8GTV

SARS-CoV-2 3CL protease (3CLpro) in complex with compound JZD-07

Summary for 8GTV

• Entry DOI: 10.2210/pdb8gtv/pdb
• Descriptor: 3C-like proteinase, 4-[(2~{S})-4-(3,4-dichlorophenyl)-2-(morpholin-4-ylmethyl)piperazin-1-yl]carbonyl-1~{H}-quinolin-2-one (3 entities in total)
• Functional Keywords: mpro, viral protein-inhibitor complex, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 68653.90

Authors

Su, H.X.,Nie, T.Q.,Xie, H.,Li, M.J.,Xu, Y.C. (deposition date: 2022-09-08, release date: 2023-09-13)

• Primary citation: Xu, Y.C.,Zang, Y.,Zhou, Y.; Development of novel inhibitors against SARS-CoV-2 3CLpro; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)