2KKF
| Solution structure of MLL CXXC domain in complex with palindromic CPG DNA | Descriptor: | 5'-D(*CP*CP*CP*TP*GP*CP*GP*CP*AP*GP*GP*G)-3', Histone-lysine N-methyltransferase HRX, ZINC ION | Authors: | Cierpicki, T, Riesbeck, J.E, Grembecka, J.E, Lukasik, S.M, Popovic, R, Omonkowska, M, Shultis, D.S, Zeleznik-Le, N.J, Bushweller, J.H. | Deposit date: | 2009-06-18 | Release date: | 2009-12-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the MLL CXXC domain-DNA complex and its functional role in MLL-AF9 leukemia. Nat.Struct.Mol.Biol., 17, 2010
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6B7G
| Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9) | Descriptor: | BCL-6 corepressor, Protein AF-9 | Authors: | Schmidt, C.R, Kuntimaddi, A, Leach, B.I, Bushweller, J.H. | Deposit date: | 2017-10-04 | Release date: | 2018-10-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discov, 1, 2020
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2MV7
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1JSP
| NMR Structure of CBP Bromodomain in complex with p53 peptide | Descriptor: | CREB-BINDING PROTEIN, tumor protein p53 | Authors: | He, Y, Mujtaba, S, Zeng, L, Yan, S, Zhou, M.-M. | Deposit date: | 2001-08-17 | Release date: | 2002-08-17 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. Mol.Cell, 13, 2004
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2JYI
| Solution structure of MLL CXXC domain | Descriptor: | ZINC ION, Zinc finger protein HRX | Authors: | Cierpicki, T, Bushweller, J.H. | Deposit date: | 2007-12-13 | Release date: | 2008-12-09 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structural basis for maintenance of unmethylated CpG elements by the CXXC domain of MLL and its critical contributions to MLL-AF9 immortalization activity To be Published
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