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6GYP
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CRYO-EM STRUCTURE OF THE CBF3-CORE-NDC10-DBD COMPLEX OF THE BUDDING YEAST KINETOCHORE
Descriptor:Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1, ...
Authors:Yan, K., Zhang, Z., Yang, J., McLaughlin, S.H., Barford, D.
Deposit date:2018-07-01
Release date:2018-12-05
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
6GYS
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CRYO-EM STRUCTURE OF THE CBF3-CEN3 COMPLEX OF THE BUDDING YEAST KINETOCHORE
Descriptor:Centromere DNA-binding protein complex CBF3 subunit C, Centromere DNA-binding protein complex CBF3 subunit B, Suppressor of kinetochore protein 1, ...
Authors:Yan, K., Zhang, Z., Yang, J., McLaughlin, S.H., Barford, D.
Deposit date:2018-07-01
Release date:2018-12-05
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
6GYU
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CRYO-EM STRUCTURE OF THE CBF3-MSK COMPLEX OF THE BUDDING YEAST KINETOCHORE
Descriptor:Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1, ...
Authors:Yan, K., Zhang, Z., Yang, J., McLaughlin, S.H., Barford, D.
Deposit date:2018-07-02
Release date:2018-12-05
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
Nat. Struct. Mol. Biol., 25, 2018
2L5C
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SOLUTION STRUCTURES OF HUMAN PIWI-LIKE 1 PAZ DOMAIN
Descriptor:Piwi-like protein 1
Authors:Zeng, L., Zhang, Q., Yan, K., Zhou, M.
Deposit date:2010-10-29
Release date:2011-04-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
2L5D
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SOLUTION STRUCTURES OF HUMAN PIWI-LIKE 1 PAZ DOMAIN WITH SSRNA (5'-PUGACA)
Descriptor:Piwi-like protein 1, 5'-R(*UP*GP*AP*CP*A)-3'
Authors:Zeng, L., Zhang, Q., Yan, K., Zhou, M.
Deposit date:2010-10-29
Release date:2011-04-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insights into piRNA recognition by the human PIWI-like 1 PAZ domain.
Proteins, 79, 2011
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
Descriptor:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
Authors:Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
Deposit date:2014-10-24
Release date:2014-11-26
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
3JCD
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STRUCTURE OF ESCHERICHIA COLI EF4 IN POSTTRANSLOCATIONAL RIBOSOMES (POST EF4)
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Zhang, D., Yan, K., Liu, G., Song, G., Luo, J., Shi, Y., Cheng, E., Wu, S., Jiang, T., Low, J., Gao, N., Qin, Y.
Deposit date:2015-12-01
Release date:2016-01-13
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
3JCE
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STRUCTURE OF ESCHERICHIA COLI EF4 IN PRETRANSLOCATIONAL RIBOSOMES (PRE EF4)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Zhang, D., Yan, K., Liu, G., Song, G., Luo, J., Shi, Y., Cheng, E., Wu, S., Jiang, T., Low, J., Gao, N., Qin, Y.
Deposit date:2015-12-01
Release date:2016-01-13
Last modified:2017-02-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
5H4P
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STRUCTURAL SNAPSHOT OF CYTOPLASMIC PRE-60S RIBOSOMAL PARTICLES BOUND WITH NMD3, LSG1, TIF6 AND REH1
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Ma, C., Wu, S., Li, N., Chen, Y., Yan, K., Li, Z., Zheng, L., Lei, J., Woolford, J.L., Gao, N.
Deposit date:2016-11-01
Release date:2017-01-25
Last modified:2017-06-14
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
3JBU
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MECHANISMS OF RIBOSOME STALLING BY SECM AT MULTIPLE ELONGATION STEPS
Descriptor:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Zhang, J., Pan, X.J., Yan, K.G., Sun, S., Gao, N., Sui, S.F.
Deposit date:2015-10-16
Release date:2016-01-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
3JBV
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MECHANISMS OF RIBOSOME STALLING BY SECM AT MULTIPLE ELONGATION STEPS
Descriptor:RNA (1530-MER), 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Zhang, J., Pan, X.J., Yan, K.G., Sun, S., Gao, N., Sui, S.F.
Deposit date:2015-10-16
Release date:2016-01-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
3JCT
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CRYO-EM STRUCTURE OF EUKARYOTIC PRE-60S RIBOSOMAL SUBUNITS
Descriptor:60S ribosomal protein L2-A, 60S ribosomal protein L3, 60S ribosomal protein L4-A, ...
Authors:Wu, S., Kumcuoglu, B., Yan, K.G., Brown, H., Zhang, Y.X., Tan, D., Gamalinda, M., Yuan, Y., Li, Z.F., Jakovljevic, J., Ma, C.Y., Lei, J.L., Dong, M.Q., Woolford Jr., J.L., Gao, N.
Deposit date:2016-03-09
Release date:2016-06-01
Last modified:2017-02-01
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
5ERC
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X-RAY CRYSTAL STRUCTURE OF BRPF1 PZP DOMAIN
Descriptor:Peregrin, ZINC ION, CALCIUM ION
Authors:Klein, B.J., Andrews, F.H., Kutateladze, T.G.
Deposit date:2015-11-13
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Nucleic Acids Res., 44, 2016
5UK8
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THE CO-STRUCTURE OF (R)-4-(6-(1-(CYCLOPROPYLSULFONYL)CYCLOPROPYL)-2-(1H-INDOL-4-YL)PYRIMIDIN-4-YL)-3-METHYLMORPHOLINE AND A RATIONALLY DESIGNED PI3K-ALPHA MUTANT THAT MIMICS ATR
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, (R)-4-(6-(1-(cyclopropylsulfonyl)cyclopropyl)-2-(1H-indol-4-yl)pyrimidin-4-yl)-3-methylmorpholine
Authors:Knapp, M.S., Mamo, M., Elling, R.A.
Deposit date:2017-01-20
Release date:2017-06-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rationally Designed PI3K alpha Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.
J. Mol. Biol., 429, 2017
5UKJ
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THE CO-STRUCTURE OF N,N-DIMETHYL-4-[(6R)-6-METHYL-5-(1H-PYRROLO[2,3- B]PYRIDIN-4-YL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5- A]PYRAZIN-3-YL]BENZENESULFONAMIDE AND A RATIONALLY DESIGNED PI3K-ALPHA MUTANT THAT MIMICS ATR
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide
Authors:Knapp, M.S., Elling, R.A., Mamo, M.
Deposit date:2017-01-23
Release date:2017-05-10
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rationally Designed PI3K alpha Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.
J. Mol. Biol., 429, 2017
5UL1
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THE CO-STRUCTURE OF 3-AMINO-6-(4-((1-(DIMETHYLAMINO)PROPAN-2-YL)SULFONYL)PHENYL)-N-PHENYLPYRAZINE-2-CARBOXAMIDE AND A RATIONALLY DESIGNED PI3K-ALPHA MUTANT THAT MIMICS ATR
Descriptor:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha, 3-amino-6-(4-{[(2S)-1-(dimethylamino)propan-2-yl]sulfonyl}phenyl)-N-phenylpyrazine-2-carboxamide
Authors:Knapp, M.S., Elling, R.A., Mamo, M.
Deposit date:2017-01-23
Release date:2017-05-10
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Rationally Designed PI3K alpha Mutants to Mimic ATR and Their Use to Understand Binding Specificity of ATR Inhibitors.
J. Mol. Biol., 429, 2017
5GPN
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ARCHITECTURE OF MAMMALIAN RESPIRASOME
Descriptor:Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 2, ...
Authors:Gu, J., Wu, M., Guo, R., Yang, M.
Deposit date:2016-08-03
Release date:2017-04-05
Last modified:2017-04-12
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:The architecture of the mammalian respirasome.
Nature, 537, 2016
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