9BND
 
 | | SARS-CoV-2 spike HexaPro protein in complex with T0A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
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9BNE
 | | SARS-CoV-2 spike HexaPro protein in complex with T3A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
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9BNF
 | | SARS-CoV-2 spike HexaPro protein in complex with T5A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
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9BNG
 | | SARS-CoV-2 spike HexaPro protein in complex with T18A trimeric antagonist | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(XVIII) chain,Processed angiotensin-converting enzyme 2, ... | | Authors: | Young, T. | | Deposit date: | 2024-05-02 | | Release date: | 2025-08-27 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal COVID antagonist
To Be Published
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9GHN
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of Q256A | | Descriptor: | 1,2-ETHANEDIOL, 3C-like proteinase nsp5, CHLORIDE ION, ... | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-15 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of Q256A
To Be Published
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9GHO
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of S284A | | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-15 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of S284A
To Be Published
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9GI6
 | | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of N214A | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Replicase polyprotein 1a, ... | | Authors: | Creon, A, Scheer, T.E.S, Lane, T.J, Rahmani Mashhour, A, Guenther, S, Reinke, P.Y.A, Meents, A, Chapman, H.N. | | Deposit date: | 2024-08-17 | | Release date: | 2025-09-03 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure of SARS-CoV-2 Main Protease (Mpro) with mutation of N214A
To Be Published
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9JEB
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8ZRD
 | | The complex structure of SARS-CoV-2 RBD and llama single-domain antibody S4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, llama single-domain antibody S4 | | Authors: | Chen, L. | | Deposit date: | 2024-06-04 | | Release date: | 2025-09-10 | | Method: | X-RAY DIFFRACTION (2.715 Å) | | Cite: | Identification of a potent SARS-CoV-2 neutralizing nanobody targeting the receptor-binding domain of the spike protein.
Int.J.Biol.Macromol., 281, 2024
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9PYS
 | | NMR RDC refinement of the helical domain of the SARS-CoV-2 monomeric Main Protease (MPROH41Q,10-306) | | Descriptor: | 3C-like proteinase nsp5 | | Authors: | Smith, M.J, Ying, J, Shen, Y, Louis, J.M, Bax, A. | | Deposit date: | 2025-08-08 | | Release date: | 2025-09-17 | | Method: | SOLUTION NMR | | Cite: | Solution Domain Dynamics of Monomeric SARS-CoV-2 Main Protease Revealed by Optimized NMR Residual Dipolar Coupling Measurements.
To Be Published
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9PYZ
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9PZ0
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9Q1J
 | | Cryo-EM structure of SARS-CoV-2 nsp10-nsp14 E191A mutant-T20P14-R complex | | Descriptor: | MAGNESIUM ION, Non-structural protein 10, Proofreading exoribonuclease, ... | | Authors: | Yang, Y, Liu, C, Liu, B. | | Deposit date: | 2025-08-14 | | Release date: | 2025-09-24 | | Last modified: | 2025-10-15 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Molecular basis of SARS-CoV-2 proofreading enzyme-mediated resistance to remdesivir.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9VS1
 | | Crystal structure of SARS-CoV-2 3CL protease in complex with compound 15 | | Descriptor: | 1,2-ETHANEDIOL, 3C-like proteinase, 4-chloranyl-3-[6-methyl-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-2,4,5-tris(oxidanylidene)-1-[[3,4,5-tris(fluoranyl)phenyl]methyl]pyrido[4,3-d]pyrimidin-7-yl]benzenecarbonitrile | | Authors: | Yamamoto, S, Taoda, Y. | | Deposit date: | 2025-07-08 | | Release date: | 2025-09-24 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Design, synthesis and biological evaluation of novel quinazolinedione derivatives as non-covalent SARS-CoV-2 3CL protease inhibitors.
Bioorg.Med.Chem.Lett., 129, 2025
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8YUB
 | | Crystal structure of SARS-CoV-2 ConSp RBD in complex with neutralizing antibody CC25.4 Fab | | Descriptor: | 1,2-ETHANEDIOL, Neutralizing antibody CC25.4 heavy chain, Neutralizing antibody CC25.4 light chain, ... | | Authors: | Kang, J.M, Yuan, M, Han, B.W, Wilson, I.A. | | Deposit date: | 2024-03-27 | | Release date: | 2025-10-01 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structure and antigenic characteristics of consensus sequence-based SARS-CoV-2 antigen
To Be Published
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8YUC
 | | Crystal structure of SARS-CoV-2 ConSp RBD in complex with antibodies PDI222 Fab and COVA1-16 Fab | | Descriptor: | COVA1-16 heavy chain, COVA1-16 light chain, PDI222 heavy chain, ... | | Authors: | Kang, J.M, Yuan, M, Han, B.W, Wilson, I.A. | | Deposit date: | 2024-03-27 | | Release date: | 2025-10-01 | | Method: | X-RAY DIFFRACTION (4.51 Å) | | Cite: | Structure and antigenic characteristics of consensus sequence-based SARS-CoV-2 antigen
To Be Published
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9BF7
 | | SARS-CoV-2 Papain-like Protease (PLpro) C111S Untagged Crystal Structure | | Descriptor: | ACETATE ION, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Al-Homoudi, A.I, Brunzelle, J.S, Gavande, N, Kovari, L.C. | | Deposit date: | 2024-04-17 | | Release date: | 2025-10-01 | | Last modified: | 2025-10-15 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Human Structural Homologues of SARS-CoV-2 PL pro as Anti-Targets: A Strategic Panel Analysis.
MicroPubl Biol, 2025, 2025
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9SAO
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9SAP
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9SAQ
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9SAR
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8XZ0
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8XZ4
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8XZ5
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9C7S
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