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-List of structure papers
Showing 1 - 20 of 125,656 items (all data)
-Thermodynamic Insights into the WT and Y220C TP53 DBDs Reveals that the Oncogenic Y220C Variant is a Loss of Function Mutation for Zn2+-binding at Physiological Temperature
To Be Published,
Stuckey, J.I. / Vivat, V. / Dickson, B.M. / Setser, J.W. / Li, Y. / Cremers, C.M. / Wilson, J.E. / Peterle, D. / Engen, J.R. / Wales, T.E. ...Stuckey, J.I. / Vivat, V. / Dickson, B.M. / Setser, J.W. / Li, Y. / Cremers, C.M. / Wilson, J.E. / Peterle, D. / Engen, J.R. / Wales, T.E. / Wilcken, R. / Rohan, E.B. / Chenail, G. / Audia, J.E. / Sims, R.J.
Methods: X-ray diffraction
-Crystal Structure of the beta-Glucosidase BglA9 in Complex with the Inhibitor Conduritol B Epoxide
To Be Published,
Rahman, U.U. / Sagmeister, T. / Grininger, C. / Gruber, K. / Khan, S.
Methods: X-ray diffraction
-Cryo-EM Structure of GTP Cyclohydrolase I from Candida albicans bound to 8-oxo GTP at 1.74 A
To Be Published,
Oluwarotimi EA / Guo Y / Vago F / Klose T / Borek D / Mesecar AD / Center for Structural Biology of Infectious Diseases (CSBID)
Methods: EM (single particle)
-Cryo-EM Structure of GTP Cyclohydrolase I from Candida albicans
To Be Published,
Oluwarotimi EA / Guo Y / Borek D / Mesecar AD / Center for Structural Biology of Infectious Diseases (CSBID)
Methods: EM (single particle)
-Systematic De-Risking of TCR-Mimic Therapeutics Through Proteome-Wide Off-Target Landscaping and a Generalizable Design Rule Framework
To Be Published,
Schuster S / Hartl FA / Stehle J / Beier F / Al-Hasani H / Reinhart C / Weng T-H / Kraemer S / Hamde P / Herz T ...Schuster S / Hartl FA / Stehle J / Beier F / Al-Hasani H / Reinhart C / Weng T-H / Kraemer S / Hamde P / Herz T / Oesterlin S / Schmidt M / Gross T / Stehl L / Kilb N / Juenemann G / Heiss K / Sinclair A / Schoettgen J / Meyer P / Atay B / Zaghla BKQ / Link S / Goll J / Leoni B / Steinmann B / Selinger O / Welsch S / Roth G / Michel H / Klatt M / Birkenfeld J
Methods: EM (single particle)
-Virome-wide ubiquitin ligase discovery reveals diverse mechanisms of immune evasion.
Science, Vol. 393, Issue 6813, Page eaec6299, Year 2026
Caleb R Glassman / Kheewoong Baek / Gaopeng Hou / Qiru Zeng / Christopher Nardone / Kate B Juergens / Eric Fujimura / Colin N O'Leary / Mamie Z Li / Joao A Paulo ...Caleb R Glassman / Kheewoong Baek / Gaopeng Hou / Qiru Zeng / Christopher Nardone / Kate B Juergens / Eric Fujimura / Colin N O'Leary / Mamie Z Li / Joao A Paulo / Eric S Fischer / Siyuan Ding / J Wade Harper / Stephen J Elledge
Methods: EM (single particle)
-Structure and biochemical analyses suggest that PrkA/YeaG protein of Thermus thermophilus functions as a putative molecular chaperone.
J Biochem, Vol. 180, Issue 3, Page 217-230, Year 2026
Masayuki Torii / Ryo Kanno / Akira Mizoguchi / Bruno M Humbel / Kazutoshi Tani / Ryoji Masui
Methods: EM (single particle)
-Protein Engineering-Enabled Cryo-EM Investigation of Small GTPases.
J Mol Biol, Vol. 438, Issue 17, Page 169860, Year 2026
Zhengshan Hu / Unnatiben Rajeshbhai Patel / Eliezra Glasser / Akiko Koide / Shohei Koide
Methods: EM (single particle)
-Equivalent gain-of-function variants in KCNK3 and KCNK9 and their contribution to distinct TASK K2P channelopathies.
J Gen Physiol, Vol. 158, Issue 5, Year 2026
Kate M Crowther / Thibault R H Jouen-Tachoire / Peter Proks / Peter Rory Hall / Emma L Veale / Janina Sörmann / Karin E J Rödström / Thomas Müller / Saskia B Wortmann / Nina Barisic ...Kate M Crowther / Thibault R H Jouen-Tachoire / Peter Proks / Peter Rory Hall / Emma L Veale / Janina Sörmann / Karin E J Rödström / Thomas Müller / Saskia B Wortmann / Nina Barisic / Natalie Hauser / Vincenzo Salpietro / RaeLynn Forsyth / Linford Williams / Nora Derrabi / Carlos A Bacino / Jill A Rosenfeld / Henry Houlden / Simon Newstead / Caroline F Wright / James Fasham / Alistair A Mathie / Reza Maroofian / Stephen J Tucker
Methods: EM (single particle)
-Structural Insights into Native, Mature Human Endogenous Retrovirus K (HERV-K) Capsids
To Be Published,
Lyu C / Peeples CA / Zhang Z / Shen Y / Hou Z / Harding EF / Hope J / Perilla JR / Katzourakis A / Zhang P
Methods: EM (subtomogram averaging) / EM (single particle)
-The in stiu structure of the mature capsid of bacteriophage A1002
-Programmed mineralization of metal-oxides by de novo designed protein templates
To Be Published,
Saragovi, A. / Pyles, H. / Bera, A.K. / Baker, D.
Methods: X-ray diffraction
-Histone modification crosstalk between host and pathogen
-In-cell structural analysis reveals a distinctive chloroplast ribosome in Chlamydomonas reinhardtii
To Be Published,
Hou Z / Shen Y / Zhang Z / Lu P / Katzourakis A / Zhang P
Methods: EM (subtomogram averaging)
-Predictive improvement of an RNA polymerase ribozyme from its substrate-free cryo-EM structure
To Be Published,
Szokoli D / Hingey J / Zhiheng Y / Wu V / Toor N / Spellmon N / Rudolfs B / Mencino A / Haack DB / Das R
Methods: EM (single particle)
-Structural mechanism governing the directionality of bridge recombination.
Nature, Year 2026
Masahiro Hiraizumi / Januka S Athukoralage / Nicholas T Perry / Eisuke Tsujimoto / Nami Shiojiri / Naoto Nagahata / Lauren Lee / Gwanggyu Sun / Matthew G Durrant / Sita S Chandrasekaran ...Masahiro Hiraizumi / Januka S Athukoralage / Nicholas T Perry / Eisuke Tsujimoto / Nami Shiojiri / Naoto Nagahata / Lauren Lee / Gwanggyu Sun / Matthew G Durrant / Sita S Chandrasekaran / Silvana Konermann / Keitaro Yamashita / Patrick D Hsu / Hiroshi Nishimasu
Methods: EM (single particle)
-Dual MYC and GSPT1 Protein Degrader for MYC-Driven Hematologic Malignancies.
Blood, Year 2026
Yuki Nishida / Valeria Impedovo / Edward Ayoub / Natalia Baran / Darah A Scruggs / Hideaki Mizuno / Shayaun Khazaei / Lauren B Ostermann / Kazuharu Kamachi / Liang Zhang ...Yuki Nishida / Valeria Impedovo / Edward Ayoub / Natalia Baran / Darah A Scruggs / Hideaki Mizuno / Shayaun Khazaei / Lauren B Ostermann / Kazuharu Kamachi / Liang Zhang / Jo Ishizawa / Sandeep Singh / Andrea D Bedoy / Po Yee Mak / Bing Z Carter / Eiji Sugihara / Tetsuya Takimoto / Youzhi Tong / Honghua Yan / Dong Chen / Ji Huang / Hsu-Feng Chu / Liang Tong / Zamal Ahmed / Sarita Namjoshi / John Tainer / Mihai Gagea / Thomas Huynh / Abhishek Maiti / Koji Sasaki / Branko Cuglievan / Steffen Boettcher / Torsten Haferlach / Stefano Tiziani / Liandong Ma / Michael Andreeff
Methods: EM (single particle)
-ARNT association reshapes ligand recognition by AHR PAS-B domain
-Decoding plant vacuolar phosphate efflux: Structural and dynamic insights from rice VPE2.
Proc Natl Acad Sci U S A, Vol. 123, Issue 33, Page e2611598123, Year 2026
Jiaqi Zuo / Shuo Cao / Ying Tang / Haitao He / Jie Zhang / Peiru Li / Yanke Chen / Ping Yin / Chuang Wang / Lizhong Xiong ...Jiaqi Zuo / Shuo Cao / Ying Tang / Haitao He / Jie Zhang / Peiru Li / Yanke Chen / Ping Yin / Chuang Wang / Lizhong Xiong / Faming Dong / Zhu Liu
Methods: EM (single particle)
-The structural basis for LRRK2's activation and autoinhibition.
Cell, Year 2026
Amalia Villagran Suarez / Kathryn S Hatch / Tatyana Bodrug / Wei Gai / Katherine J Surridge / Elizabeth Moussikhina / Kendrick H V Nguyen / Marta Sanz-Murillo / Robert Callahan / Erica Xiong ...Amalia Villagran Suarez / Kathryn S Hatch / Tatyana Bodrug / Wei Gai / Katherine J Surridge / Elizabeth Moussikhina / Kendrick H V Nguyen / Marta Sanz-Murillo / Robert Callahan / Erica Xiong / Delisa Ramos / Lawrence Zhu / Verena Dederer / Sebastian Mathea / Janet Iwasa / Stefan Knapp / Kevan M Shokat / Samara L Reck-Peterson / Andres E Leschziner
Methods: EM (single particle)
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