6B7G
Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9)
Summary for 6B7G
Entry DOI | 10.2210/pdb6b7g/pdb |
Related | 2LM0 2MV7 2N4Q |
NMR Information | BMRB: 27271 |
Descriptor | Protein AF-9, BCL-6 corepressor (2 entities in total) |
Functional Keywords | complex, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 11991.55 |
Authors | Schmidt, C.R.,Kuntimaddi, A.,Leach, B.I.,Bushweller, J.H. (deposition date: 2017-10-04, release date: 2018-10-10, Last modification date: 2023-06-14) |
Primary citation | Schmidt, C.R.,Achille, N.J.,Kuntimaddi, A.,Boulton, A.M.,Leach, B.I.,Zhang, S.,Zeleznik-Le, N.J.,Bushweller, J.H. BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity. Blood Cancer Discov, 1:162-177, 2020 Cited by PubMed: 32954361DOI: 10.1158/2643-3230.BCD-20-0036 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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