8IFY
 
 | Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2023-02-20 | 公開日 | 2023-08-30 | 最終更新日 | 2025-07-02 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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8IFZ
 
 | Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 spike protein receptor-binding domain in complex with white-tailed deer ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | 著者 | Han, P, Meng, Y.M, Qi, J.X. | 登録日 | 2023-02-20 | 公開日 | 2023-08-30 | 最終更新日 | 2025-06-25 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of white-tailed deer, Odocoileus virginianus , ACE2 recognizing all the SARS-CoV-2 variants of concern with high affinity. J.Virol., 97, 2023
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8STY
 
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8STZ
 
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8SXR
 
 | Crystal structure of SARS-CoV-2 Mpro with C5a | 分子名称: | 3C-like proteinase nsp5, N-[(4-chlorothiophen-2-yl)methyl]-N-[4-(dimethylamino)phenyl]-2-(5-hydroxyisoquinolin-4-yl)acetamide | 著者 | Worrall, L.J, Kenward, C, Lee, J, Strynadka, N.C.J. | 登録日 | 2023-05-23 | 公開日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.114 Å) | 主引用文献 | A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect, 12, 2023
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7U92
 
 | SARS-CoV-2 Main Protease (Mpro) in Complex with ML1006a | 分子名称: | (1R,2S,5S)-N-{(2S,3R)-4-(azetidin-1-yl)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, CHLORIDE ION | 著者 | Westberg, M, Fernandez, D, Lin, M.Z. | 登録日 | 2022-03-09 | 公開日 | 2023-09-06 | 最終更新日 | 2024-11-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations. Sci Transl Med, 16, 2024
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7Y0O
 
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7YBK
 
 | SARS-CoV-2 B.1.620 variant spike (open state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, X, Fu, W. | 登録日 | 2022-06-29 | 公開日 | 2023-09-06 | 最終更新日 | 2025-06-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of SARS-CoV-2 spike protein alert noteworthy sites for the potential approaching variants. Virol Sin, 37, 2022
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7YLB
 
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8GSB
 
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7XY3
 
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7XY4
 
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7Y0N
 
 | SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R15-F7, ... | 著者 | Wang, L. | 登録日 | 2022-06-05 | 公開日 | 2023-09-13 | 最終更新日 | 2025-06-25 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody To Be Published
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8AZC
 
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8AZD
 
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8F0I
 
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8GTV
 
 | SARS-CoV-2 3CL protease (3CLpro) in complex with compound JZD-07 | 分子名称: | 3C-like proteinase, 4-[(2~{S})-4-(3,4-dichlorophenyl)-2-(morpholin-4-ylmethyl)piperazin-1-yl]carbonyl-1~{H}-quinolin-2-one | 著者 | Su, H.X, Nie, T.Q, Xie, H, Li, M.J, Xu, Y.C. | 登録日 | 2022-09-08 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Development of novel inhibitors against SARS-CoV-2 3CLpro To Be Published
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8GTW
 
 | SARS-CoV-2 3CL protease (3CLpro) in complex with compound JZD-26 | 分子名称: | (2S)-4-(3,4-dichlorophenyl)-1-[(2-oxidanylidene-1H-quinolin-4-yl)carbonyl]-N-[3,3,3-tris(fluoranyl)propyl]piperazine-2-carboxamide, 3C-like proteinase | 著者 | Su, H.X, Nie, T.Q, Xie, H, Li, M.J, Xu, Y.C. | 登録日 | 2022-09-08 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Development of novel inhibitors against SARS-CoV-2 3CLpro To Be Published
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8U2X
 
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7YR4
 
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8CQ1
 
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8EDF
 
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8GVD
 
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8GVY
 
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8GWJ
 
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