Author results

3JZ3
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STRUCTURE OF THE CYTOPLASMIC SEGMENT OF HISTIDINE KINASE QSEC
Descriptor:Sensor protein qseC, SULFATE ION
Authors:Xie, W., Kwiatkowski, W., Choe, S., Center for Structures of Membrane Proteins (CSMP)
Deposit date:2009-09-22
Release date:2010-07-21
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Cytoplasmic Segment of Histidine Kinase Receptor QseC, a Key Player in Bacterial Virulence.
Protein Pept.Lett., 17, 2010
2PME
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THE APO CRYSTAL STRUCTURE OF THE GLYCYL-TRNA SYNTHETASE
Descriptor:Glycyl-tRNA synthetase
Authors:Xie, W.
Deposit date:2007-04-21
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2PMF
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THE CRYSTAL STRUCTURE OF A HUMAN GLYCYL-TRNA SYNTHETASE MUTANT
Descriptor:Glycyl-tRNA synthetase, CHLORIDE ION, GLYCEROL
Authors:Xie, W.
Deposit date:2007-04-21
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Long-range structural effects of a Charcot-Marie- Tooth disease-causing mutation in human glycyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1Q2R
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CHEMICAL TRAPPING AND CRYSTAL STRUCTURE OF A CATALYTIC TRNA GUANINE TRANSGLYCOSYLASE COVALENT INTERMEDIATE
Descriptor:RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), Queuine tRNA-ribosyltransferase, ZINC ION, ...
Authors:Xie, W., Liu, X., Huang, R.H.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
1Q2S
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CHEMICAL TRAPPING AND CRYSTAL STRUCTURE OF A CATALYTIC TRNA GUANINE TRANSGLYCOSYLASE COVALENT INTERMEDIATE
Descriptor:5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(PQ1)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3', RNA (5'-R(*AP*GP*CP*AP*CP*GP*GP*CP*UP*(N)P*UP*AP*AP*AP*CP*CP*GP*UP*GP*C)-3'), Queuine tRNA-ribosyltransferase, ...
Authors:Xie, W., Liu, X., Huang, R.H.
Deposit date:2003-07-25
Release date:2003-09-09
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate
Nat.Struct.Biol., 10, 2003
5CO4
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STRUCTURAL INSIGHTS INTO THE 2-OH METHYLATION OF C/U34 ON TRNA
Descriptor:Putative tRNA (cytidine(34)-2'-O)-methyltransferase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL
Authors:Xie, W., Pang, P., Wang, Z.
Deposit date:2015-07-19
Release date:2016-07-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the 2-OH methylation of C34 or U34 on tRNA
To Be Published
5EGN
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EST816 AS AN N-ACYL HOMOSERINE LACTONE DEGRADING ENZYME
Descriptor:Esterase
Authors:Xie, W., Liu, X., Cao, L., Liu, Y.
Deposit date:2015-10-27
Release date:2016-11-02
Method:X-RAY DIFFRACTION (2.636 Å)
Cite:Est816 as an N-Acyl homoserine lactone degrading enzyme
To Be Published
6EDB
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CRYSTAL STRUCTURE OF SRY.HCGAS-21BP DSDNA COMPLEX
Descriptor:Sex-determining region Y protein,Cyclic GMP-AMP synthase, DNA (5'-D(*CP*GP*AP*TP*CP*CP*GP*GP*GP*AP*TP*CP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*TP*TP*GP*TP*TP*TP*AP*GP*AP*TP*CP*CP*CP*GP*GP*AP*TP*C)-3'), ...
Authors:Xie, W., Lama, L., Adura, C., Glickman, J.F., Tuschl, T., Patel, D.J.
Deposit date:2018-08-09
Release date:2019-05-29
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6EDC
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HCGAS-16BP DSDNA COMPLEX
Descriptor:Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ...
Authors:Xie, W., Lama, L., Adura, C., Glickman, J.F., Tuschl, T., Patel, D.J.
Deposit date:2018-08-09
Release date:2019-05-29
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O47
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HUMAN CGAS CORE DOMAIN (K427E/K428E) BOUND WITH RU-521
Descriptor:Cyclic GMP-AMP synthase, CITRIC ACID, ZINC ION, ...
Authors:Xie, W., Lama, L., Adura, C., Glickman, J.F., Tuschl, T., Patel, D.J.
Deposit date:2019-02-28
Release date:2019-05-29
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
5H0J
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THE CRYSTAL STRUCTURE OF WT PEDOBACTER HEPARINUS SMUG2
Descriptor:Uncharacterized protein
Authors:Xie, W., Cao, W., Pang, P.
Deposit date:2016-10-04
Release date:2017-01-18
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:SMUG2 DNA glycosylase from Pedobacter heparinus as a new subfamily of the UDG superfamily
Biochem. J., 474, 2017
5H0K
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THE CRYSTAL STRUCTURE OF WT PEDOBACTER HEPARINUS SMUG2
Descriptor:Uncharacterized protein
Authors:Xie, W., Cao, W., Pang, P.
Deposit date:2016-10-04
Release date:2017-01-18
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:SMUG2 DNA glycosylase from Pedobacter heparinus as a new subfamily of the UDG superfamily
Biochem. J., 474, 2017
5H93
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CRYSTAL STRUCTURE OF GEOBACTER METALLIREDUCENS SMUG1
Descriptor:Geobacter metallireducens SMUG1
Authors:Xie, W., Cao, W., Zhang, Z., Shen, J.
Deposit date:2015-12-25
Release date:2016-04-27
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.176 Å)
Cite:Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
5H98
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CRYSTAL STRUCTURE OF GEOBACTER METALLIREDUCENS SMUG1
Descriptor:Geobacter metallireducens SMUG1
Authors:Xie, W., Cao, W., Zhang, Z., Shen, J.
Deposit date:2015-12-26
Release date:2016-04-27
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
5H99
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CRYSTAL STRUCTURE OF GEOBACTER METALLIREDUCENS SMUG1 MUTANT N58D
Descriptor:Geobacter metallireducens SMUG1
Authors:Xie, W., Cao, W., Zhang, Z., Shen, J.
Deposit date:2015-12-26
Release date:2016-04-27
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
5H9I
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CRYSTAL STRUCTURE OF GEOBACTER METALLIREDUCENS SMUG1 WITH XANTHINE
Descriptor:Geobacter metallireducens SMUG1, XANTHINE, GLYCEROL, ...
Authors:Xie, W., Cao, W., Zhang, Z., Shen, J.
Deposit date:2015-12-28
Release date:2016-04-27
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
5X3G
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THE WT UNG CRYSTAL STRUCTURE FROM NITRATIFRACTOR SALSUGINIS
Descriptor:Uracil-DNA glycosylase
Authors:Xie, W., Cao, W., Chen, R., Zhang, Z.
Deposit date:2017-02-06
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.021 Å)
Cite:An unconventional family 1 uracil DNA glycosylase in Nitratifractor salsuginis.
FEBS J., 284, 2017
5X3H
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THE Y81G MUTANT OF THE UNG CRYSTAL STRUCTURE FROM NITRATIFRACTOR SALSUGINIS
Descriptor:Uracil-DNA glycosylase
Authors:Xie, W., Chen, R., Cao, W., Zhang, Z.
Deposit date:2017-02-06
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An unconventional family 1 uracil DNA glycosylase in Nitratifractor salsuginis.
FEBS J., 284, 2017
6IO9
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THE STRUCTURE OF APO-UDGX
Descriptor:Phage SPO1 DNA polymerase-related protein, IRON/SULFUR CLUSTER, SULFATE ION
Authors:Xie, W., Tu, J.
Deposit date:2018-10-29
Release date:2019-07-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
6IOA
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THE STRUCTURE OF UDGX IN COMPLEX WITH URACIL
Descriptor:Phage SPO1 DNA polymerase-related protein, IRON/SULFUR CLUSTER, URACIL, ...
Authors:Xie, W., Tu, J.
Deposit date:2018-10-29
Release date:2019-07-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
6IOB
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THE STRUCTURE OF THE H109A MUTANT OF UDGX IN COMPLEX WITH URACIL
Descriptor:Phage SPO1 DNA polymerase-related protein, URACIL, IRON/SULFUR CLUSTER
Authors:Xie, W., Tu, J.
Deposit date:2018-10-29
Release date:2019-07-24
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
6IOC
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THE STRUCTURE OF THE H109Q MUTANT OF UDGX IN COMPLEX WITH URACIL
Descriptor:Phage SPO1 DNA polymerase-related protein, IRON/SULFUR CLUSTER, URACIL
Authors:Xie, W., Tu, J.
Deposit date:2018-10-29
Release date:2019-07-24
Method:X-RAY DIFFRACTION (1.624 Å)
Cite:Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
6IOD
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THE STRUCTURE OF UDGX IN COMPLEX WITH SINGLE-STRANDED DNA
Descriptor:Phage SPO1 DNA polymerase-related protein, DNA, IRON/SULFUR CLUSTER
Authors:Xie, W., Tu, J.
Deposit date:2018-10-29
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Suicide inactivation of the uracil DNA glycosylase UdgX by covalent complex formation.
Nat.Chem.Biol., 15, 2019
3CRM
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STRUCTURE OF TRNA DIMETHYLALLYLTRANSFERASE: RNA MODIFICATION THROUGH A CHANNEL
Descriptor:tRNA delta(2)-isopentenylpyrophosphate transferase
Authors:Huang, R.H., Xie, W., Zhou, C.
Deposit date:2008-04-07
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel
J.Mol.Biol., 367, 2007
3CRQ
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STRUCTURE OF TRNA DIMETHYLALLYLTRANSFERASE: RNA MODIFICATION THROUGH A CHANNEL
Descriptor:tRNA delta(2)-isopentenylpyrophosphate transferase, MAGNESIUM ION, DIPHOSPHATE
Authors:Huang, R.H., Xie, W., Zhou, C.
Deposit date:2008-04-07
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of tRNA Dimethylallyltransferase: RNA Modification through a Channel
J.Mol.Biol., 367, 2007