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6ISI
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STRUCTURE OF 9N-I DNA POLYMERASE INCORPORATION WITH 3'-CL IN THE ACTIVE SITE
Descriptor:DNA polymerase, DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*C)-3'), DNA (5'-D(P*AP*CP*GP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Linwu, S.W., Maestre-Reyna, M., Tsai, M.D., Tu, Y.H., Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISH
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STRUCTURE OF 9N-I DNA POLYMERASE INCORPORATION WITH 3'-AL IN THE ACTIVE SITE
Descriptor:DNA polymerase, DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*(DAL))-3'), DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*C)-3'), ...
Authors:Linwu, S.W., Maestre-Reyna, M., Tsai, M.D., Tu, Y.H., Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISG
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STRUCTURE OF 9N-I DNA POLYMERASE INCORPORATION WITH DG IN THE ACTIVE SITE
Descriptor:DNA polymerase, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*G)-3'), DNA (5'-D(*GP*AP*CP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*G)-3'), ...
Authors:Linwu, S.W., Maestre-Reyna, M., Tsai, M.D., Tu, Y.H., Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6ISF
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STRUCTURE OF 9N-I DNA POLYMERASE INCORPORATION WITH DT IN THE ACTIVE SITE
Descriptor:DNA polymerase, DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Linwu, S.W., Maestre-Reyna, M., Tsai, M.D., Tu, Y.H., Chang, W.H.
Deposit date:2018-11-16
Release date:2019-08-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6IS7
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STRUCTURE OF 9N-I DNA POLYMERASE INCORPORATION WITH DA IN THE ACTIVE SITE
Descriptor:DNA polymerase, DNA (5'-D(P*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*CP*A)-3'), DNA (5'-D(*AP*CP*TP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Linwu, S.W., Maestre-Reyna, M., Tsai, M.D., Tu, Y.H., Chang, W.H.
Deposit date:2018-11-15
Release date:2019-08-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Thermococcus sp. 9°N DNA polymerase exhibits 3'-esterase activity that can be harnessed for DNA sequencing.
Commun Biol, 2, 2019
6IPN
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MGDGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPM
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MGDCTP
Descriptor:DNA-directed DNA/RNA polymerase mu, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPL
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MGDATP
Descriptor:DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPK
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MN8OXODGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPJ
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNDTTP
Descriptor:DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPI
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNDCTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPH
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNDATP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPG
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POST-CATALYTIC COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING CYTOSINE AND MG-8OXODGMP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*(8OG))-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPF
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POST-CATALYTIC COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING CYTOSINE AND MN-8OXODGMP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*(8OG))-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPE
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POST-CATALYTIC COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING ADENINE AND MG-8OXODGMP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*(8OG))-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPD
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POST-CATALYTIC COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING ADENINE AND MN-8OXODGMP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*(8OG))-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AKH
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PRE-CATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING ADENINE AND INCOMING MN-DUMPNPP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-31
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK9
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PRE-CATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING CYTOSINE AND INCOMING CA-8OXODGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK8
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PRE-CATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH TEMPLATING ADENINE AND INCOMING CA-8OXODGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3', DNA (5'-D(*CP*GP*TP*A)-3'), ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK6
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNCTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK5
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEH
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNUTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-04
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEC
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNATP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-08-04
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
5ZLC
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BINARY COMPLEX OF HUMAN DNA POLYMERASE MU WITH MNDGTP
Descriptor:DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K., Wu, W.J., Tsai, M.D.
Deposit date:2018-03-27
Release date:2019-05-29
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
5XZW
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CRYSTAL STRUCTURE OF RAD53 1-466
Descriptor:Serine/threonine-protein kinase RAD53
Authors:Weng, J.H., Tsai, M.D.
Deposit date:2017-07-14
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56, 2017
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