Binary Complex of Human DNA Polymerase Mu with MgdATP

Summary for 6IPL

DescriptorDNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordsdna polymerase mu, dna break repair, transferase-dntp complex, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight41146.3
Chang, Y.K.,Wu, W.J.,Tsai, M.D. (deposition date: 2018-11-03, release date: 2019-05-29, Last modification date: 2019-06-12)
Primary citation
Chang, Y.K.,Huang, Y.P.,Liu, X.X.,Ko, T.P.,Bessho, Y.,Kawano, Y.,Maestre-Reyna, M.,Wu, W.J.,Tsai, M.D.
Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141:8489-8502, 2019
PubMed: 31067051 (PDB entries with the same primary citation)
DOI: 10.1021/jacs.9b01741
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.25110 1.1% 5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload