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2A6H
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME IN COMPLEX WITH ANTIBIOTIC STERPTOLYDIGIN
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Temiakov, D., Zenkin, N., Vassylyeva, M.N., Perederina, A., Tahirov, T.H., Savkina, M., Zorov, S., Nikiforov, V., Igarashi, N., Matsugaki, N., Wakatsuki, S., Severinov, K., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
5MI3
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STRUCTURE OF PHOSPHORYLATED TRANSLATION ELONGATION FACTOR EF-TU FROM E. COLI
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI8
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STRUCTURE OF THE PHOSPHOMIMETIC MUTANT OF EF-TU T383E
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI9
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STRUCTURE OF THE PHOSPHOMIMETIC MUTANT OF THE ELONGATION FACTOR EF-TU T62E
Descriptor:Elongation factor Tu 1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Talavera, A., Hendrix, J., Versees, W., De Gieter, S., Castro-Roa, D., Jurenas, D., Van Nerom, K., Vandenberk, N., Barth, A., De Greve, H., Hofkens, J., Zenkin, N., Loris, R., Garcia-Pino, A.
Deposit date:2016-11-27
Release date:2017-12-20
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
1YNN
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TAQ RNA POLYMERASE-RIFAMPICIN COMPLEX
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1YNJ
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TAQ RNA POLYMERASE-SORANGICIN COMPLEX
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A., Pavlova, O., Zenkin, N., Leon, F., Irschik, H., Jansen, R., Severinov, K., Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
6CUU
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THERMUS THERMOPHILES RNA POLYMERASE IN COMPLEX WITH PROMOTER DNA AND ANTIBIOTIC KANGLEMYCIN A
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Molodtsov, V., Murakami, K.S.
Deposit date:2018-03-26
Release date:2018-07-25
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.
Mol. Cell, 72, 2018
6CUX
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ESCHERICHIA COLI RPOB S531L MUTANT RNA POLYMERASE HOLOENZYME IN COMPLEX WITH KANGLEMYCIN A
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Molodtsov, V., Murakami, K.S.
Deposit date:2018-03-26
Release date:2018-07-25
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (4.104 Å)
Cite:Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.
Mol. Cell, 72, 2018
2A6E
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CRYSTAL STRUCTURE OF THE T. THERMOPHILUS RNA POLYMERASE HOLOENZYME
Descriptor:DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I., Vassylyeva, M.N., Svetlov, D., Svetlov, V., Perederina, A., Igarashi, N., Matsugaki, N., Wakatsuki, S., Tahirov, T.H., Vassylyev, D.G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-07-02
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005