登録情報 データベース : PDB / ID : 4ydv 構造の表示 ダウンロードとリンクタイトル STRUCTURE OF THE ANTIBODY 7B2 THAT CAPTURES HIV-1 VIRIONS 要素HIV ANTIBODY 7B2 HEAVY CHAIN,IgG H chain HIV ANTIBODY 7B2 LIGHT CHAIN,Ig kappa chain C region HIV GP41 PEPTIDE GP41(596-606) 詳細キーワード IMMUNE SYSTEM / IGG / HIV / ANTIBODY / HIV GP41 ENVELOPE PROTEIN機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
IgD immunoglobulin complex / IgM immunoglobulin complex / IgA immunoglobulin complex / IgE immunoglobulin complex / Synthesis and processing of ENV and VPU / evasion of host immune response / CD22 mediated BCR regulation / Alpha-defensins / IgG immunoglobulin complex / Fc epsilon receptor (FCERI) signaling ... IgD immunoglobulin complex / IgM immunoglobulin complex / IgA immunoglobulin complex / IgE immunoglobulin complex / Synthesis and processing of ENV and VPU / evasion of host immune response / CD22 mediated BCR regulation / Alpha-defensins / IgG immunoglobulin complex / Fc epsilon receptor (FCERI) signaling / Classical antibody-mediated complement activation / Initial triggering of complement / Dectin-2 family / FCGR activation / immunoglobulin mediated immune response / Binding and entry of HIV virion / Role of phospholipids in phagocytosis / Role of LAT2/NTAL/LAB on calcium mobilization / Scavenging of heme from plasma / immunoglobulin complex, circulating / immunoglobulin receptor binding / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / FCERI mediated Ca+2 mobilization / FCGR3A-mediated IL10 synthesis / complement activation, classical pathway / host cell endosome membrane / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / actin filament organization / Regulation of Complement cascade / antigen binding / Cell surface interactions at the vascular wall / FCERI mediated MAPK activation / FCGR3A-mediated phagocytosis / B cell receptor signaling pathway / Assembly Of The HIV Virion / Budding and maturation of HIV virion / Regulation of actin dynamics for phagocytic cup formation / FCERI mediated NF-kB activation / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / antibacterial humoral response / clathrin-dependent endocytosis of virus by host cell / adaptive immune response / Potential therapeutics for SARS / blood microparticle / viral protein processing / symbiont entry into host cell / immune response / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / apoptotic process / host cell plasma membrane / structural molecule activity / virion membrane / extracellular space / extracellular exosome / extracellular region / membrane / plasma membrane 類似検索 - 分子機能 Envelope glycoprotein Gp160 / : / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120 / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain ... Envelope glycoprotein Gp160 / : / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120 / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / : / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulin subtype / Immunoglobulin / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性 Immunoglobulin kappa constant / Envelope glycoprotein gp160 / IgG H chain 類似検索 - 構成要素生物種 Homo sapiens (ヒト) Human immunodeficiency virus 1 (ヒト免疫不全ウイルス)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.7 Å 詳細データ登録者 Nicely, N.I. / Pemble IV, C.W. 引用ジャーナル : Plos Pathog. / 年 : 2015タイトル : Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.著者: Santra, S. / Tomaras, G.D. / Warrier, R. / Nicely, N.I. / Liao, H.X. / Pollara, J. / Liu, P. / Alam, S.M. / Zhang, R. / Cocklin, S.L. / Shen, X. / Duffy, R. / Xia, S.M. / Schutte, R.J. / ... 著者 : Santra, S. / Tomaras, G.D. / Warrier, R. / Nicely, N.I. / Liao, H.X. / Pollara, J. / Liu, P. / Alam, S.M. / Zhang, R. / Cocklin, S.L. / Shen, X. / Duffy, R. / Xia, S.M. / Schutte, R.J. / Pemble Iv, C.W. / Dennison, S.M. / Li, H. / Chao, A. / Vidnovic, K. / Evans, A. / Klein, K. / Kumar, A. / Robinson, J. / Landucci, G. / Forthal, D.N. / Montefiori, D.C. / Kaewkungwal, J. / Nitayaphan, S. / Pitisuttithum, P. / Rerks-Ngarm, S. / Robb, M.L. / Michael, N.L. / Kim, J.H. / Soderberg, K.A. / Giorgi, E.E. / Blair, L. / Korber, B.T. / Moog, C. / Shattock, R.J. / Letvin, N.L. / Schmitz, J.E. / Moody, M.A. / Gao, F. / Ferrari, G. / Shaw, G.M. / Haynes, B.F. 履歴 登録 2015年2月23日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2015年8月12日 Provider : repository / タイプ : Initial release改定 1.1 2021年3月24日 Group : Derived calculations / Source and taxonomy / カテゴリ : entity_src_gen / pdbx_struct_oper_listItem : _entity_src_gen.pdbx_host_org_cell_line / _entity_src_gen.pdbx_host_org_strain / _pdbx_struct_oper_list.symmetry_operation
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