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Showing 1 - 50 of 75 items for (author: yelshanskaya & mv)
![](data/emdb/media/44123/emdbimg.jpg)
EMDB-44123:
Cryo-EM density of GluK2 amino-terminal domain (GluK2-ATD) from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44126/emdbimg.jpg)
EMDB-44126:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44127/emdbimg.jpg)
EMDB-44127:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44124/emdbimg.jpg)
EMDB-44124:
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44125/emdbimg.jpg)
EMDB-44125:
Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44128/emdbimg.jpg)
EMDB-44128:
Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44129/emdbimg.jpg)
EMDB-44129:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44130/emdbimg.jpg)
EMDB-44130:
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44131/emdbimg.jpg)
EMDB-44131:
Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/44132/emdbimg.jpg)
EMDB-44132:
Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer
Method: single particle / : Nadezhdin KD, Gangwar SP, Sobolevsky AI
![](data/emdb/media/42994/emdbimg.jpg)
EMDB-42994:
Apo-state cryo-EM structure of human TRPV3 in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI
![](data/emdb/media/42995/emdbimg.jpg)
EMDB-42995:
Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI
![](data/emdb/media/42996/emdbimg.jpg)
EMDB-42996:
Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI
![](data/emdb/media/42997/emdbimg.jpg)
EMDB-42997:
Open-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI
![](data/emdb/media/42998/emdbimg.jpg)
EMDB-42998:
Inactivated-state cryo-EM structure of human TRPV3 in presence of 2-APB in cNW30 nanodiscs
Method: single particle / : Nadezhdin KD, Neuberger A, Sobolevsky AI
![](data/emdb/media/16052/emdbimg.jpg)
EMDB-16052:
Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4
Method: single particle / : Absmeier E, Chandrasekaran V, O'Reilly FJ, Stowell JAW, Rappsilber J, Passmore LA
![](data/emdb/media/40741/emdbimg.jpg)
EMDB-40741:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40742/emdbimg.jpg)
EMDB-40742:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40743/emdbimg.jpg)
EMDB-40743:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40744/emdbimg.jpg)
EMDB-40744:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40745/emdbimg.jpg)
EMDB-40745:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40746/emdbimg.jpg)
EMDB-40746:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40747/emdbimg.jpg)
EMDB-40747:
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40748/emdbimg.jpg)
EMDB-40748:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40749/emdbimg.jpg)
EMDB-40749:
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40750/emdbimg.jpg)
EMDB-40750:
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/40676/emdbimg.jpg)
EMDB-40676:
Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV)
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI
![](data/emdb/media/29343/emdbimg.jpg)
EMDB-29343:
Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI
![](data/emdb/media/29344/emdbimg.jpg)
EMDB-29344:
Cryo-EM structure of human TRPV6 in the open state
Method: single particle / : Neuberger A, Yelshanskaya MV, Nadezhdin KD, Sobolevsky AI
![](data/emdb/media/29515/emdbimg.jpg)
EMDB-29515:
Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29516/emdbimg.jpg)
EMDB-29516:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29517/emdbimg.jpg)
EMDB-29517:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29518/emdbimg.jpg)
EMDB-29518:
Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29519/emdbimg.jpg)
EMDB-29519:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX
Method: single particle / : Yen LY, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29520/emdbimg.jpg)
EMDB-29520:
Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/29521/emdbimg.jpg)
EMDB-29521:
Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel
Method: single particle / : Gangwar SP, Yen LY, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26011/emdbimg.jpg)
EMDB-26011:
Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26012/emdbimg.jpg)
EMDB-26012:
Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26013/emdbimg.jpg)
EMDB-26013:
Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26014/emdbimg.jpg)
EMDB-26014:
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26015/emdbimg.jpg)
EMDB-26015:
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26016/emdbimg.jpg)
EMDB-26016:
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/26017/emdbimg.jpg)
EMDB-26017:
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Method: single particle / : Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24748/snaps2.jpg)
EMDB-24748:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24749/snaps2.jpg)
EMDB-24749:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24750/snaps2.jpg)
EMDB-24750:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24751/snaps2.jpg)
EMDB-24751:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775
Method: single particle / : Gangwar SP, Klykov OV, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24752/snaps2.jpg)
EMDB-24752:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24753/snaps2.jpg)
EMDB-24753:
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist Quisqualate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
![](data/emdb/media/24754/snaps2.jpg)
EMDB-24754:
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate
Method: single particle / : Klykov OV, Gangwar SP, Yelshanskaya MV, Sobolevsky AI
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