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6B7G

Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9)

Summary for 6B7G
Entry DOI10.2210/pdb6b7g/pdb
Related2LM0 2MV7 2N4Q
NMR InformationBMRB: 27271
DescriptorProtein AF-9, BCL-6 corepressor (2 entities in total)
Functional Keywordscomplex, transcription
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight11991.55
Authors
Schmidt, C.R.,Kuntimaddi, A.,Leach, B.I.,Bushweller, J.H. (deposition date: 2017-10-04, release date: 2018-10-10, Last modification date: 2023-06-14)
Primary citationSchmidt, C.R.,Achille, N.J.,Kuntimaddi, A.,Boulton, A.M.,Leach, B.I.,Zhang, S.,Zeleznik-Le, N.J.,Bushweller, J.H.
BCOR Binding to MLL-AF9 Is Essential for Leukemia via Altered EYA1, SIX, and MYC Activity.
Blood Cancer Discov, 1:162-177, 2020
Cited by
PubMed: 32954361
DOI: 10.1158/2643-3230.BCD-20-0036
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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