Author results

1NPM
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NEUROPSIN, A SERINE PROTEASE EXPRESSED IN THE LIMBIC SYSTEM OF MOUSE BRAIN
Descriptor:NEUROPSIN, N-ACETYL-D-GLUCOSAMINE
Authors:Kishi, T., Kato, M., Shimizu, T., Kato, K., Matsumoto, K., Yoshida, S., Shiosaka, S., Hakoshima, T.
Deposit date:1998-01-07
Release date:1999-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of neuropsin, a hippocampal protease involved in kindling epileptogenesis.
J.Biol.Chem., 274, 1999
5YGY
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CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH (S)-N-(3-(2-AMINO-6-(FLUOROMETHYL)-4 -METHYL-4H-1,3-OXAZIN-4-YL)-4-FLUOROPHENYL)-5-CYANOPICOLINAMIDE
Descriptor:Beta-secretase 1, IODIDE ION, GLYCEROL, ...
Authors:Fuchino, K., Mitsuoka, Y., Masui, M., Kurose, N., Yoshida, S., Komano, K., Yamamoto, T., Ogawa, M., Unemura, C., Hosono, M., Ito, H., Sakaguchi, G., Ando, S., Ohnishi, S., Kido, Y., Fukushima, T., Miyajima, H., Hiroyama, S., Koyabu, K., Dhuyvetter, D., Borghys, H., Gijsen, H., Yamano, Y., Iso, Y., Kusakabe, K.
Deposit date:2017-09-27
Release date:2018-05-23
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational Design of Novel 1,3-Oxazine Based beta-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust A beta Reduction in the Brain
J. Med. Chem., 61, 2018
3A11
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CRYSTAL STRUCTURE OF RIBOSE-1,5-BISPHOSPHATE ISOMERASE FROM THERMOCOCCUS KODAKARAENSIS KOD1
Descriptor:Translation initiation factor eIF-2B, delta subunit, DI(HYDROXYETHYL)ETHER, ...
Authors:Nakamura, A., Fujihashi, M., Nishiba, Y., Yoshida, S., Yano, A., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-03-25
Release date:2010-03-31
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1
J.Biol.Chem., 287, 2012
3A12
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CRYSTAL STRUCTURE OF TYPE III RUBISCO COMPLEXED WITH 2-CABP
Descriptor:Ribulose bisphosphate carboxylase, MAGNESIUM ION, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE
Authors:Nishitani, Y., Fujihashi, M., Doi, T., Yoshida, S., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based catalytic optimization of a type III Rubisco from a hyperthermophile
J.Biol.Chem., 285, 2010
3A13
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CRYSTAL STRUCTURE OF TYPE III RUBISCO SP4 MUTANT COMPLEXED WITH 2-CABP AND ACTIVATED WITH CA
Descriptor:Ribulose bisphosphate carboxylase, MAGNESIUM ION, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, ...
Authors:Nishitani, Y., Fujihashi, M., Doi, T., Yoshida, S., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Sturcture-based optimization of a Type III Rubisco from a hyperthermophile
To be Published
3A9C
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CRYSTAL STRUCTURE OF RIBOSE-1,5-BISPHOSPHATE ISOMERASE FROM THERMOCOCCUS KODAKARAENSIS KOD1 IN COMPLEX WITH RIBULOSE-1,5-BISPHOSPHATE
Descriptor:Translation initiation factor eIF-2B, delta subunit, RIBULOSE-1,5-DIPHOSPHATE, ...
Authors:Nakamura, A., Fujihashi, M., Nishiba, Y., Yoshida, S., Yano, A., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-10-22
Release date:2010-11-03
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1
J.Biol.Chem., 287, 2012
3KDN
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CRYSTAL STRUCTURE OF TYPE III RUBISCO SP4 MUTANT COMPLEXED WITH 2-CABP
Descriptor:Ribulose bisphosphate carboxylase, MAGNESIUM ION, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE
Authors:Nishitani, Y., Fujihashi, M., Doi, T., Yoshida, S., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-10-23
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure-based catalytic optimization of a type III Rubisco from a hyperthermophile
J.Biol.Chem., 285, 2010
3KDO
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CRYSTAL STRUCTURE OF TYPE III RUBISCO SP6 MUTANT COMPLEXED WITH 2-CABP
Descriptor:Ribulose bisphosphate carboxylase, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION
Authors:Nishitani, Y., Fujihashi, M., Doi, T., Yoshida, S., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2009-10-23
Release date:2010-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structure-based catalytic optimization of a type III Rubisco from a hyperthermophile
J.Biol.Chem., 285, 2010
3VM6
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CRYSTAL STRUCTURE OF RIBOSE-1,5-BISPHOSPHATE ISOMERASE FROM THERMOCOCCUS KODAKARENSIS KOD1 IN COMPLEX WITH ALPHA-D-RIBOSE-1,5-BISPHOSPHATE
Descriptor:Translation initiation factor eIF-2B, delta subunit, 1,5-di-O-phosphono-alpha-D-ribofuranose, ...
Authors:Nakamura, A., Fujihashi, M., Aono, R., Sato, T., Nishiba, Y., Yoshida, S., Yano, A., Atomi, H., Imanaka, T., Miki, K.
Deposit date:2011-12-08
Release date:2012-04-25
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1
J.Biol.Chem., 287, 2012
1MY6
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THE 1.6 A STRUCTURE OF FE-SUPEROXIDE DISMUTASE FROM THE THERMOPHILIC CYANOBACTERIUM THERMOSYNECHOCOCCUS ELONGATUS : CORRELATION OF EPR AND STRUCTURAL CHARACTERISTICS
Descriptor:Iron (III) Superoxide Dismutase, FE (III) ION
Authors:Yoshida, S.M., Cascio, D., Sawaya, M.R., Yeates, T.O., Kerfeld, C.A.
Deposit date:2002-10-03
Release date:2003-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus.
J.BIOL.INORG.CHEM., 8, 2003
1LTH
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T AND R STATES IN THE CRYSTALS OF BACTERIAL L-LACTATE DEHYDROGENASE REVEAL THE MECHANISM FOR ALLOSTERIC CONTROL
Descriptor:L-LACTATE DEHYDROGENASE (T- AND R- STATE TETRAMER COMPLEX), BETA-FRUCTOSE-1,6-DIPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Iwata, S., Ohta, T.
Deposit date:1995-01-04
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:T and R states in the crystals of bacterial L-lactate dehydrogenase reveal the mechanism for allosteric control.
Nat.Struct.Biol., 1, 1994
1XYF
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ENDO-1,4-BETA-XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS
Descriptor:ENDO-1,4-BETA-XYLANASE
Authors:Fujimoto, Z., Mizuno, H., Kuno, A., Kusakabe, I.
Deposit date:1999-05-11
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Streptomyces olivaceoviridis E-86 beta-xylanase containing xylan-binding domain.
J.Mol.Biol., 300, 2000
2D1Z
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CRYSTAL STRUCTURE OF CATALYTIC-SITE MUTANT XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86
Descriptor:ENDO-1,4-BETA-D-XYLANASE, SULFATE ION, GLYCEROL
Authors:Suzuki, R., Kuno, A., Fujimoto, Z., Ito, S., Kawahara, S.I., Kaneko, S., Hasegawa, T., Taira, K.
Deposit date:2005-09-02
Release date:2006-10-10
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
2D20
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CRYSTAL STRUCTURE OF MICHAELIS COMPLEX OF CATALYTIC-SITE MUTANT XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86
Descriptor:ENDO-1,4-BETA-D-XYLANASE, XYLOPYRANOSE, P-NITROPHENOL, ...
Authors:Suzuki, R., Kuno, A., Fujimoto, Z., Ito, S., Kawahara, S.I., Kaneko, S., Hasegawa, T., Taira, K.
Deposit date:2005-09-02
Release date:2006-10-10
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
2D22
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CRYSTAL STRUCTURE OF COVALENT GLYCOSYL-ENZYME INTERMEDIATE OF CATALYTIC-SITE MUTANT XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86
Descriptor:ENDO-1,4-BETA-D-XYLANASE, XYLOPYRANOSE, SULFATE ION, ...
Authors:Suzuki, R., Kuno, A., Fujimoto, Z., Ito, S., Kawahara, S.I., Kaneko, S., Hasegawa, T., Taira, K.
Deposit date:2005-09-02
Release date:2006-10-10
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
2D23
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CRYSTAL STRUCTURE OF EP COMPLEX OF CATALYTIC-SITE MUTANT XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86
Descriptor:ENDO-1,4-BETA-D-XYLANASE, XYLOPYRANOSE, AZIDE ION, ...
Authors:Suzuki, R., Kuno, A., Fujimoto, Z., Ito, S., Kawahara, S.I., Kaneko, S., Hasegawa, T., Taira, K.
Deposit date:2005-09-02
Release date:2006-10-10
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
2D24
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CRYSTAL STRUCTURE OF ES COMPLEX OF CATALYTIC-SITE MUTANT XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86
Descriptor:ENDO-1,4-BETA-D-XYLANASE, XYLOPYRANOSE, SULFATE ION, ...
Authors:Suzuki, R., Kuno, A., Fujimoto, Z., Ito, S., Kawahara, S.I., Kaneko, S., Hasegawa, T., Taira, K.
Deposit date:2005-09-02
Release date:2006-10-10
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
5YFI
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CRYSTAL STRUCTURE OF THE ANTI-HUMAN PROSTAGLANDIN E RECEPTOR EP4 ANTIBODY FAB FRAGMENT
Descriptor:Light chain of Fab fragment, Heavy chain of Fab fragment, ZINC ION
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-21
Release date:2018-12-05
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YHL
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND AN ANTAGONIST BR-DERIVATIVE
Descriptor:Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-09-28
Release date:2018-12-05
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
5YWY
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CRYSTAL STRUCTURE OF THE HUMAN PROSTAGLANDIN E RECEPTOR EP4 IN COMPLEX WITH FAB AND ONO-AE3-208
Descriptor:Prostaglandin E2 receptor EP4 subtype,Prostaglandin E2 receptor EP4 subtype, Heavy chain of Fab fragment, Light chain of Fab fragment, ...
Authors:Toyoda, Y., Morimoto, K., Suno, R., Horita, S., Iwata, S., Kobayashi, T.
Deposit date:2017-11-30
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface.
Nat. Chem. Biol., 15, 2019
1ISV
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CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH XYLOSE
Descriptor:endo-1,4-beta-D-xylanase, BETA-D-XYLOPYRANOSE
Authors:Fujimoto, Z., Kuno, A., Kaneko, S., Kobayashi, H., Kusakabe, I., Mizuno, H.
Deposit date:2001-12-27
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
1ISW
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CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH XYLOBIOSE
Descriptor:endo-1,4-beta-D-xylanase, BETA-D-XYLOPYRANOSE
Authors:Fujimoto, Z., Kuno, A., Kaneko, S., Kobayashi, H., Kusakabe, I., Mizuno, H.
Deposit date:2001-12-27
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
1ISX
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CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH XYLOTRIOSE
Descriptor:endo-1,4-beta-D-xylanase, BETA-D-XYLOPYRANOSE
Authors:Fujimoto, Z., Kuno, A., Kaneko, S., Kobayashi, H., Kusakabe, I., Mizuno, H.
Deposit date:2001-12-27
Release date:2002-02-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
1ISY
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CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH GLUCOSE
Descriptor:endo-1,4-beta-D-xylanase, BETA-D-GLUCOSE
Authors:Fujimoto, Z., Kuno, A., Kaneko, S., Kobayashi, H., Kusakabe, I., Mizuno, H.
Deposit date:2001-12-27
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
1ISZ
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CRYSTAL STRUCTURE OF XYLANASE FROM STREPTOMYCES OLIVACEOVIRIDIS E-86 COMPLEXED WITH GALACTOSE
Descriptor:endo-1,4-beta-D-xylanase, BETA-D-GALACTOSE
Authors:Fujimoto, Z., Kuno, A., Kaneko, S., Kobayashi, H., Kusakabe, I., Mizuno, H.
Deposit date:2001-12-27
Release date:2002-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the sugar complexes of Streptomyces olivaceoviridis E-86 xylanase: sugar binding structure of the family 13 carbohydrate binding module.
J.Mol.Biol., 316, 2002
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