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Showing all 49 items for (author: gumpper & rh)

EMDB-44865: 
Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-44866: 
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-44945: 
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking local map
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-44946: 
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking, local refinement of heterotrimer
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-44961: 
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking global map
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-45616: 
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413 (Local Refinement)
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-43797: 
Local refinement of 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43798: 
Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43799: 
Local refinement of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43800: 
Global reconstruction of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43801: 
Local refinement of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43802: 
Global reconstruction of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43803: 
Local refinement of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43804: 
Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43805: 
Local refinement of 5-HT2AR bound to Mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43806: 
Global reconstruction of 5-HT2AR bound to mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43807: 
Local refinement of 5-HT2AR bound to psilocin in complex with a mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43808: 
Global reconstruction of 5-HT2AR bound to psilocin in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43809: 
Local refinement of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43810: 
Global reconstruction of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-42538: 
CryoEM Structure of HCA2-Gi1 in complex with MK-1903
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-42587: 
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-47113: 
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-2825
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

EMDB-47114: 
CryoEM structure of Gq-coupled MRGPRD with a new agonist EP-3945
Method: single particle / : Cao C, Wang C, Liu Y, Fay JF, Roth BL

EMDB-42999: 
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-43647: 
CryoEM structure of Gi-coupled TAS2R14 with cholesterol and an intracellular tastant
Method: single particle / : Kim Y, Gumpper RH, Roth BL

EMDB-43650: 
CryoEM structure of Ggust-coupled TAS2R14 with cholesterol and an intracellular tastant
Method: single particle / : Kim Y, Gumpper RH, Roth BL

EMDB-43656: 
CryoEM structure of Gi-coupled TAS2R14 with cholesterol and an intracellular tastant (Locally refined map)
Method: single particle / : Kim Y, Gumpper RH, Roth BL

EMDB-43657: 
CryoEM structure of Ggust-coupled TAS2R14 with cholesterol and an intracellular tastant (Locally refined map)
Method: single particle / : Kim Y, Gumpper RH, Roth BL

EMDB-27966: 
CryoEM structure of miniGq-coupled hM3Dq in complex with DCZ
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27967: 
CryoEM structure of miniGo-coupled hM4Di in complex with DCZ
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27968: 
CryoEM structure of miniGq-coupled hM3Dq in complex with CNO
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27969: 
CryoEM structure of miniGq-coupled hM3R in complex with Iperoxo
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27970: 
CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)
Method: single particle / : Zhang S, Fay JF, Roth BL

EMDB-27752: 
CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27753: 
CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-27754: 
CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16
Method: single particle / : Liu Y, Cao C, Fay JF, Roth BL

EMDB-25401: 
5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Cao C

EMDB-25402: 
5-HT2B receptor bound to LSD in complex with heterotrimeric mini-Gq protein obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K

EMDB-25403: 
5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Cao C, Panova O, Roth BL, Skiniotis G

EMDB-27633: 
Cryo-EM structure of the 5HT2C receptor (INI isoform) bound to lorcaserin
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-27634: 
Cryo-EM structure of the 5HT2C receptor (INI isoform) bound to psilocin
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-27635: 
Cryo-EM structure of the 5HT2C receptor (VGV isoform) bound to lorcaserin
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-27636: 
Cryo-EM structure of the 5HT2C receptor (VSV isoform) bound to lorcaserin
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-24896: 
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24897: 
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24898: 
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24899: 
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24900: 
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF
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