3X2Q
X-ray structure of cyanide-bound bovine heart cytochrome c oxidase in the fully oxidized state at 2.0 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N | Cytochrome c oxidase subunit 1 | polymer | 514 | 57093.9 | 2 | UniProt (P00396) Pfam (PF00115) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide I |
| 2 | B, O | Cytochrome c oxidase subunit 2 | polymer | 227 | 26068.4 | 2 | UniProt (P68530) Pfam (PF02790) Pfam (PF00116) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide II |
| 3 | C, P | Cytochrome c oxidase subunit 3 | polymer | 261 | 29957.6 | 2 | UniProt (P00415) Pfam (PF00510) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide III |
| 4 | D, Q | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | polymer | 147 | 17179.6 | 2 | UniProt (P00423) Pfam (PF02936) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1 |
| 5 | E, R | Cytochrome c oxidase subunit 5A, mitochondrial | polymer | 109 | 12453.1 | 2 | UniProt (P00426) Pfam (PF02284) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide Va |
| 6 | F, S | Cytochrome c oxidase subunit 5B, mitochondrial | polymer | 98 | 10684.0 | 2 | UniProt (P00428) Pfam (PF01215) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIa, Cytochrome c oxidase polypeptide Vb |
| 7 | G, T | Cytochrome c oxidase subunit 6A2, mitochondrial | polymer | 85 | 9629.8 | 2 | UniProt (P07471) Pfam (PF02046) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIa-heart, COXVIAH, Cytochrome c oxidase polypeptide VIb |
| 8 | H, U | Cytochrome c oxidase subunit 6B1 | polymer | 85 | 10039.2 | 2 | UniProt (P00429) Pfam (PF02297) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VII, Cytochrome c oxidase subunit AED, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1 |
| 9 | I, V | Cytochrome c oxidase subunit 6C | polymer | 73 | 8537.0 | 2 | UniProt (P04038) Pfam (PF02937) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIc, Cytochrome c oxidase subunit STA |
| 10 | J, W | Cytochrome c oxidase subunit 7A1, mitochondrial | polymer | 59 | 6682.7 | 2 | UniProt (P07470) Pfam (PF02238) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase subunit VIIIc, VIIIC, Cytochrome c oxidase subunit VIIa-heart, Cytochrome c oxidase subunit VIIa-H, Cytochrome c oxidase subunit VIIa-muscle, Cytochrome c oxidase subunit VIIa-M |
| 11 | K, X | Cytochrome c oxidase subunit 7B, mitochondrial | polymer | 56 | 6365.2 | 2 | UniProt (P13183) Pfam (PF05392) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIIb, IHQ |
| 12 | L, Y | Cytochrome c oxidase subunit 7C, mitochondrial | polymer | 47 | 5449.4 | 2 | UniProt (P00430) Pfam (PF02935) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIIIA, Cytochrome c oxidase polypeptide VIIc |
| 13 | M, Z | Cytochrome c oxidase subunit 8B, mitochondrial | polymer | 46 | 4967.8 | 2 | UniProt (P10175) Pfam (PF02285) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Cytochrome c oxidase polypeptide VIII-heart, Cytochrome c oxidase subunit 8-1, Cytochrome c oxidase subunit 8H, IX, VIIIb |
| 14 | A, N | CYANIDE ION | non-polymer | 26.0 | 2 | Chemie (CYN) | |||
| 15 | A, N | HEME-A | non-polymer | 852.8 | 4 | Chemie (HEA) | |||
| 16 | A, N | COPPER (II) ION | non-polymer | 63.5 | 2 | Chemie (CU) | |||
| 17 | A, N | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 18 | A, N | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 19 | A, N, D, Q, L | TRISTEAROYLGLYCEROL | non-polymer | 891.5 | 6 | Chemie (TGL) | |||
| 20 | A, N, C, P | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE | non-polymer | 749.0 | 8 | Chemie (PGV) | |||
| 21 | B, O | DINUCLEAR COPPER ION | non-polymer | 127.1 | 2 | Chemie (CUA) | |||
| 22 | B, O, C, P | CHOLIC ACID | non-polymer | 408.6 | 6 | Chemie (CHD) | |||
| 23 | C, P | UNKNOWN ATOM OR ION | non-polymer | 2 | Chemie (UNX) | ||||
| 24 | T, C, P, G | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) | |||
| 25 | C, P, G, T | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE | non-polymer | 768.1 | 6 | Chemie (PEK) | |||
| 26 | O, E | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE | non-polymer | 759.1 | 2 | Chemie (PSC) | |||
| 27 | F, S | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 28 | M, Z, P, G | DECYL-BETA-D-MALTOPYRANOSIDE | non-polymer | 482.6 | 4 | Chemie (DMU) | |||
| 29 | water | water | 18.0 | 1286 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 26 |
| Total formula weight | 410215.6 | |
| Non-Polymers* | Number of molecules | 54 |
| Total formula weight | 31775.3 | |
| All* | Total formula weight | 441990.9 |
