3X2Q

X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 angstrom resolution

Summary for 3X2Q

• Entry DOI: 10.2210/pdb3x2q/pdb
• Descriptor: Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 7A1, mitochondrial, Cytochrome c oxidase subunit 7B, mitochondrial, ... (29 entities in total)
• Functional Keywords: oxidoreductase, respiratory chain, electron transport, heme, iron, mitochondorial inner membrane
• Biological source: Bos taurus (domestic cattle); More
• Total number of polymer chains: 26
• Total formula weight: 441958.89

Authors

Yano, N.,Muramoto, K.,Mochizuki, M.,Shinzawa-Itoh, K.,Yamashita, E.,Yoshikawa, S.,Tsukihara, T. (deposition date: 2014-12-26, release date: 2015-06-10, Last modification date: 2024-12-25)

Primary citation

Yano, N.,Muramoto, K.,Mochizuki, M.,Shinzawa-Itoh, K.,Yamashita, E.,Yoshikawa, S.,Tsukihara, T.
X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 angstrom resolution.
Acta Crystallogr F Struct Biol Commun, 71:726-730, 2015

PubMed Abstract: The X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state was determined at 2.0 Å resolution. The structure reveals that the peroxide that bridges the two metals in the fully oxidized state is replaced by a cyanide ion bound in a nearly symmetric end-on fashion without significantly changing the protein conformation outside the two metal sites.

PubMed: 26057802
DOI: 10.1107/S2053230X15007025

Experimental method

X-RAY DIFFRACTION (2 Å)