4GJP | | CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO DSDNA CONTAINING REPETITIVE METHYL-CPG | | 分子名称: | Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), ... | | 著者 | Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G. | | 登録日 | 2012-08-10 | | 公開日 | 2012-10-03 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal structure of a protein complex
To be Published
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4GJR | | CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO METHYLATED DSDNA | | 分子名称: | Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P*CP*TP*CP*(5CM)P*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3') | | 著者 | Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G. | | 登録日 | 2012-08-10 | | 公開日 | 2012-10-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of a protein complex
To be Published
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1SDZ | | CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A REAPER PEPTIDE | | 分子名称: | Apoptosis 1 inhibitor, Reaper, ZINC ION | | 著者 | Yan, N., Wu, J.W., Shi, Y. | | 登録日 | 2004-02-15 | | 公開日 | 2004-04-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
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1SE0 | | CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A GRIM PEPTIDE | | 分子名称: | Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION | | 著者 | Yan, N., Wu, J.W., Shi, Y. | | 登録日 | 2004-02-15 | | 公開日 | 2004-04-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
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1TY4 | | CRYSTAL STRUCTURE OF A CED-9/EGL-1 COMPLEX | | 分子名称: | Apoptosis regulator ced-9, EGg Laying defective EGL-1, programmed cell death activator | | 著者 | Yan, N., Gu, L., Kokel, D., Xue, D., Shi, Y. | | 登録日 | 2004-07-07 | | 公開日 | 2004-09-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4
Mol.Cell, 15, 2004
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2A5Y | | STRUCTURE OF A CED-4/CED-9 COMPLEX | | 分子名称: | Apoptosis regulator ced-9, ced-4, MAGNESIUM ION, ... | | 著者 | Yan, N., Liu, Q., Hao, Q., Gu, L., Shi, Y. | | 登録日 | 2005-07-01 | | 公開日 | 2005-10-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
Nature, 437, 2005
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2FP3 | |
6N7G | |
6N7K | |
4GC0 | | THE STRUCTURE OF THE MFS (MAJOR FACILITATOR SUPERFAMILY) PROTON:XYLOSE SYMPORTER XYLE BOUND TO 6-BROMO-6-DEOXY-D-GLUCOSE | | 分子名称: | D-xylose-proton symporter, 6-bromo-6-deoxy-beta-D-glucopyranose, B-NONYLGLUCOSIDE | | 著者 | Yan, N., Sun, L.F., Zeng, X., Yan, C.Y. | | 登録日 | 2012-07-28 | | 公開日 | 2012-10-17 | | 最終更新日 | 2012-10-31 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
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3NEF | | HIGH-RESOLUTION PYRABACTIN-BOUND PYL1 STRUCTURE | | 分子名称: | Abscisic acid receptor PYL1, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide | | 著者 | Yan, N. | | 登録日 | 2010-06-08 | | 公開日 | 2010-06-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Functional mechanism of the ABA agonist pyrabactin
J.Biol.Chem., 285, 2010
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3NEG | |
3NR4 | | PYRABACTIN-BOUND PYL2 | | 分子名称: | Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide | | 著者 | Yan, N. | | 登録日 | 2010-06-30 | | 公開日 | 2010-07-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Single amino acid alteration between Valine and Isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2
J.Biol.Chem., 285, 2010
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6DMB | | CRYO-EM STRUCTURE OF HUMAN PTCH1 | | 分子名称: | Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE | | 著者 | Yan, N., Gong, X., Qian, H.W. | | 登録日 | 2018-06-04 | | 公開日 | 2018-07-11 | | 最終更新日 | 2018-08-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
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6DMO | |
6DMY | | CRYO-EM STRUCTURE OF HUMAN PTCH1 AND SHHN COMPLEX | | 分子名称: | Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ... | | 著者 | Yan, N., Gong, X., Qian, H.W. | | 登録日 | 2018-06-05 | | 公開日 | 2018-07-11 | | 最終更新日 | 2018-08-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
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6N7H | | CRYO-EM STRUCTURE OF THE 2:1 HPTCH1-SHHP COMPLEX | | 分子名称: | Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ... | | 著者 | Yan, N., Gong, X., Qian, H.W. | | 登録日 | 2018-11-27 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Nat Commun, 10, 2019
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3J8H | | STRUCTURE OF THE RABBIT RYANODINE RECEPTOR RYR1 IN COMPLEX WITH FKBP12 AT 3.8 ANGSTROM RESOLUTION | | 分子名称: | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION | | 著者 | Yan, Z., Bai, X., Yan, C., Wu, J., Scheres, S.H.W., Shi, Y., Yan, N. | | 登録日 | 2014-10-26 | | 公開日 | 2014-12-10 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
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3JBR | | CRYO-EM STRUCTURE OF THE RABBIT VOLTAGE-GATED CALCIUM CHANNEL CAV1.1 COMPLEX AT 4.2 ANGSTROM | | 分子名称: | Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent calcium channel gamma-1 subunit, ... | | 著者 | Wu, J.P., Yan, Z., Yan, N. | | 登録日 | 2015-09-29 | | 公開日 | 2015-12-30 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of the voltage-gated calcium channel Cav1.1 complex
Science, 350, 2015
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3RT0 | | CRYSTAL STRUCTURE OF PYL10-HAB1 COMPLEX IN THE ABSENCE OF ABSCISIC ACID (ABA) | | 分子名称: | Protein phosphatase 2C 16, Abscisic acid receptor PYL10, MAGNESIUM ION | | 著者 | Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N. | | 登録日 | 2011-05-02 | | 公開日 | 2011-06-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.113 Å) | | 主引用文献 | The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
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3RT2 | | CRYSTAL STRUCTURE OF APO-PYL10 | | 分子名称: | Abscisic acid receptor PYL10 | | 著者 | Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N. | | 登録日 | 2011-05-02 | | 公開日 | 2011-06-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
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4XU4 | | CRYSTAL STRUCTURE OF A MYCOBACTERIAL INSIG HOMOLOG MVINS FROM MYCOBACTERIUM VANBAALENII AT 1.9A RESOLUTION | | 分子名称: | Uncharacterized protein, B-NONYLGLUCOSIDE, DECYLAMINE-N,N-DIMETHYL-N-OXIDE | | 著者 | Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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4XU5 | | CRYSTAL STRUCTURE OF MVINS BOUND TO A BROMINE-DERIVED 14C DIACYLGLYCEROL (DAG) AT 2.1A RESOLUTION | | 分子名称: | Uncharacterized protein, (2S)-1-[(13-bromotridecanoyl)oxy]-3-hydroxypropan-2-yl tetradecanoate, DECANE, ... | | 著者 | Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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4XU6 | | CRYSTAL STRUCTURE OF CROSS-LINKED MVINS R77C TRIMER AT 1.9A RESOLUTION | | 分子名称: | Uncharacterized protein, B-OCTYLGLUCOSIDE, N-TRIDECANOIC ACID | | 著者 | Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N. | | 登録日 | 2015-01-25 | | 公開日 | 2015-10-14 | | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | | 主引用文献 | PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
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2NRF | | CRYSTAL STRUCTURE OF GLPG, A RHOMBOID FAMILY INTRAMEMBRANE PROTEASE | | 分子名称: | Protein GlpG | | 著者 | Wu, Z., Yan, N., Feng, L., Yan, H., Gu, L., Shi, Y. | | 登録日 | 2006-11-02 | | 公開日 | 2006-11-14 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006
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