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Showing 1 - 50 of 96 items for (author: yelshanskaya & mv)

EMDB-47792: 
Structure of full length AMPA receptor GluA2 and auxiliary subunit TARP gamma-2 in complex with anti-miR 17 oligonucleotide RGLS4326
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-47793: 
Structure of AMPA receptor GluA2 and auxiliary subunit TARP gamma-2 (LBD-TMD) in complex with anti-miR 17 oligonucleotide RGLS4326
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-48888: 
Ligand-binding and transmembrane domains for GluK2-1xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48890: 
Ligand-binding and transmembrane domains for GluK2-2xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-49070: 
Consensus map for GluK2-2xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48889: 
Amino-terminal domain for GluK2-2xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48887: 
Amino-terminal domain for GluK2-1xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-49069: 
Consensus map for GluK2-1xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48897: 
Composite map for GluK2 in the apo state with asymmetric ligand binding domain
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48898: 
Composite map for GluK2 in the apo state with 2-fold symmetrical ligand-binding domain
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48899: 
Composite map for GluK2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48900: 
Composite map for GluK2-0xNeto2 in the apo state with asymmetric ligand-binding domain
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48901: 
Composite map for GluK2-1xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48902: 
Composite map for GluK2-2xNeto2 in the apo state
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48903: 
Composite map for GluK2-0xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48904: 
Composite map for GluK2-1xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-48905: 
Composite map for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Method: single particle / : Gangwar SP, Yelshanskaya MV, Yen LY, Newton TP, Sobolevsky AI

EMDB-47295: 
Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Philanthotoxin-74
Method: single particle / : Gangwar SP, Yen LY, Newton TP, Yelshanskaya MV, Sobolevsky AI

EMDB-47296: 
Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Nephilatoxin-8
Method: single particle / : Gangwar SP, Yen LY, Newton TP, Yelshanskaya MV, Sobolevsky AI

EMDB-47297: 
Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Spermine
Method: single particle / : Gangwar SP, Yen LY, Newton TP, Yelshanskaya MV, Sobolevsky AI

EMDB-47298: 
Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with positive allosteric modulator BPAM-344 and channel blocker Kukoamine-A
Method: single particle / : Yen LY, Newton TP, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-44123: 
Cryo-EM density of GluK2 amino-terminal domain (GluK2-ATD) from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44126: 
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44127: 
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44124: 
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44125: 
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44128: 
Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44129: 
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44130: 
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44131: 
Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-44132: 
Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI

EMDB-42994: 
Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-42995: 
Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-42996: 
Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-42997: 
Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-42998: 
Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI

EMDB-40741: 
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40742: 
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40743: 
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40744: 
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI

EMDB-40745: 
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40746: 
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40747: 
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40748: 
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40749: 
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-40750: 
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI

EMDB-16052: 
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
Method: single particle / : Absmeier E, Chandrasekaran V, O'Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA

EMDB-40676: 
Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV)
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI

EMDB-29343: 
Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI

EMDB-29344: 
Cryo-EM structure of human TRPV6 in the open state
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI
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