Author results

4GJP
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CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO DSDNA CONTAINING REPETITIVE METHYL-CPG
分子名称:Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), ...
著者Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G.
登録日2012-08-10
公開日2012-10-03
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of a protein complex
To be Published
4GJR
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CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO METHYLATED DSDNA
分子名称:Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P*CP*TP*CP*(5CM)P*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3')
著者Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G.
登録日2012-08-10
公開日2012-10-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of a protein complex
To be Published
1SDZ
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A REAPER PEPTIDE
分子名称:Apoptosis 1 inhibitor, Reaper, ZINC ION
著者Yan, N., Wu, J.W., Shi, Y.
登録日2004-02-15
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
1SE0
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A GRIM PEPTIDE
分子名称:Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION
著者Yan, N., Wu, J.W., Shi, Y.
登録日2004-02-15
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
1TY4
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CRYSTAL STRUCTURE OF A CED-9/EGL-1 COMPLEX
分子名称:Apoptosis regulator ced-9, EGg Laying defective EGL-1, programmed cell death activator
著者Yan, N., Gu, L., Kokel, D., Xue, D., Shi, Y.
登録日2004-07-07
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4
Mol.Cell, 15, 2004
2A5Y
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STRUCTURE OF A CED-4/CED-9 COMPLEX
分子名称:Apoptosis regulator ced-9, ced-4, MAGNESIUM ION, ...
著者Yan, N., Liu, Q., Hao, Q., Gu, L., Shi, Y.
登録日2005-07-01
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
Nature, 437, 2005
2FP3
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CRYSTAL STRUCTURE OF THE DROSOPHILA INITIATOR CASPASE DRONC
分子名称:Caspase Nc
著者Yan, N., Gu, L., Shi, Y.
登録日2006-01-15
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and activation mechanism of the Drosophila initiator caspase dronc
J.Biol.Chem., 281, 2006
4GC0
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THE STRUCTURE OF THE MFS (MAJOR FACILITATOR SUPERFAMILY) PROTON:XYLOSE SYMPORTER XYLE BOUND TO 6-BROMO-6-DEOXY-D-GLUCOSE
分子名称:D-xylose-proton symporter, 6-bromo-6-deoxy-beta-D-glucopyranose, nonyl beta-D-glucopyranoside
著者Yan, N., Sun, L.F., Zeng, X., Yan, C.Y.
登録日2012-07-28
公開日2012-10-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
3NEF
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HIGH-RESOLUTION PYRABACTIN-BOUND PYL1 STRUCTURE
分子名称:Abscisic acid receptor PYL1, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
著者Yan, N.
登録日2010-06-08
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional mechanism of the ABA agonist pyrabactin
J.Biol.Chem., 285, 2010
3NEG
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PYRABACTIN-BOUND PYL1 STRUCTURE IN THE OPEN AND CLOSE FORMS
分子名称:Abscisic acid receptor PYL1, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, BROMIDE ION
著者Yan, N.
登録日2010-06-08
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Functional mechanism of the ABA agonist pyrabactin
J.Biol.Chem., 285, 2010
3NR4
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PYRABACTIN-BOUND PYL2
分子名称:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
著者Yan, N.
登録日2010-06-30
公開日2010-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Single amino acid alteration between Valine and Isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2
J.Biol.Chem., 285, 2010
6P2J
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DIMERIC STRUCTURE OF ACAT1
分子名称:Sterol O-acyltransferase 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)
著者Yan, N., Qian, H.W.
登録日2019-05-21
公開日2020-05-20
最終更新日2020-06-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for catalysis and substrate specificity of human ACAT1.
Nature, 581, 2020
6P2P
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TETRAMERIC STRUCTURE OF ACAT1
分子名称:Sterol O-acyltransferase 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name)
著者Yan, N., Qian, H.W.
登録日2019-05-21
公開日2020-05-20
最終更新日2020-06-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for catalysis and substrate specificity of human ACAT1.
Nature, 581, 2020
6DMB
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CRYO-EM STRUCTURE OF HUMAN PTCH1
分子名称:Protein patched homolog 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-04
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMO
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CRYO-EM STRUCTURE OF HUMAN PTCH1 WITH THREE MUTATIONS L282Q/T500F/P504L
分子名称:Protein patched homolog 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMY
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CRYO-EM STRUCTURE OF HUMAN PTCH1 AND SHHN COMPLEX
分子名称:Protein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6KZO
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MEMBRANE PROTEIN
分子名称:Voltage-dependent T-type calcium channel subunit alpha-1G, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N.
登録日2019-09-25
公開日2019-12-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of apo and antagonist-bound human Cav3.1.
Nature, 576, 2019
6KZP
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CALCIUM CHANNEL-LIGAND
分子名称:Voltage-dependent T-type calcium channel subunit alpha-1G,Voltage-dependent T-type calcium channel subunit alpha-1G, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N.
登録日2019-09-25
公開日2019-12-18
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of apo and antagonist-bound human Cav3.1.
Nature, 576, 2019
6N7G
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CRYO-EM STRUCTURE OF TETRAMERIC PTCH1 IN COMPLEX WITH SHHNP (FORM I)
分子名称:Protein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Nat Commun, 10, 2019
6N7H
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CRYO-EM STRUCTURE OF THE 2:1 HPTCH1-SHHP COMPLEX
分子名称:Protein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Nat Commun, 10, 2019
6N7K
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CRYO-EM STRUCTURE OF TETRAMERIC PTCH1 IN COMPLEX WITH SHHNP (FORM II)
分子名称:Protein patched homolog 1, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Nat Commun, 10, 2019
6VWX
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NACHBAC IN LIPID NANODISC
分子名称:BH1501 protein, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION
著者Yan, N., Gao, S.
登録日2020-02-20
公開日2020-06-24
最終更新日2020-07-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VX3
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NACHBAC IN GDN
分子名称:BH1501 protein, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
著者Yan, N., Gao, S.
登録日2020-02-21
公開日2020-06-24
最終更新日2020-07-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VXO
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NACHBAC-NAV1.7VSDII CHIMERA IN NANODISC
分子名称:NaChBac-Nav1.7VSDII chimera, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
著者Yan, N., Gao, S.
登録日2020-02-22
公開日2020-06-24
最終更新日2020-07-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W5R
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NPC1 STRUCTURE IN NANODISC
分子名称:NPC intracellular cholesterol transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N., Qian, H.W., Wu, X.L.
登録日2020-03-13
公開日2020-06-17
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2.
Cell, 182, 2020
167132
件を2020-07-29に公開中