Author results

4GJP
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CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO DSDNA CONTAINING REPETITIVE METHYL-CPG
分子名称:Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), ...
著者Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G.
登録日2012-08-10
公開日2012-10-03
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of a protein complex
To be Published
4GJR
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CRYSTAL STRUCTURE OF THE TAL EFFECTOR DHAX3 BOUND TO METHYLATED DSDNA
分子名称:Hax3, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*(5CM)P*TP*AP*(5CM)P*CP*TP*CP*(5CM)P*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*AP*GP*AP*GP*GP*GP*AP*CP*A)-3')
著者Yan, N., Deng, D., Yan, C.Y., Yin, P., Pan, X.J., Shi, Y.G.
登録日2012-08-10
公開日2012-10-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of a protein complex
To be Published
1SDZ
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A REAPER PEPTIDE
分子名称:Apoptosis 1 inhibitor, Reaper, ZINC ION
著者Yan, N., Wu, J.W., Shi, Y.
登録日2004-02-15
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
1SE0
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CRYSTAL STRUCTURE OF DIAP1 BIR1 BOUND TO A GRIM PEPTIDE
分子名称:Apoptosis 1 inhibitor, Cell death protein Grim, ZINC ION
著者Yan, N., Wu, J.W., Shi, Y.
登録日2004-02-15
公開日2004-04-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.
Nat.Struct.Mol.Biol., 11, 2004
1TY4
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CRYSTAL STRUCTURE OF A CED-9/EGL-1 COMPLEX
分子名称:Apoptosis regulator ced-9, EGg Laying defective EGL-1, programmed cell death activator
著者Yan, N., Gu, L., Kokel, D., Xue, D., Shi, Y.
登録日2004-07-07
公開日2004-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4
Mol.Cell, 15, 2004
2A5Y
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STRUCTURE OF A CED-4/CED-9 COMPLEX
分子名称:Apoptosis regulator ced-9, ced-4, MAGNESIUM ION, ...
著者Yan, N., Liu, Q., Hao, Q., Gu, L., Shi, Y.
登録日2005-07-01
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
Nature, 437, 2005
2FP3
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CRYSTAL STRUCTURE OF THE DROSOPHILA INITIATOR CASPASE DRONC
分子名称:Caspase Nc
著者Yan, N., Gu, L., Shi, Y.
登録日2006-01-15
公開日2006-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and activation mechanism of the Drosophila initiator caspase dronc
J.Biol.Chem., 281, 2006
6N7G
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CRYO-EM STRUCTURE OF TETRAMERIC PTCH1 IN COMPLEX WITH SHHNP (FORM I)
分子名称:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Cryo-EM structure of the 2:1 hPtch1-Shhp complex
To Be Published
6N7K
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CRYO-EM STRUCTURE OF TETRAMERIC PTCH1 IN COMPLEX WITH SHHNP (FORM II)
分子名称:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Cryo-EM structure of the 2:1 hPtch1-Shhp complex
To Be Published
4GC0
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THE STRUCTURE OF THE MFS (MAJOR FACILITATOR SUPERFAMILY) PROTON:XYLOSE SYMPORTER XYLE BOUND TO 6-BROMO-6-DEOXY-D-GLUCOSE
分子名称:D-xylose-proton symporter, 6-bromo-6-deoxy-beta-D-glucopyranose, B-NONYLGLUCOSIDE
著者Yan, N., Sun, L.F., Zeng, X., Yan, C.Y.
登録日2012-07-28
公開日2012-10-17
最終更新日2012-10-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
Nature, 490, 2012
3NEF
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HIGH-RESOLUTION PYRABACTIN-BOUND PYL1 STRUCTURE
分子名称:Abscisic acid receptor PYL1, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
著者Yan, N.
登録日2010-06-08
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional mechanism of the ABA agonist pyrabactin
J.Biol.Chem., 285, 2010
3NEG
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PYRABACTIN-BOUND PYL1 STRUCTURE IN THE OPEN AND CLOSE FORMS
分子名称:Abscisic acid receptor PYL1, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, BROMIDE ION
著者Yan, N.
登録日2010-06-08
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Functional mechanism of the ABA agonist pyrabactin
J.Biol.Chem., 285, 2010
3NR4
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PYRABACTIN-BOUND PYL2
分子名称:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
著者Yan, N.
登録日2010-06-30
公開日2010-07-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Single amino acid alteration between Valine and Isoleucine determines the distinct pyrabactin selectivity by PYL1 and PYL2
J.Biol.Chem., 285, 2010
6DMB
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CRYO-EM STRUCTURE OF HUMAN PTCH1
分子名称:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE, CHOLESTEROL HEMISUCCINATE
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-04
公開日2018-07-11
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMO
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CRYO-EM STRUCTURE OF HUMAN PTCH1 WITH THREE MUTATIONS L282Q/T500F/P504L
分子名称:Protein patched homolog 1, N-ACETYL-D-GLUCOSAMINE
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6DMY
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CRYO-EM STRUCTURE OF HUMAN PTCH1 AND SHHN COMPLEX
分子名称:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-06-05
公開日2018-07-11
最終更新日2018-08-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for the recognition of Sonic Hedgehog by human Patched1.
Science, 361, 2018
6N7H
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CRYO-EM STRUCTURE OF THE 2:1 HPTCH1-SHHP COMPLEX
分子名称:Protein patched homolog 1, Sonic hedgehog protein, N-ACETYL-D-GLUCOSAMINE, ...
著者Yan, N., Gong, X., Qian, H.W.
登録日2018-11-27
公開日2019-05-29
最終更新日2019-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm.
Nat Commun, 10, 2019
3J8H
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STRUCTURE OF THE RABBIT RYANODINE RECEPTOR RYR1 IN COMPLEX WITH FKBP12 AT 3.8 ANGSTROM RESOLUTION
分子名称:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
著者Yan, Z., Bai, X., Yan, C., Wu, J., Scheres, S.H.W., Shi, Y., Yan, N.
登録日2014-10-26
公開日2014-12-10
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
3JBR
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CRYO-EM STRUCTURE OF THE RABBIT VOLTAGE-GATED CALCIUM CHANNEL CAV1.1 COMPLEX AT 4.2 ANGSTROM
分子名称:Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent calcium channel gamma-1 subunit, ...
著者Wu, J.P., Yan, Z., Yan, N.
登録日2015-09-29
公開日2015-12-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the voltage-gated calcium channel Cav1.1 complex
Science, 350, 2015
3RT0
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CRYSTAL STRUCTURE OF PYL10-HAB1 COMPLEX IN THE ABSENCE OF ABSCISIC ACID (ABA)
分子名称:Protein phosphatase 2C 16, Abscisic acid receptor PYL10, MAGNESIUM ION
著者Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N.
登録日2011-05-02
公開日2011-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.113 Å)
主引用文献The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
3RT2
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CRYSTAL STRUCTURE OF APO-PYL10
分子名称:Abscisic acid receptor PYL10
著者Hao, Q., Yin, P., Li, W., Wang, L., Yan, C., Wang, J., Yan, N.
登録日2011-05-02
公開日2011-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Molecular Basis of ABA-Independent Inhibition of PP2Cs by a Subclass of PYL Proteins
Mol.Cell, 42, 2011
4XU4
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CRYSTAL STRUCTURE OF A MYCOBACTERIAL INSIG HOMOLOG MVINS FROM MYCOBACTERIUM VANBAALENII AT 1.9A RESOLUTION
分子名称:Uncharacterized protein, B-NONYLGLUCOSIDE, DECYLAMINE-N,N-DIMETHYL-N-OXIDE
著者Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N.
登録日2015-01-25
公開日2015-10-14
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
4XU5
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CRYSTAL STRUCTURE OF MVINS BOUND TO A BROMINE-DERIVED 14C DIACYLGLYCEROL (DAG) AT 2.1A RESOLUTION
分子名称:Uncharacterized protein, (2S)-1-[(13-bromotridecanoyl)oxy]-3-hydroxypropan-2-yl tetradecanoate, DECANE, ...
著者Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N.
登録日2015-01-25
公開日2015-10-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
4XU6
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CRYSTAL STRUCTURE OF CROSS-LINKED MVINS R77C TRIMER AT 1.9A RESOLUTION
分子名称:Uncharacterized protein, B-OCTYLGLUCOSIDE, N-TRIDECANOIC ACID
著者Ren, R.B., Wu, J.P., Yan, C.Y., He, Y., Yan, N.
登録日2015-01-25
公開日2015-10-14
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels
Science, 349, 2015
2NRF
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CRYSTAL STRUCTURE OF GLPG, A RHOMBOID FAMILY INTRAMEMBRANE PROTEASE
分子名称:Protein GlpG
著者Wu, Z., Yan, N., Feng, L., Yan, H., Gu, L., Shi, Y.
登録日2006-11-02
公開日2006-11-14
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006