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- PDB-6vmk: Crystal structure of human Complement Factor D with anti-Factor D... -

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基本情報

登録情報
データベース: PDB / ID: 6vmk
タイトルCrystal structure of human Complement Factor D with anti-Factor D Fab 20D12
要素
  • Complement factor D
  • Fab Y49R heavy chain
  • Fab Y49R light chain
キーワードHYDROLASE/IMMUNE SYSTEM / CFD / Factor D / Fab / HYDROLASE / HYDROLASE-IMMUNE SYSTEM complex
機能・相同性
機能・相同性情報


complement factor D / Alternative complement activation / complement activation / complement activation, alternative pathway / serine-type peptidase activity / platelet alpha granule lumen / protein maturation / response to bacterium / Platelet degranulation / secretory granule lumen ...complement factor D / Alternative complement activation / complement activation / complement activation, alternative pathway / serine-type peptidase activity / platelet alpha granule lumen / protein maturation / response to bacterium / Platelet degranulation / secretory granule lumen / ficolin-1-rich granule lumen / serine-type endopeptidase activity / Neutrophil degranulation / proteolysis / extracellular space / extracellular exosome / extracellular region
類似検索 - 分子機能
Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Serine proteases, trypsin family, histidine active site. / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, serine active site. / Serine proteases, trypsin domain profile. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Peptidase S1, PA clan, chymotrypsin-like fold ...Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Serine proteases, trypsin family, histidine active site. / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, serine active site. / Serine proteases, trypsin domain profile. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Peptidase S1, PA clan, chymotrypsin-like fold / Immunoglobulins / Peptidase S1, PA clan / Immunoglobulin-like / Sandwich / Mainly Beta
類似検索 - ドメイン・相同性
Complement factor D
類似検索 - 構成要素
生物種Homo sapiens (ヒト)
手法X線回折 / シンクロトロン / 分子置換 / 解像度: 3.01 Å
データ登録者Wu, P. / Harris, S.F. / Eigenbrot, C.
引用ジャーナル: To Be Published
タイトル: Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12
著者: Dion, M. / Wu, P. / Morando, A. / Bullen, G. / Shatz, W. / Harris, S.F. / Eigenbrot, C. / Loyet, K.M. / Yadav, D. / Tassew, N. / Booler, H. / Scheer, J. / Kelley, R.F. / Tesar, D.B.
履歴
登録2020年1月28日登録サイト: RCSB / 処理サイト: RCSB
改定 1.02021年2月3日Provider: repository / タイプ: Initial release
改定 1.12024年4月3日Group: Data collection / Database references / Refinement description
カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession
改定 1.22024年10月30日Group: Structure summary
カテゴリ: pdbx_entry_details / pdbx_modification_feature
Item: _pdbx_entry_details.has_protein_modification

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構造の表示

構造ビューア分子:
MolmilJmol/JSmol

ダウンロードとリンク

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集合体

登録構造単位
W: Complement factor D
L: Fab Y49R light chain
M: Fab Y49R heavy chain
C: Complement factor D
A: Fab Y49R light chain
B: Fab Y49R heavy chain
F: Complement factor D
D: Fab Y49R light chain
E: Fab Y49R heavy chain
I: Complement factor D
G: Fab Y49R light chain
H: Fab Y49R heavy chain
N: Complement factor D
J: Fab Y49R light chain
K: Fab Y49R heavy chain
Q: Complement factor D
O: Fab Y49R light chain
P: Fab Y49R heavy chain
T: Complement factor D
R: Fab Y49R light chain
S: Fab Y49R heavy chain
X: Complement factor D
U: Fab Y49R light chain
V: Fab Y49R heavy chain
a: Complement factor D
Y: Fab Y49R light chain
Z: Fab Y49R heavy chain
d: Complement factor D
b: Fab Y49R light chain
c: Fab Y49R heavy chain
g: Complement factor D
e: Fab Y49R light chain
f: Fab Y49R heavy chain
j: Complement factor D
h: Fab Y49R light chain
i: Fab Y49R heavy chain
m: Complement factor D
k: Fab Y49R light chain
l: Fab Y49R heavy chain
p: Complement factor D
n: Fab Y49R light chain
o: Fab Y49R heavy chain
s: Complement factor D
q: Fab Y49R light chain
r: Fab Y49R heavy chain
v: Complement factor D
t: Fab Y49R light chain
u: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)1,146,01876
ポリマ－1,143,39248
非ポリマー2,62628
水27,0771503
1
W: Complement factor D
L: Fab Y49R light chain
M: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
2
C: Complement factor D
A: Fab Y49R light chain
B: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
3
F: Complement factor D
D: Fab Y49R light chain
E: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,5544
ポリマ－71,4623
非ポリマー921
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
4
I: Complement factor D
G: Fab Y49R light chain
H: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,5544
ポリマ－71,4623
非ポリマー921
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
5
N: Complement factor D
J: Fab Y49R light chain
K: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
6
Q: Complement factor D
O: Fab Y49R light chain
P: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
7
T: Complement factor D
R: Fab Y49R light chain
S: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
8
X: Complement factor D
U: Fab Y49R light chain
V: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
9
a: Complement factor D
Y: Fab Y49R light chain
Z: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,5544
ポリマ－71,4623
非ポリマー921
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
10
d: Complement factor D
b: Fab Y49R light chain
c: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,5544
ポリマ－71,4623
非ポリマー921
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
11
g: Complement factor D
e: Fab Y49R light chain
f: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
12
j: Complement factor D
h: Fab Y49R light chain
i: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
13
m: Complement factor D
k: Fab Y49R light chain
l: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
14
p: Complement factor D
n: Fab Y49R light chain
o: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
15
s: Complement factor D
q: Fab Y49R light chain
r: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
16
v: Complement factor D
t: Fab Y49R light chain
u: Fab Y49R heavy chain
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)71,6505
ポリマ－71,4623
非ポリマー1882
水543
タイプ名称対称操作数
identity operation1_555x,y,z1
単位格子
Length a, b, c (Å)263.704, 301.454, 458.842
Angle α, β, γ (deg.)90.000, 90.000, 90.000
Int Tables number23
Space group name H-MI222
Components on special symmetry positions
IDモデル要素
11c-304-

HOH

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要素

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タンパク質 , 1種, 16分子 WCFINQTXadgjmpsv

#1: タンパク質
Complement factor D / Adipsin / C3 convertase activator / Properdin factor D


分子量: 24438.807 Da / 分子数: 16 / 由来タイプ: 組換発現 / 由来: (組換発現) Homo sapiens (ヒト) / 遺伝子: CFD, DF, PFD
発現宿主: Cricetulus griseus (モンゴルキヌゲネズミ)
参照: UniProt: P00746, complement factor D

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抗体 , 2種, 32分子 LADGJORUYbehknqtMBEHKPSVZcfiloru

#2: 抗体
Fab Y49R light chain


分子量: 23354.807 Da / 分子数: 16 / 由来タイプ: 組換発現 / 由来: (組換発現) Homo sapiens (ヒト) / 発現宿主: Escherichia coli (大腸菌)
#3: 抗体
Fab Y49R heavy chain


分子量: 23668.393 Da / 分子数: 16 / 由来タイプ: 組換発現 / 由来: (組換発現) Homo sapiens (ヒト) / 発現宿主: Escherichia coli (大腸菌)

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非ポリマー , 3種, 1531分子

#4: 化合物
ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL / グリセロ-ル


分子量: 92.094 Da / 分子数: 16 / 由来タイプ: 合成 / 式: C3H8O3
#5: 化合物
ChemComp-SO4 / SULFATE ION / 硫酸ジアニオン


分子量: 96.063 Da / 分子数: 12 / 由来タイプ: 合成 / 式: SO4
#6: 水 ChemComp-HOH / water


分子量: 18.015 Da / 分子数: 1503 / 由来タイプ: 天然 / 式: H2O

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詳細

研究の焦点であるリガンドがあるかN
Has protein modificationY

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実験情報

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実験

実験手法: X線回折 / 使用した結晶の数: 1

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試料調製

結晶マシュー密度: 3.99 Å3/Da / 溶媒含有率: 69.15 %
結晶化温度: 277 K / 手法: 蒸気拡散法, シッティングドロップ法 / pH: 5 / 詳細: 0.1 M sodium citrate pH 5.0, 8% PEG 8000

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データ収集

回折平均測定温度: 100 K / Serial crystal experiment: N
放射光源由来: シンクロトロン / サイト: APS / ビームライン: 17-ID / 波長: 1 Å
検出器タイプ: DECTRIS PILATUS 6M / 検出器: PIXEL / 日付: 2015年11月14日
放射プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長波長: 1 Å / 相対比: 1
反射解像度: 3.001→251.945 Å / Num. obs: 359723 / % possible obs: 99.7 % / 冗長度: 6.8 % / Biso Wilson estimate: 55.29 Å2 / CC1/2: 0.996 / Rmerge(I) obs: 0.142 / Rpim(I) all: 0.059 / Rrim(I) all: 0.154 / Net I/σ(I): 12.9 / Num. measured all: 2447451
反射 シェル

Diffraction-ID: 1

解像度 (Å)冗長度 (%)Rmerge(I) obsNum. measured allNum. unique obsCC1/2Rpim(I) allRrim(I) allNet I/σ(I) obs% possible all
3.001-3.0116.80.8861750325730.7690.3640.9592.370.7
13.927-251.9456.40.0332463238430.9990.0140.03636.298.9

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解析

ソフトウェア
名称バージョン分類
PHENIX1.12-2829_final精密化
Aimlessデータスケーリング
PDB_EXTRACT3.25データ抽出
XDSデータ削減
PHASER位相決定
精密化構造決定の手法: 分子置換
開始モデル: prior

解像度: 3.01→49.933 Å / SU ML: 0.32 / 交差検証法: THROUGHOUT / σ(F): 1.89 / 位相誤差: 22.57
Rfactor反射数%反射
Rfree0.2148 2180 0.61 %
Rwork0.1738 --
obs0.174 357125 99.88 %
溶媒の処理減衰半径: 0.9 Å / VDWプローブ半径: 1.11 Å
原子変位パラメータBiso max: 266.7 Å2 / Biso mean: 66.8256 Å2 / Biso min: 7.61 Å2
精密化ステップサイクル: final / 解像度: 3.01→49.933 Å
タンパク質核酸リガンド溶媒全体
原子数78960 0 156 1503 80619
Biso mean--83.82 49.46 -
残基数----10464
拘束条件
Refine-IDタイプDev ideal数
X-RAY DIFFRACTIONf_bond_d0.00280944
X-RAY DIFFRACTIONf_angle_d0.533110168
X-RAY DIFFRACTIONf_chiral_restr0.04312416
X-RAY DIFFRACTIONf_plane_restr0.00414240
X-RAY DIFFRACTIONf_dihedral_angle_d11.83648720
LS精密化 シェル

Refine-ID: X-RAY DIFFRACTION / Rfactor Rfree error: 0

解像度 (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection Rwork% reflection obs (%)
3.01-3.07510.3091260.267422049100
3.0751-3.14660.30211390.240322040100
3.1466-3.22530.26761350.242722012100
3.2253-3.31250.27451260.221722142100
3.3125-3.410.24441440.205622065100
3.41-3.520.23781220.198322109100
3.52-3.64580.27141350.195122097100
3.6458-3.79170.24061500.185222123100
3.7917-3.96420.21611420.167622149100
3.9642-4.17310.18811590.150122160100
4.1731-4.43440.17551220.135122182100
4.4344-4.77650.15671440.128422190100
4.7765-5.25670.20381320.13122267100
5.2567-6.01630.18351260.154622336100
6.0163-7.57560.22491290.177722422100
7.5756-49.9330.18491490.1782260299
精密化 TLS

手法: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.0067-0.00710.00210.00450.0010.00950.0661-0.00140.0246-0.0256-0.0546-0.0217-0.0158-0.0482-00.41990.0178-0.01610.27330.05390.3451-65.8189-8.2639-24.7884
20.0572-0.04280.03210.037-0.0370.03840.0660.2061-0.0436-0.1324-0.0543-0.1781-0.00310.07560.00170.2103-0.0078-0.02080.12380.02550.1497-54.1745-20.5379-24.969
30.0294-0.00960.00260.02790.01690.0095-0.03360.11210.05340.0724-0.0005-0.1505-0.02090.0769-0.00010.2667-0.06290.00550.17750.00370.1631-50.5078-17.0461-16.6306
40.00260.0072-0.00450.05630.02730.08-0.0922-0.0002-0.01410.0555-0.0184-0.0194-0.1297-0.0352-0.05760.3762-0.0532-0.01580.2097-0.08240.1892-59.5463-5.2783-7.8761
50.00580.00320.00530.00410.00250.00340.04960.0481-0.06630.01280.00130.06850.0416-0.006700.34210.0052-0.00380.3041-0.03930.2129-71.3177-19.7419-23.8517
60.00490.01040.00670.00810.00610.00370.0025-0.08030.0329-0.00830.0126-0.07670.0040.004400.2594-0.0133-0.01020.1617-0.01250.1697-66.3998-13.7663-2.5143
70.0022-0.0005-0.0026-0.0006-0.00050.0058-0.0278-0.0334-0.07180.02780.0459-0.0304-0.0294-0.1137-00.46370.0750.02280.2748-0.06710.2642-70.5873-15.4604-13.4488
80.0105-0.0037-0.02220.09040.070.1456-0.03250.02570.05390.0024-0.0442-0.0190.0056-0.0669-0.1020.35090.05-0.06440.10630.04150.1965-65.827-14.7236-10.142
90.00060.0041-0.00480.0165-0.02060.0350.0479-0.0110.05240.0660.0392-0.0437-0.04460.00530.02150.2413-0.0254-0.07130.1384-0.03040.291-49.8878-14.1199-8.8469
100.08060.0458-0.06330.0364-0.01360.07780.05680.0071-0.0420.2543-0.01420.159-0.0322-0.16520.00290.4046-0.00890.05280.1699-0.0330.1943-78.1861-32.522715.3384
110.23060.0070.10720.0649-0.01160.0626-0.0782-0.05830.00470.0944-0.16240.12810.0011-0.0528-0.1970.5978-0.06510.14380.2737-0.05730.2481-82.502-31.282122.6486
120.0314-0.0404-0.00250.0630.02490.04330.06110.07360.01670.0939-0.00840.1514-0.0077-0.01170.00661.283-0.1380.36710.708-0.13630.565-87.665-31.841951.1354
130.00260.00140.00260.0010.00160.00210.0373-0.01560.0172-0.04740.00340.04630.0204-0.014500.8583-0.11120.30720.67080.0020.7185-95.4527-27.616548.112
140.0003-0.0013-0.00130.0168-0.01460.01210.0922-0.055-0.02640.0261-0.01720.04610.0291-0.017600.9393-0.03130.27550.50970.03020.5016-84.9397-31.177947.1368
150.00140.0026-0.0030.0041-0.00470.00580.00260.0383-0.08270.10730.0030.0083-0.0857-0.013201.2187-0.10750.56570.8534-0.05140.9013-94.9886-36.537654.2183
160.3663-0.08760.2530.0414-0.06860.185-0.0124-0.0130.15570.3056-0.06540.05430.11940.0557-0.07870.4546-0.04060.03810.1924-0.04890.1792-71.9126-11.125222.8113
170.0033-0.00190.01080.0189-0.00130.03230.0684-0.02570.03170.06410.0546-0.0370.04250.01030.04241.3867-0.10870.21810.6336-0.10780.3782-76.7925-27.115652.7412
180.0575-0.02820.00410.07850.00420.00480.0845-0.15410.0567-0.00680.063-0.0081-0.09210.05590.05321.1735-0.1066-0.00850.6003-0.04160.2619-73.4412-28.803953.1148
190.0056-0.0049-0.00420.00160.0030.00540.0674-0.0354-0.0002-0.06380.08210.03590.04470.0356-00.4085-0.0453-0.1010.21320.01170.3036-56.2122-142.4301-24.6901
200.12610.0771-0.05340.2778-0.13720.0726-0.1380.0536-0.0075-0.0175-0.09520.0715-0.029-0.0539-0.07210.3589-0.0758-0.0210.1175-0.03350.1702-65.2922-130.6581-23.6028
210.19040.0283-0.08750.00960.00050.0850.05030.0909-0.0274-0.03120.01350.0126-0.1009-0.0998-0.00770.2422-0.0177-0.05240.1010.02940.2746-69.7236-127.3105-21.0165
220.00620.00160.00490.10730.01080.0047-0.02380.02230.04760.00980.03610.2160.08770.0447-0.00090.2828-0.0366-0.0680.19530.01550.172-68.0738-130.0889-20.7079
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1400.00410.002-0.00160.0029-0.00270.0030.0636-0.04760.13650.0222-0.0131-0.0085-0.08420.113200.6223-0.2269-0.07760.602-0.1380.6223-6.9887-11.317-69.2411
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1420.00510.00230.00270.0218-0.00640.0092-0.0185-0.05150.0590.0696-0.13260.0406-0.0364-0.0262-0.01870.41-0.1970.15460.555-0.05740.3825-15.4047-12.0678-81.5078
1430.00260.0040.00130.00580.00320.00430.10910.00150.00590.09370.06420.0413-0.06560.016400.7122-0.23310.02870.6168-0.05680.6505-9.7772-7.5751-82.2477
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1450.07850.043-0.00770.0233-0.00320.00070.0757-0.01130.01430.02390.01580.00610.03230.08230.02160.3415-0.1947-0.05710.5804-0.07030.2666-13.8123-20.2347-75.0794
1460.0633-0.0104-0.06130.07370.02140.06-0.0256-0.0312-0.02650.1826-0.06320.03540.0087-0.00470.00520.9109-0.4590.09010.6645-0.18840.539-16.6732-4.7752-48.7468
1470.0010.00230.00440.01410.01390.0144-0.0046-0.00740.01040.0941-0.0014-0.07670.03130.0391-01.3216-0.43890.12660.9646-0.10540.7615-17.8311-9.4725-46.427
1480.0011-0.00040.0009-0-0.00010.00110.0053-0.0111-0.00960.0010.0143-0.032-0.00960.023201.1618-0.0025-0.07350.88630.11680.836-19.4741-20.9008-42.3763
1490.00120.00060.00170.00220.00070.00320.0034-0.02550.00160.00180.00950.00210.0001-0.02501.1184-0.24880.03450.9653-0.11760.8525-21.059-2.8439-53.8327
1500.00160.00340.00070.00510.00270.007-0.0216-0.0042-0.0053-0.04510.0404-0.0133-0.03150.020601.0832-0.1463-0.07630.79310.09860.6869-25.0548-16.5633-37.5274
1510.00470.00410.00220.00340.00230.0051-0.05480.00110.05820.0280.0032-0.03580.00310.0016-01.3994-0.1888-0.06641.29150.01141.1833-15.5617-15.1415-36.8151
1520.0002-0.0003-0.0024-0.00050.00020.0019-0.0037-0.03760.00390.04680.0069-0.05920.0031-0.0253-01.1831-0.0703-0.18191.1583-0.06631.0148-12.4173-8.8409-39.2337
1530.0732-0.0339-0.00150.01580.0020.0059-0.03490.02680.0191-0.03220.04180.02750.00610.0059-0.0230.465-0.1722-0.32730.6382-0.00070.4793-108.3885-117.8351-120.0856
1540.03840.00740.03080.0253-0.01280.02930.05870.09480.0826-0.07740.06680.1478-0.0043-0.07650.2927-0.0256-0.0972-0.36650.50840.06280.3306-108.615-102.155-113.8265
1550.0157-0.00640.00570.0071-0.00460.01520.0411-0.01910.0366-0.02020.05910.05120.0586-0.06960.08840.2172-0.0655-0.24820.43410.080.4859-115.2501-105.0538-107.1051
1560.02370.0385-0.02070.0669-0.04060.02140.05190.03160.02080.00780.01940.09280.0754-0.05770.03680.2753-0.1371-0.17990.55370.02540.4174-118.2903-121.758-104.9912
1570.00490.0007-0.00580.00230.00050.00590.0202-0.003-0.0003-0.06480.0554-0.0297-0.0232-0.02830.00010.426-0.1014-0.16130.5841-0.00890.4719-96.928-114.5836-115.3605
1580.0673-0.0331-0.0040.0340.01490.0117-0.06030.0290.0387-0.01330.05990.05350.00290.0307-0.01090.0738-0.1339-0.12610.5032-0.05490.2641-108.4381-123.2248-97.8664
1590.0025-0.00460.00070.0037-0.00220.00160.01250.018-0.00420.00040.0196-0.01090.05020.076-00.4047-0.0712-0.18940.50070.00070.5047-102.4217-120.8788-107.5576
1600.0060.0053-0.00750.0067-0.00760.0091-0.01920.02880.003-0.0190.04690.0290.0539-0.01160.01310.2277-0.0863-0.16520.584-0.07040.31-106.9466-119.375-104.2589
1610.0152-0.00650.00110.01260.00430.00170.0131-0.0115-0.0083-0.02270.01270.02590.0151-0.02560.03450.1678-0.0913-0.11260.44180.02620.3254-118.9818-109.3402-101.1956
1620.04250.0359-0.01450.0862-0.06450.0520.0322-0.0065-0.07520.1414-0.0654-0.0205-0.0090.0055-0.07520.0224-0.1767-0.13490.2348-0.11710.0659-90.6592-125.1647-75.6516
1630.1386-0.039-0.04290.27610.11720.0616-0.08680.0616-0.11460.1879-0.094-0.03110.0188-0.0235-0.21260.37-0.2251-0.07630.38410.10450.2627-92.449-137.8733-57.4221
1640.005-0.00060.00870.0006-0.00040.01390.04620.0686-0.0168-0.0046-0.0034-0.04540.03720.024500.7924-0.0946-0.04810.6470.14440.387-86.4561-141.9757-47.5208
1650.0744-0.0197-0.02760.01190.00040.01040.1133-0.0328-0.00890.1311-0.0527-0.07130.16630.0770.02950.7515-0.0963-0.13060.5710.18810.4174-87.1644-145.6816-44.2947
1660.2070.01550.21360.2241-0.0250.2204-0.1185-0.06650.01050.0468-0.07490.05510.09970.0146-0.18480.2694-0.07140.18030.265-0.05450.3821-114.0457-138.9531-70.4437
1670.02080.0261-0.00210.05280.0070.01370.0666-0.01470.04150.1618-0.08220.0795-0.0432-0.0616-0.00060.2015-0.0914-0.01570.3548-0.02120.3123-108.6583-134.6009-79.1906
168-0-0.0016-0.00360.00530.00630.009-0.06150.03420.0060.023-0.0699-0.0095-0.0069-0.00850.00010.3019-0.1092-0.04630.4613-0.07460.3675-107.4155-142.557-86.7238
1690.02020.0076-0.01080.0034-0.00020.01660.06290.10530.02770.0583-0.0360.04650.0589-0.12460.02480.2299-0.10820.08630.381-0.06040.3459-111.5355-140.3002-77.7842
1700.10570.01870.07410.02860.06680.1733-0.1069-0.0814-0.05260.0518-0.11630.10070.06690.0065-0.27510.2126-0.14780.10750.3375-0.01970.2809-108.936-138.6785-67.2752
1710.0040.0022-0.00590.0036-0.00180.0075-0.0998-0.0137-0.00390.0409-0.001-0.02780.0309-0.023601.029-0.26980.00940.87670.06940.4765-98.5235-140.9612-38.4698
1720.00010.0018-0.00260.0033-0.00450.0054-0.0559-0.06750.03190.01190.00490.02530.0053-0.0200.8724-0.13720.10750.7087-0.11780.6377-107.5148-139.1628-49.5079
1730.0222-0.0027-0.00260.0083-0.01150.0156-0.024-0.0952-0.08980.03710.09710.06660.001-0.0518-00.7242-0.12210.11910.579-0.06790.3882-99.1626-138.0919-46.4325
1740.00650.0014-0.0033-0.00050.00020.00320.00870.0203-0.05130.05430.01390.0873-0.013-0.02300.7665-0.0740.1051.032-0.10260.7639-108.0846-136.1379-40.7444
1750.0014-0.00110.00130.00010.00170.0031-0.0073-0.0198-0.01630.038-0.03740.0145-0.00930.0186-00.9652-0.06450.24281.0749-0.02730.775-107.8903-141.1365-37.0579
1760.00070.0039-0.00080.0265-0.0150.0108-0.0101-0.01140.00960.0245-0.0475-0.0766-0.0122-0.0044-0.0080.3411-0.0418-0.16330.17790.03230.2773-36.4681-82.5179-2.5716
1770.0041-0.015-0.00770.05520.01910.0103-0.0555-0.02830.06410.1131-0.0568-0.0945-0.05620.1857-0.29110.2082-0.0058-0.35630.15980.07680.0121-35.169-95.25038.4307
1780.0152-0.01410.02110.0146-0.0180.0314-0.1008-0.08030.09280.15310.03950.0063-0.09630.120300.3905-0.0459-0.11710.2224-0.0030.2874-43.4747-92.345212.726
1790.0036-0.00790.00480.0088-0.00830.00790.01360.02630.15460.0996-0.00270.110.06360.0528-00.34990.0338-0.09040.2105-0.0450.3563-53.2296-80.47014.549
1800.00150.0031-0.0050.0325-0.04090.03940.0459-0.07340.02320.0650.06440.03980.0572-0.0750.00120.2084-0.0225-0.08190.1540.0120.2484-45.0958-89.3004-6.4871
1810.0156-0.0159-0.00230.01510.01210.004-0.20350.0990.07010.16180.02120.04140.02780.0227-0.00410.2852-0.0056-0.07230.21150.01810.2132-55.9761-91.1942-3.7229
1820.0219-0.001-0.0177-0.00030.00170.0214-0.0630.1202-0.0404-0.00330.0680.0083-0.0326-0.10210.00130.254-0.0688-0.08170.1524-0.00090.2117-50.8155-89.4679-2.2521
1830.0044-0.0004-0.00030.00210.00390.0037-0.04520.01820.01120.0508-0.01020.0965-0.0043-0.036300.48430.026-0.00880.1716-0.01360.1845-51.3526-89.786713.7404
1840.0577-0.03860.04330.12940.030.17350.01580.0708-0.16630.0949-0.05820.3106-0.03290.0027-0.07230.1835-0.0427-0.03590.0697-0.04970.3556-82.5048-107.7452-15.1979
1850.10920.0221-0.02320.0048-0.00150.0496-0.06660.0374-0.1195-0.0544-0.12180.0576-0.0324-0.0544-0.19860.3685-0.0791-0.27170.4765-0.14741.3086-111.9462-111.209-22.5138
1860.0583-0.00430.00950.1473-0.00510.07470.0316-0.0171-0.07190.14150.01680.208-0.09510.00810.00710.1795-0.05260.00950.16980.02390.3292-84.3031-87.5548-6.8041
1870.00230.0017-0.00070.00850.00120.0016-0.0328-0.03830.01510.1212-0.1160.10050.1093-0.1144-0.11090.4753-0.20310.15360.41390.09871.1151-110.2796-107.1922-8.1101
1880.00090.0009-0.002500.00040.0010.0718-0.04990.0014-0.00630.0713-0.0039-0.07160.043-00.9606-0.26270.27640.795-0.01811.1221-115.326-106.4672-0.4864
1890.00440.00310.00310.00340.00030.00230.00180.00170.00060.0503-0.04850.0820.0265-0.014600.6006-0.09880.14120.3374-0.00390.3873-85.6793-68.1429-2.742
1900.00550.01150.00910.0140.01110.00760.05190.06330.06340.0459-0.08060.1153-0.0472-0.142100.3709-0.02880.05410.2562-0.0250.2629-84.1895-53.85158.3434
1910.00360.00180.00370.0128-0.01320.0068-0.0399-0.04330.01830.00190.0118-0.02550.0008-0.093800.3238-0.04090.090.2919-0.01370.2785-92.0154-58.11268.039
1920.0174-0.0113-0.00170.00730.00620.0399-0.0028-0.0371-0.08540.0741-0.0579-0.03050.0692-0.113700.4371-0.05120.06530.30960.01670.3119-78.7964-58.369212.5548
1930.0039-0.0036-0.0040.0024-0.0010.0104-0.03620.0312-0.13450.15260.0596-0.02830.0193-0.0322-00.3501-0.01860.07010.15720.00460.26-68.9599-70.20764.4171
1940.0032-0.00360.00390.0036-0.00340.0026-0.08040.0574-0.0004-0.0398-0.09430.0247-0.06130.0480.00010.4415-0.01770.10710.2016-0.03260.3752-84.8481-56.937-8.7712
1950.00230.00560.00470.0070.0060.0036-0.01340.011-0.05090.17750.0692-0.0176-0.00520.087900.2905-0.00980.01750.2014-0.00260.1975-63.659-61.7918-2.552
1960.00450.00060.0020.0039-0.00170.0032-0.07070.0321-0.01910.0427-0.0085-0.0598-0.017-0.001600.36360.02390.11110.3523-0.02150.3525-74.3466-60.8246-7.2544
1970.01150.00560.01110.00340.00520.0087-0.06960.1196-0.0185-0.05170.02270.0936-0.03350.0738-00.3621-0.107-0.00330.24110.01960.2569-71.3415-61.2468-2.3639
1980.07760.0057-0.02710.0009-0.00590.0881-0.011-0.0478-0.04990.0460.0045-0.00180.01290.00030.00810.48740.00010.04480.12520.00680.1444-70.8901-60.912413.6337
1990.08550.01370.03080.0115-0.00280.0176-0.02180.1730.10310.0048-0.07230.01050.0524-0.0569-0.01230.2707-0.0056-0.04380.2128-0.06050.2125-42.6839-40.5296-20.7649
2000.02490.0237-0.02370.0286-0.02630.01850.0210.05610.14550.04630.0256-0.05190.10470.0163-00.2559-0.0301-0.07280.17690.01340.2452-47.1972-43.1277-13.0302
2010.00130.003-0.00960.0064-0.00780.15880.03630.05450.07-0.1229-0.0243-0.20550.041-0.0402-0.00920.18390.01690.00480.15530.01950.4587-24.4914-43.7445-18.9043
2020.0053-0.00540.00620.0013-0.0020.0093-0.09850.0884-0.0115-0.11840.0169-0.09020.0918-0.044100.4755-0.00160.06790.53010.07130.8175-15.4594-38.8795-24.923
2030.0016-0.003-0.0010.00140.00130.002-0.02380.0480.0183-0.0422-0.0001-0.0111-0.00880.0419-00.401-0.09130.19910.45950.020.5275-12.4439-45.8879-30.2939
2040.0014-0.0005-0.00190.00040.00060.0017-0.0444-0.01080.00240.0205-0.049-0.0103-0.01650.004700.4867-0.0113-0.11850.50130.04130.4999-24.4354-33.7978-13.464
2050.01050.00680.0210.00420.0150.0413-0.00370.0128-0.0058-0.0356-0.06710.0018-0.0180.015-0.04230.59640.00670.43730.6339-0.06121.0082-5.84-44.4754-28.6698
2060.00770.003-0.00350.0004-0.00170.0046-0.03360.007-0.0745-0.0288-0.0214-0.1293-0.0469-0.102700.869-0.08810.24851.00080.18821.102-7.6828-33.543-29.3616
2070.0380.0103-0.0360.0188-0.02630.05710.0567-0.0323-0.01970.05070.0195-0.07450.0221-0.00960.0560.26360.0143-0.14090.2627-0.07430.3044-31.3722-62.8967-2.6995
2080.07730.03880.08670.0290.04660.124-0.0298-0.06390.18220.0866-0.0798-0.18510.09480.0217-0.07320.2489-0.0561-0.06440.12690.05550.2263-43.4804-62.5065-6.6085
2090.00370.0090.00180.01660.00750.00460.0043-0.03590.03040.00160.0072-0.1034-0.0124-0.0223-00.31970.0061-0.07940.2544-0.08240.3663-41.3197-70.0385-9.0306
2100.117-0.05230.03070.2230.04870.06460.04380.11960.01050.1298-0.029-0.29870.06090.0198-0.02750.1809-0.0508-0.2040.1225-0.05270.4188-27.6978-57.5688-8.9883
2110.005-0.00580.00940.0124-0.0180.01750.0018-0.0403-0.00560.01910.0181-0.04060.0073-0.03290.00740.28290.0122-0.25890.3796-0.08091.0432-11.4149-46.7671-9.9252
2120.0075-0.0037-0.00730.00340.0050.0046-0.1620.0681-0.07270.0895-0.0552-0.0309-0.1490.036-0.00050.35380.0698-0.21890.4156-0.12440.8098-14.5967-45.3821-11.2463
2130.005-0.0026-0.01220.00120.00620.03660.01590.0099-0.0023-0.0109-0.00670.0044-0.07890.04610.00510.4578-0.0756-0.30120.4715-0.12151.0527-8.2831-33.7387-11.2975
2140.0143-0.010.00980.0065-0.00660.00510.0054-0.0102-0.0259-0.0130.01590.01770.03650.0589-00.66210.1072-0.43110.65460.01241.1532-4.8692-39.2556-4.3425
2150.02210.0068-0.03930.0121-0.01040.0640.03740.05940.00830.01230.0316-0.0144-0.02360.0650.00540.5032-0.0883-0.3340.64630.01691.0751-3.6495-46.5652-5.5678
2160.0367-0.0104-0.02320.009-0.01270.08550.0311-0.0016-0.0007-0.07330.0407-0.0462-0.0052-0.05290.03410.26-0.03930.10450.17940.03720.136-55.7754-51.332-37.894
2170.0178-0.01060.01180.00660.00090.0124-0.0370.05660.0749-0.0344-0.10360.1039-0.09320.035200.19370.02870.00880.2192-0.00650.1481-65.9613-36.8682-42.1316
2180.0231-0.03120.01150.0516-0.03160.0296-0.0370.042-0.04230.0268-0.0489-0.0951-0.1201-0.0357-0.00210.3318-0.008-0.01250.22720.0120.1498-57.1464-36.1017-42.679
2190.01180.01210.01740.0455-0.01980.043-0.0310.0606-0.03950.0233-0.02070.03830.03160.0818-00.1622-0.00370.0140.30710.01170.1316-68.6261-41.3079-48.4203
2200.02560.02730.01930.02440.02010.0330.08510.036-0.0645-0.05510.01730.00410.06690.03110.06490.4139-0.16550.01480.3316-0.14550.2055-69.7076-58.4096-47.6276
2210.005500.00330.00270.00410.0047-0.07730.06990.01110.03110.0260.0326-0.03080.0274-00.2830.01070.05320.25990.00630.1247-61.6496-45.9369-27.9058
2220.0103-0.0017-0.01290.00020.00160.01310.07260.0265-0.0387-0.0931-0.03490.033-0.01710.02220.00080.2653-0.0865-0.01090.2959-0.10320.2274-70.9266-59.6331-37.7949
2230.01840.014-0.0110.0792-0.01940.0101-0.1031-0.0636-0.0202-0.0267-0.1451-0.0304-0.006-0.1137-0.0090.2617-0.065-0.01590.3609-0.0150.1551-76.5811-55.5888-35.7813
2240.2487-0.0731-0.00240.0406-0.01110.00560.0038-0.0458-0.1136-0.07560.10880.0074-0.03930.00280.02310.17590.03860.04310.2957-0.05660.1272-71.6014-53.557-37.28
2250.0065-0.00560.00030.00760.00020.0006-0.02750.0827-0.0121-0.08870.00770.0169-0.02830.033-0.02270.24560.0403-0.05560.386-0.0520.0934-73.9247-46.904-51.4127
2260.00660.0114-0.01880.018-0.04470.1581-0.0338-0.06730.02440.0461-0.06090.21920.00660.0529-0.05920.1207-0.05870.04070.2986-0.09370.4272-99.543-60.0754-17.6667
2270.0232-0.0129-0.02130.0194-0.00110.0211-0.02350.07830.08070.0780.01410.11770.0505-0.1159-00.2191-0.0028-0.01270.3701-0.07030.4055-99.6493-54.4794-25.1067
2280.01150.01850.00850.02360.01680.0049-0.0488-0.0443-0.02870.0262-0.08320.01770.2637-0.185400.3299-0.05760.03580.4252-0.09370.4227-100.8474-61.2328-23.1289
2290.0139-0.0147-0.00190.051-0.01050.0010.01470.07120.02630.00240.0372-0.02210.0614-0.05720.00750.2636-0.19850.08750.6266-0.16950.9492-130.7594-73.6035-20.9837
2300.0386-0.0524-0.04670.07370.0640.0572-0.1354-0.04020.00430.0355-0.0551-0.01970.07580.02870.00350.5649-0.28850.18020.6566-0.23611.094-128.5775-73.631-14.846
2310.0093-0.00570.00070.0027-0.0005-0.0007-0.1650.0267-0.02070.0008-0.06440.0340.03680.001-00.623-0.11620.08050.8283-0.03941.0699-125.6641-72.8055-17.6317
2320.0102-0.0014-0.00450.0076-0.00180.01060.0610.0265-0.03740.07840.01960.0482-0.0857-0.01800.8058-0.3760.33890.9259-0.18351.6294-135.2482-81.6336-13.8479
2330.0439-0.0089-0.00680.01980.00710.0027-0.11520.0727-0.02440.0266-0.06090.06060.0823-0.0934-0.05950.5306-0.2724-0.05030.5557-0.23970.4843-103.8249-76.3322-41.5852
2340.2213-0.05340.01910.1883-0.24680.3454-0.20910.1514-0.01820.0343-0.09650.16170.04930.0373-0.11040.399-0.24430.15590.4644-0.20120.4811-95.76-70.3353-36.6697
2350.00270.00240.00410.00390.00490.0068-0.03150.0467-0.0890.0241-0.03820.03940.02510.0073-00.6615-0.09540.16760.4338-0.06940.6247-88.1465-77.4234-32.7763
2360.25590.05830.17340.22130.12650.2002-0.15270.088-0.06890.0401-0.08820.21080.1201-0.1356-0.49790.4168-0.43070.16990.4823-0.33440.5325-100.7807-76.0611-37.6629
2370.00640.00340.00470.00440.00370.0031-0.00620.014-0.0193-0.02190.0295-0.00240.0117-0.0054-01.2407-0.3503-0.23291.4182-0.26511.5074-136.8085-76.6529-27.8075
2380.0014-0.00150.00010.0006-0.0006-0.00030.00390.0518-0.0325-0.0380.0561-0.0272-0.02-0.020401.1839-0.40150.19911.3079-0.23431.2114-125.1481-76.1823-36.306
2390.00980.0043-0.00370.00330.0010.0031-0.0542-0.0185-0.0701-0.0322-0.0378-0.0401-0.0069-0.063700.9203-0.2309-0.00310.9023-0.25251.2019-124.5136-75.7845-28.8901
2400.0121-0.00370.00020.00510.00180.0006-0.00440.0237-0.0033-0.01390.0279-0.0004-0.0047-0.010100.9105-0.1355-0.14561.0053-0.13051.0749-137.4178-68.9197-27.8184
2410.00260.0040.00420.00510.0060.00570.00960.0052-0.0074-0.02970.0266-0.00680.0342-0.0123-01.6092-0.1118-0.19881.7581-0.26981.7279-137.2783-72.399-36.8567
2420.00460.00570.0040.00560.00480.00410.02130.0143-0.0146-0.05990.02970.01480.02280.0125-01.5725-0.2606-0.08181.7148-0.29461.6481-134.3498-79.2779-38.1796
2430.0032-0.0029-0.0030.00640.00130.00230.0687-0.02560.0547-0.04490.02250.0316-0.03630.0081-00.35120.0142-0.09630.25960.01950.2597-66.077-99.2948-37.7997
2440.0164-0.00940.02710.0152-0.00910.10790.01350.0247-0.02440.0064-0.05280.05840.0664-0.0012-0.14370.246-0.0848-0.19750.1314-0.00730.1232-59.0562-113.9918-42.2255
2450.0178-0.00410.02040.04020.0030.0354-0.01320.0410.03740.0203-0.01350.00580.0693-0.057-0.05880.2298-0.0474-0.11980.24920.03160.1585-53.1213-109.247-48.2301
2460.0681-0.036-0.01420.02120.0090.00430.00460.02380.1222-0.0210.02530.0045-0.013-0.0097-0.01660.3528-0.1333-0.13430.21250.09580.2556-52.0039-92.2173-47.425
2470.0599-0.00350.06730.0118-0.01190.083-0.029-0.05070.02230.07580.0353-0.0083-0.02650.00720.03390.3210.0207-0.16150.17390.03690.2333-60.332-104.744-27.793
2480.08030.03420.05130.023800.1007-0.0307-0.01630.0606-0.0332-0.06520.0013-0.01320.0115-0.18410.2273-0.0348-0.13350.18970.04590.1829-44.2367-92.5169-37.8638
2490.02020.01360.01610.01530.00140.025-0.0328-0.01860.0461-0.0297-0.0352-0.00380.0472-0.0116-0.02250.4016-0.1028-0.17070.3302-0.00720.338-53.3006-96.972-32.037
2500.01220.0080.01160.0366-0.00510.0349-0.0084-0.06230.04720.02760.06630.00940.0202-0.02020.07040.12540.0238-0.11990.25510.09060.1243-50.2372-97.076-36.992
2510.0019-0.0030.00610.0067-0.01210.0232-0.00520.02480.0163-0.03490.01710.0187-0.0002-0.01660.05130.2505-0.0315-0.10920.2290.0370.1462-47.7248-103.697-51.1413
2520.02150.02430.04290.12540.04450.0719-0.0489-0.03290.13960.07190.0456-0.1893-0.00310.0176-0.01520.108-0.0013-0.15620.24180.04520.3431-22.4031-93.2553-20.9022
2530.01820.0425-0.0270.1287-0.03070.0879-0.0448-0.00240.10170.1502-0.1182-0.285-0.12010.061-0.14770.1898-0.0169-0.33550.24610.0980.4058-14.2338-89.7052-20.3417
2540.01270.00170.00220.0028-0.00350.0016-0.01070.0055-0.0867-0.0277-0.026-0.0124-0.0407-0.013-01.0605-0.1904-0.10531.52850.17211.801915.1004-65.2982-25.3783
2550.0261-0.04170.01460.0691-0.02620.0107-0.0195-0.03840.01780.0537-0.0495-0.0364-0.0244-0.0401-0.0360.6501-0.1925-0.50390.65210.14141.09056.2749-76.8255-14.2119
2560.0093-0.00580.00570.0052-0.00640.0066-0.1371-0.0119-0.0060.0164-0.0774-0.0337-0.06020.0627-00.552-0.1145-0.2280.59790.05840.89343.5228-77.7042-17.0771
2570.0213-0.0121-0.04770.00650.0260.12230.14150.0105-0.0476-0.03080.09960.0215-0.02720.03560.03070.6869-0.2816-0.42470.90630.0511.48611.7064-61.6602-17.5327
2580.0118-0.00180.00830.0044-0.00290.00480.03990.01490.07450.02510.0411-0.07310.06080.047901.1866-0.4131-0.66340.98060.04671.603813.9616-74.026-10.1331
2590.0156-0.0142-0.00780.01240.0080.0071-0.07590.14430.0821-0.0086-0.050.0021-0.07260.0388-0.01540.5824-0.2522-0.16260.51810.23180.548-17.8991-74.3523-41.1581
2600.1239-0.07-0.07180.10240.11380.127-0.13330.11160.1625-0.0767-0.1044-0.0468-0.0688-0.0564-0.16840.3448-0.1804-0.25310.36850.13440.4547-27.2639-81.6245-40.1094
2610.0117-0.002-0.00640.0070.00960.0140.0053-0.00590.01610.0143-0.0756-0.0089-0.07810.0033-0.0320.3477-0.0387-0.25880.34560.0860.4268-29.2539-77.6438-32.0359
2620.0180.0028-0.00210.0036-0.00430.0051-0.0730.05970.03630.02180.0051-0.0265-0.0222-0.023100.5685-0.2215-0.23290.49270.18680.6393-30.6077-72.0422-36.2076
2630.01670.01390.02320.00970.01810.0288-0.0221-0.00390.1640.04120.0273-0.0523-0.05820.01530.04790.4618-0.2345-0.3160.46990.15750.7454-22.8386-68.9691-35.5709
2640.1270.0487-0.08520.11030.00810.0793-0.08030.0981-0.09080.0344-0.11980.0313-0.026-0.0195-0.08030.2343-0.1438-0.11760.34830.10650.376-22.8209-84.9564-36.1253
2650.0931-0.02660.05430.073-0.06810.07220.0465-0.0264-0.0113-0.0238-0.02610.0199-0.02320.04620.01450.666-0.3443-0.14560.50010.25290.9221-8.0276-65.8116-35.8588
2660.00560.00260.0010.0051-0.00130.00090.02520.0061-0.00270.00750.0134-0.02370.00540.0032-01.1489-0.21490.05761.19830.25371.581114.8527-74.2622-27.2929
2670.00470.002-00.0007-0.0001-0.001-0.05340.04360.0379-0.0603-0.01110.01850.04560.054800.9964-0.3562-0.02651.00840.18521.15364.3703-75.9349-35.7521
2680.00470.0038-0.00220.0029-0.00160.0005-0.0578-0.02760.0173-0.0226-0.0362-0.0221-0.0679-0.024600.7245-0.1682-0.02110.73490.0911.10421.647-73.776-27.5292
2690.0111-0.0012-0.00060.0057-0.0016-0.00020.01940.01090.00630.00670.03890.02850.03340.0458-00.7543-0.10210.12690.94760.07211.234715.4535-81.8675-27.2097
2700.00610.0014-0.00220.0051-0.00710.00620.01980.0069-0.0033-0.01860.02480.0127-0.04350.011301.5614-0.02380.25941.52710.23031.632315.3604-78.5396-36.2471
2710.00270.004-0.00160.0051-0.00450.00260.03970.00890.0129-0.02670.0635-0.02520.0027-0.00801.4894-0.09230.09851.4910.32231.558912.5316-71.756-37.8277
2720.00280.00060.0035-0.00050.00090.0041-0.03290.0402-0.04190.0767-0.07510.0898-0.05060.0286-00.45530.01560.14640.4772-0.04770.5558-101.2655-25.37663.953
2730.0065-0.00280.00380.00220.0040.01680.008-0.0477-0.03240.0112-0.02280.01170.0013-0.0556-00.24070.00320.03730.4057-0.05570.3889-104.3388-40.5854-5.5833
2740.01460.0319-0.00240.05110.00150.01040.0983-0.13840.00820.05690.02180.1431-0.1097-0.20290.09140.19680.01820.10870.428-0.0780.4309-108.5717-38.2858-4.123
2750.01210.0059-0.00610.0051-0.00230.0006-0.0515-0.0377-0.0486-0.0927-0.09110.1062-0.15950.0096-00.37850.19660.01280.57040.08630.4942-110.4167-19.5242-10.9568
2760.0064-0.00130.00520.00270.00390.00550.01220.0268-0.00640.03740.043-0.08340.0072-0.003300.4291-0.00070.12420.3855-0.06230.4236-90.7369-30.7129-0.898
2770.0087-0.0065-0.00320.00310.00010.0045-0.0410.04690.02680.0451-0.09970.1689-0.0345-0.0034-00.36870.0932-0.04090.4158-0.07550.4235-100.6315-19.8817-18.292
2780.0032-0.003100.0032-0.00120.0028-0.02530.0181-0.0719-0.006-0.03690.0264-0.05660.0455-00.45490.01020.06080.4048-0.01690.4304-94.9489-23.5165-8.6027
2790.0069-0.00530.00740.0153-0.00660.0077-0.0878-0.02480.020.0601-0.06760.1153-0.0971-0.0132-00.32220.08430.06680.4595-0.0510.3535-99.766-24.0568-11.8997
2800.00260.00060.00220.0059-0.01130.01370.02150.0146-0.0486-0.0121-0.07260.0883-0.0438-0.065-0.00010.22880.1174-0.03180.4342-0.10680.471-113.576-31.4555-14.8705
2810.0043-0.00050.0030.0112-0.00840.00540.1026-0.04660.01940.01890.0297-0.0081-0.08430.0711-0.00010.48120.0748-0.02910.2291-0.04240.2724-77.0068-18.0899-43.9729
2820.03030.0158-0.02240.03490.01080.03440.01770.0588-0.0263-0.087-0.11390.0975-0.0981-0.0061-0.06360.30240.0853-0.09870.2707-0.02830.2023-84.5582-21.6522-37.9097
2830.24230.1938-0.14510.1598-0.11990.08870.02750.02520.17390.02360.00070.091-0.07-0.00780.10420.33310.1165-0.1430.3476-0.03440.2597-84.8311-17.2077-40.9942
2840.0606-0.01030.0240.0018-0.00870.0476-0.08560.03930.0448-0.0118-0.0334-0.0291-0.0435-0.0197-0.06340.50210.07660.04740.37880.14740.2185-75.3028-19.9508-61.1988
2850.00270.0021-0.00410.0018-0.0040.00740.01370.00860.00810.0102-0.04340.01140.0126-0.0117-01.15240.1049-0.14510.91350.33470.7982-85.15372.6984-78.5736
2860.00980.0075-0.00130.00720.00450.0091-0.00780.00570.0653-0.0046-0.0278-0.0364-0.0869-0.020600.97850.0575-0.10060.67960.22260.656-75.9599-4.8028-68.6252
2870.0066-0.00430.0030.00340.00190.00910.02840.01770.00610.0030.0683-0.0237-0.01280.0927-00.90950.0904-0.15690.62570.03920.5962-78.4538-6.4501-65.8811
2880.00530.00710.00050.00740.00350.00490.00060.00280.01980.0159-0.0346-0.03350.0052-0.002901.1859-0.1462-0.20770.73240.29430.8459-76.94096.536-74.4399
2890.00720.0021-0.00310.0008-0.00220.0024-0.01710.0044-0.0246-0.0440.0018-0.0106-0.02890.01101.11490.06510.04081.07770.40871.1484-70.7107-3.9738-76.7935
2900.0414-0.01780.02020.03440.02220.1040.0075-0.0038-0.008-0.15730.00780.3256-0.2865-0.24820.00730.51080.2-0.15090.4199-0.02650.3575-99.9415-4.8045-39.841
2910.0212-0.01440.00610.035-0.03090.0275-0.04530.2544-0.04370.0468-0.01420.1862-0.2058-0.1163-0.00021.20960.2574-0.21410.6243-0.04370.5377-92.7364-5.4626-74.0106
2920.0457-0.0243-0.02130.09030.06020.1599-0.02430.00390.01940.01-0.0212-0.00750.06870.001-0.06250.46620.158-0.12210.32210.00340.2334-20.7476-125.30424.2317
2930-0.0010.00150.0012-00.00360.027-0.0085-0.01030.054-0.0017-0.00680.0205-0.01620.01970.27160.1305-0.14570.3909-0.010.1983-17.0519-111.9938-2.4063
2940.0481-0.00380.01530.01650.01080.01390.034-0.0322-0.0352-0.020.08030.02610.0384-0.04070.09750.25580.0613-0.21750.26820.01490.3203-18.316-108.3615-7.7947
2950.00180.0060.00280.00990.00480.0046-0.06660.0430.0610.09150.0783-0.06840.03740.1088-0.03070.2291-0.0041-0.18880.2574-0.01890.2465-16.7304-111.6093-5.9647
2960.03370.02260.02060.02470.00430.01820.0297-0.00860.007-0.04160.02190.01340.06580.07820.06820.28260.1443-0.17140.3731-0.06270.2987-7.7513-113.64430.259
2970.00940.00660.00420.00390.0034-0.00070.0067-0.01860.01930.0151-0.0371-0.03530.07830.1341-00.40890.1345-0.09120.3934-0.06960.2929-11.4739-131.1004-10.5829
2980.00610.0006-0.00570.0032-0.0030.00410.05170.02980.04340.04150.04460.01620.0324-0.035300.4346-0.0001-0.09740.29140.10070.3553-31.2722-119.9951-0.6853
2990.06720.0388-0.01120.035-0.00350.0047-0.03280.0150.03150.00580.0043-0.11160.04150.0245-0.00910.33760.0914-0.12460.2773-0.00050.2467-21.2842-130.7656-17.952
3000.00540.00160.0040.0034-0.00310.0066-0.10460.03230.11690.0211-0.1092-0.01170.1181-0.0354-0.00010.46630.0234-0.04820.3417-0.01330.3114-27-127.1636-8.313
3010.001-0.00170.00070.02350.02250.0188-0.0329-0.02720.00250.0150.11580.03610.0541-0.04450.02830.30550.1002-0.14910.3620.02270.2075-22.1437-126.599-11.5926
3020.00290.0026-0.00310.0008-0.00090.00390.05790.00240.0015-0.0135-0.0078-0.04320.00580.1261-00.20390.0772-0.07270.3436-0.01480.2904-8.3831-119.1249-14.5129
3030.00950.0037-0.00660.01060.00530.00780.0085-0.0966-0.0447-0.08020.05170.05480.035-0.05680.08130.4119-0.0032-0.09390.16940.06070.0676-42.4085-132.7476-39.0394
3040.009-0.01130.01180.08160.01830.02070.0420.1315-0.0172-0.1032-0.0503-0.0710.02350.0150.00870.25750.0237-0.04480.23560.04260.1194-36.0267-127.2263-41.5062
3050.20080.0461-0.08530.0655-0.00630.1175-0.11740.0914-0.0673-0.1017-0.06790.0343-0.116-0.0568-0.35190.49330.0773-0.1690.1959-0.05630.1351-39.1198-142.4864-58.7252
3060.0150.0043-0.00050.00470.00240.00530.10070.0155-0.0421-0.01540.00710.05140.0879-0.0073-00.7638-0.0316-0.07520.6046-0.12510.4103-45.5348-145.6549-68.5203
3070.0043-0.0015-0.00010.0055-0.00420.003-0.013-0.0115-0.0132-0.00430.03980.0074-0.0024-0.0246-00.6724-0.1524-0.00790.45460.01840.6376-46.7965-154.8732-67.4389
3080.0098-0.00670.00140.0078-0.00770.0116-0.05570.1485-0.0288-0.0401-0.0425-0.02650.11090.007200.6975-0.07290.02490.3655-0.02950.404-39.8674-146.3148-68.6835
3090.01130.0030.00880.00030.00310.00480.0068-0.01420.0279-0.0862-0.00290.03430.0859-0.036801.009-0.0423-0.19190.8645-0.32340.5998-50.125-149.9079-76.4451
3100.0726-0.0174-0.01860.0127-0.00660.0184-0.0245-0.03790.0731-0.2290.1479-0.18440.29320.07250.00240.42550.0835-0.00770.3733-0.05020.2638-18.6676-143.0495-39.6431
3110.0197-0.0012-0.0216-0.00210.00970.05460.0087-0.0357-0.06570.02930.0247-0.07930.23880.04960.01350.34440.104-0.00840.2047-0.0290.1337-23.6502-147.3324-39.3047
3120.0126-0.0030.00280.01720.00280.01250.06180.16440.0186-0.0480.0503-0.1843-0.0239-0.0142-00.89670.02810.08380.36990.01120.4061-30.7731-145.0514-71.6153
3130.0015-0.0002-0.0016-0.00090.00130.00180.06950.0502-0.0018-0.0661-0.0152-0.1781-0.0197-0.0266-00.84750.03310.21020.81540.13120.7425-23.8884-145.3606-77.5863
3140.0038-0.001-0.0023-0.00050.00030.00020.01040.0107-0.00940.0609-0.0513-0.02840.0349-0.0711-00.2731-0.0158-0.01180.21790.00910.3712-75.768-140.9714-91.1828
3150.0175-0.00590.00230.0343-0.02540.03110.0019-0.0751-0.08240.0471-0.0506-0.1010.02140.039-0.1371-0.1487-0.1528-0.09020.0084-0.02560.1981-62.2438-130.8327-91.3876
3160.0409-0.0322-0.00180.03220.00760.0201-0.16120.0687-0.1575-0.099-0.0586-0.13060.20690.014700.3879-0.01260.02060.3176-0.05170.4198-62.7692-138.4773-102.3394
3170.02630.0167-0.00070.0106-0.00420.01450.00460.0534-0.0585-0.06710.0536-0.04930.025-0.02170.03160.2757-0.1071-0.04060.3199-0.11530.35-78.754-134.0332-100.0018
3180.00150.00470.00360.0130.0030.00520.08860.0340.0166-0.0830.0928-0.08430.0046-0.047-00.3461-0.05230.03380.3023-0.09680.2729-76.4474-133.4455-111.0872
3190.00150.00080.00020.00580.00350.013-0.07020.1119-0.0146-0.0030.0212-0.0461-0.073-0.170500.288-0.04390.03110.2404-0.04720.3561-74.8943-135.1472-105.9561
3200.0110.003-0.02670.001-0.01020.073-0.0670.0172-0.0232-0.0604-0.0683-0.00660.0925-0.0429-00.23980.02260.12780.1579-0.06340.4736-59.3108-138.2723-107.3403
3210.00030.00450.00270.0152-0.01010.0079-0.04090.11330.0145-0.11140.04570.0233-0.01090.01750.03540.4625-0.2208-0.14970.5856-0.08820.1146-89.2118-115.6969-131.0712
3220.0449-0.01090.02380.1623-0.10030.0747-0.03230.05880.002-0.1501-0.1265-0.0010.0329-0.0104-0.09050.4998-0.1511-0.01090.5993-0.06840.2287-80.0163-116.4964-129.6293
3230.00020.00710.00620.010.01520.01750.03630.1942-0.0507-0.0917-0.09550.0171-0.08360.0297-0.02620.5943-0.1589-0.04440.7045-0.02960.2529-85.3809-119.2376-133.4749
3240.09040.08290.00940.0785-0.01820.06050.04760.0173-0.02360.0171-0.0904-0.00490.0372-0.0375-0.05330.8453-0.0564-0.23720.8873-0.09190.2357-89.5982-112.6382-164.7455
3250.00690.0006-0.00480.00010.00050.00310.004-0.0639-0.0368-0.06240.00570.06660.01980.031301.0631-0.0972-0.22811.3088-0.31720.6352-94.9399-111.4256-162.273
3260.0024-0.003-0.00360.00260.00420.00530.03750.04370.0371-0.0031-0.10950.0162-0.0158-0.0356-00.9336-0.0608-0.06341.0949-0.02750.4999-92.3938-113.1772-159.476
3270.00650.0005-0.0024-0.00080.00040.00460.0125-0.07810.03020.02020.02910.0113-0.00440.0154-01.2789-0.0685-0.46551.5828-0.2831.0334-100.6076-116.5922-171.1822
3280.0061-0.00680.00170.0053-0.00130.0005-0.0012-0.05440.0164-0.021-0.019-0.00620.01480.011101.28660.1184-0.41891.3965-0.13550.9762-98.1649-105.7073-170.5146
3290.0433-0.04530.00560.0583-0.02250.0166-0.01360.173-0.0942-0.15890.04660.01540.1045-0.0247-0.01150.6962-0.1809-0.00010.68-0.26510.2636-78.2043-138.1318-138.2879
330-0.0005-0.0041-0.0030.01120.01050.0085-0.09250.0335-0.1336-0.0856-0.06930.03920.0068-0.0371-0.00010.6035-0.0679-0.07010.6208-0.22690.5291-86.4744-136.5745-132.2091
3310.0038-0.00570.00090.0118-0.0023-0.0003-0.04650.1391-0.1016-0.2369-0.07570.09870.0112-0.1179-0.12990.6183-0.2373-0.05480.802-0.30810.3274-84.2147-138.2536-141.205
3320.0351-0.01720.00510.0472-0.01970.00820.08320.05950.1107-0.0089-0.1572-0.10430.0273-0.0892-0.00011.45160.0155-0.13661.141-0.00620.4007-82.7807-120.8008-169.2953
3330.00260.00780.00920.01020.01540.0270.06430.12980.056-0.029-0.1339-0.05490.0712-0.044701.4321-0.1044-0.02461.36620.03560.4637-82.1244-116.7424-167.5047
334-0.0011-0.00110.00080.00470.00520.0054-0.03430.00820.02030.0115-0.05230.0037-0.0020.0105-01.38380.022-0.04171.1195-0.13850.7698-78.29-125.2617-172.8653
3350.0269-0.008-0.00260.02520.01610.01110.02840.04050.0507-0.0073-0.0230.0478-0.05850.0667-0.00770.24420.03430.13690.2683-0.02990.3853-44.6547-9.8855-91.6278
3360.06190.0481-0.00710.09490.06770.09790.0801-0.11450.03450.16130.04730.0426-0.1331-0.01150.1930.15450.13350.25520.16930.02470.1227-58.1068-20.0895-92.0178
3370.054-0.0252-0.00250.0578-0.00570.0180.2057-0.02620.1018-0.0163-0.04690.1104-0.2108-0.04910.15180.30830.08190.18820.27750.07330.1709-51.3976-14.3616-102.3847
3380.0411-0.04190.01050.0446-0.01080.02740.208-0.09320.0136-0.03580.05210.0901-0.04530.06720.01230.23410.06310.08790.26370.07370.2191-43.2648-18.0043-111.0202
3390.0079-0.00320.00930.0002-0.00330.01120.07350.01550.03060.0770.04080.057-0.04830.07600.35290.0330.04660.2383-0.01310.2817-44.9411-16.1567-106.2724
3400.00240.0011-0.00090.0061-0.00710.0064-0.0034-0.00110.0115-0.0577-0.0113-0.0034-0.0288-0.0281-0.02580.28090.17620.1050.22950.10670.2284-60.5115-13.1613-108.3455
3410.06960.0175-0.02790.2685-0.17010.10430.01840.1619-0.0708-0.3285-0.0342-0.17540.150.0011-0.03120.147-0.0540.28170.14580.1688-0.1317-33.4521-36.5979-132.8523
3420.0024-0.012-0.0140.07560.00770.0848-0.08180.0205-0.0675-0.1688-0.0843-0.0474-0.06620.052-0.06191.4801-0.10980.60950.8493-0.04410.747-22.6251-38.4349-166.0961
3430.0021-0.00450.00050.0061-0.00560.00960.07660.02360.0002-0.0339-0.0218-0.07560.07180.001400.8656-0.04320.21650.63370.07740.5405-24.0081-39.4848-158.537
3440.0294-0.0108-0.03150.00420.01130.0285-0.01470.0193-0.03340.007-0.0096-0.0202-0.00490.0592-0.05181.32620.03650.76190.9292-0.050.9076-17.2803-40.7939-168.175
345-0.00040.0003-0.00120.00240.0013-0.0002-0.02550.03050.011-0.12570.0121-0.0173-0.0597-0.0365-0.00740.38430.08880.07910.55330.16710.1891-39.5863-13.7266-145.8295
3460.06430.01640.00670.01160.00250.0374-0.00150.02760.0533-0.12110.0012-0.0308-0.0091-0.0735-0.01880.35330.17760.04420.20430.15690.1368-37.5285-15.2513-133.4603
3470.01450.02560.00090.04370.00210.08370.02290.0210.056-0.091-0.0227-0.06640.0372-0.0911-0.0650.42640.06430.0780.36340.1150.2618-34.4718-14.3556-141.4724
348-0.0008-0-0.0017-0-0.00040.006-0.01970.0424-0.0029-0.0105-0.0076-0.0001-0.0057-0.005501.4734-0.02080.04161.0746-0.08191.0294-30.2461-37.8165-174.4627
349-0.00020.0031-0.00590.0025-0.00680.0169-0.0710.0484-0.0511-0.0642-0.03980.05290.0196-0.0428-01.3977-0.14920.05380.85640.09990.5094-34.1282-30.0839-165.8449
3500.0021-0.00010.00220.0013-0.00010.0019-0.02340.0082-0.0071-0.0196-0.03570.0542-0.0131-0.0096-01.3065-0.0481-0.16531.2564-0.06771.2205-42.0794-39.4615-165.3284
3510.0183-0.0102-0.00330.00580.00210.00070.04520.01930.0469-0.0127-0.0079-0.0244-0.0094-0.00970.00031.1038-0.08030.15330.5390.22390.4103-27.2132-26.412-160.8054
3520.00110.0028-0.00010.0052-0.00350.00490.00820.0277-0.00610.0423-0.0165-0.0105-0.0283-0.0117-01.5183-0.2137-0.27191.1706-0.17680.8809-38.4306-44.7766-174.0662
353-0.00030.0019-0.00130.0045-0.00350.0024-0.0476-0.0177-0.0073-0.0213-0.037-0.01340.0227-0.0151-01.4359-0.0816-0.13041.05260.16571.0436-38.5167-28.6196-172.5244
精密化 TLSグループ
IDRefine-IDRefine TLS-IDSelection detailsAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1chain 'W' and (resid 16 through 29 )W16 - 29
2X-RAY DIFFRACTION2chain 'W' and (resid 30 through 90 )W30 - 90
3X-RAY DIFFRACTION3chain 'W' and (resid 91 through 124A)W91 - 124
4X-RAY DIFFRACTION4chain 'W' and (resid 125 through 140 )W125 - 140
5X-RAY DIFFRACTION5chain 'W' and (resid 141 through 155 )W141 - 155
6X-RAY DIFFRACTION6chain 'W' and (resid 156 through 183 )W156 - 183
7X-RAY DIFFRACTION7chain 'W' and (resid 184 through 197 )W184 - 197
8X-RAY DIFFRACTION8chain 'W' and (resid 198 through 225 )W198 - 225
9X-RAY DIFFRACTION9chain 'W' and (resid 226 through 243 )W226 - 243
10X-RAY DIFFRACTION10chain 'L' and (resid 1 through 90 )L1 - 90
11X-RAY DIFFRACTION11chain 'L' and (resid 91 through 113 )L91 - 113
12X-RAY DIFFRACTION12chain 'L' and (resid 114 through 150 )L114 - 150
13X-RAY DIFFRACTION13chain 'L' and (resid 151 through 163 )L151 - 163
14X-RAY DIFFRACTION14chain 'L' and (resid 164 through 187 )L164 - 187
15X-RAY DIFFRACTION15chain 'L' and (resid 188 through 213 )L188 - 213
16X-RAY DIFFRACTION16chain 'M' and (resid 1 through 121 )M1 - 121
17X-RAY DIFFRACTION17chain 'M' and (resid 122 through 156 )M122 - 156
18X-RAY DIFFRACTION18chain 'M' and (resid 157 through 217 )M157 - 217
19X-RAY DIFFRACTION19chain 'C' and (resid 16 through 29 )C16 - 29
20X-RAY DIFFRACTION20chain 'C' and (resid 30 through 48 )C30 - 48
21X-RAY DIFFRACTION21chain 'C' and (resid 49 through 68 )C49 - 68
22X-RAY DIFFRACTION22chain 'C' and (resid 69 through 103 )C69 - 103
23X-RAY DIFFRACTION23chain 'C' and (resid 104 through 124A)C104 - 124
24X-RAY DIFFRACTION24chain 'C' and (resid 125 through 140 )C125 - 140
25X-RAY DIFFRACTION25chain 'C' and (resid 141 through 155 )C141 - 155
26X-RAY DIFFRACTION26chain 'C' and (resid 156 through 183 )C156 - 183
27X-RAY DIFFRACTION27chain 'C' and (resid 184 through 197 )C184 - 197
28X-RAY DIFFRACTION28chain 'C' and (resid 198 through 225 )C198 - 225
29X-RAY DIFFRACTION29chain 'C' and (resid 226 through 243 )C226 - 243
30X-RAY DIFFRACTION30chain 'A' and (resid 1 through 121 )A1 - 121
31X-RAY DIFFRACTION31chain 'A' and (resid 122 through 150 )A122 - 150
32X-RAY DIFFRACTION32chain 'A' and (resid 151 through 174 )A151 - 174
33X-RAY DIFFRACTION33chain 'A' and (resid 175 through 213 )A175 - 213
34X-RAY DIFFRACTION34chain 'B' and (resid 1 through 121 )B1 - 121
35X-RAY DIFFRACTION35chain 'B' and (resid 122 through 145 )B122 - 145
36X-RAY DIFFRACTION36chain 'B' and (resid 146 through 179 )B146 - 179
37X-RAY DIFFRACTION37chain 'B' and (resid 180 through 217 )B180 - 217
38X-RAY DIFFRACTION38chain 'F' and (resid 16 through 29 )F16 - 29
39X-RAY DIFFRACTION39chain 'F' and (resid 30 through 90 )F30 - 90
40X-RAY DIFFRACTION40chain 'F' and (resid 91 through 124A)F91 - 124
41X-RAY DIFFRACTION41chain 'F' and (resid 125 through 140 )F125 - 140
42X-RAY DIFFRACTION42chain 'F' and (resid 141 through 183 )F141 - 183
43X-RAY DIFFRACTION43chain 'F' and (resid 184 through 197 )F184 - 197
44X-RAY DIFFRACTION44chain 'F' and (resid 198 through 225 )F198 - 225
45X-RAY DIFFRACTION45chain 'F' and (resid 226 through 243 )F226 - 243
46X-RAY DIFFRACTION46chain 'D' and (resid 1 through 38 )D1 - 38
47X-RAY DIFFRACTION47chain 'D' and (resid 39 through 61 )D39 - 61
48X-RAY DIFFRACTION48chain 'D' and (resid 62 through 90 )D62 - 90
49X-RAY DIFFRACTION49chain 'D' and (resid 91 through 106 )D91 - 106
50X-RAY DIFFRACTION50chain 'D' and (resid 107 through 136 )D107 - 136
51X-RAY DIFFRACTION51chain 'D' and (resid 137 through 150 )D137 - 150
52X-RAY DIFFRACTION52chain 'D' and (resid 151 through 174 )D151 - 174
53X-RAY DIFFRACTION53chain 'D' and (resid 175 through 197 )D175 - 197
54X-RAY DIFFRACTION54chain 'D' and (resid 198 through 213 )D198 - 213
55X-RAY DIFFRACTION55chain 'E' and (resid 1 through 17 )E1 - 17
56X-RAY DIFFRACTION56chain 'E' and (resid 18 through 51 )E18 - 51
57X-RAY DIFFRACTION57chain 'E' and (resid 52 through 67 )E52 - 67
58X-RAY DIFFRACTION58chain 'E' and (resid 68 through 121 )E68 - 121
59X-RAY DIFFRACTION59chain 'E' and (resid 122 through 159 )E122 - 159
60X-RAY DIFFRACTION60chain 'E' and (resid 160 through 190 )E160 - 190
61X-RAY DIFFRACTION61chain 'E' and (resid 191 through 202 )E191 - 202
62X-RAY DIFFRACTION62chain 'E' and (resid 203 through 217 )E203 - 217
63X-RAY DIFFRACTION63chain 'I' and (resid 16 through 29 )I16 - 29
64X-RAY DIFFRACTION64chain 'I' and (resid 30 through 68 )I30 - 68
65X-RAY DIFFRACTION65chain 'I' and (resid 69 through 124A)I69 - 124
66X-RAY DIFFRACTION66chain 'I' and (resid 125 through 140 )I125 - 140
67X-RAY DIFFRACTION67chain 'I' and (resid 141 through 155 )I141 - 155
68X-RAY DIFFRACTION68chain 'I' and (resid 156 through 183 )I156 - 183
69X-RAY DIFFRACTION69chain 'I' and (resid 184 through 197 )I184 - 197
70X-RAY DIFFRACTION70chain 'I' and (resid 198 through 225 )I198 - 225
71X-RAY DIFFRACTION71chain 'I' and (resid 226 through 243 )I226 - 243
72X-RAY DIFFRACTION72chain 'G' and (resid 1 through 90 )G1 - 90
73X-RAY DIFFRACTION73chain 'G' and (resid 91 through 128 )G91 - 128
74X-RAY DIFFRACTION74chain 'G' and (resid 129 through 150 )G129 - 150
75X-RAY DIFFRACTION75chain 'G' and (resid 151 through 213 )G151 - 213
76X-RAY DIFFRACTION76chain 'H' and (resid 1 through 17 )H1 - 17
77X-RAY DIFFRACTION77chain 'H' and (resid 18 through 61 )H18 - 61
78X-RAY DIFFRACTION78chain 'H' and (resid 62 through 76 )H62 - 76
79X-RAY DIFFRACTION79chain 'H' and (resid 77 through 108 )H77 - 108
80X-RAY DIFFRACTION80chain 'H' and (resid 109 through 145 )H109 - 145
81X-RAY DIFFRACTION81chain 'H' and (resid 146 through 161 )H146 - 161
82X-RAY DIFFRACTION82chain 'H' and (resid 162 through 179 )H162 - 179
83X-RAY DIFFRACTION83chain 'H' and (resid 180 through 202 )H180 - 202
84X-RAY DIFFRACTION84chain 'H' and (resid 203 through 217 )H203 - 217
85X-RAY DIFFRACTION85chain 'N' and (resid 16 through 29 )N16 - 29
86X-RAY DIFFRACTION86chain 'N' and (resid 30 through 90 )N30 - 90
87X-RAY DIFFRACTION87chain 'N' and (resid 91 through 124A)N91 - 124
88X-RAY DIFFRACTION88chain 'N' and (resid 125 through 140 )N125 - 140
89X-RAY DIFFRACTION89chain 'N' and (resid 141 through 155 )N141 - 155
90X-RAY DIFFRACTION90chain 'N' and (resid 156 through 183 )N156 - 183
91X-RAY DIFFRACTION91chain 'N' and (resid 184 through 197 )N184 - 197
92X-RAY DIFFRACTION92chain 'N' and (resid 198 through 225 )N198 - 225
93X-RAY DIFFRACTION93chain 'N' and (resid 226 through 243 )N226 - 243
94X-RAY DIFFRACTION94chain 'J' and (resid 1 through 38 )J1 - 38
95X-RAY DIFFRACTION95chain 'J' and (resid 39 through 75 )J39 - 75
96X-RAY DIFFRACTION96chain 'J' and (resid 76 through 102 )J76 - 102
97X-RAY DIFFRACTION97chain 'J' and (resid 103 through 128 )J103 - 128
98X-RAY DIFFRACTION98chain 'J' and (resid 129 through 150 )J129 - 150
99X-RAY DIFFRACTION99chain 'J' and (resid 151 through 174 )J151 - 174
100X-RAY DIFFRACTION100chain 'J' and (resid 175 through 197 )J175 - 197
101X-RAY DIFFRACTION101chain 'J' and (resid 198 through 213 )J198 - 213
102X-RAY DIFFRACTION102chain 'K' and (resid 1 through 121 )K1 - 121
103X-RAY DIFFRACTION103chain 'K' and (resid 122 through 159 )K122 - 159
104X-RAY DIFFRACTION104chain 'K' and (resid 160 through 190 )K160 - 190
105X-RAY DIFFRACTION105chain 'K' and (resid 191 through 217 )K191 - 217
106X-RAY DIFFRACTION106chain 'Q' and (resid 16 through 29 )Q16 - 29
107X-RAY DIFFRACTION107chain 'Q' and (resid 30 through 80 )Q30 - 80
108X-RAY DIFFRACTION108chain 'Q' and (resid 81 through 124A)Q81 - 124
109X-RAY DIFFRACTION109chain 'Q' and (resid 125 through 140 )Q125 - 140
110X-RAY DIFFRACTION110chain 'Q' and (resid 141 through 155 )Q141 - 155
111X-RAY DIFFRACTION111chain 'Q' and (resid 156 through 183 )Q156 - 183
112X-RAY DIFFRACTION112chain 'Q' and (resid 184 through 197 )Q184 - 197
113X-RAY DIFFRACTION113chain 'Q' and (resid 198 through 225 )Q198 - 225
114X-RAY DIFFRACTION114chain 'Q' and (resid 226 through 243 )Q226 - 243
115X-RAY DIFFRACTION115chain 'O' and (resid 1 through 38 )O1 - 38
116X-RAY DIFFRACTION116chain 'O' and (resid 39 through 75 )O39 - 75
117X-RAY DIFFRACTION117chain 'O' and (resid 76 through 102 )O76 - 102
118X-RAY DIFFRACTION118chain 'O' and (resid 103 through 113 )O103 - 113
119X-RAY DIFFRACTION119chain 'O' and (resid 114 through 128 )O114 - 128
120X-RAY DIFFRACTION120chain 'O' and (resid 129 through 150 )O129 - 150
121X-RAY DIFFRACTION121chain 'O' and (resid 151 through 174 )O151 - 174
122X-RAY DIFFRACTION122chain 'O' and (resid 175 through 197 )O175 - 197
123X-RAY DIFFRACTION123chain 'O' and (resid 198 through 213 )O198 - 213
124X-RAY DIFFRACTION124chain 'P' and (resid 1 through 108 )P1 - 108
125X-RAY DIFFRACTION125chain 'P' and (resid 109 through 136 )P109 - 136
126X-RAY DIFFRACTION126chain 'P' and (resid 137 through 190 )P137 - 190
127X-RAY DIFFRACTION127chain 'P' and (resid 191 through 217 )P191 - 217
128X-RAY DIFFRACTION128chain 'T' and (resid 16 through 29 )T16 - 29
129X-RAY DIFFRACTION129chain 'T' and (resid 30 through 68 )T30 - 68
130X-RAY DIFFRACTION130chain 'T' and (resid 69 through 103 )T69 - 103
131X-RAY DIFFRACTION131chain 'T' and (resid 104 through 124A)T104 - 124
132X-RAY DIFFRACTION132chain 'T' and (resid 125 through 140 )T125 - 140
133X-RAY DIFFRACTION133chain 'T' and (resid 141 through 155 )T141 - 155
134X-RAY DIFFRACTION134chain 'T' and (resid 156 through 183 )T156 - 183
135X-RAY DIFFRACTION135chain 'T' and (resid 184 through 197 )T184 - 197
136X-RAY DIFFRACTION136chain 'T' and (resid 198 through 225 )T198 - 225
137X-RAY DIFFRACTION137chain 'T' and (resid 226 through 243 )T226 - 243
138X-RAY DIFFRACTION138chain 'R' and (resid 1 through 128 )R1 - 128
139X-RAY DIFFRACTION139chain 'R' and (resid 129 through 213 )R129 - 213
140X-RAY DIFFRACTION140chain 'S' and (resid 1 through 17 )S1 - 17
141X-RAY DIFFRACTION141chain 'S' and (resid 18 through 39 )S18 - 39
142X-RAY DIFFRACTION142chain 'S' and (resid 40 through 60 )S40 - 60
143X-RAY DIFFRACTION143chain 'S' and (resid 61 through 76 )S61 - 76
144X-RAY DIFFRACTION144chain 'S' and (resid 77 through 91 )S77 - 91
145X-RAY DIFFRACTION145chain 'S' and (resid 92 through 108 )S92 - 108
146X-RAY DIFFRACTION146chain 'S' and (resid 109 through 136 )S109 - 136
147X-RAY DIFFRACTION147chain 'S' and (resid 137 through 156 )S137 - 156
148X-RAY DIFFRACTION148chain 'S' and (resid 157 through 167 )S157 - 167
149X-RAY DIFFRACTION149chain 'S' and (resid 168 through 179 )S168 - 179
150X-RAY DIFFRACTION150chain 'S' and (resid 180 through 190 )S180 - 190
151X-RAY DIFFRACTION151chain 'S' and (resid 191 through 202 )S191 - 202
152X-RAY DIFFRACTION152chain 'S' and (resid 203 through 217 )S203 - 217
153X-RAY DIFFRACTION153chain 'X' and (resid 16 through 29 )X16 - 29
154X-RAY DIFFRACTION154chain 'X' and (resid 30 through 90 )X30 - 90
155X-RAY DIFFRACTION155chain 'X' and (resid 91 through 124A)X91 - 124
156X-RAY DIFFRACTION156chain 'X' and (resid 125 through 140 )X125 - 140
157X-RAY DIFFRACTION157chain 'X' and (resid 141 through 155 )X141 - 155
158X-RAY DIFFRACTION158chain 'X' and (resid 156 through 183 )X156 - 183
159X-RAY DIFFRACTION159chain 'X' and (resid 184 through 197 )X184 - 197
160X-RAY DIFFRACTION160chain 'X' and (resid 198 through 225 )X198 - 225
161X-RAY DIFFRACTION161chain 'X' and (resid 226 through 243 )X226 - 243
162X-RAY DIFFRACTION162chain 'U' and (resid 1 through 90 )U1 - 90
163X-RAY DIFFRACTION163chain 'U' and (resid 91 through 128 )U91 - 128
164X-RAY DIFFRACTION164chain 'U' and (resid 129 through 150 )U129 - 150
165X-RAY DIFFRACTION165chain 'U' and (resid 151 through 213 )U151 - 213
166X-RAY DIFFRACTION166chain 'V' and (resid 1 through 17 )V1 - 17
167X-RAY DIFFRACTION167chain 'V' and (resid 18 through 51 )V18 - 51
168X-RAY DIFFRACTION168chain 'V' and (resid 52 through 67 )V52 - 67
169X-RAY DIFFRACTION169chain 'V' and (resid 68 through 99 )V68 - 99
170X-RAY DIFFRACTION170chain 'V' and (resid 100 through 121 )V100 - 121
171X-RAY DIFFRACTION171chain 'V' and (resid 122 through 145 )V122 - 145
172X-RAY DIFFRACTION172chain 'V' and (resid 146 through 159 )V146 - 159
173X-RAY DIFFRACTION173chain 'V' and (resid 160 through 190 )V160 - 190
174X-RAY DIFFRACTION174chain 'V' and (resid 191 through 205 )V191 - 205
175X-RAY DIFFRACTION175chain 'V' and (resid 206 through 217 )V206 - 217
176X-RAY DIFFRACTION176chain 'a' and (resid 16 through 29 )a16 - 29
177X-RAY DIFFRACTION177chain 'a' and (resid 30 through 90 )a30 - 90
178X-RAY DIFFRACTION178chain 'a' and (resid 91 through 124A)a91 - 124
179X-RAY DIFFRACTION179chain 'a' and (resid 125 through 140 )a125 - 140
180X-RAY DIFFRACTION180chain 'a' and (resid 141 through 168 )a141 - 168
181X-RAY DIFFRACTION181chain 'a' and (resid 169 through 197 )a169 - 197
182X-RAY DIFFRACTION182chain 'a' and (resid 198 through 225 )a198 - 225
183X-RAY DIFFRACTION183chain 'a' and (resid 226 through 243 )a226 - 243
184X-RAY DIFFRACTION184chain 'Y' and (resid 1 through 128 )Y1 - 128
185X-RAY DIFFRACTION185chain 'Y' and (resid 129 through 213 )Y129 - 213
186X-RAY DIFFRACTION186chain 'Z' and (resid 1 through 121 )Z1 - 121
187X-RAY DIFFRACTION187chain 'Z' and (resid 122 through 190 )Z122 - 190
188X-RAY DIFFRACTION188chain 'Z' and (resid 191 through 217 )Z191 - 217
189X-RAY DIFFRACTION189chain 'd' and (resid 16 through 29 )d16 - 29
190X-RAY DIFFRACTION190chain 'd' and (resid 30 through 68 )d30 - 68
191X-RAY DIFFRACTION191chain 'd' and (resid 69 through 90 )d69 - 90
192X-RAY DIFFRACTION192chain 'd' and (resid 91 through 124A)d91 - 124
193X-RAY DIFFRACTION193chain 'd' and (resid 125 through 140 )d125 - 140
194X-RAY DIFFRACTION194chain 'd' and (resid 141 through 155 )d141 - 155
195X-RAY DIFFRACTION195chain 'd' and (resid 156 through 183 )d156 - 183
196X-RAY DIFFRACTION196chain 'd' and (resid 184 through 197 )d184 - 197
197X-RAY DIFFRACTION197chain 'd' and (resid 198 through 225 )d198 - 225
198X-RAY DIFFRACTION198chain 'd' and (resid 226 through 243 )d226 - 243
199X-RAY DIFFRACTION199chain 'b' and (resid 1 through 18 )b1 - 18
200X-RAY DIFFRACTION200chain 'b' and (resid 19 through 90 )b19 - 90
201X-RAY DIFFRACTION201chain 'b' and (resid 91 through 128 )b91 - 128
202X-RAY DIFFRACTION202chain 'b' and (resid 129 through 150 )b129 - 150
203X-RAY DIFFRACTION203chain 'b' and (resid 151 through 163 )b151 - 163
204X-RAY DIFFRACTION204chain 'b' and (resid 164 through 174 )b164 - 174
205X-RAY DIFFRACTION205chain 'b' and (resid 175 through 198 )b175 - 198
206X-RAY DIFFRACTION206chain 'b' and (resid 199 through 213 )b199 - 213
207X-RAY DIFFRACTION207chain 'c' and (resid 1 through 17 )c1 - 17
208X-RAY DIFFRACTION208chain 'c' and (resid 18 through 61 )c18 - 61
209X-RAY DIFFRACTION209chain 'c' and (resid 62 through 76 )c62 - 76
210X-RAY DIFFRACTION210chain 'c' and (resid 77 through 136 )c77 - 136
211X-RAY DIFFRACTION211chain 'c' and (resid 137 through 156 )c137 - 156
212X-RAY DIFFRACTION212chain 'c' and (resid 157 through 179 )c157 - 179
213X-RAY DIFFRACTION213chain 'c' and (resid 180 through 190 )c180 - 190
214X-RAY DIFFRACTION214chain 'c' and (resid 191 through 202 )c191 - 202
215X-RAY DIFFRACTION215chain 'c' and (resid 203 through 217 )c203 - 217
216X-RAY DIFFRACTION216chain 'g' and (resid 16 through 29 )g16 - 29
217X-RAY DIFFRACTION217chain 'g' and (resid 30 through 68 )g30 - 68
218X-RAY DIFFRACTION218chain 'g' and (resid 69 through 90 )g69 - 90
219X-RAY DIFFRACTION219chain 'g' and (resid 91 through 124A)g91 - 124
220X-RAY DIFFRACTION220chain 'g' and (resid 125 through 140 )g125 - 140
221X-RAY DIFFRACTION221chain 'g' and (resid 141 through 155 )g141 - 155
222X-RAY DIFFRACTION222chain 'g' and (resid 156 through 168 )g156 - 168
223X-RAY DIFFRACTION223chain 'g' and (resid 169 through 197 )g169 - 197
224X-RAY DIFFRACTION224chain 'g' and (resid 198 through 225 )g198 - 225
225X-RAY DIFFRACTION225chain 'g' and (resid 226 through 243 )g226 - 243
226X-RAY DIFFRACTION226chain 'e' and (resid 1 through 38 )e1 - 38
227X-RAY DIFFRACTION227chain 'e' and (resid 39 through 75 )e39 - 75
228X-RAY DIFFRACTION228chain 'e' and (resid 76 through 102 )e76 - 102
229X-RAY DIFFRACTION229chain 'e' and (resid 103 through 129 )e103 - 129
230X-RAY DIFFRACTION230chain 'e' and (resid 130 through 150 )e130 - 150
231X-RAY DIFFRACTION231chain 'e' and (resid 151 through 174 )e151 - 174
232X-RAY DIFFRACTION232chain 'e' and (resid 175 through 213 )e175 - 213
233X-RAY DIFFRACTION233chain 'f' and (resid 1 through 17 )f1 - 17
234X-RAY DIFFRACTION234chain 'f' and (resid 18 through 51 )f18 - 51
235X-RAY DIFFRACTION235chain 'f' and (resid 52 through 67 )f52 - 67
236X-RAY DIFFRACTION236chain 'f' and (resid 68 through 121 )f68 - 121
237X-RAY DIFFRACTION237chain 'f' and (resid 122 through 145 )f122 - 145
238X-RAY DIFFRACTION238chain 'f' and (resid 146 through 159 )f146 - 159
239X-RAY DIFFRACTION239chain 'f' and (resid 160 through 179 )f160 - 179
240X-RAY DIFFRACTION240chain 'f' and (resid 180 through 190 )f180 - 190
241X-RAY DIFFRACTION241chain 'f' and (resid 191 through 202 )f191 - 202
242X-RAY DIFFRACTION242chain 'f' and (resid 203 through 217 )f203 - 217
243X-RAY DIFFRACTION243chain 'j' and (resid 16 through 29 )j16 - 29
244X-RAY DIFFRACTION244chain 'j' and (resid 30 through 90 )j30 - 90
245X-RAY DIFFRACTION245chain 'j' and (resid 91 through 124A)j91 - 124
246X-RAY DIFFRACTION246chain 'j' and (resid 125 through 140 )j125 - 140
247X-RAY DIFFRACTION247chain 'j' and (resid 141 through 155 )j141 - 155
248X-RAY DIFFRACTION248chain 'j' and (resid 156 through 183 )j156 - 183
249X-RAY DIFFRACTION249chain 'j' and (resid 184 through 197 )j184 - 197
250X-RAY DIFFRACTION250chain 'j' and (resid 198 through 225 )j198 - 225
251X-RAY DIFFRACTION251chain 'j' and (resid 226 through 243 )j226 - 243
252X-RAY DIFFRACTION252chain 'h' and (resid 1 through 75 )h1 - 75
253X-RAY DIFFRACTION253chain 'h' and (resid 76 through 115 )h76 - 115
254X-RAY DIFFRACTION254chain 'h' and (resid 116 through 129 )h116 - 129
255X-RAY DIFFRACTION255chain 'h' and (resid 130 through 150 )h130 - 150
256X-RAY DIFFRACTION256chain 'h' and (resid 151 through 174 )h151 - 174
257X-RAY DIFFRACTION257chain 'h' and (resid 175 through 190 )h175 - 190
258X-RAY DIFFRACTION258chain 'h' and (resid 191 through 213 )h191 - 213
259X-RAY DIFFRACTION259chain 'i' and (resid 1 through 17 )i1 - 17
260X-RAY DIFFRACTION260chain 'i' and (resid 18 through 39 )i18 - 39
261X-RAY DIFFRACTION261chain 'i' and (resid 40 through 60 )i40 - 60
262X-RAY DIFFRACTION262chain 'i' and (resid 61 through 76 )i61 - 76
263X-RAY DIFFRACTION263chain 'i' and (resid 77 through 91 )i77 - 91
264X-RAY DIFFRACTION264chain 'i' and (resid 92 through 108 )i92 - 108
265X-RAY DIFFRACTION265chain 'i' and (resid 109 through 121 )i109 - 121
266X-RAY DIFFRACTION266chain 'i' and (resid 122 through 145 )i122 - 145
267X-RAY DIFFRACTION267chain 'i' and (resid 146 through 161 )i146 - 161
268X-RAY DIFFRACTION268chain 'i' and (resid 162 through 179 )i162 - 179
269X-RAY DIFFRACTION269chain 'i' and (resid 180 through 190 )i180 - 190
270X-RAY DIFFRACTION270chain 'i' and (resid 191 through 202 )i191 - 202
271X-RAY DIFFRACTION271chain 'i' and (resid 203 through 217 )i203 - 217
272X-RAY DIFFRACTION272chain 'm' and (resid 16 through 29 )m16 - 29
273X-RAY DIFFRACTION273chain 'm' and (resid 30 through 68 )m30 - 68
274X-RAY DIFFRACTION274chain 'm' and (resid 69 through 124A)m69 - 124
275X-RAY DIFFRACTION275chain 'm' and (resid 125 through 140 )m125 - 140
276X-RAY DIFFRACTION276chain 'm' and (resid 141 through 155 )m141 - 155
277X-RAY DIFFRACTION277chain 'm' and (resid 156 through 183 )m156 - 183
278X-RAY DIFFRACTION278chain 'm' and (resid 184 through 197 )m184 - 197
279X-RAY DIFFRACTION279chain 'm' and (resid 198 through 225 )m198 - 225
280X-RAY DIFFRACTION280chain 'm' and (resid 226 through 243 )m226 - 243
281X-RAY DIFFRACTION281chain 'k' and (resid 1 through 18 )k1 - 18
282X-RAY DIFFRACTION282chain 'k' and (resid 19 through 75 )k19 - 75
283X-RAY DIFFRACTION283chain 'k' and (resid 76 through 102 )k76 - 102
284X-RAY DIFFRACTION284chain 'k' and (resid 103 through 113 )k103 - 113
285X-RAY DIFFRACTION285chain 'k' and (resid 114 through 128 )k114 - 128
286X-RAY DIFFRACTION286chain 'k' and (resid 129 through 150 )k129 - 150
287X-RAY DIFFRACTION287chain 'k' and (resid 151 through 174 )k151 - 174
288X-RAY DIFFRACTION288chain 'k' and (resid 175 through 197 )k175 - 197
289X-RAY DIFFRACTION289chain 'k' and (resid 198 through 213 )k198 - 213
290X-RAY DIFFRACTION290chain 'l' and (resid 1 through 121 )l1 - 121
291X-RAY DIFFRACTION291chain 'l' and (resid 122 through 217 )l122 - 217
292X-RAY DIFFRACTION292chain 'p' and (resid 16 through 29 )p16 - 29
293X-RAY DIFFRACTION293chain 'p' and (resid 30 through 50 )p30 - 50
294X-RAY DIFFRACTION294chain 'p' and (resid 51 through 68 )p51 - 68
295X-RAY DIFFRACTION295chain 'p' and (resid 69 through 103 )p69 - 103
296X-RAY DIFFRACTION296chain 'p' and (resid 104 through 124A)p104 - 124
297X-RAY DIFFRACTION297chain 'p' and (resid 125 through 140 )p125 - 140
298X-RAY DIFFRACTION298chain 'p' and (resid 141 through 155 )p141 - 155
299X-RAY DIFFRACTION299chain 'p' and (resid 156 through 183 )p156 - 183
300X-RAY DIFFRACTION300chain 'p' and (resid 184 through 197 )p184 - 197
301X-RAY DIFFRACTION301chain 'p' and (resid 198 through 225 )p198 - 225
302X-RAY DIFFRACTION302chain 'p' and (resid 226 through 243 )p226 - 243
303X-RAY DIFFRACTION303chain 'n' and (resid 1 through 38 )n1 - 38
304X-RAY DIFFRACTION304chain 'n' and (resid 39 through 90 )n39 - 90
305X-RAY DIFFRACTION305chain 'n' and (resid 91 through 128 )n91 - 128
306X-RAY DIFFRACTION306chain 'n' and (resid 129 through 150 )n129 - 150
307X-RAY DIFFRACTION307chain 'n' and (resid 151 through 163 )n151 - 163
308X-RAY DIFFRACTION308chain 'n' and (resid 164 through 187 )n164 - 187
309X-RAY DIFFRACTION309chain 'n' and (resid 188 through 213 )n188 - 213
310X-RAY DIFFRACTION310chain 'o' and (resid 1 through 40 )o1 - 40
311X-RAY DIFFRACTION311chain 'o' and (resid 41 through 121 )o41 - 121
312X-RAY DIFFRACTION312chain 'o' and (resid 122 through 190 )o122 - 190
313X-RAY DIFFRACTION313chain 'o' and (resid 191 through 217 )o191 - 217
314X-RAY DIFFRACTION314chain 's' and (resid 16 through 29 )s16 - 29
315X-RAY DIFFRACTION315chain 's' and (resid 30 through 90 )s30 - 90
316X-RAY DIFFRACTION316chain 's' and (resid 91 through 140 )s91 - 140
317X-RAY DIFFRACTION317chain 's' and (resid 141 through 168 )s141 - 168
318X-RAY DIFFRACTION318chain 's' and (resid 169 through 197 )s169 - 197
319X-RAY DIFFRACTION319chain 's' and (resid 198 through 225 )s198 - 225
320X-RAY DIFFRACTION320chain 's' and (resid 226 through 243 )s226 - 243
321X-RAY DIFFRACTION321chain 'q' and (resid 1 through 38 )q1 - 38
322X-RAY DIFFRACTION322chain 'q' and (resid 39 through 75 )q39 - 75
323X-RAY DIFFRACTION323chain 'q' and (resid 76 through 102 )q76 - 102
324X-RAY DIFFRACTION324chain 'q' and (resid 103 through 128 )q103 - 128
325X-RAY DIFFRACTION325chain 'q' and (resid 129 through 150 )q129 - 150
326X-RAY DIFFRACTION326chain 'q' and (resid 151 through 174 )q151 - 174
327X-RAY DIFFRACTION327chain 'q' and (resid 175 through 198 )q175 - 198
328X-RAY DIFFRACTION328chain 'q' and (resid 199 through 213 )q199 - 213
329X-RAY DIFFRACTION329chain 'r' and (resid 1 through 40 )r1 - 40
330X-RAY DIFFRACTION330chain 'r' and (resid 41 through 60 )r41 - 60
331X-RAY DIFFRACTION331chain 'r' and (resid 61 through 121 )r61 - 121
332X-RAY DIFFRACTION332chain 'r' and (resid 122 through 159 )r122 - 159
333X-RAY DIFFRACTION333chain 'r' and (resid 160 through 196 )r160 - 196
334X-RAY DIFFRACTION334chain 'r' and (resid 197 through 217 )r197 - 217
335X-RAY DIFFRACTION335chain 'v' and (resid 16 through 29 )v16 - 29
336X-RAY DIFFRACTION336chain 'v' and (resid 30 through 90 )v30 - 90
337X-RAY DIFFRACTION337chain 'v' and (resid 91 through 169 )v91 - 169
338X-RAY DIFFRACTION338chain 'v' and (resid 170 through 197 )v170 - 197
339X-RAY DIFFRACTION339chain 'v' and (resid 198 through 225 )v198 - 225
340X-RAY DIFFRACTION340chain 'v' and (resid 226 through 243 )v226 - 243
341X-RAY DIFFRACTION341chain 't' and (resid 1 through 115 )t1 - 115
342X-RAY DIFFRACTION342chain 't' and (resid 116 through 150 )t116 - 150
343X-RAY DIFFRACTION343chain 't' and (resid 151 through 172 )t151 - 172
344X-RAY DIFFRACTION344chain 't' and (resid 173 through 213 )t173 - 213
345X-RAY DIFFRACTION345chain 'u' and (resid 1 through 17 )u1 - 17
346X-RAY DIFFRACTION346chain 'u' and (resid 18 through 60 )u18 - 60
347X-RAY DIFFRACTION347chain 'u' and (resid 61 through 121 )u61 - 121
348X-RAY DIFFRACTION348chain 'u' and (resid 122 through 136 )u122 - 136
349X-RAY DIFFRACTION349chain 'u' and (resid 137 through 156 )u137 - 156
350X-RAY DIFFRACTION350chain 'u' and (resid 157 through 167 )u157 - 167
351X-RAY DIFFRACTION351chain 'u' and (resid 168 through 181 )u168 - 181
352X-RAY DIFFRACTION352chain 'u' and (resid 182 through 196 )u182 - 196
353X-RAY DIFFRACTION353chain 'u' and (resid 197 through 217 )u197 - 217

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る