- PDB-5m33: Structural tuning of CD81LEL (space group P21) -
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IDまたはキーワード:
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基本情報
登録情報
データベース: PDB / ID: 5m33
タイトル
Structural tuning of CD81LEL (space group P21)
要素
CD81 antigen
キーワード
CELL ADHESION / human cellular receptor for Hepatitis C virus / signaling protein
機能・相同性
機能・相同性情報
positive regulation of adaptive immune memory response / positive regulation of protein catabolic process in the vacuole / macrophage fusion / CD4-positive, alpha-beta T cell costimulation / positive regulation of B cell receptor signaling pathway / osteoclast fusion / myoblast fusion involved in skeletal muscle regeneration / positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / positive regulation of inflammatory response to antigenic stimulus / regulation of macrophage migration ...positive regulation of adaptive immune memory response / positive regulation of protein catabolic process in the vacuole / macrophage fusion / CD4-positive, alpha-beta T cell costimulation / positive regulation of B cell receptor signaling pathway / osteoclast fusion / myoblast fusion involved in skeletal muscle regeneration / positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / positive regulation of inflammatory response to antigenic stimulus / regulation of macrophage migration / immunological synapse formation / transferrin receptor binding / protein localization to lysosome / tetraspanin-enriched microdomain / positive regulation of protein exit from endoplasmic reticulum / positive regulation of T-helper 2 cell cytokine production / humoral immune response mediated by circulating immunoglobulin / MHC class II protein binding / positive regulation of CD4-positive, alpha-beta T cell proliferation / cholesterol binding / positive regulation of T cell receptor signaling pathway / cellular response to low-density lipoprotein particle stimulus / immunological synapse / positive regulation of receptor clustering / positive regulation of B cell proliferation / Regulation of Complement cascade / basal plasma membrane / protein localization to plasma membrane / regulation of protein stability / receptor internalization / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / MHC class II protein complex binding / integrin binding / virus receptor activity / basolateral plasma membrane / vesicle / positive regulation of MAPK cascade / focal adhesion / positive regulation of transcription by RNA polymerase II / extracellular exosome / membrane / plasma membrane / cytosol 類似検索 - 分子機能
Cd81 Antigen, Extracellular Domain; Chain: A / Tetraspanin / Tetraspanin, conserved site / Transmembrane 4 family signature. / Tetraspanin, animals / Tetraspanin, EC2 domain superfamily / Tetraspanin/Peripherin / Tetraspanin family / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性
温度: 294.15 K / 手法: 蒸気拡散法, シッティングドロップ法 / pH: 5 詳細: Protein: 10 mg/ml Buffer: 0.1 M MIB pH 5.0, 25% w/v PEG 1500 grown in presence of synthetic claudin-I long-extracellular-loop (CLDN1-EL1) - but not visible in electron density. cryo- ...詳細: Protein: 10 mg/ml Buffer: 0.1 M MIB pH 5.0, 25% w/v PEG 1500 grown in presence of synthetic claudin-I long-extracellular-loop (CLDN1-EL1) - but not visible in electron density. cryo-protectant: 25% glycerol + peptide