5F17
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8JXO
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8JXP
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8IFU
| HcCCR in NaCl | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, HcCCR, RETINAL, ... | Authors: | Zhang, M.F. | Deposit date: | 2023-02-19 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.37 Å) | Cite: | Structure of HcCCR To Be Published
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8IO5
| Herg1a-herg1b closed state 2 | Descriptor: | Potassium voltage-gated channel subfamily H member 2 | Authors: | Zhang, M.F. | Deposit date: | 2023-03-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of Herg1a-herg1b open state To Be Published
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8IOB
| Herg1a-herg1b closed state 1 | Descriptor: | Potassium voltage-gated channel subfamily H member 2 | Authors: | Zhang, M.F. | Deposit date: | 2023-03-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of Herg1a-herg1b closed state 1 To Be Published
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8IO4
| Herg1a-herg1b open state | Descriptor: | Potassium voltage-gated channel subfamily H member 2 | Authors: | Zhang, M.F. | Deposit date: | 2023-03-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of Herg1a-herg1b open state To Be Published
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7XTK
| Cryo-EM structure of SLC19A1 | Descriptor: | Reduced folate transporter | Authors: | Zhang, M.F, Shan, Y.Y. | Deposit date: | 2022-05-17 | Release date: | 2023-06-21 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of human SLC19A1. To Be Published
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7XYM
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5EYI
| Structure of PRRSV apo-NSP11 at 2.16A | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Non-structural protein 11, ... | Authors: | Zhang, M.F, Chen, Z. | Deposit date: | 2015-11-25 | Release date: | 2016-10-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Structural Biology of the Arterivirus nsp11 Endoribonucleases. J. Virol., 91, 2017
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7V1U
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide | Authors: | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | Deposit date: | 2021-08-06 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Acta Pharmacol.Sin., 43, 2022
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7V2J
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 33 | Descriptor: | Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-4-methoxy-benzenesulfonamide | Authors: | Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. | Deposit date: | 2021-08-09 | Release date: | 2022-08-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Acta Pharmacol.Sin., 43, 2022
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5HBZ
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5HC1
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8W6A
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8W6B
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8GRS
| human TMEM63A | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CSC1-like protein 1 | Authors: | Zhang, M.F. | Deposit date: | 2022-09-02 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8GRN
| AtOSCA1.1 extended state | Descriptor: | Protein OSCA1, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE | Authors: | Zhang, M.F. | Deposit date: | 2022-09-02 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8GSO
| AtOSCA3.1 channel extended state | Descriptor: | CSC1-like protein ERD4 | Authors: | Zhang, M.F. | Deposit date: | 2022-09-06 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8GRO
| AtOSCA3.1 contracted state | Descriptor: | CSC1-like protein ERD4 | Authors: | Zhang, M.F. | Deposit date: | 2022-09-02 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nat Commun, 14, 2023
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8ZAO
| ExoKCR1 channelrhodopsin | Descriptor: | POTASSIUM ION, RETINAL, exoKCR1 | Authors: | Zhang, M.F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Channelrhodopsins with distinct chromophores and binding patterns. Nat Commun, 15, 2024
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8ZAP
| ExoC110T class 1 channelrhodopsin | Descriptor: | C110T-class1, POTASSIUM ION, RETINAL | Authors: | Zhang, M.F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Channelrhodopsins with distinct chromophores and binding patterns. Nat Commun, 15, 2024
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8ZAQ
| ExoC110T class 2 channelrhodopsin | Descriptor: | C110T class2, POTASSIUM ION, RETINAL | Authors: | Zhang, M.F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Channelrhodopsins with distinct chromophores and binding patterns. Nat Commun, 15, 2024
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8ZAN
| ExoChR2 channelrhodopsin | Descriptor: | Archaeal-type opsin 2, RETINAL | Authors: | Zhang, M.F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Channelrhodopsins with distinct chromophores and binding patterns. Nat Commun, 15, 2024
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8ZAM
| EndoChR2 channelrhodopsin | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2 | Authors: | Zhang, M.F. | Deposit date: | 2024-04-25 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Channelrhodopsins with distinct chromophores and binding patterns. Nat Commun, 15, 2024
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