	2022-10-26
Last modified:	2023-03-29
Method:	ELECTRON MICROSCOPY (2.86 Å)
Cite:	Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant. Cell Host Microbe, 30, 2022

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Displayed results:	25
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