登録情報 データベース : PDB / ID : 3oqs 構造の表示 ダウンロードとリンクタイトル Crystal structure of importin-alpha bound to a CLIC4 NLS peptide 要素Importin subunit alpha-2 peptide of Chloride intracellular channel protein 4 詳細キーワード PROTEIN TRANSPORT / importin alpha / karyopherin alpha / nuclear localisation signal (NLS) recognition / chloride intracellular channel 4 / CLIC4 NLS / Armadillo repeat / Nuclear import機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
establishment or maintenance of apical/basal cell polarity / retina vasculature morphogenesis in camera-type eye / Sensing of DNA Double Strand Breaks / endothelial cell morphogenesis / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / fertilization / chloride transport ... establishment or maintenance of apical/basal cell polarity / retina vasculature morphogenesis in camera-type eye / Sensing of DNA Double Strand Breaks / endothelial cell morphogenesis / entry of viral genome into host nucleus through nuclear pore complex via importin / positive regulation of viral life cycle / NLS-dependent protein nuclear import complex / postsynapse to nucleus signaling pathway / fertilization / chloride transport / vacuolar acidification / nuclear import signal receptor activity / nuclear localization sequence binding / branching morphogenesis of an epithelial tube / NLS-bearing protein import into nucleus / chloride channel activity / regulation of cytoskeleton organization / chloride channel complex / microvillus / keratinocyte differentiation / cellular response to calcium ion / negative regulation of cell migration / cytoplasmic vesicle membrane / multicellular organism growth / nuclear matrix / cytoplasmic stress granule / protein import into nucleus / host cell / cell-cell junction / actin cytoskeleton / apical part of cell / midbody / angiogenesis / DNA-binding transcription factor binding / postsynaptic density / cell differentiation / centrosome / glutamatergic synapse / perinuclear region of cytoplasm / cell surface / mitochondrion / extracellular exosome / nucleoplasm / membrane / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能 Intracellular chloride channel / Glutathione S-transferase, N-terminal domain / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. ... Intracellular chloride channel / Glutathione S-transferase, N-terminal domain / Importin subunit alpha / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain superfamily / Importin beta binding domain / Atypical Arm repeat / Importin-alpha, importin-beta-binding domain / IBB domain profile. / Armadillo/plakoglobin ARM repeat profile. / Armadillo/beta-catenin-like repeat / Armadillo/beta-catenin-like repeats / Armadillo / Leucine-rich Repeat Variant / Leucine-rich Repeat Variant / Glutathione transferase family / Glutathione S-transferase, C-terminal-like / Soluble glutathione S-transferase C-terminal domain profile. / Glutathione S-transferase, N-terminal / Glutathione S-transferase, C-terminal domain superfamily / Armadillo-like helical / Alpha Horseshoe / Thioredoxin-like superfamily / Armadillo-type fold / Mainly Alpha 類似検索 - ドメイン・相同性 Importin subunit alpha-1 / Chloride intracellular channel protein 4 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2 Å 詳細データ登録者 Mynott, A.V. / Brown, L.J. / Harrop, S.J. / Curmi, P.M.G. 引用ジャーナル : Febs J. / 年 : 2011タイトル : Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4著者 : Mynott, A.V. / Harrop, S.J. / Brown, L.J. / Breit, S.N. / Kobe, B. / Curmi, P.M.G. 履歴 登録 2010年9月3日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2011年7月27日 Provider : repository / タイプ : Initial release改定 1.1 2023年11月1日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details
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