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5NF8
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SOLUTION STRUCTURE OF DETERGENT-SOLUBILIZED RCF1, A YEAST MITOCHONDRIAL INNER MEMBRANE PROTEIN INVOLVED IN RESPIRATORY COMPLEX III/IV SUPERCOMPLEX FORMATION
Descriptor:Respiratory supercomplex factor 1, mitochondrial
Authors:Zhou, S., Pettersson, P., Sjoholm, J., Sjostrand, D., Hogbom, M., Brzezinski, P., Maler, L., Adelroth, P.
Deposit date:2017-03-13
Release date:2018-02-28
Last modified:2018-03-28
Method:SOLUTION NMR
Cite:Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3OWG
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CRYSTAL STRUCTURE OF VACCINIA VIRUS POLYADENYLATE POLYMERASE(VP55)
Descriptor:Poly(A) polymerase catalytic subunit
Authors:Li, C., Li, H., Zhou, S., Gershon, P.D., Poulos, T.L.
Deposit date:2010-09-17
Release date:2011-09-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Domain-level rocking motion within a polymerase that translocates on single-stranded nucleic acid.
Acta Crystallogr.,Sect.D, 69, 2013
1J4P
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T155) PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-22
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1J4Q
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T192) PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-22
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1K3N
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T155) PEPTIDE
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1K3Q
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T192) PEPTIDE
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1FO8
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CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
Descriptor:ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE, METHYL MERCURY ION
Authors:Unligil, U.M., Zhou, S., Yuwaraj, S., Sarkar, M., Schachter, H., Rini, J.M.
Deposit date:2000-08-26
Release date:2001-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
1FO9
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CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
Descriptor:ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE
Authors:Unligil, U.M., Zhou, S., Yuwaraj, S., Sarkar, M., Schachter, H., Rini, J.M.
Deposit date:2000-08-26
Release date:2001-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
1FOA
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CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
Descriptor:ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE, MANGANESE (II) ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
Authors:Unligil, U.M., Zhou, S., Yuwaraj, S., Sarkar, M., Schachter, H., Rini, J.M.
Deposit date:2000-08-26
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
1J4O
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REFINED NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
Descriptor:PROTEIN KINASE SPK1
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1K3J
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REFINED NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
Descriptor:Protein Kinase SPK1
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
5NO2
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S4, 30S ribosomal protein S5, ...
Authors:Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO3
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE WITHOUT US3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
Authors:Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO4
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE WITH US3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
Deposit date:2017-04-10
Release date:2017-05-31
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (5.16 Å)
Cite:RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
1XZY
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SOLUTION STRUCTURE OF THE P30-TRANS FORM OF ALPHA HEMOGLOBIN STABILIZING PROTEIN (AHSP)
Descriptor:Alpha-hemoglobin stabilizing protein
Authors:Gell, D.A., Feng, L., Zhou, S., Kong, Y., Lee, C., Weiss, M.J., Shi, Y., Mackay, J.P.
Deposit date:2004-11-12
Release date:2004-12-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin
Cell(Cambridge,Mass.), 119, 2004
1Y01
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CRYSTAL STRUCTURE OF AHSP BOUND TO FE(II) ALPHA-HEMOGLOBIN
Descriptor:Alpha-hemoglobin stabilizing protein, Hemoglobin alpha chain, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Feng, L., Gell, D.A., Zhou, S., Gu, L., Gow, A.J., Weiss, M.J., Mackay, J.P., Shi, Y.
Deposit date:2004-11-14
Release date:2004-12-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin.
Cell(Cambridge,Mass.), 119, 2004
1Z8U
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CRYSTAL STRUCTURE OF OXIDIZED ALPHA HEMOGLOBIN BOUND TO AHSP
Descriptor:Alpha-hemoglobin stabilizing protein, Hemoglobin alpha chain, PROTOPORPHYRIN IX CONTAINING FE
Authors:Feng, L., Zhou, S., Gu, L., Gell, D.A., Mackay, J.P., Weiss, M.J., Gow, A.J., Shi, Y.
Deposit date:2005-03-31
Release date:2005-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of oxidized alpha-haemoglobin bound to AHSP reveals a protective mechanism for haem.
Nature, 435, 2005
2YB8
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CRYSTAL STRUCTURE OF NURF55 IN COMPLEX WITH SU(Z)12
Descriptor:POLYCOMB PROTEIN SU(Z)12, PROBABLE HISTONE-BINDING PROTEIN CAF1, SULFATE ION
Authors:Schmitges, F.W., Prusty, A.B., Faty, M., Stutzer, A., Lingaraju, G.M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R.D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks.
Mol.Cell, 42, 2011
2YBA
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CRYSTAL STRUCTURE OF NURF55 IN COMPLEX WITH HISTONE H3
Descriptor:PROBABLE HISTONE-BINDING PROTEIN CAF1, HISTONE H3
Authors:Schmitges, F.W., Prusty, A.B., Faty, M., Stutzer, A., Lingaraju, G.M., Aiwazian, J., Sack, R., Hess, D., Li, L., Zhou, S., Bunker, R.D., Wirth, U., Bouwmeester, T., Bauer, A., Ly-Hartig, N., Zhao, K., Chan, H., Gu, J., Gut, H., Fischle, W., Muller, J., Thoma, N.H.
Deposit date:2011-03-02
Release date:2011-05-11
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
3ER8
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE COMPLEX WITH TWO FRAGMENTS OF RNA
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
3ER9
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE COMPLEX WITH UU AND 3'-DEOXY ATP
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, 5'-R(UP*U)-3', ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
3ERC
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CRYSTAL STRUCTURE OF THE HETERODIMERIC VACCINIA VIRUS MRNA POLYADENYLATE POLYMERASE WITH THREE FRAGMENTS OF RNA AND 3'-DEOXY ATP
Descriptor:Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera (5'-D(CP*)R(UP*UP*)D(CP*C)-3'), ...
Authors:Li, C., Li, H., Zhou, S., Poulos, T.L., Gershon, P.D.
Deposit date:2008-10-01
Release date:2009-06-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Structure, 17, 2009
4YHH
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TIGECYCLINE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Dhimole, N., Zhou, S., Lopez-Alonso, J.P., Connell, S.R., Fucini, P.
Deposit date:2015-02-27
Release date:2015-04-08
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.417 Å)
Cite:Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
6IJH
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CRYSTAL STRUCTURE OF PDE10 IN COMPLEX WITH INHIBITOR AF-399/14387019
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Huang, Y.Y., Yu, Y.F., Zhang, C., Wu, D., Wu, Y., Luo, H.B.
Deposit date:2018-10-10
Release date:2019-04-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
J. Med. Chem., 2019
6IJI
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CRYSTAL STRUCTURE OF PDE10 IN COMPLEX WITH INHIBITOR 2B
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Huang, Y.Y., Yu, Y.F., Zhang, C., Wu, D., Wu, Y., Luo, H.B.
Deposit date:2018-10-10
Release date:2019-04-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
J. Med. Chem., 2019
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