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- EMDB-3850: STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFII... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-3850
タイトルSTRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR
マップデータTranscription initiation complex including Pol II, TBP, the transcription factors TFIIA, -B, -E, -F and -H and core Mediator
試料
  • 複合体: Pre-Initiation Complex with core Mediator (PIC-cMed)
    • 複合体: DNA-directed RNA polymerase
      • タンパク質・ペプチド: x 13種
    • 複合体: RNA polymerase II transcription factor B
      • タンパク質・ペプチド: x 23種
    • 複合体: Mediator of RNA polymerase II transcription
      • タンパク質・ペプチド: x 8種
    • 複合体: DNA
      • DNA: x 2種
  • リガンド: x 3種
キーワードtranscription initiation / TRANSCRIPTION / macromolecular complex
機能・相同性
機能・相同性情報


meiotic gene conversion / regulation of mitotic recombination / RNA polymerase II promoter clearance / RNA polymerase II complex recruiting activity / transcription open complex formation at RNA polymerase II promoter / TFIIA-class transcription factor complex binding / RNA polymerase III transcription regulatory region sequence-specific DNA binding / TFIIH-class transcription factor complex binding / phosphatidylinositol-5-phosphate binding / RNA polymerase III preinitiation complex assembly ...meiotic gene conversion / regulation of mitotic recombination / RNA polymerase II promoter clearance / RNA polymerase II complex recruiting activity / transcription open complex formation at RNA polymerase II promoter / TFIIA-class transcription factor complex binding / RNA polymerase III transcription regulatory region sequence-specific DNA binding / TFIIH-class transcription factor complex binding / phosphatidylinositol-5-phosphate binding / RNA polymerase III preinitiation complex assembly / transcription factor TFIIIB complex / positive regulation of mitotic recombination / nucleotide-excision repair factor 3 complex / RNA polymerase I general transcription initiation factor binding / core mediator complex / transcription factor TFIIE complex / nucleotide-excision repair, preincision complex assembly / DNA translocase activity / negative regulation of ribosomal protein gene transcription by RNA polymerase II / regulation of transcription by RNA polymerase III / transcription factor TFIIK complex / TFIIF-class transcription factor complex binding / transcriptional start site selection at RNA polymerase II promoter / RPB4-RPB7 complex / transcription factor TFIIF complex / DNA 5'-3' helicase / mediator complex / phosphatidylinositol-3-phosphate binding / transcription factor TFIIA complex / RNA polymerase I preinitiation complex assembly / transcription factor TFIIH core complex / transcription factor TFIIH holo complex / cyclin-dependent protein serine/threonine kinase activator activity / nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / DNA binding, bending / RNA Polymerase I Transcription Initiation / transcription preinitiation complex / 3'-5' DNA helicase activity / Processing of Capped Intron-Containing Pre-mRNA / DNA 3'-5' helicase / RNA Polymerase III Transcription Initiation From Type 2 Promoter / poly(A)+ mRNA export from nucleus / RNA Pol II CTD phosphorylation and interaction with CE / Formation of the Early Elongation Complex / mRNA Capping / RNA polymerase II transcribes snRNA genes / termination of RNA polymerase II transcription / TP53 Regulates Transcription of DNA Repair Genes / RNA Polymerase II Promoter Escape / RNA Polymerase II Transcription Pre-Initiation And Promoter Opening / RNA Polymerase II Transcription Initiation / RNA Polymerase II Transcription Initiation And Promoter Clearance / termination of RNA polymerase III transcription / RNA polymerase II general transcription initiation factor activity / transcription factor TFIID complex / RNA Polymerase II Pre-transcription Events / RNA-templated transcription / positive regulation of nuclear-transcribed mRNA poly(A) tail shortening / Formation of TC-NER Pre-Incision Complex / RNA Polymerase I Promoter Escape / transcription initiation at RNA polymerase III promoter / termination of RNA polymerase I transcription / nucleolar large rRNA transcription by RNA polymerase I / Gap-filling DNA repair synthesis and ligation in TC-NER / transcription initiation at RNA polymerase I promoter / ATPase activator activity / RNA polymerase II complex binding / Estrogen-dependent gene expression / TFIID-class transcription factor complex binding / TFIIB-class transcription factor binding / maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II / nuclear-transcribed mRNA catabolic process / positive regulation of translational initiation / protein phosphatase activator activity / Dual incision in TC-NER / ATP-dependent activity, acting on DNA / positive regulation of transcription initiation by RNA polymerase II / cellular response to nutrient levels / transcription by RNA polymerase III / translesion synthesis / transcription by RNA polymerase I / RNA polymerase I complex / transcription elongation by RNA polymerase I / RNA polymerase III complex / transcription-coupled nucleotide-excision repair / RNA polymerase II core promoter sequence-specific DNA binding / RNA polymerase II, core complex / DNA helicase activity / tRNA transcription by RNA polymerase III / : / RNA polymerase II preinitiation complex assembly / translation initiation factor binding / TBP-class protein binding / DNA-directed RNA polymerase activity / isomerase activity / nucleotide-excision repair / positive regulation of transcription elongation by RNA polymerase II / transcription coregulator activity / transcription initiation at RNA polymerase II promoter / DNA-templated transcription initiation
類似検索 - 分子機能
Mediator complex, subunit Med19, fungi / Rox3 mediator complex subunit / Mediator of RNA polymerase II transcription subunit 22, Saccharomycetes / Mediator of RNA polymerase II transcription subunit 20 / Mediator complex, subunit Med6, fungi / Mediator complex, subunit Med10 / Transcription factor subunit Med10 of Mediator complex / Mediator of RNA polymerase II transcription subunit 9 / RNA polymerase II transcription mediator complex subunit 9 / Mediator complex, subunit Med4 ...Mediator complex, subunit Med19, fungi / Rox3 mediator complex subunit / Mediator of RNA polymerase II transcription subunit 22, Saccharomycetes / Mediator of RNA polymerase II transcription subunit 20 / Mediator complex, subunit Med6, fungi / Mediator complex, subunit Med10 / Transcription factor subunit Med10 of Mediator complex / Mediator of RNA polymerase II transcription subunit 9 / RNA polymerase II transcription mediator complex subunit 9 / Mediator complex, subunit Med4 / Vitamin-D-receptor interacting Mediator subunit 4 / : / Tfa2 E-tether / Mediator complex, subunit Med31 / Mediator complex, subunit Med21 / Mediator of RNA polymerase II, subunit Med31 superfamily / SOH1 / Subunit 21 of Mediator complex / Mediator complex, subunit Med7 / Mediator complex, subunit Med7/Med21-like / Mediator complex, subunit Med7 superfmaily / : / MED7 protein / Mediator complex, subunit Med20 / Mediator complex, subunit Med14 / TATA-binding related factor (TRF) of subunit 20 of Mediator complex / Mediator complex subunit MED14 / Mediator complex, subunit Med6 / Mediator complex, subunit Med17 / Mediator complex, subunit Med6 superfamily / MED6 mediator sub complex component / Subunit 17 of Mediator complex / Mediator of RNA polymerase II transcription subunit 22 / Mediator complex, subunit Med8, fungi/metazoa / Mediator complex, subunit Med11 / Surfeit locus protein 5 subunit 22 of Mediator complex / Mediator of RNA polymerase II transcription complex subunit 8 / Mediator complex protein / Mediator complex, subunit Med18 / Bacterial type XPD DNA helicase, FeS cluster domain / Med18 protein / TFIIH subunit Tfb4/GTF2H3 / Transcription factor Tfb4 / TFIIH C1-like domain / Ssl1-like / TFIIH subunit Ssl1/p44 / Ssl1-like / TFIIH C1-like domain / TFIIH C1-like domain / TFIIH p62 subunit, N-terminal / TFIIH subunit Tfb1/GTF2H1 / TFIIH p62 subunit, N-terminal domain / BSD domain / BSD domain superfamily / BSD domain / BSD domain profile. / domain in transcription factors and synapse-associated proteins / RAD3/XPD family / Helicase XPB/Ssl2 / ERCC3/RAD25/XPB helicase, C-terminal domain / Helicase XPB/Ssl2, N-terminal domain / Helicase conserved C-terminal domain / ERCC3/RAD25/XPB C-terminal helicase / Helical and beta-bridge domain / Helical and beta-bridge domain / Transcription factor TFIIH subunit p52/Tfb2 / Transcription factor Tfb2, C-terminal domain / Transcription factor Tfb2 / Transcription factor Tfb2 (p52) C-terminal domain / Transcription factor TFIIE beta subunit, DNA-binding domain / TFIIH subunit TTDA/Tfb5 / Transcription initiation factor TFIIE, beta subunit / TFB5-like superfamily / TFA2, Winged helix domain 2 / TFIIE beta subunit core domain / Transcription factor TFIIH complex subunit Tfb5 / TFA2 Winged helix domain 2 / TFIIE beta central core DNA-binding domain profile. / Transcription factor TFIIH complex subunit Tfb5 / Cdk-activating kinase assembly factor MAT1/Tfb3 / Cdk-activating kinase assembly factor MAT1, centre / CDK-activating kinase assembly factor MAT1 / Zinc finger, C3HC4 type (RING finger) / ATP-dependent helicase Rad3/Chl1-like / : / Helicase-like, DEXD box c2 type / DEAD2 / DEAD_2 / DEXDc2 / Helicase superfamily 1/2, DinG/Rad3-like / HELICc2 / ATP-dependent helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type / Helicase C-terminal domain / Superfamilies 1 and 2 helicase ATP-binding type-2 domain profile. / Transcription initiation factor IIE subunit alpha, N-terminal / Transcription factor TFE/TFIIEalpha HTH domain / TFIIEalpha/SarR/Rpc3 HTH domain / Transcription factor E / TFIIE alpha subunit
類似検索 - ドメイン・相同性
: / : / DNA-directed RNA polymerase II subunit RPB1 / General transcription and DNA repair factor IIH helicase subunit XPD/RAD3 / DNA-directed RNA polymerase II subunit RPB2 / TATA-box-binding protein / DNA-directed RNA polymerase II subunit RPB3 / Mediator of RNA polymerase II transcription subunit 14 / DNA-directed RNA polymerase II subunit RPB4 / DNA-directed RNA polymerases I, II, and III subunit RPABC1 ...: / : / DNA-directed RNA polymerase II subunit RPB1 / General transcription and DNA repair factor IIH helicase subunit XPD/RAD3 / DNA-directed RNA polymerase II subunit RPB2 / TATA-box-binding protein / DNA-directed RNA polymerase II subunit RPB3 / Mediator of RNA polymerase II transcription subunit 14 / DNA-directed RNA polymerase II subunit RPB4 / DNA-directed RNA polymerases I, II, and III subunit RPABC1 / DNA-directed RNA polymerases I, II, and III subunit RPABC2 / DNA-directed RNA polymerases I, II, and III subunit RPABC3 / DNA-directed RNA polymerases I, II, and III subunit RPABC5 / Mediator of RNA polymerase II transcription subunit 19 / DNA-directed RNA polymerase II subunit RPB9 / Transcription initiation factor IIB / Mediator of RNA polymerase II transcription subunit 17 / Mediator of RNA polymerase II transcription subunit 22 / Mediator of RNA polymerase II transcription subunit 18 / Transcription initiation factor IIA large subunit / Transcription initiation factor IIA subunit 2 / General transcription and DNA repair factor IIH subunit TFB1 / Mediator of RNA polymerase II transcription subunit 9 / DNA-directed RNA polymerase II subunit RPB7 / Mediator of RNA polymerase II transcription subunit 20 / Transcription initiation factor IIE subunit alpha / Transcription initiation factor IIE subunit beta / Mediator of RNA polymerase II transcription subunit 8 / Mediator of RNA polymerase II transcription subunit 31 / Mediator of RNA polymerase II transcription subunit 6 / DNA-directed RNA polymerase II subunit RPB11 / DNA-directed RNA polymerases I, II, and III subunit RPABC4 / Transcription initiation factor IIF subunit alpha / Transcription initiation factor IIF subunit beta / Mediator of RNA polymerase II transcription subunit 21 / General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 / General transcription and DNA repair factor IIH subunit TFB2 / RNA polymerase II transcription factor B subunit 3 / General transcription and DNA repair factor IIH subunit SSL1 / Mediator of RNA polymerase II transcription subunit 10 / Mediator of RNA polymerase II transcription subunit 7 / General transcription and DNA repair factor IIH subunit TFB4 / Mediator of RNA polymerase II transcription subunit 4 / General transcription and DNA repair factor IIH subunit TFB5 / Mediator of RNA polymerase II transcription subunit 11
類似検索 - 構成要素
生物種Saccharomyces cerevisiae (パン酵母) / synthetic construct (人工物) / Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 5.8 Å
データ登録者Schilbach S / Hantsche M / Tegunov D / Dienemann C / Wigge C / Urlaub H / Cramer P
資金援助 ドイツ, 4件
OrganizationGrant number国
European Research Council693023 ドイツ
German Research FoundationSFB860 ドイツ
German Research FoundationSPP1935 ドイツ
Volkswagen Foundation ドイツ
引用ジャーナル: Nature / 年: 2017
タイトル: Structures of transcription pre-initiation complex with TFIIH and Mediator.
著者: S Schilbach / M Hantsche / D Tegunov / C Dienemann / C Wigge / H Urlaub / P Cramer /
要旨: For the initiation of transcription, RNA polymerase II (Pol II) assembles with general transcription factors on promoter DNA to form the pre-initiation complex (PIC). Here we report cryo-electron ...For the initiation of transcription, RNA polymerase II (Pol II) assembles with general transcription factors on promoter DNA to form the pre-initiation complex (PIC). Here we report cryo-electron microscopy structures of the Saccharomyces cerevisiae PIC and PIC-core Mediator complex at nominal resolutions of 4.7 Å and 5.8 Å, respectively. The structures reveal transcription factor IIH (TFIIH), and suggest how the core and kinase TFIIH modules function in the opening of promoter DNA and the phosphorylation of Pol II, respectively. The TFIIH core subunit Ssl2 (a homologue of human XPB) is positioned on downstream DNA by the 'E-bridge' helix in TFIIE, consistent with TFIIE-stimulated DNA opening. The TFIIH kinase module subunit Tfb3 (MAT1 in human) anchors the kinase Kin28 (CDK7), which is mobile in the PIC but preferentially located between the Mediator hook and shoulder in the PIC-core Mediator complex. Open spaces between the Mediator head and middle modules may allow access of the kinase to its substrate, the C-terminal domain of Pol II.
履歴
登録2017年8月13日-
ヘッダ(付随情報) 公開2018年5月9日-
マップ公開2018年5月9日-
更新2024年5月15日-
現状2024年5月15日処理サイト: PDBe / 状態: 公開

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構造の表示

ムービー
  • 表面図（断面を密度値に従い着色）
  • 表面レベル: 0.08
  • UCSF Chimeraによる作画
  • ダウンロード
  • 表面図（半径に従い着色）
  • 表面レベル: 0.08
  • UCSF Chimeraによる作画
  • ダウンロード
  • あてはめたモデルとの重ね合わせ
  • 原子モデル: PDB-5oqm
  • 表面レベル: 0.08
  • UCSF Chimeraによる作画
  • ダウンロード
ムービービューア
構造ビューアEMマップ:
SurfViewMolmilJmol/JSmol
添付画像

emd_3850.png

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マップ

ファイルダウンロード / ファイル: emd_3850.map.gz / 形式: CCP4 / 大きさ: 163.6 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈Transcription initiation complex including Pol II, TBP, the transcription factors TFIIA, -B, -E, -F and -H and core Mediator
投影像・断面図

画像のコントロール

大きさ
明度
コントラスト
その他
軸Z (Sec.)Y (Row.)X (Col.)
1.37 Å/pix.
x 350 pix.
= 479.5 Å		1.37 Å/pix.
x 350 pix.
= 479.5 Å		1.37 Å/pix.
x 350 pix.
= 479.5 Å

表面

投影像

断面 (1/3)

断面 (1/2)

断面 (2/3)

画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.37 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.08 / ムービー #1: 0.08
最小 - 最大-0.33997163 - 0.6997163
平均 (標準偏差)0.0008746041 (±0.024196334)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ350350350
Spacing350350350
セルA=B=C: 479.5 Å
α=β=γ: 90.0 °

CCP4マップ ヘッダ情報:

modeImage stored as Reals
Å/pix. X/Y/Z1.371.371.37
M x/y/z350350350
origin x/y/z0.0000.0000.000
length x/y/z479.500479.500479.500
α/β/γ90.00090.00090.000
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS350350350
D min/max/mean-0.3400.7000.001

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添付データ

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試料の構成要素

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全体 : Pre-Initiation Complex with core Mediator (PIC-cMed)

全体名称: Pre-Initiation Complex with core Mediator (PIC-cMed)
要素
  • 複合体: Pre-Initiation Complex with core Mediator (PIC-cMed)
    • 複合体: DNA-directed RNA polymerase
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB1
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB2
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB3
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB4
      • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC1
      • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC2
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB7
      • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC3
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB9
      • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC5
      • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB11
      • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC4
      • タンパク質・ペプチド: Unknown protein
    • 複合体: RNA polymerase II transcription factor B
      • タンパク質・ペプチド: Transcription initiation factor IIB
      • タンパク質・ペプチド: TATA-box-binding protein
      • タンパク質・ペプチド: Transcription initiation factor IIF subunit alpha
      • タンパク質・ペプチド: Transcription initiation factor IIF subunit beta
      • タンパク質・ペプチド: Transcription initiation factor IIA large subunit
      • タンパク質・ペプチド: Transcription initiation factor IIA subunit 2
      • タンパク質・ペプチド: Transcription factor TFIIE subunit
      • タンパク質・ペプチド: Transcription initiation factor IIE subunit beta
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 6
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 8
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 11
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 17
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 18
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 20
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 22
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 4
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 7
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 9
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 10
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 14
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 19
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 21
      • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 31,Mediator of RNA polymerase II transcription subunit 31
    • 複合体: Mediator of RNA polymerase II transcription
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH helicase subunit XPD
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH subunit TFB1
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH subunit TFB2
      • タンパク質・ペプチド: RNA polymerase II transcription factor B subunit 3
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH subunit TFB4
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH subunit TFB5
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH subunit SSL1
      • タンパク質・ペプチド: General transcription and DNA repair factor IIH helicase subunit XPB
    • 複合体: DNA
      • DNA: NONTEMPLATE DNA
      • DNA: TEMPLATE DNA
  • リガンド: ZINC ION
  • リガンド: MAGNESIUM ION
  • リガンド: IRON/SULFUR CLUSTER

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超分子 #1: Pre-Initiation Complex with core Mediator (PIC-cMed)

超分子名称: Pre-Initiation Complex with core Mediator (PIC-cMed)
タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#46
分子量理論値: 1.95 MDa

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超分子 #2: DNA-directed RNA polymerase

超分子名称: DNA-directed RNA polymerase / タイプ: complex / ID: 2 / 親要素: 1 / 含まれる分子: #1-#12, #31
由来(天然)生物種: Saccharomyces cerevisiae (パン酵母)

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超分子 #3: RNA polymerase II transcription factor B

超分子名称: RNA polymerase II transcription factor B / タイプ: complex / ID: 3 / 親要素: 1 / 含まれる分子: #13, #15-#17, #19-#22, #32-#46
由来(天然)生物種: Saccharomyces cerevisiae (パン酵母)

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超分子 #4: Mediator of RNA polymerase II transcription

超分子名称: Mediator of RNA polymerase II transcription / タイプ: complex / ID: 4 / 親要素: 1 / 含まれる分子: #23-#30
由来(天然)生物種: Saccharomyces cerevisiae (パン酵母)

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超分子 #5: DNA

超分子名称: DNA / タイプ: complex / ID: 5 / 親要素: 1 / 含まれる分子: #14, #18
由来(天然)生物種: synthetic construct (人工物)

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分子 #1: DNA-directed RNA polymerase II subunit RPB1

分子名称: DNA-directed RNA polymerase II subunit RPB1 / タイプ: protein_or_peptide / ID: 1 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA-directed RNA polymerase
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 191.821578 KDa
配列文字列: MVGQQYSSAP LRTVKEVQFG LFSPEEVRAI SVAKIRFPET MDETQTRAKI GGLNDPRLGS IDRNLKCQTC QEGMNECPGH FGHIDLAKP VFHVGFIAKI KKVCECVCMH CGKLLLDEHN ELMRQALAIK DSKKRFAAIW TLCKTKMVCE TDVPSEDDPT Q LVSRGGCG ...文字列:
MVGQQYSSAP LRTVKEVQFG LFSPEEVRAI SVAKIRFPET MDETQTRAKI GGLNDPRLGS IDRNLKCQTC QEGMNECPGH FGHIDLAKP VFHVGFIAKI KKVCECVCMH CGKLLLDEHN ELMRQALAIK DSKKRFAAIW TLCKTKMVCE TDVPSEDDPT Q LVSRGGCG NTQPTIRKDG LKLVGSWKKD RATGDADEPE LRVLSTEEIL NIFKHISVKD FTSLGFNEVF SRPEWMILTC LP VPPPPVR PSISFNESQR GEDDLTFKLA DILKANISLE TLEHNGAPHH AIEEAESLLQ FHVATYMDND IAGQPQALQK SGR PVKSIR ARLKGKEGRI RGNLMGKRVD FSARTVISGD PNLELDQVGV PKSIAKTLTY PEVVTPYNID RLTQLVRNGP NEHP GAKYV IRDSGDRIDL RYSKRAGDIQ LQYGWKVERH IMDNDPVLFN RQPSLHKMSM MAHRVKVIPY STFRLNLSVT SPYNA DFDG DEMNLHVPQS EETRAELSQL CAVPLQIVSP QSNKPCMGIV QDTLCGIRKL TLRDTFIELD QVLNMLYWVP DWDGVI PTP AIIKPKPLWS GKQILSVAIP NGIHLQRFDE GTTLLSPKDN GMLIIDGQII FGVVEKKTVG SSNGGLIHVV TREKGPQ VC AKLFGNIQKV VNFWLLHNGF STGIGDTIAD GPTMREITET IAEAKKKVLD VTKEAQANLL TAKHGMTLRE SFEDNVVR F LNEARDKAGR LAEVNLKDLN NVKQMVMAGS KGSFINIAQM SACVGQQSVE GKRIAFGFVD RTLPHFSKDD YSPESKGFV ENSYLRGLTP QEFFFHAMGG REGLIDTAVK TAETGYIQRR LVKALEDIMV HYDNTTRNSL GNVIQFIYGE DGMDAAHIEK QSLDTIGGS DAAFEKRYRV DLLNTDHTLD PSLLESGSEI LGDLKLQVLL DEEYKQLVKD RKFLREVFVD GEANWPLPVN I RRIIQNAQ QTFHIDHTKP SDLTIKDIVL GVKDLQENLL VLRGKNEIIQ NAQRDAVTLF CCLLRSRLAT RRVLQEYRLT KQ AFDWVLS NIEAQFLRSV VHPGEMVGVL AAQSIGEPAT QMTLNTFHFA GVASKKVTSG VPRLKEILNV AKNMKTPSLT VYL EPGHAA DQEQAKLIRS AIEHTTLKSV TIASEIYYDP DPRSTVIPED EEIIQLHFSL LDEEAEQSFD QQSPWLLRLE LDRA AMNDK DLTMGQVGER IKQTFKNDLF VIWSEDNDEK LIIRCRVVRP KSLDAETEAE EDHMLKKIEN TMLENITLRG VENIE RVVM MKYDRKVPSP TGEYVKEPEW VLETDGVNLS EVMTVPGIDP TRIYTNSFID IMEVLGIEAG RAALYKEVYN VIASDG SYV NYRHMALLVD VMTTQGGLTS VTRHGFNRSN TGALMRCSFE ETVEILFEAG ASAELDDCRG VSENVILGQM APIGTGA FD VMIDEESLVK YMPEQKITEI EDGQDGGVTP YSNESGLVNA DLDVKDELMF SPLVDSGSND AMAGGFTAYG GADYGEAT S PFGAYGEAPT SPGFGVSSPG FSPTSPTYSP TSPAYSPTSP SYSPTSPSYS PTSPSYSPTS PSYSPTSPSY SPTSPSYSP TSPSYSPTSP SYSPTSPSYS PTSPSYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPA YSPTSPSYSP TSPSYSPTSP SYSPTSPSY SPTSPNYSPT SPSYSPTSPG YSPGSPAYSP KQDEQKHNEN ENSR

UniProtKB: DNA-directed RNA polymerase II subunit RPB1

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分子 #2: DNA-directed RNA polymerase II subunit RPB2

分子名称: DNA-directed RNA polymerase II subunit RPB2 / タイプ: protein_or_peptide / ID: 2 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA-directed RNA polymerase
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 138.937297 KDa
配列文字列: MSDLANSEKY YDEDPYGFED ESAPITAEDS WAVISAFFRE KGLVSQQLDS FNQFVDYTLQ DIICEDSTLI LEQLAQHTTE SDNISRKYE ISFGKIYVTK PMVNESDGVT HALYPQEARL RNLTYSSGLF VDVKKRTYEA IDVPGRELKY ELIAEESEDD S ESGKVFIG ...文字列:
MSDLANSEKY YDEDPYGFED ESAPITAEDS WAVISAFFRE KGLVSQQLDS FNQFVDYTLQ DIICEDSTLI LEQLAQHTTE SDNISRKYE ISFGKIYVTK PMVNESDGVT HALYPQEARL RNLTYSSGLF VDVKKRTYEA IDVPGRELKY ELIAEESEDD S ESGKVFIG RLPIMLRSKN CYLSEATESD LYKLKECPFD MGGYFIINGS EKVLIAQERS AGNIVQVFKK AAPSPISHVA EI RSALEKG SRFISTLQVK LYGREGSSAR TIKATLPYIK QDIPIVIIFR ALGIIPDGEI LEHICYDVND WQMLEMLKPC VED GFVIQD RETALDFIGR RGTALGIKKE KRIQYAKDIL QKEFLPHITQ LEGFESRKAF FLGYMINRLL LCALDRKDQD DRDH FGKKR LDLAGPLLAQ LFKTLFKKLT KDIFRYMQRT VEEAHDFNMK LAINAKTITS GLKYALATGN WGEQKKAMSS RAGVS QVLN RYTYSSTLSH LRRTNTPIGR DGKLAKPRQL HNTHWGLVCP AETPEGQACG LVKNLSLMSC ISVGTDPMPI ITFLSE WGM EPLEDYVPHQ SPDATRVFVN GVWHGVHRNP ARLMETLRTL RRKGDINPEV SMIRDIREKE LKIFTDAGRV YRPLFIV ED DESLGHKELK VRKGHIAKLM ATEYQDIEGG FEDVEEYTWS SLLNEGLVEY IDAEEEESIL IAMQPEDLEP AEANEEND L DVDPAKRIRV SHHATTFTHC EIHPSMILGV AASIIPFPDH NQSPRNTYQS AMGKQAMGVF LTNYNVRMDT MANILYYPQ KPLGTTRAME YLKFRELPAG QNAIVAIACY SGYNQEDSMI MNQSSIDRGL FRSLFFRSYM DQEKKYGMSI TETFEKPQRT NTLRMKHGT YDKLDDDGLI APGVRVSGED VIIGKTTPIS PDEEELGQRT AYHSKRDAST PLRSTENGIV DQVLVTTNQD G LKFVKVRV RTTKIPQIGD KFASRHGQKG TIGITYRRED MPFTAEGIVP DLIINPHAIP SRMTVAHLIE CLLSKVAALS GN EGDASPF TDITVEGISK LLREHGYQSR GFEVMYNGHT GKKLMAQIFF GPTYYQRLRH MVDDKIHARA RGPMQVLTRQ PVE GRSRDG GLRFGEMERD CMIAHGAASF LKERLMEASD AFRVHICGIC GLMTVIAKLN HNQFECKGCD NKIDIYQIHI PYAA KLLFQ ELMAMNITPR LYTDRSRDF

UniProtKB: DNA-directed RNA polymerase II subunit RPB2

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分子 #3: DNA-directed RNA polymerase II subunit RPB3

分子名称: DNA-directed RNA polymerase II subunit RPB3 / タイプ: protein_or_peptide / ID: 3 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 35.330457 KDa
配列文字列: MSEEGPQVKI REASKDNVDF ILSNVDLAMA NSLRRVMIAE IPTLAIDSVE VETNTTVLAD EFIAHRLGLI PLQSMDIEQL EYSRDCFCE DHCDKCSVVL TLQAFGESES TTNVYSKDLV IVSNLMGRNI GHPIIQDKEG NGVLICKLRK GQELKLTCVA K KGIAKEHA ...文字列:
MSEEGPQVKI REASKDNVDF ILSNVDLAMA NSLRRVMIAE IPTLAIDSVE VETNTTVLAD EFIAHRLGLI PLQSMDIEQL EYSRDCFCE DHCDKCSVVL TLQAFGESES TTNVYSKDLV IVSNLMGRNI GHPIIQDKEG NGVLICKLRK GQELKLTCVA K KGIAKEHA KWGPAAAIEF EYDPWNKLKH TDYWYEQDSA KEWPQSKNCE YEDPPNEGDP FDYKAQADTF YMNVESVGSI PV DQVVVRG IDTLQKKVAS ILLALTQMDQ DKVNFASGDN NTASNMLGSN EDVMMTGAEQ DPYSNASQMG NTGSGGYDNA W

UniProtKB: DNA-directed RNA polymerase II subunit RPB3

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分子 #4: DNA-directed RNA polymerase II subunit RPB4

分子名称: DNA-directed RNA polymerase II subunit RPB4 / タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 25.451191 KDa
配列文字列: MNVSTSTFQT RRRRLKKVEE EENAATLQLG QEFQLKQINH QGEEEELIAL NLSEARLVIK EALVERRRAF KRSQKKHKKK HLKHENAND ETTAVEDEDD DLDEDDVNAD DDDFMHSETR EKELESIDVL LEQTTGGNNK DLKNTMQYLT NFSRFRDQET V GAVIQLLK ...文字列:
MNVSTSTFQT RRRRLKKVEE EENAATLQLG QEFQLKQINH QGEEEELIAL NLSEARLVIK EALVERRRAF KRSQKKHKKK HLKHENAND ETTAVEDEDD DLDEDDVNAD DDDFMHSETR EKELESIDVL LEQTTGGNNK DLKNTMQYLT NFSRFRDQET V GAVIQLLK STGLHPFEVA QLGSLACDTA DEAKTLIPSL NNKISDDELE RILKELSNLE TLY

UniProtKB: DNA-directed RNA polymerase II subunit RPB4

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分子 #5: DNA-directed RNA polymerases I, II, and III subunit RPABC1

分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC1
タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 25.117094 KDa
配列文字列: MDQENERNIS RLWRAFRTVK EMVKDRGYFI TQEEVELPLE DFKAKYCDSM GRPQRKMMSF QANPTEESIS KFPDMGSLWV EFCDEPSVG VKTMKTFVIH IQEKNFQTGI FVYQNNITPS AMKLVPSIPP ATIETFNEAA LVVNITHHEL VPKHIRLSSD E KRELLKRY ...文字列:
MDQENERNIS RLWRAFRTVK EMVKDRGYFI TQEEVELPLE DFKAKYCDSM GRPQRKMMSF QANPTEESIS KFPDMGSLWV EFCDEPSVG VKTMKTFVIH IQEKNFQTGI FVYQNNITPS AMKLVPSIPP ATIETFNEAA LVVNITHHEL VPKHIRLSSD E KRELLKRY RLKESQLPRI QRADPVALYL GLKRGEVVKI IRKSETSGRY ASYRICM

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC1

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分子 #6: DNA-directed RNA polymerases I, II, and III subunit RPABC2

分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC2
タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 17.931834 KDa
配列文字列:
MSDYEEAFND GNENFEDFDV EHFSDEETYE EKPQFKDGET TDANGKTIVT GGNGPEDFQQ HEQIRRKTLK EKAIPKDQRA TTPYMTKYE RARILGTRAL QISMNAPVFV DLEGETDPLR IAMKELAEKK IPLVIRRYLP DGSFEDWSVE ELIVDL

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC2

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分子 #7: DNA-directed RNA polymerase II subunit RPB7

分子名称: DNA-directed RNA polymerase II subunit RPB7 / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 19.081053 KDa
配列文字列:
MFFIKDLSLN ITLHPSFFGP RMKQYLKTKL LEEVEGSCTG KFGYILCVLD YDNIDIQRGR ILPTDGSAEF NVKYRAVVFK PFKGEVVDG TVVSCSQHGF EVQVGPMKVF VTKHLMPQDL TFNAGSNPPS YQSSEDVITI KSRIRVKIEG CISQVSSIHA I GSIKEDYL GAI

UniProtKB: DNA-directed RNA polymerase II subunit RPB7

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分子 #8: DNA-directed RNA polymerases I, II, and III subunit RPABC3

分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC3
タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 16.525363 KDa
配列文字列:
MSNTLFDDIF QVSEVDPGRY NKVCRIEAAS TTQDQCKLTL DINVELFPVA AQDSLTVTIA SSLNLEDTPA NDSSATRSWR PPQAGDRSL ADDYDYVMYG TAYKFEEVSK DLIAVYYSFG GLLMRLEGNY RNLNNLKQEN AYLLIRR

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC3

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分子 #9: DNA-directed RNA polymerase II subunit RPB9

分子名称: DNA-directed RNA polymerase II subunit RPB9 / タイプ: protein_or_peptide / ID: 9 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 14.308161 KDa
配列文字列:
MTTFRFCRDC NNMLYPREDK ENNRLLFECR TCSYVEEAGS PLVYRHELIT NIGETAGVVQ DIGSDPTLPR SDRECPKCHS RENVFFQSQ QRRKDTSMVL FFVCLSCSHI FTSDQKNKRT QFS

UniProtKB: DNA-directed RNA polymerase II subunit RPB9

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分子 #10: DNA-directed RNA polymerases I, II, and III subunit RPABC5

分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC5
タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 8.290732 KDa
配列文字列:
MIVPVRCFSC GKVVGDKWES YLNLLQEDEL DEGTALSRLG LKRYCCRRMI LTHVDLIEKF LRYNPLEKRD

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC5

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分子 #11: DNA-directed RNA polymerase II subunit RPB11

分子名称: DNA-directed RNA polymerase II subunit RPB11 / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 13.633493 KDa
配列文字列:
MNAPDRFELF LLGEGESKLK IDPDTKAPNA VVITFEKEDH TLGNLIRAEL LNDRKVLFAA YKVEHPFFAR FKLRIQTTEG YDPKDALKN ACNSIINKLG ALKTNFETEW NLQTLAADDA F

UniProtKB: DNA-directed RNA polymerase II subunit RPB11

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分子 #12: DNA-directed RNA polymerases I, II, and III subunit RPABC4

分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC4
タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 7.729969 KDa
配列文字列:
MSREGFQIPT NLDAAAAGTS QARTATLKYI CAECSSKLSL SRTDAVRCKD CGHRILLKAR TKRLVQFEAR

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC4

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分子 #13: Transcription initiation factor IIB

分子名称: Transcription initiation factor IIB / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 38.25734 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MMTRESIDKR AGRRGPNLNI VLTCPECKVY PPKIVERFSE GDVVCALCGL VLSDKLVDTR SEWRTFSNDD HNGDDPSRVG EASNPLLDG NNLSTRIGKG ETTDMRFTKE LNKAQGKNVM DKKDNEVQAA FAKITMLCDA AELPKIVKDC AKEAYKLCHD E KTLKGKSM ...文字列:
MMTRESIDKR AGRRGPNLNI VLTCPECKVY PPKIVERFSE GDVVCALCGL VLSDKLVDTR SEWRTFSNDD HNGDDPSRVG EASNPLLDG NNLSTRIGKG ETTDMRFTKE LNKAQGKNVM DKKDNEVQAA FAKITMLCDA AELPKIVKDC AKEAYKLCHD E KTLKGKSM ESIMAASILI GCRRAEVART FKEIQSLIHV KTKEFGKTLN IMKNILRGKS EDGFLKIDTD NMSGAQNLTY IP RFCSHLG LPMQVTTSAE YTAKKCKEIK EIAGKSPITI AVVSIYLNIL LFQIPITAAK VGQTLQVTEG TIKSGYKILY EHR DKLVDP QLIANGVVSL DNLPGVEKK

UniProtKB: Transcription initiation factor IIB

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分子 #15: TATA-box-binding protein

分子名称: TATA-box-binding protein / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 27.042275 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MADEERLKEF KEANKIVFDP NTRQVWENQN RDGTKPATTF QSEEDIKRAA PESEKDTSAT SGIVPTLQNI VATVTLGCRL DLKTVALHA RNAEYNPKRF AAVIMRIREP KTTALIFASG KMVVTGAKSE DDSKLASRKY ARIIQKIGFA AKFTDFKIQN I VGSCDVKF ...文字列:
MADEERLKEF KEANKIVFDP NTRQVWENQN RDGTKPATTF QSEEDIKRAA PESEKDTSAT SGIVPTLQNI VATVTLGCRL DLKTVALHA RNAEYNPKRF AAVIMRIREP KTTALIFASG KMVVTGAKSE DDSKLASRKY ARIIQKIGFA AKFTDFKIQN I VGSCDVKF PIRLEGLAFS HGTFSSYEPE LFPGLIYRMV KPKIVLLIFV SGKIVLTGAK QREEIYQAFE AIYPVLSEFR KM

UniProtKB: TATA-box-binding protein

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分子 #16: Transcription initiation factor IIF subunit alpha

分子名称: Transcription initiation factor IIF subunit alpha / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (パン酵母)
分子量理論値: 83.341836 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSRRNPPGSR NGGGPTNASP FIKRDRMRRN FLRMRMGQNG SNSSSPGVPN GDNSRGSLVK KDDPEYAEER EKMLLQIGVE ADAGRSNVK VKDEDPNEYN EFPLRAIPKE DLENMRTHLL KFQSKKKINP VTDFHLPVRL HRKDTRNLQF QLTRAEIVQR Q KEISEYKK ...文字列:
MSRRNPPGSR NGGGPTNASP FIKRDRMRRN FLRMRMGQNG SNSSSPGVPN GDNSRGSLVK KDDPEYAEER EKMLLQIGVE ADAGRSNVK VKDEDPNEYN EFPLRAIPKE DLENMRTHLL KFQSKKKINP VTDFHLPVRL HRKDTRNLQF QLTRAEIVQR Q KEISEYKK KAEQERSTPN SGGMNKSGTV SLNNTVKDGS QTPTVDSVTK DNTANGVNSS IPTVTGSSVP PASPTTVSAV ES NGLSNGS TSAANGLDGN ASTANLANGR PLVTKLEDAG PAEDPTKVGM VKYDGKEVTN EPEFEEGTMD PLADVAPDGG GRA KRGNLR RKTRQLKVLD ENAKKLRFEE FYPWVMEDFD GYNTWVGSYE AGNSDSYVLL SVEDDGSFTM IPADKVYKFT ARNK YAT(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) LTIDEAEKRM DKKSGEV PR WLMKHLDNIG TTTTRYDRTR RKLKAVADQQ AMDEDDRDDN SEVELDYDEE FADDEEAPII DGNEQENKES EQRIKKEM L QANAMGLRDE EAPSENEEDE LFGEKKIDED GERIKKALQK TELAALYSSD ENEINPYLSE SDIENKENES PVKKEEDSD TLSKSKRSSP KKQQKKATNA HVHKEPTLRV KSIKNCVIIL KGDKKILKSF PEGEWNPQTT KAVDSSNNAS NTVPSPIKQE EGLNSTVAE REETPAPTIT EKDIIEAIGD GKVNIKEFGK FIRRKYPGAE NKKLMFAIVK KLCRKVGNDH MELKKE

UniProtKB: Transcription initiation factor IIF subunit alpha, UNIPROTKB: A0A250WD40

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分子 #17: Transcription initiation factor IIF subunit beta

分子名称: Transcription initiation factor IIF subunit beta / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 46.684492 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSSGSAGAPA LSNNSTNSVA KEKSGNISGD EYLSQEEEVF DGNDIENNET KVYEESLDLD LERSNRQVWL VRLPMFLAEK WRDRNNLHG QELGKIRINK DGSKITLLLN ENDNDSIPHE YDLELTKKVV ENEYVFTEQN LKKYQQRKKE LEADPEKQRQ A YLKKQERE ...文字列:
MSSGSAGAPA LSNNSTNSVA KEKSGNISGD EYLSQEEEVF DGNDIENNET KVYEESLDLD LERSNRQVWL VRLPMFLAEK WRDRNNLHG QELGKIRINK DGSKITLLLN ENDNDSIPHE YDLELTKKVV ENEYVFTEQN LKKYQQRKKE LEADPEKQRQ A YLKKQERE EELKKKQQQQ KRRNNRKKFN HRVMTDRDGR DRYIPYVKTI PKKTAIVGTV CHECQVMPSM NDPNYHKIVE QR RNIVKLN NKERITTLDE TVGVTMSHTG MSMRSDNSNF LKVGREKAKS NIKSIRMPKK EILDYLFKLF DEYDYWSLKG LKE RTRQPE AHLKECLDKV ATLVKKGPYA FKYTLRPEYK KLKEEERKAT LGELADEQTG SAGDNAQGDA EADLEDEIEM EDVV

UniProtKB: Transcription initiation factor IIF subunit beta

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分子 #19: Transcription initiation factor IIA large subunit

分子名称: Transcription initiation factor IIA large subunit / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 32.230805 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK VTTFSWDNQF NEGNINGVQN DLNFNLATPG VNSSEFNIK EENTGNEGLI LPNINSNNNI PHSGETNINT NTVEATNNSG ATLNTNTSGN TNADVTSQPK IEVKPEIELT I NNANITTV ...文字列:
MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK VTTFSWDNQF NEGNINGVQN DLNFNLATPG VNSSEFNIK EENTGNEGLI LPNINSNNNI PHSGETNINT NTVEATNNSG ATLNTNTSGN TNADVTSQPK IEVKPEIELT I NNANITTV ENIDDESEKK DDEEKEEDVE KTRKEKEQIE QVKLQAKKEK RSALLDTDEV GSELDDSDDD YLISEGEEDG PD ENLMLCL YDKVTRTKAR WKCSLKDGVV TINRNDYTFQ KAQVEAEWV

UniProtKB: Transcription initiation factor IIA large subunit

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分子 #20: Transcription initiation factor IIA subunit 2

分子名称: Transcription initiation factor IIA subunit 2 / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 13.47307 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MAVPGYYELY RRSTIGNSLV DALDTLISDG RIEASLAMRV LETFDKVVAE TLKDNTQSKL TVKGNLDTYG FCDDVWTFIV KNCQVTVED SHRDASQNGS GDSQSVISVD KLRIVACNSK KSE

UniProtKB: Transcription initiation factor IIA subunit 2

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分子 #21: Transcription factor TFIIE subunit

分子名称: Transcription factor TFIIE subunit / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 59.825934 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MDRPIDDIVK NLLKFVVRGF YGGSFVLVLD AILFHSVLAE DDLKQLLSIN KTELGPLIAR LRSDRLISIH KQREYPPNSK SVERVYYYV KYPHAIDAIK WKVHQVVQRL KDDLDKNSEP NGYMCPICLT KYTQLEAVQL LNFDRTEFLC SLCDEPLVED D SGKKNKEK ...文字列:
MDRPIDDIVK NLLKFVVRGF YGGSFVLVLD AILFHSVLAE DDLKQLLSIN KTELGPLIAR LRSDRLISIH KQREYPPNSK SVERVYYYV KYPHAIDAIK WKVHQVVQRL KDDLDKNSEP NGYMCPICLT KYTQLEAVQL LNFDRTEFLC SLCDEPLVED D SGKKNKEK QDKLNRLMDQ IQPIIDSLKK IDDSRI(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)E ENTFEIALAR LIPPQNQSHA AYTYNPKKGS TMFRPGDSAP LPNLMGTALG NDSSRRAGAN SQATLHINI TTASDEVAQR ELQERQAEEK RKQNAVPEWH KQSTIGKTAL GRLDNEEEFD PVVTASAMDS INPDNEPAQE TSYQNNRTLT EQEMEEREN EKTLNDYYAA LAKKQAKLNK EEEEEEEEEE DEEEEEEEEM EDVMDDNDET ARENALEDEF EDVTDTAGTA K TESNTSND VKQESINDKT EDAVNATATA SGPSANAKPN DGDDDDDDDD DEMDIEFEDV

UniProtKB: UNIPROTKB: A0A250WIP3, Transcription initiation factor IIE subunit alpha

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分子 #22: Transcription initiation factor IIE subunit beta

分子名称: Transcription initiation factor IIE subunit beta / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 37.050434 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSKNRDPLLA NLNAFKSKVK SAPVIAPAKV GQKKTNDTVI TIDGNTRKRT ASERAQENTL NSAKNPVLVD IKKEAGSNSS NAISLDDDD DDEDFGSSPS KKVRPGSIAA AALQANQTDI SKSHDSSKLL WATEYIQKKG KPVLVNELLD YLSMKKDDKV I ELLKKLDR ...文字列:
MSKNRDPLLA NLNAFKSKVK SAPVIAPAKV GQKKTNDTVI TIDGNTRKRT ASERAQENTL NSAKNPVLVD IKKEAGSNSS NAISLDDDD DDEDFGSSPS KKVRPGSIAA AALQANQTDI SKSHDSSKLL WATEYIQKKG KPVLVNELLD YLSMKKDDKV I ELLKKLDR IEFDPKKGTF KYLSTYDVHS PSELLKLLRS QVTFKGISCK DLKDGWPQCD ETINQLEEDS KILVLRTKKD KT PRYVWYN SGGNLKCIDE EFVKMWENVQ LPQFAELPRK LQDLGLKPAS VDPATIKRQT KRVEVKKKRQ RKGKITNTHM TGI LKDYSH RV

UniProtKB: Transcription initiation factor IIE subunit beta

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分子 #23: General transcription and DNA repair factor IIH helicase subunit XPD

分子名称: General transcription and DNA repair factor IIH helicase subunit XPD
タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 89.064555 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MKFYIDDLPV LFPYPKIYPE QYNYMCDIKK TLDVGGNSIL EMPSGTGKTV SLLSLTIAYQ MHYPEHRKII YCSRTMSEIE KALVELENL MDYRTKELGY QEDFRGLGLT SRKNLCLHPE VSKERKGTVV DEKCRRMTNG QAKRKLEEDP EANVELCEYH E NLYNIEVE ...文字列:
MKFYIDDLPV LFPYPKIYPE QYNYMCDIKK TLDVGGNSIL EMPSGTGKTV SLLSLTIAYQ MHYPEHRKII YCSRTMSEIE KALVELENL MDYRTKELGY QEDFRGLGLT SRKNLCLHPE VSKERKGTVV DEKCRRMTNG QAKRKLEEDP EANVELCEYH E NLYNIEVE DYLPKGVFSF EKLLKYCEEK TLCPYFIVRR MISLCNIIIY SYHYLLDPKI AERVSNEVSK DSIVIFDEAH NI DNVCIES LSLDLTTDAL RRATRGANAL DERISEVRKV DSQKLQDEYE KLVQGL(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)RAEHFVSFL KRLIEYLKTR M KVLHVISE TPKSFLQHLK QLTFIERKPL RFCSERLSLL VRTLEVTEVE DFTALKDIAT FATLISTYEE GFLLIIEPYE IE NAAVPNP IMRFTCLDAS IAIKPVFERF SSVIITSGTI SPLDMYPRML NFKTVLQKSY AMTLAKKSFL PMIITKGSDQ VAI SSRFEI RNDPSIVRNY GSMLVEFAKI TPDGMVVFFP SYLYMESIVS MWQTMGILDE VWKHKLILVE TPDAQETSLA LETY RKACS NGRGAILLSV ARGKVSEGID FDHQYGRTVL MIGIPFQYTE SRILKARLEF MRENYRIREN DFLSFDAMRH AAQCL GRVL RGKDDYGVMV LADRRFSRKR SQLPKWIAQG LSDADLNLST DMAISNTKQF LRTMAQPTDP KDQEGVSVWS YEDLIK HQN SRKDQGGFIE NENKEGEQDE DEDEDIEMQ

UniProtKB: General transcription and DNA repair factor IIH helicase subunit XPD/RAD3, General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

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分子 #24: General transcription and DNA repair factor IIH subunit TFB1

分子名称: General transcription and DNA repair factor IIH subunit TFB1
タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 53.385336 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MSHSGAAIFE KVSGIIAINE DVSPAELTWR STDGDKVHTV VLSTIDKLQA TPASSEKMML RLIGKVDESK KRKDNEGNEV VPKPQRHMF SFNNRTVMDN IKMTLQQIIS RYKDADIYEE KR(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)TNLKLQQSL ...文字列:
MSHSGAAIFE KVSGIIAINE DVSPAELTWR STDGDKVHTV VLSTIDKLQA TPASSEKMML RLIGKVDESK KRKDNEGNEV VPKPQRHMF SFNNRTVMDN IKMTLQQIIS RYKDADIYEE KR(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)TNLKLQQSL LKGNKVLMKV FQETVINAGL PPSEFWSTRI PLLR(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)NLS REKILNIFEN YPIVKKAYTD NVPKNFKEPE FW ARFFSSK LFRK(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)SALGSFVDN T SQANELEV KSTLPIDLLE SCRMLHTTCC EFLKHFYIHF QSGEQKQAST VKKLYNHLKD CIEKLNELFQ DVLNGDGESM SN TCTAYLK PVLNSITLAT HKYDEYFNEY NNNSN

UniProtKB: General transcription and DNA repair factor IIH subunit TFB1, General transcription and DNA repair factor IIH subunit TFB1, General transcription and DNA repair factor IIH subunit TFB1, ...UniProtKB: General transcription and DNA repair factor IIH subunit TFB1, General transcription and DNA repair factor IIH subunit TFB1, General transcription and DNA repair factor IIH subunit TFB1, General transcription and DNA repair factor IIH subunit TFB1

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分子 #25: General transcription and DNA repair factor IIH subunit TFB2

分子名称: General transcription and DNA repair factor IIH subunit TFB2
タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 60.16893 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MSDYSLKHSV TQYLEEIPQQ VQNRLYTSPA TCLAIYRILP PLAKFFIMAM VFNENEVPLL DLDKWVNSNG KLQFQNAIKS MKSLHLLIP NKSSGTLMIN LNPTFKISLR NAL(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK) ...文字列:
MSDYSLKHSV TQYLEEIPQQ VQNRLYTSPA TCLAIYRILP PLAKFFIMAM VFNENEVPLL DLDKWVNSNG KLQFQNAIKS MKSLHLLIP NKSSGTLMIN LNPTFKISLR NAL(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)SEKVLNL LKHSKLMEEV NSTGEFKITN EGFQFLLQ(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) KMDLVDVLHF IFMLGALEVG KAYKIDALSE TQRIMLQDMR DYGLVFQKHS NDSIFYPTKL ALMLTSD(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) TKTIRSASNA MDSVLRQNRE EPSVNEDGAN GKSTTDITTS DDLNK AGLK NQDIPDGSLI VETNFKIYSY SNSPLQIAVL SLFVHLKARF VNMVLGQITR ESIRRALTNG ITADQIIAYL ETHAHP QMR RLAEEKLEKK LELDPNCKEP LQVLPPTVVD QIRLWQLELD RVITYEGSLY SDFETSQEYN LLSKYAQDIG VLLWKDD KK KKFFISKEGN SQVLDFAKRK LKKKQ

UniProtKB: General transcription and DNA repair factor IIH subunit TFB2, General transcription and DNA repair factor IIH subunit TFB2, General transcription and DNA repair factor IIH subunit TFB2, ...UniProtKB: General transcription and DNA repair factor IIH subunit TFB2, General transcription and DNA repair factor IIH subunit TFB2, General transcription and DNA repair factor IIH subunit TFB2, General transcription and DNA repair factor IIH subunit TFB2

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分子 #26: RNA polymerase II transcription factor B subunit 3

分子名称: RNA polymerase II transcription factor B subunit 3 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 38.188438 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MLMDEYEENK DMCPICKTDR YLSPDVKFLV NPECYHRICE SCVDRIFSLG PAQCPYKGCD KILRKNKFKT QIFDDVEVEK EVDIRKRVF NVFNKTIDDF NGDLVEYNKY LEEVEDIIYK LDHGIDVAKT EEKLRTYEEL NKQLIMNNLE RSRTEIESFE Q RQKFEKEM ...文字列:
MLMDEYEENK DMCPICKTDR YLSPDVKFLV NPECYHRICE SCVDRIFSLG PAQCPYKGCD KILRKNKFKT QIFDDVEVEK EVDIRKRVF NVFNKTIDDF NGDLVEYNKY LEEVEDIIYK LDHGIDVAKT EEKLRTYEEL NKQLIMNNLE RSRTEIESFE Q RQKFEKEM KLKKRLLERQ IEEEERMNKE WTKKEIVNRL STTTQDINET IEGVKNTVKL KKSSARRKLE ELNRVLKNNP YF NSNVNVQ NSRLKDAVPF TPFNGDREAH PRFTLKGSVY NDPFIKDLEH RKEFIASGFN TNYAYERVLT EAFMGLGCVI SEE L

UniProtKB: RNA polymerase II transcription factor B subunit 3

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分子 #27: General transcription and DNA repair factor IIH subunit TFB4

分子名称: General transcription and DNA repair factor IIH subunit TFB4
タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 35.978059 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MDAISDPTFK HARSRKQVTE ESPSLLTVII EIAPKLWTTF DEEGNEKGSI IKVLEALIVF LNAHLAFNSA NKVAVIAAYS QGIKYLYP(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK) ...文字列:
MDAISDPTFK HARSRKQVTE ESPSLLTVII EIAPKLWTTF DEEGNEKGSI IKVLEALIVF LNAHLAFNSA NKVAVIAAYS QGIKYLYP(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)YRRFRNVDE TLVEEIYKLF ELEKKQIEQN SQRSTLAGAM SAGLTY VNR ISKESVTTSL KSRLLVLTCG SGSSKDEIFQ YIPIMNCIFS ATKMKCPIDV VKIGGSKEST FLQQTTDATN GVYLHVE ST EGLIQYLATA MFIDP(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)TSCYLTG RVVAVGFICS VCLCVLSIIP PGNKCPACDS QFDEHVIAKL KRKPVVPR L KAKKKVTKP

UniProtKB: General transcription and DNA repair factor IIH subunit TFB4, General transcription and DNA repair factor IIH subunit TFB4, General transcription and DNA repair factor IIH subunit TFB4

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分子 #28: General transcription and DNA repair factor IIH subunit TFB5

分子名称: General transcription and DNA repair factor IIH subunit TFB5
タイプ: protein_or_peptide / ID: 28 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 8.24349 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列:
MARARKGALV QCDPSIKALI LQIDAKMSDI VLEELDDTHL LVNPSKVEFV KHELNRLLSK NIYNPMDEEE NQ

UniProtKB: General transcription and DNA repair factor IIH subunit TFB5

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分子 #29: General transcription and DNA repair factor IIH subunit SSL1

分子名称: General transcription and DNA repair factor IIH subunit SSL1
タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 51.122695 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MAPVVISESE EDEDRVAITR RTKRQVHFDG EGDDRVDQQQ QQHSSSHRDR DKHVQRKKKK RLSNRNLQGS NGGYAWEDEI KRSWDLVKV DDEGDMASLV ASIVEARKKR TAKKNITPYQ RGIIRSLILT LDCSEAMLEK DLRPNRHAMI IQYAIDFVHE F FDQNPISQ ...文字列:
MAPVVISESE EDEDRVAITR RTKRQVHFDG EGDDRVDQQQ QQHSSSHRDR DKHVQRKKKK RLSNRNLQGS NGGYAWEDEI KRSWDLVKV DDEGDMASLV ASIVEARKKR TAKKNITPYQ RGIIRSLILT LDCSEAMLEK DLRPNRHAMI IQYAIDFVHE F FDQNPISQ MGIIIMRNGL AQLVSQVSGN PQDHIDALKS IRKQEPKGNP SLQNALEMAR GLLLPVPAHC TREVLIVFGS LS TTDPGDI HQTIDSLVSE KIRVKVLGLS AQVAICKELC KATNYGDESF YKILLDETHL KELFNEAVTP (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)PT RIF EDTPTF CSCHSKLVYG GYFCPNCHSK VCSLPTVCPC CDLMLIL(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)KTFAEVPT TEKFRSEDCF SCQSRFP(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)SRYRCEDCK QEFCVDCDVF IHEILHNCPG CESKPV IT

UniProtKB: General transcription and DNA repair factor IIH subunit SSL1, General transcription and DNA repair factor IIH subunit SSL1, General transcription and DNA repair factor IIH subunit SSL1, ...UniProtKB: General transcription and DNA repair factor IIH subunit SSL1, General transcription and DNA repair factor IIH subunit SSL1, General transcription and DNA repair factor IIH subunit SSL1, General transcription and DNA repair factor IIH subunit SSL1

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分子 #30: General transcription and DNA repair factor IIH helicase subunit XPB

分子名称: General transcription and DNA repair factor IIH helicase subunit XPB
タイプ: protein_or_peptide / ID: 30 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 94.049695 KDa
組換発現生物種: Trichoplusia ni (イラクサキンウワバ)
配列文字列: MTDVEGYQPK SKGKIFPDMG ESFFSSDEDS PATDAEIDEN YDDNRETSEG RGERDTGAMV TGLKKPRKKT KSSRHTAADS SMNQMDAKD KALLQDTNSD IPADFVPDSV SGMFRSHDFS YLRLRPDHAS RPLWISPSDG RIILESFSPL AEQAQDFLVT I AEPISRPS ...文字列:
MTDVEGYQPK SKGKIFPDMG ESFFSSDEDS PATDAEIDEN YDDNRETSEG RGERDTGAMV TGLKKPRKKT KSSRHTAADS SMNQMDAKD KALLQDTNSD IPADFVPDSV SGMFRSHDFS YLRLRPDHAS RPLWISPSDG RIILESFSPL AEQAQDFLVT I AEPISRPS HIHEYKITAY SLYAAVSVGL ETDDIISVLD RLSKVPVAES IINFIKGATI SYGKVKLVIK HNRYFVETTQ AD ILQMLLN DSVIGPLRID SDHQVQPPED VLQQQLQQTA GKPATNVNPN DVEAVFSAVI GGDNEREEED DDIDAVHSFE IAN ESVEVV KKRCQEIDYP VLEEYDFRND HRNPDLDIDL KPSTQIRPYQ EKSLSKMFGN GRARSGIIVL PCGAGKTLVG ITAA CTIKK SVIVLCTSSV SVMQWRQQFL (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)LVV ST YSMVAN(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)W GFIILDEVHV VPAAMFRRVV STIAAHAKLG LTATLVREDD KIGDLNFLIG PKLY EANWM ELSQKGHIAN VQCAEVWCPM TAEFYQEYLR ETARKRMLLY IMNPTKFQAC QFLIQYHERR GDKIIVFSDN VYALQ EYAL KMGKPFIYGS TPQQERMNIL QNFQYNDQIN TIFLSKVGDT SIDLPEATCL IQISSHYGSR RQEAQRLGRI LRAKRR NDE GFNAFFYSLV SKDTQEMYYS TKRQAFLVDQ GYAFKVITHL HGMENIPNLA YASPRERREL LQEVLLKNEE AAGIEVG DD ADNSVGRGSN GHKRFKSKAV RGEGSLSGLA GGEDMAYMEY STNKNKELKE HHPLIRKMYY KNLKK

UniProtKB: General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2, General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

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分子 #31: Unknown protein

分子名称: Unknown protein / タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
分子量理論値: 3.677524 KDa
配列文字列: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) ...文字列:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)

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分子 #32: Mediator of RNA polymerase II transcription subunit 6

分子名称: Mediator of RNA polymerase II transcription subunit 6
タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 32.844746 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MNVTPLDELQ WKSPEWIQVF GLRTENVLDY FAESPFFDKT SNNQVIKMQR QFSQLNDPNA AVNMTQNIMT LPDGKNGNLE EEFAYVDPA RRQILFKYPM YMQLEEELMK LDGTEYVLSS VREPDFWVIR KQRRTNNSGV GSAKGPEIIP LQDYYIIGAN I YQSPTIFK ...文字列:
MNVTPLDELQ WKSPEWIQVF GLRTENVLDY FAESPFFDKT SNNQVIKMQR QFSQLNDPNA AVNMTQNIMT LPDGKNGNLE EEFAYVDPA RRQILFKYPM YMQLEEELMK LDGTEYVLSS VREPDFWVIR KQRRTNNSGV GSAKGPEIIP LQDYYIIGAN I YQSPTIFK IVQSRLMSTS YHLNSTLESL YDLIEFQPSQ GVHYKVPTDT STTATAATNG NNAGGGSNKS SVRPTGGANM AT VPSTTNV NMTVNTMGTG GQTIDNGTGR TGNGNMGITT EMLDKLMVTS IRSTPNYI

UniProtKB: Mediator of RNA polymerase II transcription subunit 6

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分子 #33: Mediator of RNA polymerase II transcription subunit 8

分子名称: Mediator of RNA polymerase II transcription subunit 8
タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 25.297234 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSQSTASLVP EGNQGSLQED VSFDFNGVPG QALDAVRMRL AQLTHSLRRI RDEMSKAELP QWYTLQSQLN VTLSQLVSVT STLQHFQET LDSTVVYPLP KFPTTSHESL VTTLLRKKNI PEVDEWMKYV RETSGVTTAL LKDEEIEKLL QQDREITNWA R TTFRNEYG ...文字列:
MSQSTASLVP EGNQGSLQED VSFDFNGVPG QALDAVRMRL AQLTHSLRRI RDEMSKAELP QWYTLQSQLN VTLSQLVSVT STLQHFQET LDSTVVYPLP KFPTTSHESL VTTLLRKKNI PEVDEWMKYV RETSGVTTAL LKDEEIEKLL QQDREITNWA R TTFRNEYG KHDFKNEESL SEEHASLLVR DSKPSKPFNV DDVLKFTFTG EKPIITGSTS TSSSN

UniProtKB: Mediator of RNA polymerase II transcription subunit 8

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分子 #34: Mediator of RNA polymerase II transcription subunit 11

分子名称: Mediator of RNA polymerase II transcription subunit 11
タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 13.324189 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MQPPYIQERL KSLNDIETQL CSMLQEASQV TFIFGELKRG NESVKPQFEN HVKQFYERLD KSTTQLRKEI QLLDENVGTR LLPINVNKK ALGQDTEKME EQLDLLSAIL DPSKSK

UniProtKB: Mediator of RNA polymerase II transcription subunit 11

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分子 #35: Mediator of RNA polymerase II transcription subunit 17

分子名称: Mediator of RNA polymerase II transcription subunit 17
タイプ: protein_or_peptide / ID: 35 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 78.582836 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MTTEDPDSNH LSSETGIKLA LDPNLITLAL SSNPNSSLHS PTSDEPVPES AGKADTSIRL EGDELENKTK KDNDKNLKFL KNKDSLVSN PHEIYGSMPL EQLIPIILRQ RGPGFKFVDL NEKELQNEIK QLGSDSSDGH NSEKKDTDGA DENVQIGEDF M EVDYEDKD ...文字列:
MTTEDPDSNH LSSETGIKLA LDPNLITLAL SSNPNSSLHS PTSDEPVPES AGKADTSIRL EGDELENKTK KDNDKNLKFL KNKDSLVSN PHEIYGSMPL EQLIPIILRQ RGPGFKFVDL NEKELQNEIK QLGSDSSDGH NSEKKDTDGA DENVQIGEDF M EVDYEDKD NPVDSRNETD HKTNENGETD DNIETVMTQE QFVKRRRDML EHINLAMNES SLALEFVSLL LSSVKESTGM SS MSPFLRK VVKPSSLNSD KIPYVAPTKK EYIELDILNK GWKLQSLNES KDLLRASFNK LSSILQNEHD YWNKIMQSIS NKD VIFKIR DRTSGQKLLA IKYGYEDSGS TYKHDRGIAN IRNNIESQNL DLIPHSSSVF KGTDFVHSVK KFLRVRIFTK IESE DDYIL SGESVMDRDS ESEEAETKDI RKQIQLLKKI IFEKELMYQI KKECALLISY GVSIENENKV IIELPNEKFE IELLS LDDD SIVNHEQDLP KINDKRANLM LVMLRLLLVV IFKKTLRSRI SSPHGLINLN VDDDILIIRP ILGKVRFANY KLLLKK IIK DYVLDIVPGS SITETEVERE QPQENKNIDD ENITKLNKEI RAFDKLLNIP RRELKINLPL TEHKSPNLSL MLESPNY CN ALIHIKFSAG TEANAVSFDT TFSDFKEVED FLHFIVAEYI QQKKV

UniProtKB: Mediator of RNA polymerase II transcription subunit 17

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分子 #36: Mediator of RNA polymerase II transcription subunit 18

分子名称: Mediator of RNA polymerase II transcription subunit 18
タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 34.316539 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MVQQLSLFGS IGDDGYDLLI STLTTISGNP PLLYNSLCTV WKPNPSYDVE NVNSRNQLVE PNRIKLSKEV PFSYLIDETM MDKPLNFRI LKSFTNDKIP LNYAMTRNIL HNTVPQVTNF NSTNEDQNNS KHTEDTVNES RNSDDIIDVD MDASPAPSNE S CSPWSLQI ...文字列:
MVQQLSLFGS IGDDGYDLLI STLTTISGNP PLLYNSLCTV WKPNPSYDVE NVNSRNQLVE PNRIKLSKEV PFSYLIDETM MDKPLNFRI LKSFTNDKIP LNYAMTRNIL HNTVPQVTNF NSTNEDQNNS KHTEDTVNES RNSDDIIDVD MDASPAPSNE S CSPWSLQI SDIPAAGNNR SVSMQTIAET IILSSAGKNS SVSSLMNGLG YVFEFQYLTI GVKFFMKHGL ILELQKIWQI EE AGNSQIT SGGFLLKAYI NVSRGTDIDR INYTETALMN LKKELQGYIE LSVPDRQSMD SRVAHGNILI

UniProtKB: Mediator of RNA polymerase II transcription subunit 18

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分子 #37: Mediator of RNA polymerase II transcription subunit 20

分子名称: Mediator of RNA polymerase II transcription subunit 20
タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 22.918068 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MGKSAVIFVE RATPATLTEL KDALSNSILS VRDPWSIDFR TYRCSIKNLP ADVSKLMYSI TFHHHGRQTV LIKDNSAMVT TAAAADIPP ALVFNGSSTG VPESIDTILS SKLSNIWMQR QLIKGDAGET LILDGLTVRL VNLFSSTGFK GLLIELQADE A GEFETKIA ...文字列:
MGKSAVIFVE RATPATLTEL KDALSNSILS VRDPWSIDFR TYRCSIKNLP ADVSKLMYSI TFHHHGRQTV LIKDNSAMVT TAAAADIPP ALVFNGSSTG VPESIDTILS SKLSNIWMQR QLIKGDAGET LILDGLTVRL VNLFSSTGFK GLLIELQADE A GEFETKIA GIEGHLAEIR AKEYKTSSDS LGPDTSNEIC DLAYQYVRAL EL

UniProtKB: Mediator of RNA polymerase II transcription subunit 20

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分子 #38: Mediator of RNA polymerase II transcription subunit 22

分子名称: Mediator of RNA polymerase II transcription subunit 22
タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 13.875731 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MSNQALYEKL EQTRTILSVK LAELINMTTI ADRNDDDEGS FAQENSELAV ATTSVMMVNN QTMQLIKNVQ DLLILTRSIK EKWLLNQIP VTEHSKVTRF DEKQIEELLD NCIETFVAEK TT

UniProtKB: Mediator of RNA polymerase II transcription subunit 22

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分子 #39: Mediator of RNA polymerase II transcription subunit 4

分子名称: Mediator of RNA polymerase II transcription subunit 4
タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 33.606543 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSVQDTKAVE FSMGHIRSSS VSLVAEATSN TNSEDKLSKV QLYEDLCRYE DTLSKLVESV DRFKPNLDIA KDLIRTDEAL FENVKLLAE YDNIYRNLQK IDKDSEELDS KTRKILEILN ECHDEL(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK) ...文字列:
MSVQDTKAVE FSMGHIRSSS VSLVAEATSN TNSEDKLSKV QLYEDLCRYE DTLSKLVESV DRFKPNLDIA KDLIRTDEAL FENVKLLAE YDNIYRNLQK IDKDSEELDS KTRKILEILN ECHDEL(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)KALPMLE QVEFEKNTIL QQRSKINSTE LLDYATKL S KFTKIPPTFD KGAVGPNNFI WPAEDALRRG MLAMASLHSK ELTRIPGEEV EETEVPTVPP SQSEEQKGQM AKKEGTPKT DSFIFDGTAK EVGDEADNTK DKEKEENNDD ALDLDLDLFD PDDF

UniProtKB: Mediator of RNA polymerase II transcription subunit 4, Mediator of RNA polymerase II transcription subunit 4

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分子 #40: Mediator of RNA polymerase II transcription subunit 7

分子名称: Mediator of RNA polymerase II transcription subunit 7
タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 25.687055 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSNDPGNEVS SLYSPTSPSY VKFFTQSNLE KLPKYKEKKA ASAKQTAPNN SNGGSEEEIT CALDYLIPPP MPKNQQYRAF GSIWQVKDQ LPDLESMGLT QLYKKSTENE STNYQYKIQE LRKLLKSLLL NYLELIGVLS INPDMYERKV ENIRTILVNI H HLLNEYRP ...文字列:
MSNDPGNEVS SLYSPTSPSY VKFFTQSNLE KLPKYKEKKA ASAKQTAPNN SNGGSEEEIT CALDYLIPPP MPKNQQYRAF GSIWQVKDQ LPDLESMGLT QLYKKSTENE STNYQYKIQE LRKLLKSLLL NYLELIGVLS INPDMYERKV ENIRTILVNI H HLLNEYRP HQSRESLIML LEEQLEYKRG EIREIEQVCK QVHDKLTSIQ DTLRTGSQSP PSSSQ

UniProtKB: Mediator of RNA polymerase II transcription subunit 7

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分子 #41: Mediator of RNA polymerase II transcription subunit 9

分子名称: Mediator of RNA polymerase II transcription subunit 9
タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 17.400377 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MNLQNNVLNQ IHQILLPTNP TLDKPNAEAT KEEFSSAENR DEKDYLTNQQ PKNLSTPSTS SNGEFIPHIF YSLHQIRKDP NNLSNQLET LTGSIRHRLK LCKSLISENE DTKDLLSKSP SEWQDIIHQR EQELQIKRDV LDDLYRKLQR

UniProtKB: Mediator of RNA polymerase II transcription subunit 9

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分子 #42: Mediator of RNA polymerase II transcription subunit 10

分子名称: Mediator of RNA polymerase II transcription subunit 10
タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 17.927926 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MNGNSTNNEQ LQQELATTQD QVASIIESFV ELGVSIYDFP GTPEATKGMI TNLQRNVDRL YKLNVRSNDP QSSLSKVDIP LEVVQYIED GRNPDIYTRE FVEAIRRSNQ YQRGKMHGLK QLRDSLADKI VDEFPELKEP VEDIIKRTSP IDNVSNTH

UniProtKB: Mediator of RNA polymerase II transcription subunit 10

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分子 #43: Mediator of RNA polymerase II transcription subunit 14

分子名称: Mediator of RNA polymerase II transcription subunit 14
タイプ: protein_or_peptide / ID: 43 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 84.746539 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MTTTIGSPQM LANEERLSNE MHALKNRSEQ NGQEQQGPVK NTQLHGPSAT DPETTATQKE SLEMVPKDTS AATMTSAPPP ALPHVEINQ VSLALVIRNL TVFTMKELAQ YMKTNVHTQA NEPNSAKKIR FLQLIIFLRT QFLKLYVLVK WTRTIKQNNF H VLIDLLNW ...文字列:
MTTTIGSPQM LANEERLSNE MHALKNRSEQ NGQEQQGPVK NTQLHGPSAT DPETTATQKE SLEMVPKDTS AATMTSAPPP ALPHVEINQ VSLALVIRNL TVFTMKELAQ YMKTNVHTQA NEPNSAKKIR FLQLIIFLRT QFLKLYVLVK WTRTIKQNNF H VLIDLLNW FRTTNMNVNN CIWALKSSLN SMTNAKLPNV DLVTALEVLS LGRPNLPTHN FKLSGVSNSM DMVDGMAKVP IG LILQRLK DLNLTVSIKI ALMNIPKPLN SYHIKNGRIY FTVPNEFEIQ LSTVNRQSPL FFVDLKLLFN TEAEQTVSAV TEA TSTNGD SENNEENSSS NGNNLPLNKP RLEKLINEIL LKSNDPLLSL YNFLHKYVLT LQLYMVHREF LKLANGGKFS KSNL IHNYD SKKSTITVRY WLNGKMDSKG KITIGIQRTT ESLILKWDNQ SASRAKNMPV IYNNIVSNIE GILDEIMFNH ARIIR SELL ARDIFQEDEE NSDVLLFQLP TTCVSMAPIQ LKIDLLSGQF YFRNPTPLLS NYASKINRAE GPEELARILQ QLKLDK IIH VLTTMFENTG WSCSRIIKID KPIRTQVNTG GESVVKKEDN KYAIAGNSTT NSDVSLLLQR DLFIRLPHWP LNWYLIL SI ISSKTSCVVE KRIGKIVSQR GKWNLKYLDN SNVMTVKLES ITYQKIMILQ RTILNRIINH MLIDSLNQLE IRNKICSS E MINEQKLPQY IIQGSNTNDN ISII

UniProtKB: Mediator of RNA polymerase II transcription subunit 14

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分子 #44: Mediator of RNA polymerase II transcription subunit 19

分子名称: Mediator of RNA polymerase II transcription subunit 19
タイプ: protein_or_peptide / ID: 44 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 24.885305 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MASRVDETTV PSYYYYVDPE TTYTYQQPNP LQDLISVYGL DDISRQVART NLDGTKAVKL RKSYKNQIAD LSGKFSTIPT RENGKGGQI AHILFQNNPD MMIQPPQQGQ NMSEQQWREQ LRNRDIALFQ PPNFDWDLCS SVLSQFERSY PSEFANQNQG G AQAPFDID ...文字列:
MASRVDETTV PSYYYYVDPE TTYTYQQPNP LQDLISVYGL DDISRQVART NLDGTKAVKL RKSYKNQIAD LSGKFSTIPT RENGKGGQI AHILFQNNPD MMIQPPQQGQ NMSEQQWREQ LRNRDIALFQ PPNFDWDLCS SVLSQFERSY PSEFANQNQG G AQAPFDID DLAFDLDGTG KSQSGSNSGN NSKKRKNKSS GSSMATPTHS DSHEDMKRRR LE

UniProtKB: Mediator of RNA polymerase II transcription subunit 19

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分子 #45: Mediator of RNA polymerase II transcription subunit 21

分子名称: Mediator of RNA polymerase II transcription subunit 21
タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 16.093368 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列:
MTDRLTQLQI CLDQMTEQFC ATLNYIDKNH GFERLTVNEP QMSDKHATVV PPEEFSNTID ELSTDIILKT RQINKLIDSL PGVDVSAEE QLRKIDMLQK KLVEVEDEKI EAIKKKEKLL RHVDSLIEDF VDGIANSKKS T

UniProtKB: Mediator of RNA polymerase II transcription subunit 21

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分子 #46: Mediator of RNA polymerase II transcription subunit 31,Mediator o...

分子名称: Mediator of RNA polymerase II transcription subunit 31,Mediator of RNA polymerase II transcription subunit 31
タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
分子量理論値: 16.790234 KDa
組換発現生物種: Escherichia coli BL21(DE3) (大腸菌)
配列文字列: MSSTNGNAPA TPSSDQNPLP TRFEVELEFI QSLANIQYVT YLLTQQQIWK SPNFKNYLKY LEYWCNPPYS QCIVYPNCLF ILKLLNGFM ESAIVNEDGL LEGLDELPKI IQLQGPQWMN EMVERWAN(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) ...文字列:
MSSTNGNAPA TPSSDQNPLP TRFEVELEFI QSLANIQYVT YLLTQQQIWK SPNFKNYLKY LEYWCNPPYS QCIVYPNCLF ILKLLNGFM ESAIVNEDGL LEGLDELPKI IQLQGPQWMN EMVERWAN(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)

UniProtKB: Mediator of RNA polymerase II transcription subunit 31

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分子 #14: NONTEMPLATE DNA

分子名称: NONTEMPLATE DNA / タイプ: dna / ID: 14 / コピー数: 1 / 分類: DNA
由来(天然)生物種: synthetic construct (人工物)
分子量理論値: 32.716977 KDa
配列文字列: (DC)(DG)(DA)(DG)(DA)(DA)(DC)(DA)(DG)(DT) (DA)(DG)(DC)(DA)(DC)(DG)(DC)(DT)(DG)(DT) (DG)(DT)(DA)(DT)(DA)(DT)(DA)(DA)(DT) (DA)(DG)(DC)(DT)(DA)(DT)(DG)(DG)(DA)(DA) (DC) (DG)(DT)(DT)(DC)(DG) ...文字列:
(DC)(DG)(DA)(DG)(DA)(DA)(DC)(DA)(DG)(DT) (DA)(DG)(DC)(DA)(DC)(DG)(DC)(DT)(DG)(DT) (DG)(DT)(DA)(DT)(DA)(DT)(DA)(DA)(DT) (DA)(DG)(DC)(DT)(DA)(DT)(DG)(DG)(DA)(DA) (DC) (DG)(DT)(DT)(DC)(DG)(DA)(DT)(DT) (DC)(DA)(DC)(DC)(DT)(DC)(DC)(DG)(DA)(DT) (DG)(DT) (DG)(DT)(DG)(DT)(DT)(DG)(DT) (DA)(DC)(DA)(DT)(DA)(DC)(DA)(DT)(DA)(DA) (DA)(DA)(DA) (DT)(DA)(DT)(DC)(DA)(DT) (DA)(DG)(DC)(DA)(DC)(DA)(DA)(DC)(DT)(DG) (DC)(DG)(DC)(DT) (DG)(DT)(DG)(DT)(DC) (DA)

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分子 #18: TEMPLATE DNA

分子名称: TEMPLATE DNA / タイプ: dna / ID: 18 / コピー数: 1 / 分類: DNA
由来(天然)生物種: synthetic construct (人工物)
分子量理論値: 32.68092 KDa
配列文字列: (DT)(DG)(DA)(DC)(DA)(DC)(DA)(DG)(DC)(DG) (DC)(DA)(DG)(DT)(DT)(DG)(DT)(DG)(DC)(DT) (DA)(DT)(DG)(DA)(DT)(DA)(DT)(DT)(DT) (DT)(DT)(DA)(DT)(DG)(DT)(DA)(DT)(DG)(DT) (DA) (DC)(DA)(DA)(DC)(DA) ...文字列:
(DT)(DG)(DA)(DC)(DA)(DC)(DA)(DG)(DC)(DG) (DC)(DA)(DG)(DT)(DT)(DG)(DT)(DG)(DC)(DT) (DA)(DT)(DG)(DA)(DT)(DA)(DT)(DT)(DT) (DT)(DT)(DA)(DT)(DG)(DT)(DA)(DT)(DG)(DT) (DA) (DC)(DA)(DA)(DC)(DA)(DC)(DA)(DC) (DA)(DT)(DC)(DG)(DG)(DA)(DG)(DG)(DT)(DG) (DA)(DA) (DT)(DC)(DG)(DA)(DA)(DC)(DG) (DT)(DT)(DC)(DC)(DA)(DT)(DA)(DG)(DC)(DT) (DA)(DT)(DT) (DA)(DT)(DA)(DT)(DA)(DC) (DA)(DC)(DA)(DG)(DC)(DG)(DT)(DG)(DC)(DT) (DA)(DC)(DT)(DG) (DT)(DT)(DC)(DT)(DC) (DG)

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分子 #47: ZINC ION

分子名称: ZINC ION / タイプ: ligand / ID: 47 / コピー数: 16 / 式: ZN
分子量理論値: 65.409 Da

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分子 #48: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 48 / コピー数: 1 / 式: MG
分子量理論値: 24.305 Da

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分子 #49: IRON/SULFUR CLUSTER

分子名称: IRON/SULFUR CLUSTER / タイプ: ligand / ID: 49 / コピー数: 1 / 式: SF4
分子量理論値: 351.64 Da
Chemical component information

ChemComp-FS1:
IRON/SULFUR CLUSTER / 一硫化鉄

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態particle

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試料調製

濃度0.70 mg/mL
緩衝液pH: 7.6
グリッドモデル: Quantifoil R1.2/1.3 / 材質: GOLD / 前処理 - タイプ: GLOW DISCHARGE
詳細: QUANTIFOIL HOLEY GOLD GRIDS WERE GLOW-DISCHARGED BEFORE DEPOSITION OF SAMPLE.
凍結凍結剤: ETHANE / 装置: FEI VITROBOT MARK IV
詳細: Grids were blotted for 8 s and plunge-frozen in liquid ethane..

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: GATAN K2 SUMMIT (4k x 4k)
検出モード: COUNTING / 撮影したグリッド数: 3 / 実像数: 13000 / 平均露光時間: 10.0 sec. / 平均電子線量: 42.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / Cs: 2.7 mm / 最大 デフォーカス（公称値）: 5.0 µm / 最小 デフォーカス（公称値）: 0.5 µm / 倍率（公称値）: 105000
試料ステージ試料ホルダーモデル: FEI TITAN KRIOS AUTOGRID HOLDER
ホルダー冷却材: NITROGEN
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: EMDB MAP
最終 再構成想定した対称性 - 点群: C1 (非対称) / 解像度のタイプ: BY AUTHOR / 解像度: 5.8 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 16000
初期 角度割当タイプ: PROJECTION MATCHING / ソフトウェア - 名称: RELION (ver. 2.0.4)
最終 角度割当タイプ: PROJECTION MATCHING / ソフトウェア - 名称: RELION (ver. 2.0.4)

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原子モデル構築 1

精密化空間: REAL / プロトコル: OTHER
得られたモデル

PDB-5oqm:
STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る