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1Z86
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SOLUTION STRUCTURE OF THE PDZ DOMAIN OF ALPHA-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Xu, W., Wen, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
1Z87
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SOLUTION STRUCTURE OF THE SPLIT PH-PDZ SUPRAMODULE OF ALPHA-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Xu, W., Wen, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
2ADZ
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SOLUTION STRUCTURE OF THE JOINED PH DOMAIN OF ALPHA1-SYNTROPHIN
Descriptor:Alpha-1-syntrophin
Authors:Yan, J., Wen, W., Xu, W., Long, J.F., Adams, M.E., Froehner, S.C., Zhang, M.
Deposit date:2005-07-21
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
2D2C
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CRYSTAL STRUCTURE OF CYTOCHROME B6F COMPLEX WITH DBMIB FROM M. LAMINOSUS
Descriptor:Cytochrome b6, Cytochrome b6-f complex subunit 4, Apocytochrome f, ...
Authors:Yan, J., Kurisu, G., Cramer, W.A.
Deposit date:2005-09-07
Release date:2005-12-13
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex
Proc.Natl.Acad.Sci.USA, 103, 2006
5GI0
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CRYSTAL STRUCTURE OF RNA EDITING FACTOR MORF9/RIP9
Descriptor:Multiple organellar RNA editing factor 9, chloroplastic
Authors:Yan, J., Zhang, Q., Guan, Z., Zou, T., Yin, P.
Deposit date:2016-06-21
Release date:2017-05-10
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing
Nat Plants, 3, 2017
5IWB
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CRYSTAL STRUCTURE OF DESIGN PENTATRICOPEPTIDE REPEAT COMPLEX WITH MORF PROTEIN
Descriptor:Multiple organellar RNA editing factor 9, chloroplastic, PLS3-PPR
Authors:Yan, J., Zhang, Q., Guan, Z., Zou, T., Yin, P.
Deposit date:2016-03-22
Release date:2017-03-29
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Structural basis for designer pentatricopeptide repeat proteins interaction with MORF protein
To be published
5IWW
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CRYSTAL STRUCTURE OF RNA EDITING FACTOR OF DESIGNER PLS-TYPE PPR/9R PROTEIN IN COMPLEX WITH MORF9/RIP9
Descriptor:Multiple organellar RNA editing factor 9, chloroplastic, PLS9-PPR
Authors:Yan, J., Zhang, Q., Guan, Z., Zou, T., Yin, P.
Deposit date:2016-03-23
Release date:2017-03-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing
Nat Plants, 3, 2017
5IZW
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CRYSTAL STRUCTURE OF RNA EDITING SPECIFIC FACTOR OF DESIGNER PLS-TYPE PPR-9R PROTEIN
Descriptor:PLS9-PPR
Authors:Yan, J., Zhang, Q., Guan, Z., Zou, T., Yin, P.
Deposit date:2016-03-26
Release date:2017-03-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.738 Å)
Cite:MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing
Nat Plants, 3, 2017
5N35
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GADOLINIUM PHASED PBP2 (SSO6202) AT 2.2 ANG
Descriptor:PolB1 Binding Protein 2 (PBP2), GADOLINIUM ATOM, GLYCEROL, ...
Authors:Yan, J., Beattie, T.R., Rojas, A.L., Schermerhorn, K., Gristwood, T., Trinidad, J.C., Albers, S.V., Roversi, P., Gardner, A.F., Abrescia, N.G.A., Bell, S.D.
Deposit date:2017-02-08
Release date:2017-05-17
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
Nat Commun, 8, 2017
5N41
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ARCHAEAL DNA POLYMERASE HOLOENZYME - SSO6202 AT 1.35 ANG RESOLUTION
Descriptor:PolB1 Binding Protein 2, 1,2-ETHANEDIOL
Authors:Yan, J., Beattie, T.R., Rojas, A.L., Schermerhorn, K., Gristwood, T., Trinidad, J.C., Albers, S.V., Roversi, P., Gardner, A.F., Abrescia, N.G.A., Bell, S.D.
Deposit date:2017-02-09
Release date:2017-05-17
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.351 Å)
Cite:Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.
Nat Commun, 8, 2017
3MGM
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CRYSTAL STRUCTURE OF HUMAN NUDT16
Descriptor:U8 snoRNA-decapping enzyme
Authors:Yan, J., Lu, G., Zhang, J., Qi, J., Li, Z., Gao, F.
Deposit date:2010-04-07
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
3K1R
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STRUCTURE OF HARMONIN NPDZ1 IN COMPLEX WITH THE SAM-PBM OF SANS
Descriptor:Harmonin, Usher syndrome type-1G protein
Authors:Pan, L., Yan, J., Zhang, M.
Deposit date:2009-09-28
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins
Proc.Natl.Acad.Sci.USA, 107, 2010
5JYY
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STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
4BZB
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CRYSTAL STRUCTURE OF THE TETRAMERIC DGTP-BOUND SAMHD1 MUTANT CATALYTIC CORE
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Ji, X., Yang, H., Wu, Y., Yan, J., Mehrens, J., DeLucia, M., Hao, C., Gronenborn, A.M., Skowronski, J., Ahn, J., Xiong, Y.
Deposit date:2013-07-25
Release date:2013-10-23
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Mechanism of Allosteric Activation of Samhd1 by Dgtp
Nat.Struct.Mol.Biol., 20, 2013
4BZC
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CRYSTAL STRUCTURE OF THE TETRAMERIC DGTP-BOUND WILD TYPE SAMHD1 CATALYTIC CORE
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), MANGANESE (II) ION, ...
Authors:Ji, X., Yang, H., Wu, Y., Yan, J., Mehrens, J., DeLucia, M., Hao, C., Gronenborn, A.M., Skowronski, J., Ahn, J., Xiong, Y.
Deposit date:2013-07-25
Release date:2013-10-23
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Mechanism of Allosteric Activation of Samhd1 by Dgtp
Nat.Struct.Mol.Biol., 20, 2013
4QY0
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 IN COMPLEX WITH AVIAN RECEPTOR
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY2
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STRUCTURE OF H10 FROM HUMAN-INFECTING H10N8 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOG
Descriptor:hemagglutinin, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID
Authors:Wang, M., Zhang, W., Qi, J., Wang, F., Zhou, J., Bi, Y., Wu, Y., Sun, H., Liu, J., Huang, C., Li, X., Yan, J., Shu, Y., Shi, Y., Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
5GRJ
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CRYSTAL STRUCTURE OF HUMAN PD-L1 WITH MONOCLONAL ANTIBODY AVELUMAB
Descriptor:avelumab H chain, avelumab L chain, Programmed cell death 1 ligand 1
Authors:Liu, K., Tan, S., Chai, Y., Chen, D., Song, H., Zhang, C.W.-H., Shi, Y., Liu, J., Tan, W., Lyu, J., Gao, S., Yan, J., Qi, J., Gao, G.F.
Deposit date:2016-08-11
Release date:2016-11-02
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (3.206 Å)
Cite:Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody Heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2017-01-18
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.755 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
3I6K
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NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
3RE9
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CRYSTAL STRUCTURE OF SORTASEC1 FROM STREPTOCOCCUS SUIS
Descriptor:Sortase-like protein
Authors:Lu, G., Qi, J., Gao, F., Yan, J., Tang, J., Gao, G.F.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel "open-form" structure of sortaseC from Streptococcus suis
Proteins, 2011
3RL1
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HIV RT DERIVED PEPTIDE COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3RL2
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HIV NEF DERIVED PEPTIDE NEF73 COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011