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6R64
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BU of 6r64 by Molmil
N-terminal domain of modification dependent EcoKMcrA restriction endonuclease (NEco) in complex with C5mCGG target sequence
Descriptor: 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*(5CM)P*GP*GP*TP*TP*C)-3')
Authors:Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M.
Deposit date:2019-03-26
Release date:2019-10-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
8PVV
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BU of 8pvv by Molmil
Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 30 nt RNA guide and 51 nt DNA target
Descriptor: Archaeoglobus fulgidus AfAgo-N protein, DNA (51-MER), MAGNESIUM ION, ...
Authors:Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Sasnauskas, G, Zagorskaite, E, Silanskas, A.
Deposit date:2023-07-18
Release date:2024-01-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
6T22
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BU of 6t22 by Molmil
N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5hmCGA target sequence
Descriptor: DNA (5'-D(*GP*AP*AP*TP*(5HC)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5HC)P*GP*AP*TP*TP*C)-3'), EcoKMcrA modification dependent restriction endonuclease
Authors:Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M.
Deposit date:2019-10-07
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
6T21
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BU of 6t21 by Molmil
N-terminal domain of EcoKMcrA restriction endonuclease (NEco) in complex with T5mCGA target sequence
Descriptor: 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*TP*(5CM)P*GP*AP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*TP*(5CM)P*GP*AP*TP*TP*C)-3')
Authors:Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M.
Deposit date:2019-10-07
Release date:2019-10-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Nucleic Acids Res., 47, 2019
8QG0
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BU of 8qg0 by Molmil
Archaeoglobus fulgidus AfAgo complex with AfAgo-N protein (fAfAgo) bound with 17 nt RNA guide and 17 nt DNA target
Descriptor: AfAgo-N protein, DNA target 17 nt, Piwi protein, ...
Authors:Manakova, E.N, Zaremba, M, Pocevicuite, R, Golovinas, E, Zagorskaite, E, Silanskas, A.
Deposit date:2023-09-05
Release date:2024-01-24
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
6GHC
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BU of 6ghc by Molmil
Modification dependent EcoKMcrA restriction endonuclease
Descriptor: 5-methylcytosine-specific restriction enzyme A, ZINC ION
Authors:Czapinska, H, Kowalska, M, Zagorskaite, E, Manakova, E, Xu, S, Siksnys, V, Sasnauskas, G, Bochtler, M.
Deposit date:2018-05-07
Release date:2018-08-08
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Activity and structure of EcoKMcrA.
Nucleic Acids Res., 46, 2018
6GCD
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BU of 6gcd by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with 5-hydroxymethylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*(5HC)P*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5HC)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G, Manakova, E.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
6GCF
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BU of 6gcf by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with N4-methylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(C34)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
6GCE
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BU of 6gce by Molmil
DNA binding domain of restriction endonuclease McrBC in complex with 5-formylcytosine DNA
Descriptor: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5FC)P*CP*GP*GP*TP*CP*TP*C)-3')
Authors:Sasnauskas, G.
Deposit date:2018-04-17
Release date:2018-09-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.
FEBS Lett., 592, 2018
8OK9
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BU of 8ok9 by Molmil
Heterodimeric complex of Archaeoglobus fulgidus Argonaute protein Af1318 (AfAgo) with DNA and AfAgo-N protein containing N-L1-L2 domains
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Archaeoglobus fulgidus AfAgo-N protein, ...
Authors:Manakova, E.N, Zaremba, M.
Deposit date:2023-03-27
Release date:2024-01-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
8OLD
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BU of 8old by Molmil
Crystal structure of Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains, CACODYLATE ION, ...
Authors:Manakova, E.N, Zaremba, M, Grazulis, S.
Deposit date:2023-03-30
Release date:2024-01-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
8OLJ
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BU of 8olj by Molmil
Crystal structure of Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, Archaeoglobus fulgidus AfAgo-N protein representing N-L1-L2 domains, ...
Authors:Manakova, E.N, Zaremba, M, Grazulis, S.
Deposit date:2023-03-30
Release date:2024-01-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
4RZL
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BU of 4rzl by Molmil
DNA recognition domain of the cytosine modification-dependent restriction endonuclease LpnPI
Descriptor: PENTAETHYLENE GLYCOL, Restriction endonuclease LpnPI
Authors:Sasnauskas, G, Tamulaitiene, G, Siksnys, V.
Deposit date:2014-12-22
Release date:2015-06-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI.
Nucleic Acids Res., 43, 2015

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PDB entries from 2024-04-24

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