1YJ7
| Crystal structure of enteropathogenic E.coli (EPEC) type III secretion system protein EscJ | Descriptor: | GLYCEROL, PHOSPHATE ION, escJ | Authors: | Yip, C.K, Kimbrough, T.G, Felise, H.B, Vuckovic, M, Thomas, N.A, Pfuetzner, R.A, Frey, E.A, Finlay, B.B, Miller, S.I, Strynadka, N.C.J. | Deposit date: | 2005-01-13 | Release date: | 2005-06-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural characterization of the molecular platform for type III secretion system assembly. Nature, 435, 2005
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1XOU
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3GR5
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3GR1
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3GR0
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9B9G
| Structure of the PI4KA complex bound to Calcineurin | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, Hyccin, ... | Authors: | Shaw, A.L, Suresh, S, Yip, C.K, Burke, J.E. | Deposit date: | 2024-04-02 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A. Structure, 2024
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8DP0
| Structure of p110 gamma bound to the Ras inhibitory nanobody NB7 | Descriptor: | Nanobody NB7, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Authors: | Burke, J.E, Nam, S.E, Rathinaswamy, M.K, Yip, C.K. | Deposit date: | 2022-07-14 | Release date: | 2023-07-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Allosteric activation or inhibition of PI3K gamma mediated through conformational changes in the p110 gamma helical domain. Elife, 12, 2023
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8TGF
| Crystal structure of cEPG5 LIR/LGG-1 complex | Descriptor: | ACETATE ION, Ectopic P granules protein 5, Protein lgg-1 | Authors: | Cheung, Y.W.S, Yip, C.K. | Deposit date: | 2023-07-12 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Molecular basis of the mode of interaction between the tandem LC3-interacting region motif of the autophagy tethering factor EPG5 and ATG8 proteins To be published
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7MEZ
| Structure of the phosphoinositide 3-kinase p110 gamma (PIK3CG) p101 (PIK3R5) complex | Descriptor: | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphoinositide 3-kinase regulatory subunit 5 | Authors: | Burke, J.E, Dalwadi, U, Rathinaswamy, M.K, Yip, C.K. | Deposit date: | 2021-04-08 | Release date: | 2021-07-14 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of the phosphoinositide 3-kinase (PI3K) p110 gamma-p101 complex reveals molecular mechanism of GPCR activation. Sci Adv, 7, 2021
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7JHX
| Crystal structure of hEPG5 LIR/GABARAPL1 complex | Descriptor: | Ectopic P granules protein 5 homolog, Gamma-aminobutyric acid receptor-associated protein-like 1, SULFATE ION | Authors: | Cheung, Y.W.S, Yip, C.K. | Deposit date: | 2020-07-21 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Insights on autophagosome-lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5. Commun Biol, 4, 2021
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8AJ8
| Structure of p110 gamma bound to the p84 regulatory subunit | Descriptor: | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphoinositide 3-kinase regulatory subunit 6 | Authors: | Burke, J.E, Williams, R.L, Zhang, X. | Deposit date: | 2022-07-27 | Release date: | 2023-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (8.5 Å) | Cite: | Molecular basis for differential activation of p101 and p84 complexes of PI3K gamma by Ras and GPCRs. Cell Rep, 42, 2023
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4WJ2
| Mycobacterial protein | Descriptor: | Antigen MTB48 | Authors: | Solomonson, M, Strynadka, N.C.J. | Deposit date: | 2014-09-29 | Release date: | 2015-02-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of EspB from the ESX-1 type VII secretion system and insights into its export mechanism. Structure, 23, 2015
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4WJ1
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3N7N
| Structure of Csm1/Lrs4 complex | Descriptor: | Monopolin complex subunit CSM1, Monopolin complex subunit LRS4 | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-27 | Release date: | 2010-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3N4R
| Structure of Csm1 C-terminal domain, R3 form | Descriptor: | MALONATE ION, Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-22 | Release date: | 2010-09-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3N4X
| Structure of Csm1 full-length | Descriptor: | Monopolin complex subunit CSM1 | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-23 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.408 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3N4S
| Structure of Csm1 C-terminal domain, P21212 form | Descriptor: | Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-22 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3D1B
| Tetragonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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3D1D
| Hexagonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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3J83
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3K8P
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