Author results

2HC9
  • Download 2hc9
  • View 2hc9
Molmil generated image of 2hc9
STRUCTURE OF CAENORHABDITIS ELEGANS LEUCINE AMINOPEPTIDASE-ZINC COMPLEX (LAP1)
Descriptor:Leucine aminopeptidase 1, ZINC ION, BICARBONATE ION, ...
Authors:Zhan, C., Patskovsky, Y., Wengerter, B.C., Ramagopal, U., Milstein, S., Vidal, M., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-15
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure and Function of Caenorhabditis Elegans Leucine Aminopeptidase
To be Published
2QE3
  • Download 2qe3
  • View 2qe3
Molmil generated image of 2qe3
CRYSTAL STRUCTURE OF HUMAN TL1A EXTRACELLULAR DOMAIN
Descriptor:TNF superfamily ligand TL1A, CHLORIDE ION
Authors:Zhan, C., Yan, Q., Patskovsky, Y., Shi, W., Toro, R., Bonanno, J., Nathenson, S.G., Almo, S.C.
Deposit date:2007-06-22
Release date:2007-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2RJK
  • Download 2rjk
  • View 2rjk
Molmil generated image of 2rjk
CRYSTAL STRUCTURE OF HUMAN TL1A EXTRACELLULAR DOMAIN C95S MUTANT
Descriptor:TNF superfamily ligand TL1A
Authors:Zhan, C., Yan, Q., Patskovsky, Y., Shi, W., Ramagopal, U.A., Toro, R., Bonanno, J., Nathenson, S.G., Almo, S.C.
Deposit date:2007-10-15
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
2RJL
  • Download 2rjl
  • View 2rjl
Molmil generated image of 2rjl
CRYSTAL STRUCTURE OF HUMAN TL1A EXTRACELLULAR DOMAIN C95S/C135S MUTANT
Descriptor:TNF superfamily ligand TL1A
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Shi, W., Toro, R., Bonanno, J., Nathenson, S.G., Almo, S.C.
Deposit date:2007-10-15
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Biochemical and structural characterization of the human TL1A ectodomain.
Biochemistry, 48, 2009
3K51
  • Download 3k51
  • View 3k51
Molmil generated image of 3k51
CRYSTAL STRUCTURE OF DCR3-TL1A COMPLEX
Descriptor:Tumor necrosis factor ligand superfamily member 15, secreted form, Decoy receptor 3
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2009-10-06
Release date:2010-10-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3MHD
  • Download 3mhd
  • View 3mhd
Molmil generated image of 3mhd
CRYSTAL STRUCTURE OF DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2010-04-07
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3MI8
  • Download 3mi8
  • View 3mi8
Molmil generated image of 3mi8
THE STRUCTURE OF TL1A-DCR3 COMPLEX
Descriptor:TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED FORM, Tumor necrosis factor receptor superfamily member 6B
Authors:Zhan, C., Patskovsky, Y., Yan, Q., Li, Z., Ramagopal, U.A., Nathenson, S.G., Almo, S.C.
Deposit date:2010-04-09
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
4J1R
  • Download 4j1r
  • View 4j1r
Molmil generated image of 4j1r
CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH INHIBITOR 15R
Descriptor:Glycogen synthase kinase-3 beta, PHOSPHATE ION, (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, ...
Authors:Zhan, C., Wang, Y., Wach, J., Sheehan, P., Zhong, C., Harris, R., Patskovsky, Y., Bishop, J., Haggarty, S., Ramek, A., Berry, K., O'Herin, C., Koehler, A.N., Hung, A.W., Young, D.W., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-01
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
4J71
  • Download 4j71
  • View 4j71
Molmil generated image of 4j71
CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH INHIBITOR 1R
Descriptor:Glycogen synthase kinase-3 beta, (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, SULFATE ION, ...
Authors:Zhan, C., Wang, Y., Wach, J., Sheehan, P., Zhong, C., Harris, R., Patskovsky, Y., Bishop, J., Haggarty, S., Ramek, A., Berry, K., O'Herin, C., Koehler, A.N., Hung, A.W., Young, D.W., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-12
Release date:2013-03-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
2HB6
  • Download 2hb6
  • View 2hb6
Molmil generated image of 2hb6
STRUCTURE OF CAENORHABDITIS ELEGANS LEUCINE AMINOPEPTIDASE (LAP1)
Descriptor:Leucine aminopeptidase 1, SULFATE ION, SODIUM ION, ...
Authors:Patskovsky, Y., Zhan, C., Wengerter, B.C., Ramagopal, U., Milstein, S., Vidal, M., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-06-13
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Caenorhabditis Elegans Leucine Aminopeptidase
To be Published
4EN0
  • Download 4en0
  • View 4en0
Molmil generated image of 4en0
CRYSTAL STRUCTURE OF LIGHT
Descriptor:Tumor necrosis factor ligand superfamily member 14, PHOSPHATE ION, GLYCEROL, ...
Authors:Zhan, C., Liu, W., Patskovsky, Y., Ramagopal, U.A., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
2RDM
  • Download 2rdm
  • View 2rdm
Molmil generated image of 2rdm
CRYSTAL STRUCTURE OF RESPONSE REGULATOR RECEIVER PROTEIN FROM SINORHIZOBIUM MEDICAE WSM419
Descriptor:Response regulator receiver protein, GLYCEROL
Authors:Patskovsky, Y., Yan, Q., Zhan, C., Toro, R., Meyer, A.J., Gilmore, M., Hu, S., Groshong, C., Rodgers, L., Sauder, J.M., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-09-24
Release date:2007-10-09
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of response regulator receiver protein from Sinorhizobium medicae WSM419.
To be Published
2G64
  • Download 2g64
  • View 2g64
Molmil generated image of 2g64
STRUCTURE OF CAENORHABDITIS ELEGANS 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE
Descriptor:Putative 6-pyruvoyl tetrahydrobiopterin synthase, SODIUM ION, ZINC ION, ...
Authors:Wengerter, B.C., Patskovsky, Y., Zhan, C., Ramagopal, U., Milstein, S., Vidal, M., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-02-24
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Caenorhabditis Elegans 6-Pyruvoyl Tetrahydropterin Synthase
To be Published
2O3J
  • Download 2o3j
  • View 2o3j
Molmil generated image of 2o3j
STRUCTURE OF CAENORHABDITIS ELEGANS UDP-GLUCOSE DEHYDROGENASE
Descriptor:UDP-glucose 6-dehydrogenase, GLYCEROL
Authors:Zhang, Y., Zhan, C., Patskovsky, Y., Ramagopal, U., Shi, W., Toro, R., Wengerter, B.C., Milst, S., Vidal, M., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-12-01
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal Structure of Caenorhabditis Elegans Udp-Glucose Dehydrogenase
To be Published
2PMB
  • Download 2pmb
  • View 2pmb
Molmil generated image of 2pmb
CRYSTAL STRUCTURE OF PREDICTED NUCLEOTIDE-BINDING PROTEIN FROM VIBRIO CHOLERAE
Descriptor:Uncharacterized protein, PHOSPHATE ION, GLYCEROL
Authors:Patskovsky, Y., Zhan, C., Shi, W., Toro, R., Sauder, J.M., Gilmore, J., Iizuka, M., Maletic, M., Gheyi, T., Wasserman, S.R., Smith, D., Burley, S.K., Almo, S.C., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-04-20
Release date:2007-05-08
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Crystal Structure of Predicted Nucleotide-Binding Protein from Vibrio Cholerae.
To be Published
3FOW
  • Download 3fow
  • View 3fow
Molmil generated image of 3fow
PLASMODIUM PURINE NUCLEOSIDE PHOSPHORYLASE V66I-V73I-Y160F MUTANT
Descriptor:Uridine phosphorylase, putative, PHOSPHATE ION, ...
Authors:Donaldson, T., Zhan, C.
Deposit date:2009-01-02
Release date:2009-12-29
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase.
Plos One, 9, 2014
4FHQ
  • Download 4fhq
  • View 4fhq
Molmil generated image of 4fhq
CRYSTAL STRUCTURE OF HVEM
Descriptor:Tumor necrosis factor receptor superfamily member 14
Authors:Liu, W., Zhan, C., Patskovsky, Y., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-06-06
Release date:2012-07-18
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
Mol Biotechnol, 57, 2015
4J6G
  • Download 4j6g
  • View 4j6g
Molmil generated image of 4j6g
CRYSTAL STRUCTURE OF LIGHT AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor ligand superfamily member 14, Tumor necrosis factor receptor superfamily member 6B, CHLORIDE ION, ...
Authors:Liu, W., Zhan, C., Bonanno, J.B., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-11
Release date:2013-03-13
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4KG8
  • Download 4kg8
  • View 4kg8
Molmil generated image of 4kg8
CRYSTAL STRUCTURE OF LIGHT MUTANT
Descriptor:Tumor necrosis factor ligand superfamily member 14
Authors:Liu, W., Zhan, C., Kumar, P.R., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-04-28
Release date:2013-08-07
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4KGG
  • Download 4kgg
  • View 4kgg
Molmil generated image of 4kgg
CRYSTAL STRUCTURE OF LIGHT MUTANT2 AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14, MAGNESIUM ION, ...
Authors:Liu, W., Bonanno, J.B., Zhan, C., Kumar, P.R., Toro, R., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-04-29
Release date:2013-08-07
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4KGQ
  • Download 4kgq
  • View 4kgq
Molmil generated image of 4kgq
CRYSTAL STRUCTURE OF A HUMAN LIGHT LOOP MUTANT IN COMPLEX WITH DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14, MAGNESIUM ION, ...
Authors:Liu, W., Zhan, C., Bonanno, J.B., Sampathkumar, P., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-04-29
Release date:2013-07-10
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4MSV
  • Download 4msv
  • View 4msv
Molmil generated image of 4msv
CRYSTAL STRUCTURE OF FASL AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 6, MAGNESIUM ION, ...
Authors:Liu, W., Ramagopal, U.A., Zhan, C., Bonanno, J.B., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-09-18
Release date:2013-11-27
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
5F6D
  • Download 5f6d
  • View 5f6d
Molmil generated image of 5f6d
CRYSTAL STRUCTURE OF UBC9 (K48A/K49A/E54A) COMPLEXED WITH FRAGMENT 6
Descriptor:SUMO-conjugating enzyme UBC9, 6~{H}-benzo[c][1,2]benzothiazine 5,5-dioxide
Authors:Lountos, G.T., Hewitt, W.M., Zlotkowski, K., Dahlhauser, S., Saunders, L.B., Needle, D., Tropea, J.E., Zhan, C., Wei, G., Ma, B., Nussinov, R., Schneekloth, J.S.Jr., Waugh, D.S.
Deposit date:2015-12-05
Release date:2016-04-27
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (1.553 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6E
  • Download 5f6e
  • View 5f6e
Molmil generated image of 5f6e
CRYSTAL STRUCTURE OF HUMAN UBC9 (K48A/K49A/E54A)
Descriptor:SUMO-conjugating enzyme UBC9, 1,2-ETHANEDIOL
Authors:Lountos, G.T., Hewitt, W.M., Zlotkowski, Z., Dahlhauser, S., Saunders, L.B., Needle, D., Tropea, J.E., Zhan, C., Wei, G., Ma, B., Nussinov, R., Schneekloth, J.S.Jr., Waugh, D.S.
Deposit date:2015-12-05
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
5F6U
  • Download 5f6u
  • View 5f6u
Molmil generated image of 5f6u
CRYSTAL STRUCTURE OF UBC9 (K48A/K49A/E54A) COMPLEXED WITH FRAGMENT 8 (JSS190B146)
Descriptor:SUMO-conjugating enzyme UBC9, ethyl 3-[4-(2-hydroxyphenyl)-3-oxidanyl-phenyl]propanoate
Authors:Lountos, G.T., Hewitt, W.M., Zlotkowski, Z., Dahlhauser, S., Saunders, L.B., Needle, D., Tropea, J.E., Zhan, C., Wei, G., Ma, B., Nussinov, R., Schneekloth, J.S.Jr., Waugh, D.S.
Deposit date:2015-12-07
Release date:2016-04-27
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.
Angew.Chem.Int.Ed.Engl., 55, 2016
<12>