Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8J6V
DownloadVisualize
BU of 8j6v by Molmil
Structure of yeast Arginyl-tRNA-protein transferase 1
Descriptor: arginyltransferase
Authors:Yashiro, Y, Tomita, K.
Deposit date:2023-04-26
Release date:2023-06-07
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of Arginyl-tRNA-protein transferase 1
To Be Published
7F36
DownloadVisualize
BU of 7f36 by Molmil
TacT complexed with acetyl-glycyl-tRNAGly
Descriptor: ACETYLAMINO-ACETIC ACID, CALCIUM ION, N-acetyltransferase domain-containing protein, ...
Authors:Yashiro, Y, Tomita, K.
Deposit date:2021-06-15
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Molecular basis of glycyl-tRNAGly acetylation by TacT from Salmonella Typhimurium
Cell Rep, 37, 2021
7F37
DownloadVisualize
BU of 7f37 by Molmil
Crystal structure of AtaT2-AtaR2 complex
Descriptor: DUF1778 domain-containing protein, GNAT family N-acetyltransferase
Authors:Yashiro, Y, Tomita, K.
Deposit date:2021-06-15
Release date:2021-12-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Molecular basis of glycyl-tRNAGly acetylation by TacT from Salmonella Typhimurium
Cell Rep, 37, 2021
7CHD
DownloadVisualize
BU of 7chd by Molmil
AtaT complexed with acetyl-methionyl-tRNAfMet
Descriptor: N-acetyltransferase domain-containing protein, RNA (77-MER)
Authors:Yashiro, Y, Tomita, K.
Deposit date:2020-07-05
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.804 Å)
Cite:Mechanism of aminoacyl-tRNA acetylation by an aminoacyl-tRNA acetyltransferase AtaT from enterohemorrhagic E. coli.
Nat Commun, 11, 2020
6AJN
DownloadVisualize
BU of 6ajn by Molmil
Crystal structure of AtaTR bound with AcCoA
Descriptor: ACETYL COENZYME *A, DUF1778 domain-containing protein, N-acetyltransferase
Authors:Yashiro, Y, Yamashita, S, Tomita, K.
Deposit date:2018-08-28
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal Structure of the Enterohemorrhagic Escherichia coli AtaT-AtaR Toxin-Antitoxin Complex.
Structure, 27, 2019
6AJM
DownloadVisualize
BU of 6ajm by Molmil
Crystal structure of apo AtaTR
Descriptor: DUF1778 domain-containing protein, N-acetyltransferase, TRIETHYLENE GLYCOL
Authors:Yashiro, Y, Yamashita, S, Tomita, K.
Deposit date:2018-08-28
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Crystal Structure of the Enterohemorrhagic Escherichia coli AtaT-AtaR Toxin-Antitoxin Complex.
Structure, 27, 2019
7BYY
DownloadVisualize
BU of 7byy by Molmil
Crystal structure of bacterial toxin
Descriptor: Acetyltransferase
Authors:Zhang, C, Yashiro, Y, Tomita, K.
Deposit date:2020-04-25
Release date:2020-06-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Substrate specificities of Escherichia coli ItaT that acetylates aminoacyl-tRNAs.
Nucleic Acids Res., 48, 2020
8XHR
DownloadVisualize
BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Authors:Liu, J, Yashiro, Y, Tomita, K.
Deposit date:2023-12-18
Release date:2024-02-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
7VMC
DownloadVisualize
BU of 7vmc by Molmil
Crystal structure of EF-Tu/CdiA/CdiI
Descriptor: Contact-dependent inhibitor I, Elongation factor Tu, tRNA nuclease CdiA
Authors:Wang, J, Yashiro, Y, Tomita, K.
Deposit date:2021-10-08
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.413 Å)
Cite:Mechanistic insights into tRNA cleavage by a contact-dependent growth inhibitor protein and translation factors.
Nucleic Acids Res., 50, 2022
8ZYC
DownloadVisualize
BU of 8zyc by Molmil
Cryo-EM structure of uropathogenic Escherichia coli CysK:CdiA:tRNA complex A
Descriptor: Cysteine synthase A, MAGNESIUM ION, tRNA nuclease CdiA, ...
Authors:Feng, Z, Yashiro, Y, Tomita, K.
Deposit date:2024-06-17
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Mechanism of activation of contact-dependent growth inhibition tRNase toxin by the amino acid biogenesis factor CysK in the bacterial competition system.
To Be Published
8ZYD
DownloadVisualize
BU of 8zyd by Molmil
Cryo-EM structure of uropathogenic Escherichia coli CysK:CdiA:tRNA complex B
Descriptor: Cysteine synthase A, MAGNESIUM ION, tRNA nuclease CdiA, ...
Authors:Feng, Z, Yashiro, Y, Tomita, K.
Deposit date:2024-06-17
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Mechanism of activation of contact-dependent growth inhibition tRNase toxin by the amino acid biogenesis factor CysK in the bacterial competition system.
To Be Published
8GU3
DownloadVisualize
BU of 8gu3 by Molmil
Crystal structure of Caenorhabditis elegans METT-10 methyltransferase domain
Descriptor: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
Authors:Ju, J, Tomita, K.
Deposit date:2022-09-09
Release date:2023-02-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis.
Nucleic Acids Res., 51, 2023
6KRO
DownloadVisualize
BU of 6kro by Molmil
Tankyrase-2 in complex with RK-582
Descriptor: 6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-fluoranyl-1-methyl-1'-(8-methyl-4-oxidanylidene-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-2-yl)spiro[indole-3,4'-piperidine]-2-one, GLYCEROL, PHOSPHATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2019-08-22
Release date:2020-04-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.
J.Med.Chem., 63, 2020
5ZQQ
DownloadVisualize
BU of 5zqq by Molmil
Tankyrase-2 in complex with compound 52
Descriptor: 1-methyl-1'-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)spiro[indole-3,4'-piperidin]-2(1H)-one, GLYCEROL, PHOSPHATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2018-04-19
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
5ZQO
DownloadVisualize
BU of 5zqo by Molmil
Tankyrase-2 in complex with compound 1a
Descriptor: 2-[4-(2-methoxyphenyl)piperazin-1-yl]-5,6,7,8-tetrahydroquinazolin-4(3H)-one, GLYCEROL, SULFATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2018-04-19
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
5ZQR
DownloadVisualize
BU of 5zqr by Molmil
Tankyrase-2 in complex with compound 40c
Descriptor: 2-[4,6-difluoro-1-(2-hydroxyethyl)-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl]-5,6,7,8-tetrahydroquinazolin-4(3H)-one, GLYCEROL, PHOSPHATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2018-04-19
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
6A84
DownloadVisualize
BU of 6a84 by Molmil
Tankyrase-2 in complex with compound 15d
Descriptor: 2-(4-chloro-1,2-dihydro-1'H-spiro[indole-3,4'-piperidin]-1'-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one, GLYCEROL, PHOSPHATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2018-07-06
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
5ZQP
DownloadVisualize
BU of 5zqp by Molmil
Tankyrase-2 in complex with compound 12
Descriptor: 1'-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)-2H-spiro[1-benzofuran-3,4'-piperidin]-2-one, GLYCEROL, PHOSPHATE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T.
Deposit date:2018-04-19
Release date:2019-04-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon