Type Cyclic depsipeptide / Antibiotic Details THE ECHINOMYCIN IS A BICYCLIC OCTADEPSIPEPTIDE, A MEMBER OF THE QUINOXALINE CLASS OF ANTIBIOTICS. HERE, ECHINOMYCIN IS REPRESENTED BY GROUPING TOGETHER THE SEQUENCE (SEQRES) AND TWO LIGANDS (HET) QUI. ECHINOMYCIN IS A BICYCLIC OCTADEPSIPEPTIDE. BICYCLIZATION IS ACHIEVED BY LINKING THE N- AND THE C- TERMINI, AND A THIOACETAL BOND BETWEEN RESIDUES 3 AND 7. THE TWO QUINOXALINE CHROMOPHORES ARE LINKED TO THE D-SERINE RESIDUES, RESIDUES 1 AND 5. Downloads Molecular definition / Chemical definition / Family definitionSynonyms 2-Quinoxalinecarboxmide, N,N'-[2,4,12,15,17,25-hexamethyl-11,24-bis(1-methylethyl)-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa -28-thia-2,5,12,15,18,25-hexaazabicyclo[12.12.3]nonacosan e-7,20-diyl]bis- (ChemBank) Actinoleukin (BioAustralis) Antibiotic 1491 (BioAustralis) Antibiotic 59266 (BioAustralis) Antibiotic A 654I (SciFinder) Antibiotic C638-8 (ChemSpider) Antibiotic X 53III (BioAustralis) Antibiotic X 948 (BioAustralis) Crystalline Antibiotic C 638-8 (ChemSpider) ECHINOMYCIN (PDB) Echinomycin A (ChemSpider) Levomycin (Beilstein, ChemSpider) N,N'-(2,4,12,15,17,25-hexamethyl-11,24-bis(1-methylethyl)-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-thia-2,5,12,15,18,25-hexaazabicyclo(12.12.3)nonacosane-7,20-diyl)bis(2-quinoxalinecarboxamide) (ChemBank) N-[3,11,13,16,24,26-hexamethyl-27-methylsulfanyl-2,5,9,12,15,18,22,25-octaoxo-4,17-di(propan-2-yl)-8-(quinoxaline-2-carbonylamino)-6,19-dioxa-28-thia-3,10,13,16,23,26-hexazabicyclo[12.12.3]nonacosan-21-yl]quinoxaline-2-carboxamide (ChemBank) Quinomycin A (Merck, Beilstein, KEGG, PubChem, BioAustralis) Quinomycin A (9CI) (ChemSpider) S-426-S (lepetit) (ChemBank) SK 302B (ChemSpider, ChemBank) echinomycin A (ChemBank) levomycin (ChemBank) quinomycin A (ChemBank) Show more 17 items Show lessAnnotation Function : Antitumor / Info source : NovelAntibioticsFunction : Binds to DNA / Info source : PubChemFunction : inhibitor of RNA synthesis / Info source : PubChemSource External info Family quinoxaline TRIOSTIN A / Echinomycin / uk63052
Related structures Triostin A isoamyl acetate solvate, seqres C5 ALA-CYS*!,CYS*!-VAL*,SER*- C5 CYS*!-VAL*,SER*-ALA-CYS*!, / CCDC: CULVUA / PubMed / Reference Triostin A isoamyl acetate solvate, seqres C5 ALA-CYS*!,CYS*!-VAL*,SER*- C5 CYS*!-VAL*,SER*-ALA-CYS*!, / CCDC: CULVUA10 / Reference Triostin C chloroform solvate hydrate, seqres C5 ALA-CYS*!,CYS*!-LEU*,SER*- C5 CYS*!-LEU*,SER*-ALA-CYS*!, / CCDC: ZILGOQ / Reference Triostin A hydrochloride dimethylformamide solvate, seqres C5 ALA-CYS*!,CYS*!-VAL*,SER*- C5 CYS*!-VAL*,SER*-ALA-CYS*!, / CCDC: ZILHAD / Reference Des-N-tetramethyltriostin A dodecahydrate, Tandem dodecahydrate / CCDC: TANDEM30 / PubMed / Reference Des-N-tetramethyltriostin A tetradecahydrate / CCDC: BICKON / PubMed / Reference des-N-Tetramethyl-triostin A dodecahydrate / CCDC: TANDEM20 / PubMed / Reference Echinomycin bis(quinoline) acetone solvate hydrate, Echinomycin 2QN, seqres C5 ALA-CYS*!,CYS*!-VAL*,SER*- C5 CYS*!-VAL*,SER*-ALA-CYS*!, / CCDC: ZILGIK / Reference Des-N-tetramethyl-triostin A dodecahydrate / CCDC: TANDEM / Reference Des-N-tetramethyl-triostin A methanol solvate hydrate / CCDC: TMTRST / Reference Show more 6 items Show less