Author results

1NA6
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CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE ECORII MUTANT R88A
Descriptor:Restriction endonuclease EcoRII
Authors:Zhou, X.E., Wang, Y., Reuter, M., Mucke, M., Kruger, D.H., Meehan, E.J., Chen, L.
Deposit date:2002-11-26
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold.
J.Mol.Biol., 335, 2004
3L3X
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CRYSTAL STRUCTURE OF DHT-BOUND ANDROGEN RECEPTOR IN COMPLEX WITH THE FIRST MOTIF OF STEROID RECEPTOR COACTIVATOR 3
Descriptor:Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Zhou, X.E., Suino-Powell, K.M., Li, J., He, A., MacKeigan, J.P., Melcher, K., Yong, E.-L., Xu, H.E.
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3L3Z
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CRYSTAL STRUCTURE OF DHT-BOUND ANDROGEN RECEPTOR IN COMPLEX WITH THE THIRD MOTIF OF STEROID RECEPTOR COACTIVATOR 3
Descriptor:Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Zhou, X.E., Suino-Powell, K.M., Li, J., He, A., MacKeigan, J.P., Melcher, K., Yong, E.-L., Xu, H.E.
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3P0U
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN TESTICULAR RECEPTOR 4
Descriptor:Nuclear receptor subfamily 2 group C member 2
Authors:Zhou, X.E., Suino-Powell, K.M., Xu, Y., Chan, C.-W., Kruse, S.W., Reynolds, R., Engel, J.D., Xu, H.E.
Deposit date:2010-09-29
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor.
J.Biol.Chem., 286, 2011
5DGY
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO VISUAL ARRESTIN
Descriptor:Endolysin,Rhodopsin,S-arrestin
Authors:Zhou, X.E., Gao, X., Kang, Y., He, Y., de Waal, P.W., Suino-Powell, K.M., Wang, M., Melcher, K., Xu, H.E.
Deposit date:2015-08-28
Release date:2016-03-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (7.7 Å)
Cite:X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex.
Sci Data, 3, 2016
5W0P
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO VISUAL ARRESTIN DETERMINED BY X-RAY FREE ELECTRON LASER
Descriptor:Endolysin,Rhodopsin,S-arrestin, N-ACETYL-D-GLUCOSAMINE
Authors:Zhou, X.E., He, Y., de Waal, P.W., Gao, X., Kang, Y., Van Eps, N., Yin, Y., Pal, K., Goswami, D., White, T.A., Barty, A., Latorraca, N.R., Chapman, H.N., Hubbell, W.L., Dror, R.O., Stevens, R.C., Cherezov, V., Gurevich, V.V., Griffin, P.R., Ernst, O.P., Melcher, K., Xu, H.E.
Deposit date:2017-05-31
Release date:2017-08-09
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.013 Å)
Cite:Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Cell, 170, 2017
3GYT
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NUCLEAR RECEPTOR DAF-12 FROM PARASITIC NEMATODE STRONGYLOIDES STERCORALIS IN COMPLEX WITH ITS PHYSIOLOGICAL LIGAND DAFACHRONIC ACID DELTA 4
Descriptor:Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily, SRC1, (14beta,17alpha,25R)-3-oxocholest-4-en-26-oic acid
Authors:Zhou, X.E., Wang, Z., Suino-Powell, K., Motola, D.L., Conneely, A., Ogata, C., Sharma, K.K., Auchus, R.J., Kliewer, S.A., Xu, H.E., Mangelsdorf, D.J.
Deposit date:2009-04-05
Release date:2009-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GYU
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NUCLEAR RECEPTOR DAF-12 FROM PARASITIC NEMATODE STRONGYLOIDES STERCORALIS IN COMPLEX WITH ITS PHYSIOLOGICAL LIGAND DAFACHRONIC ACID DELTA 7
Descriptor:Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily, SRC1, (5beta,14beta,17alpha,25R)-3-oxocholest-7-en-26-oic acid
Authors:Zhou, X.E., Wang, Z., Suino-Powell, K., Motola, D.L., Conneely, A., Ogata, C., Sharma, K.K., Auchus, R.J., Kliewer, S.A., Xu, H.E., Mangelsdorf, D.J.
Deposit date:2009-04-05
Release date:2009-07-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Proc.Natl.Acad.Sci.USA, 106, 2009
3KAY
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CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL1
Descriptor:Putative uncharacterized protein At5g46790
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KAZ
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CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL2
Descriptor:Putative uncharacterized protein At2g26040, 1,3-BUTANEDIOL
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB0
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CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2
Descriptor:Putative uncharacterized protein At2g26040, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-19
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB3
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CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2 IN COMPLEX WITH HAB1
Descriptor:Putative uncharacterized protein At2g26040, Protein phosphatase 2C 16, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
Authors:Zhou, X.E., Melcher, K., Soon, F.-F., Ng, L.-M., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
Deposit date:2009-10-20
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3NMH
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CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 IN COMPLEX WITH PYRABACTIN
Descriptor:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMN
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CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL1 IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI1
Descriptor:Abscisic acid receptor PYL1, Protein phosphatase 2C 56, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMP
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CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH PYRABACTIN
Descriptor:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMT
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CRYSTAL STRUCTURE OF PYRABACTIN BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE HAB1
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 16, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMV
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CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI2
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 77, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
Authors:Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
Deposit date:2010-06-22
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3UC3
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THE CRYSTAL STRUCTURE OF SNF1-RELATED KINASE 2.3
Descriptor:Serine/threonine-protein kinase SRK2I, COBALT (II) ION
Authors:Zhou, X.E., Ng, L.-M., Soon, F.-F., Kovach, A., Suino-Powell, K.M., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-10-25
Release date:2011-12-14
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UC4
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THE CRYSTAL STRUCTURE OF SNF1-RELATED KINASE 2.6
Descriptor:Serine/threonine-protein kinase SRK2E
Authors:Zhou, X.E., Ng, L.-M., Soon, F.-F., Kovach, A., Suino-Powell, K.M., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-10-26
Release date:2011-12-14
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinases.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UJG
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CRYSTAL STRUCTURE OF SNRK2.6 IN COMPLEX WITH HAB1
Descriptor:Serine/threonine-protein kinase SRK2E, Protein phosphatase 2C 16, SULFATE ION, ...
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
3UJK
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CRYSTAL STRUCTURE OF PROTEIN PHOSPHATASE ABI2
Descriptor:Protein phosphatase 2C 77, MAGNESIUM ION
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
3UJL
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CRYSTAL STRUCTURE OF ABSCISIC ACID BOUND PYL2 IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI2
Descriptor:Abscisic acid receptor PYL2, Protein phosphatase 2C 77, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
Authors:Zhou, X.E., Soon, F.-F., Ng, L.-M., Kovach, A., Tan, M.H.E., Suino-Powell, K.M., He, Y., Xu, Y., Brunzelle, J.S., Li, J., Melcher, K., Xu, H.E.
Deposit date:2011-11-07
Release date:2012-02-15
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
4IH1
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CRYSTAL STRUCTURE OF KARRIKIN INSENSITIVE 2 (KAI2) FROM ARABIDOPSIS THALIANA
Descriptor:Hydrolase, alpha/beta fold family protein
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH4
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CRYSTAL STRUCTURE OF ARABIDOPSIS DWARF14 ORTHOLOGUE, ATD14
Descriptor:AT3g03990/T11I18_10
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
4IH9
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CRYSTAL STRUCTURE OF RICE DWARF14 (D14)
Descriptor:Dwarf 88 esterase
Authors:Zhou, X.E., Zhao, L.-H., Wu, Z.-S., Yi, W., Li, S., Li, Y., Xu, Y., Xu, T.-H., Liu, Y., Chen, R.-Z., Kovach, A., Kang, Y., Hou, L., He, Y., Zhang, C., Melcher, K., Xu, H.E.
Deposit date:2012-12-18
Release date:2013-01-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013